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  1. Obesity and overweight are major risk factors for several chronic diseases. There is limited systematic evaluation of risk equations that predict the likelihood of developing an obesity or overweight associate...

    Authors: Adam Ben Taieb, Erika Roberts, Maria Luckevich, Sara Larsen, Carel W. le Roux, Paulo Gomes de Freitas and Dingeman Wolfert
    Citation: Diabetology & Metabolic Syndrome 2022 14:186
    Content type: Review Published on:

  2. Hemoglobin glycation index (HGI), which is calculated by blood glucose and hemoglobin A1c(HbA1c), reflects the individual discrepancy in HbA1c. This study aimed to investigate the association between HGI/HbA1c...

    Authors: Ying Wei, Zhenyu Wu, Ying Wang, Guang Wang and Jia Liu
    Citation: Diabetology & Metabolic Syndrome 2022 14:185
    Content type: Research Published on:

  3. Insulin resistance (IR) was reported to be associated with renal function impairment, but little is known about the gender difference. Hence, our study aimed to investigate the relationship between IR (estimat...

    Authors: Chieh-An Lin, Wen-Cheng Li, Szu-Yu Lin, Yi-Chuan Chen, Wei Yu, Hsiung-Ying Huang, Xue-Jie Xiong and Jau-Yuan Chen
    Citation: Diabetology & Metabolic Syndrome 2022 14:184
    Content type: Research Published on:

  4. Diabetic foot ulcers (DFU) are one of the leading long-term complications experienced by patients with diabetes. Dipeptidyl Peptidase 4 inhibitors (DPP4is) are a class of antihyperglycemic medications prescrib...

    Authors: Venkat N. Vangaveti, Shaurya Jhamb, Oliver Hayes, Julie Goodall, Jacqueline Bulbrook, Kelvin Robertson, Erik Biros, Kunwarjit S. Sangla and Usman H. Malabu
    Citation: Diabetology & Metabolic Syndrome 2022 14:183
    Content type: Research Published on:

  5. Research suggests that fibrinogen (Fib) concentrations are used to assess the occurrence and severity of diabetic foot (DF) and to monitor the progression of diabetic foot in patients. However, its correlation...

    Authors: Jinying Zhang, Jiayu Lin, Bo Liang, Lijun Chen, Xinna Yang and Mimi Li
    Citation: Diabetology & Metabolic Syndrome 2022 14:182
    Content type: Brief Report Published on:

  6. As the nonalcoholic fatty liver disease (NAFLD) epidemic matures, understanding how metabolic changes in NAFLD development vary over the age distribution is important to guide precise prevention. We aimed to c...

    Authors: Yansong Lin, Xiongcai Feng, Xu Cao, Rong Miao, Yanhong Sun, Rui Li, Junzhao Ye and Bihui Zhong
    Citation: Diabetology & Metabolic Syndrome 2022 14:181
    Content type: Research Published on:

  7. Patients with diabetes are prone to asymptomatic hypoglycemia (AH) due to diminished ability to perceive the onset of hypoglycemia. However, the actual prevalence and influencing factors of AH in outpatients w...

    Authors: Bingkun Huang, Qiuhui Jiang, Ting Wu, Qingbao Shen, Wengui Wang, Shoubi Wang, Yinxiang Huang, Shunhua Wang, Peiying Huang, Mingzhu Lin, Xiulin Shi and Xuejun Li
    Citation: Diabetology & Metabolic Syndrome 2022 14:180
    Content type: Research Published on:

  9. There is a lack of nationally representative evidence from the U.S. investigating the relationships between depression and diabetes management behaviors. Our study aimed to assess the associations between diab...

    Authors: Tim C. Lai, Cassidi C. McDaniel and Chiahung Chou
    Citation: Diabetology & Metabolic Syndrome 2022 14:178
    Content type: Research Published on:

  10. Women with diabetes first diagnosed during pregnancy (overt diabetes) may be at the same risk level of adverse outcomes as those with known pregestational diabetes. We compared pregnancy outcomes between these...

    Authors: Maria Lúcia Oppermann, Maria Amélia Campos, Vânia Naomi Hirakata and Angela Jacob Reichelt
    Citation: Diabetology & Metabolic Syndrome 2022 14:177
    Content type: Research Published on:

  11. The serum creatinine-to-cystatin C ratio (Scr/Scys) has been suggested as a surrogate marker of muscle mass and a predictor of adverse outcomes in many diseases. However, the prognostic value of Scr/Scys in pa...

    Authors: Wen Wei, Shanggang Li, Jin Liu, Yong Liu, Kaihong Chen, Shiqun Chen, Mei Tu and Hong Chen
    Citation: Diabetology & Metabolic Syndrome 2022 14:176
    Content type: Research Published on:

  12. It is a growing importance to induce a new treatment approach to encourage weight loss but also to improve maintenance of lost weight. It has been shown that promotion of brown adipose tissue (BAT) function or...

    Authors: Marina Nikolic, Jovana Novakovic, Galina Ramenskaya, Vladimir Kokorekin, Nevena Jeremic and Vladimir Jakovljevic
    Citation: Diabetology & Metabolic Syndrome 2022 14:175
    Content type: Review Published on:

  14. Patients with metabolic syndrome (MS) have a higher incidence of cardiovascular disease (CVD), but the possible mechanisms are not fully understood and further exploration of the possible factors influencing t...

    Authors: Zhe Shu, Xiong Ding, Qing Yue, XiaoXu Ma, MinHong Liu, YunTao Wu, Peng Yang, Ying Wu, Yun Li and Shouling Wu
    Citation: Diabetology & Metabolic Syndrome 2022 14:173
    Content type: Research Published on:

  15. Compromised intestinal barrier integrity can be independently driven by hyperglycemia, and both hyperglycemia and intestinal barrier injury are associated with poor prognosis in critical illness. This study in...

    Authors: Yi-Feng Wang, Feng-Ming Liang, Min Liu, Li-Cheng Ding, Jiao-Jie Hui, Hong-Yang Xu and Li-Jun Liu
    Citation: Diabetology & Metabolic Syndrome 2022 14:172
    Content type: Research Published on:

  16. Nowadays, obesity is one of the largest public health problems worldwide. In the last few decades, there has been a marked increase in the obesity epidemic and its related comorbidities. Worldwide, more than 2...

    Authors: Feng-Yao Wu and Rui-Xing Yin
    Citation: Diabetology & Metabolic Syndrome 2022 14:171
    Content type: Review Published on:

  17. Systemic inflammation and oxidative burden in patients with type 2 diabetes mellitus (T2DM) causes deleterious cardiovascular outcomes. We sought to investigate the clinical antioxidative and anti-inflammatory...

    Authors: Sepehr Gohari, Tara Reshadmanesh, Hadi Khodabandehloo, Amir Karbalaee-Hasani, Hassan Ahangar, Shahram Arsang-Jang, Faramarz Ismail-Beigi, Mohsen Dadashi, Samin Ghanbari, Homa Taheri, Mojtaba Fathi, Muhammad Javad Muhammadi, Reyhaneh Mahmoodian, Atieh Asgari, Mohammadreza Tayaranian, Mehdi Moharrami…
    Citation: Diabetology & Metabolic Syndrome 2022 14:170
    Content type: Research Published on:

  18. Although physical activity is widely recommended for preventing and treating cardiovascular complications of type 2 diabetes mellitus (T2DM), the underlying mechanisms remain unknown. MicroRNA-126 (miR-126) is...

    Authors: Yixiao Ma, Hua Liu, Yong Wang, Junjie Xuan, Xing Gao, Huixian Ding, Chunlian Ma, Yanfang Chen and Yi Yang
    Citation: Diabetology & Metabolic Syndrome 2022 14:169
    Content type: Review Published on:

  19. The role of glycemic control, both prior and during hospitalization, on mortality from COVID-19 in diabetic patients is debated. Furthermore, it is not clear whether hyperglycemia has a direct effect or requir...

    Authors: Sara Madaschi, Eugenia Resmini, Silvia Bonfadini, Giulia Massari, Paola Gamba, Marco Sandri, Stefano Calza, Elena Cimino, Emanuela Zarra, Silvia Dotti, Cristina Mascadri, Barbara Agosti, Emirena Garrafa and Angela Girelli
    Citation: Diabetology & Metabolic Syndrome 2022 14:168
    Content type: Research Published on:

  20. It is still debatable whether glycated albumin/glycated hemoglobin A1C (GA/HbA1C) ratio is associated with metabolic dysfunction-associated fatty liver disease (MAFLD), and few studies have been conducted in t...

    Authors: Jun-Wei Wang, Chun-Hua Jin, Jiang-Feng Ke, Yi-Lin Ma, Yu-Jie Wang, Jun-Xi Lu, Mei-Fang Li and Lian-Xi Li
    Citation: Diabetology & Metabolic Syndrome 2022 14:167
    Content type: Research Published on:

  21. Evidence showed possible benefits of a less gestational weight gain (GWG) than the US Institute of Medicine (IOM) recommendation in gestational diabetes mellitus (GDM) pregnancy. Here, we aimed to explore an a...

    Authors: Xiaoqin Luo, Jiayi Gao, Zhangya He, Jing Ji, Wanyu Zhang, Pei Wu, Xiaoxiao Guo, Dan Cao, Zhangrui Xu, Chao Li and Yang Mi
    Citation: Diabetology & Metabolic Syndrome 2022 14:166
    Content type: Research Published on:

  22. Rheumatoid arthritis, metabolic syndrome (MS) and cardiovascular disease (CVD) are mutually connected. We aim to investigate the association between rheumatoid factor (RF) and MS in general population, explore...

    Authors: Lan Li, Donglai Feng, Jing Zeng, Peng Ye, Yao Chen and Dong Wei
    Citation: Diabetology & Metabolic Syndrome 2022 14:165
    Content type: Research Published on:

  23. During pandemic period, a single fast glycemia value (≥ 92 mg/dl) performed within the recommended time window for the risk level defined by the Italian guidelines, was considered an acceptable surrogate for G...

    Authors: Rosario D’Anna, Antonio Di Benedetto, Stefania Palella, Alessia Miceli, Paola Romeo and Francesco Corrado
    Citation: Diabetology & Metabolic Syndrome 2022 14:164
    Content type: Research Published on:

  24. Diabetic hepatopathy is a serious complication of poorly controlled diabetes mellitus. An efficient antidiabetic drug which keeps normal liver tissues is not available. The renin-angiotensin system has been re...

    Authors: Amal M. Mahfoz and Aya Y. Gawish
    Citation: Diabetology & Metabolic Syndrome 2022 14:163
    Content type: Research Published on:

  25. The hemoglobin glycation index (HGI) is the difference between measured and estimated glycation of hemoglobin. However, there is limited evidence to investigate the HGI and the clinical outcomes of acute coron...

    Authors: Jiayu Li, Yanguo Xin, Jingye Li, Li Zhou, Hui Qiu, Aidong Shen, Hui Chen and Hongwei Li
    Citation: Diabetology & Metabolic Syndrome 2022 14:162
    Content type: Research Published on:

  26. Insulin resistance (IR) is an important contributor to the development of hypertension (HTN), and the triglyceride-glucose (TyG) index has been proposed as a simple, reliable marker of IR. This study investiga...

    Authors: Dong-Hwa Lee, Jong Eun Park, So Young Kim, Hyun Jeong Jeon and Jong-Hyock Park
    Citation: Diabetology & Metabolic Syndrome 2022 14:161
    Content type: Research Published on:

  27. Several recent studies have found that Osteocalcin (OCN), a multifunctional protein secreted exclusively by osteoblasts, is beneficial to glucose metabolism and type 2 diabetes mellitus (T2DM). However, the ef...

    Authors: Haiyan Lei, Jun Liu, Wei Wang, Xinyi Yang, Zhouqin Feng, Pu Zang, Bin Lu and Jiaqing Shao
    Citation: Diabetology & Metabolic Syndrome 2022 14:160
    Content type: Research Published on:

  28. Asian Indians (AI) are at high risk for both atherosclerotic diseases (ATH) and diabetes mellitus (DM). We analyze the clustering of these two comorbidities as contributing causes of death in AI versus Non-AI ...

    Authors: Deepak R. Nair, Abhyuday Chauhan and Dhananjay Vaidya
    Citation: Diabetology & Metabolic Syndrome 2022 14:159
    Content type: Research Published on:

  29. We aimed to assess the impact of healthy cardiovascular health (CVH) on diabetic complications, mortality, and life expectancy among people with type 2 diabetes and to explore whether inflammation marker media...

    Authors: Yuan Zhang, Rongrong Yang, Yabing Hou, Yanchun Chen, Shu Li, Yaogang Wang and Hongxi Yang
    Citation: Diabetology & Metabolic Syndrome 2022 14:158
    Content type: Research Published on:

  30. Obstructive sleep apnea is a syndrome characterized by recurrent partial, or complete upper airway collapse during sleep. Although obstructive sleep apnea is common in type 2 diabetes mellitus, the majority of...

    Authors: Alemayehu Wondie, Mitku Mammo Taderegew, Betemariam Girma, Atsede Getawey, Daniel Tsega, Tamene Fetene Terefe, Shimelis Mitiku and Hiwot Berhanu
    Citation: Diabetology & Metabolic Syndrome 2022 14:157
    Content type: Research Published on:

  31. To evaluate the efficacy and safety of finerenone and sodium-glucose cotransporter-2 inhibitors (SGLT2i) on reducing new-onset of atrial fibrillation (AF) in patients with type 2 diabetes mellitus (T2DM) and c...

    Authors: Yaofu Zhang, Junheng Wang, Li Jiang, Tongxin Wang, Zhuang Li, Xiaozhe Fu, Weijun Huang, Yonghua Xiao, Shidong Wang and Jinxi Zhao
    Citation: Diabetology & Metabolic Syndrome 2022 14:156
    Content type: Review Published on:

  32. Diabetes is associated to a high financial and disease burden, explaining a large proportion of expenditure of the health system in one year. The purpose of this study was to estimate long-term costs and healt...

    Authors: Manuel Antonio Espinoza, Tomas Abbott, Alvaro Passi and Carlos Balmaceda
    Citation: Diabetology & Metabolic Syndrome 2022 14:155
    Content type: Research Published on:

  33. To assess the impact of long-acting insulin analogues, compared to intermediate acting neutral protamine Hagedron (NPH), on maternal, perinatal and neonatal outcomes.

    Authors: Jijiao Wang, Xiaochen Ji, Ting Liu and Nan Zhao
    Citation: Diabetology & Metabolic Syndrome 2022 14:154
    Content type: Review Published on:

  34. Previous studies have shown inconsistent conclusions regarding the association between incretin-based therapies and the risk of developing gallbladder or biliary diseases. We conducted a meta-analysis to evalu...

    Authors: Meng Yu, Zheng Yang, Chongxin Chen, Yuhuan Lv, Linyu Xiang, Subei Zhao and Rong Li
    Citation: Diabetology & Metabolic Syndrome 2022 14:153
    Content type: Research Published on:

  36. The aim of this systematic review and meta-analysis was to determine the effect of olive leaf extract (OLE) supplementation on cardiovascular-related variables, including lipid, glycemic, inflammatory, liver a...

    Authors: Elham Razmpoosh, Shima Abdollahi, Mahdieh Mousavirad, Cain C. T. Clark and Sepideh Soltani
    Citation: Diabetology & Metabolic Syndrome 2022 14:151
    Content type: Review Published on:

  37. Metabolically healthy obesity (MHO), has been recognized as a transient phenotype with few cardiometabolic diseases; however, little is known regarding the development of hypertension in subjects with an absen...

    Authors: Yue Yuan, Wei Sun and Xiangqing Kong
    Citation: Diabetology & Metabolic Syndrome 2022 14:150
    Content type: Research Published on:

  38. The clustering of metabolic abnormalities may weaken vaccine-induced immunity, but epidemiological data regarding SARS-CoV-2 vaccines are scarce. The present study aimed to examine the cross-sectional associat...

    Authors: Dong Van Hoang, Shohei Yamamoto, Ami Fukunaga, Yosuke Inoue, Tetsuya Mizoue and Norio Ohmagari
    Citation: Diabetology & Metabolic Syndrome 2022 14:149
    Content type: Research Published on:

  39. Diabetes-induced liver injury is a complication of diabetes mellitus of which there are no approved drugs for effective treatment or prevention. This study investigates possible hepatoprotective effect of alph...

    Authors: George J. Dugbartey, Karl K. Alornyo, Ismaila Adams, Stephen Atule, Richard Obeng-Kyeremeh, Daniel Amoah and Samuel Adjei
    Citation: Diabetology & Metabolic Syndrome 2022 14:148
    Content type: Research Published on:

  40. The hypothalamus of the central nervous system is implicated in the development of diabetes due to its glucose-sensing function. Dysregulation of the hypothalamic glucose-sensing neurons leads to abnormal gluc...

    Authors: Edina Pandur, István Szabó, Edina Hormay, Ramóna Pap, Attila Almási, Katalin Sipos, Viktória Farkas and Zoltán Karádi
    Citation: Diabetology & Metabolic Syndrome 2022 14:147
    Content type: Research Published on:

  41. Excess adipose tissue is associated with increased cardiovascular and metabolic risk, but the volume of visceral and subcutaneous adipose tissue poses different metabolic risks. MRI with fat suppression can be...

    Authors: Christine Haugen, Vegard Lysne, Ingfrid Haldorsen, Erling Tjora, Oddrun Anita Gudbrandsen, Jørn Vegard Sagen, Simon N. Dankel and Gunnar Mellgren
    Citation: Diabetology & Metabolic Syndrome 2022 14:146
    Content type: Research Published on:

  42. Measurement of estimated glucose disposal rate (eGDR) has been demonstrated to be an indicator of insulin resistance (IR) and a risk sign for long-term outcomes in those with ischemic heart disease and type 2 ...

    Authors: Chi Liu, Xiaoli Liu, Xiaoteng Ma, Yujing Cheng, Yan Sun, Dai Zhang, Qi Zhao and Yujie Zhou
    Citation: Diabetology & Metabolic Syndrome 2022 14:145
    Content type: Research Published on:

  43. Maternal complications of pregnancy, including hypertensive disorders of pregnancy, gestational diabetes mellitus, intrauterine growth restriction, preterm labour, and placental abruption, are associated with ...

    Authors: Emily Aldridge, Maleesa Pathirana, Melanie Wittwer, Susan Sierp, Shalem Y. Leemaqz, Claire T. Roberts, Gustaaf A. Dekker and Margaret A. Arstall
    Citation: Diabetology & Metabolic Syndrome 2022 14:144
    Content type: Research Published on:

  44. The nutrition transition in developing countries like Iran causes the increasing rise of obesity and abdominal obesity rates. However, it is not yet well proven that environmental modifications like improving ...

    Authors: Fatemeh Gholami, Mahsa Samadi, Neda Soveid and Khadijeh Mirzaei
    Citation: Diabetology & Metabolic Syndrome 2022 14:143
    Content type: Research Published on:

  45. Increased serum carcinoembryonic antigen (CEA) levels are reported to be associated with various metabolic and inflammatory diseases. This study assessed whether high-normal serum CEA is related to diabetic pe...

    Authors: Chun-hua Wang, Chao Yu, Lei Zhuang, Feng Xu, Li-hua Zhao, Xiao-hua Wang, Li-yan Ning, Xiu-lin Zhang, Dong-mei Zhang, Xue-qin Wang and Jian-bin Su
    Citation: Diabetology & Metabolic Syndrome 2022 14:142
    Content type: Research Published on:

  46. This study aimed to evaluate whether soluble vascular cytoadhesive molecule-1 (sVCAM-1), intracellular cytoadhesive molecule-1 (sICAM-1), and endothelial function as assessed by EndoPat outweighed traditional ...

    Authors: Alessandra Saldanha de Mattos Matheus, Maria de Fátima Bevilacqua da Matta, Eliete Leão Silva Clemente, Maria de Lourdes Guimarães Rodrigues, Débora Cristina Torres Valença, Karla Rezende Guerra Drummond and Marília Brito Gomes
    Citation: Diabetology & Metabolic Syndrome 2022 14:141
    Content type: Research Published on:

  47. An interprofessional medication adherence intervention led by pharmacists, combining motivational interviews and feedback with electronic monitor (EM) drug assessment, was offered to all consecutive patients w...

    Authors: Carole Bandiera, Liliane Lam, Isabella Locatelli, Jennifer Dotta-Celio, Dina Duarte, Gregoire Wuerzner, Menno Pruijm, Anne Zanchi and Marie P. Schneider
    Citation: Diabetology & Metabolic Syndrome 2022 14:140
    Content type: Research Published on:

  48. The purpose of this study was to investigate the psychometric properties of the Persian version of Diabetes Health Literacy Scale in type 2 diabetic patients.

    Authors: Mahdi Moshki, Ali Alami, Zohreh Zadehahmad, Mousa Ghelichi-Ghojogh, Mitra Dogonchi and Alireza Jafari
    Citation: Diabetology & Metabolic Syndrome 2022 14:139
    Content type: Research Published on:

    The Correction to this article has been published in Diabetology & Metabolic Syndrome 2022 14:174

  49. Chinese diabetes society has published the new diagnostic criteria for diabetes in China (2020 edition). We aimed to investigate the predictive value of new diabetes-diagnosed criteria for cardiovascular disea...

    Authors: Zixiang Ye, Yanxiang Gao, Enmin Xie, Yike Li, Ziyu Guo, Peizhao Li, Jingyi Ren and Jingang Zheng
    Citation: Diabetology & Metabolic Syndrome 2022 14:138
    Content type: Research Published on:

  50. Several studies have investigated the association of insulin resistance (IR) surrogates and the risk of hypertension. However, it is unclear whether there exist differences between different IR surrogates and ...

    Authors: Wenke Cheng, Fanliang Kong and Siwei Chen
    Citation: Diabetology & Metabolic Syndrome 2022 14:137
    Content type: Research Published on:

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