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  1. Evidence suggests that pathophysiological conditions such as obesity and type 2 diabetes (T2D) are associated with morphologic and metabolic alterations in the small intestinal mucosa. Exploring these alterati...

    Authors: Catherine Lalande, Jean-Philippe Drouin-Chartier, André J. Tremblay, Patrick Couture and Alain Veilleux

    Citation: Diabetology & Metabolic Syndrome 2020 12:31

    Content type: Research

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  2. Diabetes and diabetic complications are considered as leading causes of both morbidity and mortality in the world. Unfortunately, routine medical treatments used for affected patients possess undesirable side ...

    Authors: Mohammad Hossein Pourhanifeh, Azam Hosseinzadeh, Ehsan Dehdashtian, Karim Hemati and Saeed Mehrzadi

    Citation: Diabetology & Metabolic Syndrome 2020 12:30

    Content type: Review

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  3. Obesity and Overweight at an early age can contribute with many chronic diseases such as cancers, diabetes and cardiovascular diseases. Diet-related inflammation is one of the most important underlying mechani...

    Authors: Farhad Vahid, Fatemeh Bourbour, Maryam Gholamalizadeh, Nitin Shivappa, James R. Hébert, Khatereh Babakhani, Alireza Mosavi Jarrahi, Samaneh Mirzaei Dahka and Saeid Doaei

    Citation: Diabetology & Metabolic Syndrome 2020 12:29

    Content type: Research

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  4. Congenital generalized lipodystrophy (CGL) is a rare autosomal recessive disorder characterized by the near-total loss of subcutaneous adipose tissue soon after birth, resulting in ectopic fat deposition and s...

    Authors: Renan Magalhães Montenegro Junior, Grayce Ellen da Cruz Paiva Lima, Virgínia Oliveira Fernandes, Ana Paula Dias Rangel Montenegro, Clarisse Mourão Melo Ponte, Lívia Vasconcelos Martins, Daniel Pascoalino Pinheiro, Maria Elisabete Amaral de Moraes, Manoel Odorico de Moraes Filho and Catarina Brasil d’Alva

    Citation: Diabetology & Metabolic Syndrome 2020 12:28

    Content type: Research

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  5. This study aimed to assess the agreement and efficacy of the Ipswich Touch Test compared to the monofilament test in individuals with type 2 diabetes.

    Authors: Luz Marina Alfonso Dutra, Mirian Conceição Moura, Flaviene Alves do Prado, Giselle De Oliveira Lima, Manuela Costa Melo, Rubens Nelson Morato Fernandez and Maria Rita Carvalho Garbi Novaes

    Citation: Diabetology & Metabolic Syndrome 2020 12:27

    Content type: Research

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  7. Detecting early type 2 diabetes (T2D) risk factors may reduce or prevent the development of the disease. We conducted a pilot study to generate preliminary data on the perception of T2D and further determined ...

    Authors: Janet Antwi, Rebecca Lavin, Stacey Sullivan and Maria Bellavia

    Citation: Diabetology & Metabolic Syndrome 2020 12:25

    Content type: Research

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  9. Type 1 diabetes (T1D) affects psychologically not only the persons with diabetes themselves but affects their family members. Few studies were conducted to investigate mental health in T1D partners. This study...

    Authors: E. Buin, E. J. Pavin and M. S. V. M. Silveira

    Citation: Diabetology & Metabolic Syndrome 2020 12:23

    Content type: Research

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  10. The International Consensus in Time in Range (TIR) was recently released and defined the concept of the time spent in the target range between 70 and 180 mg/dL while reducing time in hypoglycemia, for patients...

    Authors: Monica Andrade Lima Gabbay, Melanie Rodacki, Luis Eduardo Calliari, Andre Gustavo Daher Vianna, Marcio Krakauer, Mauro Scharf Pinto, Janice Sepúlveda Reis, Marcia Puñales, Leonardo Garcia Miranda, Ana Claudia Ramalho, Denise Reis Franco and Hermelinda Pedrosa Cordeiro Pedrosa

    Citation: Diabetology & Metabolic Syndrome 2020 12:22

    Content type: Review

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  12. The use of highly active anti- retroviral therapy (HAART) as well as human immunodeficiency virus (HIV) per se have been shown to be related with diabetes among patients living with HIV. There is limited evide...

    Authors: Alemu Gebrie, Bekele Tesfaye, Tensae Gebru, Fentahun Adane, Worku Abie and Mekonnen Sisay

    Citation: Diabetology & Metabolic Syndrome 2020 12:20

    Content type: Research

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  13. Few studies examined associations between depressive symptoms and metabolic syndrome (MetS) among older Chinese adults. Considering that the prevalence of depressive symptoms is high in older Chinese adults, w...

    Authors: Jing-Hong Liu, Yu-Xi Qian, Qing-Hua Ma, Hong-Peng Sun, Yong Xu and Chen-Wei Pan

    Citation: Diabetology & Metabolic Syndrome 2020 12:18

    Content type: Research

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  14. Existing evidence suggest that low concentrations of vitamin A and E may have a contribution to the development of diabetes complications; however, data regarding the status of vitamin A and E among individual...

    Authors: Hebah Alawi Kutbi and Sahar Ali Hammouda

    Citation: Diabetology & Metabolic Syndrome 2020 12:17

    Content type: Research

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  15. Metabolic syndrome (MS) is a complex disorder represented by a set of cardiovascular risk factors usually related to central fat deposition, insulin resistance, hypertension and dyslipidemia. It is associated ...

    Authors: Ana Denise Brandão, Jeferson Hernandes da Silva, Sarah Mariane Oliveira Lima, Leiciane Lima, Bhianca Loize, Antônio Adolfo Mattos de Castro, Claudia Kümpel and Elias Ferreira Porto

    Citation: Diabetology & Metabolic Syndrome 2020 12:16

    Content type: Research

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  16. To adapt and validate the Clarke and Gold questionnaires and the Edinburgh Hypoglycemia Symptom Scale (EHSS) to Brazilian Portuguese and to determine the prevalence and risk factors associated with impaired aw...

    Authors: Paula Stefenon, André Luís Marques da Silveira, Luana Seminotti Giaretta, Cristiane Bauermann Leitão and Andrea Carla Bauer

    Citation: Diabetology & Metabolic Syndrome 2020 12:15

    Content type: Research

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  18. Obesity is associated with increased general mortality and comorbidities, it is multifactorial and some evidence has shown that sleep duration and shift work may be implicated in its pathogenesis.

    Authors: Maria Carlota Borba Brum, Fábio Fernandes Dantas Filho, Claúdia Carolina Schnorr, Otávio Azevedo Bertoletti, Gustavo Borchardt Bottega and Ticiana da Costa Rodrigues

    Citation: Diabetology & Metabolic Syndrome 2020 12:13

    Content type: Research

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  19. Human data supporting a role for endoplasmic reticulum (ER) stress and calcium dyshomeostasis in diabetes is scarce. Darier disease (DD) is a hereditary skin disease caused by mutations in the ATP2A2 gene encodin...

    Authors: Tara Ahanian, Philip Curman, Ivone U. S. Leong, Kerstin Brismar, Etty Bachar-Wikstrom, Martin Cederlöf and Jakob D. Wikstrom

    Citation: Diabetology & Metabolic Syndrome 2020 12:12

    Content type: Research

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  20. The primary objective of our study was to determine which factors influence health literacy (HL) in patients with type 1 diabetes (T1D) and type 2 diabetes (T2D), and the secondary one was to evaluate the infl...

    Authors: Marilia B. Gomes, Luiza Harcar Muniz, Laura Gomes Nunes Melo, Marcela Haas Pizarro, Bianca Senger Vasconcelos Barros, Deborah Conte Santos and Carlos Antonio Negrato

    Citation: Diabetology & Metabolic Syndrome 2020 12:11

    Content type: Research

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  21. Metabolic syndrome (MetS) has been suggested to be a risk factor for many cancers, including breast cancer. However, it remains unclear whether MetS predicts poor prognosis in women with breast cancer. A meta-...

    Authors: Peiting Li, Tianying Wang, Chen Zeng, Meng Yang, Gang Li, Jiang Han and Wei Wu

    Citation: Diabetology & Metabolic Syndrome 2020 12:10

    Content type: Research

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  22. Reduced serum level of taurine in type 2 diabetes mellitus (T2DM) was shown to be associated with the metabolic alterations and clinical complications of diabetes. Dietary supplementation with taurine may atte...

    Authors: Vahid Maleki, Reza Mahdavi, Fatemeh Hajizadeh-Sharafabad and Mohammad Alizadeh

    Citation: Diabetology & Metabolic Syndrome 2020 12:9

    Content type: Research

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  23. Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in patients with type 2 diabetes (T2DM). Carotid intima-media thickness (CIMT) is considered a preclinical stage of atherosclerosis....

    Authors: Yuan-Yuan Zhou, Hong-Mei Qiu, Ying Yang and Yuan-Yuan Han

    Citation: Diabetology & Metabolic Syndrome 2020 12:8

    Content type: Research

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  24. Serum retinol-binding protein 4 (RBP4) plays a critical role in insulin resistance. The mechanism behind the impact of laparoscopic sleeve gastrectomy (LSG) on glucose metabolism is unclear. Hence, we aimed to...

    Authors: Xingchun Wang, Yueye Huang, Jingyang Gao, Hang Sun, Muthukumaran Jayachandran and Shen Qu

    Citation: Diabetology & Metabolic Syndrome 2020 12:7

    Content type: Research

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  25. Dysglycaemia is defined by elevated glucose levels in the blood, commonly characterized by impaired fasting glucose, impaired glucose tolerance, elevated glycated haemoglobin, or diabetes mellitus (DM) diagnos...

    Authors: Camila Maciel De Oliveira, Luciane Viater Tureck, Danilo Alvares, Chunyu Liu, Andrea Roseli Vançan Russo Horimoto, Rafael de Oliveira Alvim, José Eduardo Krieger and Alexandre C. Pereira

    Citation: Diabetology & Metabolic Syndrome 2020 12:6

    Content type: Short report

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  26. Chloride is a key electrolyte that regulates the body fluid distribution. Accordingly, manipulating chloride kinetics by selecting a suitable diuretic could be an attractive strategy for correcting body fluid ...

    Authors: Hajime Kataoka and Yuichi Yoshida

    Citation: Diabetology & Metabolic Syndrome 2020 12:5

    Content type: Research

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  27. We compared the effects of sodium–glucose cotransporter 2 (SGLT2) inhibitors on renal function in participants with type 2 diabetes and chronic kidney disease (CKD) classified by degree of albuminuria.

    Authors: Akinobu Nakamura, Hideaki Miyoshi, Hiraku Kameda, Kumiko Yamashita and Yoshio Kurihara

    Citation: Diabetology & Metabolic Syndrome 2020 12:4

    Content type: Short report

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  28. New technologies are changing diabetes treatment and contributing better outcomes in developed countries. To our knowledge, no previous studies have investigated the comparative effect of sensor-based monitori...

    Authors: Luis Eduardo P. Calliari, Marcio Krakauer, Andre Gustavo Daher Vianna, Yashesvini Ram, Douglas Eugenio Barbieri, Yongjin Xu and Timothy C. Dunn

    Citation: Diabetology & Metabolic Syndrome 2020 12:3

    Content type: Research

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  29. The prevalence of metabolic syndrome varies among populations with different ethnicities. Asian populations develop metabolic complications at lower amounts of adiposity than western populations. The role of a...

    Authors: Fathimah S. Sigit, Dicky L. Tahapary, Stella Trompet, Erliyani Sartono, Ko Willems van Dijk, Frits R. Rosendaal and Renée de Mutsert

    Citation: Diabetology & Metabolic Syndrome 2020 12:2

    Content type: Research

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  30. Diabetes mellitus is an important risk factor for cardiomyopathy. Increasing oxidative stress may be one of the main factors of diabetic cardiomyopathy. A13, a newly synthesized curcumin analog, was proved to ...

    Authors: Lanting Xiang, Qiongying Zhang, Chen Chi, Gu Wu, Zhongmin Lin, Jianmin Li, Qianru Gu and Guorong Chen

    Citation: Diabetology & Metabolic Syndrome 2020 12:1

    Content type: Research

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  31. Type 2 diabetes mellitus (T2DM) and periodontitis are chronic inflammatory diseases with a bidirectional relationship. The uncontrolled levels of glucose in T2DM patients change the pathophysiology and balance...

    Authors: Juan Antonio Arreguin-Cano, Brenda Ayerdi-Nájera, Arvey Tacuba-Saavedra, Napoleón Navarro-Tito, Alfonso Dávalos-Martínez, Abel Emigdio-Vargas, Elia Barrera-Rodríguez, Nubia Blanco-García, Gloria Gutiérrez-Venegas, Elías Ventura-Molina and Gladys León-Dorantes

    Citation: Diabetology & Metabolic Syndrome 2019 11:113

    Content type: Research

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  33. This study investigates the effect of genistein (Gen) on the lipid profiles and expression of low-density lipoprotein receptor (LDLR), liver X receptor α (LXRα) and ATP-binding cassette transporter G1 (ABCG1) ...

    Authors: Tao Zhang and Xiao-Xing Chi

    Citation: Diabetology & Metabolic Syndrome 2019 11:111

    Content type: Research

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  34. The optimal revascularization technique in diabetic patients with complex coronary artery disease (CAD), including left main CAD and multivessel coronary disease (MVD), remains controversial. The current study...

    Authors: ChuanNan Zhai, HongLiang Cong, Kai Hou, YueCheng Hu, JingXia Zhang and YingYi Zhang

    Citation: Diabetology & Metabolic Syndrome 2019 11:110

    Content type: Research

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  35. Investigate effects of long-term exercise on the remodeling markers MMP-9, TIMP-1, EMMPRIN and Galectin-3 in combined type 2 diabetes mellitus (T2DM) and coronary artery disease (CAD) patients. Any association...

    Authors: Hani Zaidi, Rune Byrkjeland, Ida U. Njerve, Sissel Åkra, Svein Solheim, Harald Arnesen, Ingebjørg Seljeflot and Trine B. Opstad

    Citation: Diabetology & Metabolic Syndrome 2019 11:109

    Content type: Research

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  36. This study aimed to observe the hypoglycemic effect of cassia seed extract in rats with type-2 diabetes mellitus and its effect on reducing insulin resistance in the skeletal muscle.

    Authors: Qiu-Ying Wang, Ai-Hua Tong, Ying-Ying Pan, Xian-Dang Zhang, Wen-Yu Ding and Wen Xiong

    Citation: Diabetology & Metabolic Syndrome 2019 11:108

    Content type: Research

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  37. Evogliptin (EVO) is a potent and selective dipeptidyl peptidase-4 inhibitor (DPP4i) developed for the treatment of type 2 diabetes mellitus (T2DM). DPP4is are known to exhibit a better glucose-lowering effect ...

    Authors: Cintia Cercato, Joao Soares Felício, Luis Augusto Tavares Russo, Joao Lindolfo Cunha Borges, Joao Salles, Patricia Muskat, Teresa Bonansea, Antonio Roberto Chacra, Freddy Goldberg Eliaschewitz and Adriana Costa Forti

    Citation: Diabetology & Metabolic Syndrome 2019 11:107

    Content type: Research

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  38. There is lack of ideal and comprehensive economic evaluations of various GDM strategies. The aim of this study is to the compare efficacy and cost-effectiveness of five different methods of screening for gesta...

    Authors: Fahimeh Ramezani Tehrani

    Citation: Diabetology & Metabolic Syndrome 2019 11:106

    Content type: Study Protocol

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  39. South Africa has the largest population of human immunodeficiency virus (HIV) infected patients on antiretroviral therapy (ART) realising the benefits of increased life expectancy. However, this population may...

    Authors: Olamide O. Todowede, Benn Sartorius, Nombulelo Magula and Aletta E. Schutte

    Citation: Diabetology & Metabolic Syndrome 2019 11:105

    Content type: Research

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  40. Elevated rates of anxiety and depressive symptoms in Type 1 Diabetes patients (T1D) and high rates of diabetes-specific distress (DD) have been shown. Several factors may be responsible for increase the DD lev...

    Authors: M. S. V. M. Silveira, T. G. Bovi and E. J. Pavin

    Citation: Diabetology & Metabolic Syndrome 2019 11:104

    Content type: Short report

    Published on:

  41. The aim of this randomized, double-blinded, controlled trial was to investigate the effect of daily consumption of a synbiotic bread containing lactic acid on glycemic status, antioxidant biomarkers and inflam...

    Authors: Atie Ghafouri, Mitra Zarrati, Farzad Shidfar, Iraj Heydari, Raheleh Shokouhi Shoormasti and Omid Eslami

    Citation: Diabetology & Metabolic Syndrome 2019 11:103

    Content type: Research

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  42. Prediabetes has been proposed as a risk factor for the development of type 2 diabetes mellitus (DM2) and cardiovascular disease (CVD). Despite the clinical importance of prediabetes, little is known about the ...

    Authors: Jennifer Garay, Paul A. Camacho, Jose Lopez-Lopez, Juliana Alvernia, Marcela Garcia, Daniel D. Cohen, Carlos Calderon and Patricio Lopez-Jaramillo

    Citation: Diabetology & Metabolic Syndrome 2019 11:102

    Content type: Research

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  43. The present study was designed to determine whether zinc supplementation would increase the effects of restricted calorie diet (RCD) on obesity.

    Authors: Hoda Khorsandi, Omid Nikpayam, Reyhaneh Yousefi, Maryam Parandoosh, Nima Hosseinzadeh, Atoosa Saidpour and Arman Ghorbani

    Citation: Diabetology & Metabolic Syndrome 2019 11:101

    Content type: Research

    Published on:

  44. Although bilirubin has been generally regarded as a waste with potential neurotoxicity at high levels, a few clinical studies suggest a potential protective role of physiological serum total bilirubin (TBIL) c...

    Authors: Pijun Yan, Zhihong Zhang, Ying Miao, Yong Xu, Jianhua Zhu and Qin Wan

    Citation: Diabetology & Metabolic Syndrome 2019 11:100

    Content type: Research

    Published on:

  45. Alpha-synuclein (SNCA) as the presynaptic protein is expressed in different tissues and prevents insulin-resistance (IR) through increasing glucose-uptake by adipocytes and muscles. However, the effect of insu...

    Authors: Amirhosein Khoshi, Golnaz Goodarzi, Rezvan Mohammadi, Roghaye Arezumand, Meysam Moghbeli and Mahnaz Najariyan

    Citation: Diabetology & Metabolic Syndrome 2019 11:99

    Content type: Research

    Published on:

  46. Epigenetic changes in visceral adipose tissue (VAT) with obesity and their effects on gene expression are poorly understood, especially during emergent obesity in youth. The current study tested the hypothesis...

    Authors: Matthew D. Barberio, Evan P. Nadler, Samantha Sevilla, Rosemary Lu, Brennan Harmon and Monica J. Hubal

    Citation: Diabetology & Metabolic Syndrome 2019 11:98

    Content type: Research

    Published on:

  47. The association of diabetic nephropathy (DN) risk with single nucleotide polymorphisms (SNPs) within Engulfment and Cell Motility 1 (ELMO1) gene and gene–environment synergistic effect have not been extensively e...

    Authors: Yi Hou, Yong Gao, Yan Zhang, Si-Tong Lin, Yue Yu and Liu Yang

    Citation: Diabetology & Metabolic Syndrome 2019 11:97

    Content type: Research

    Published on:

  48. To investigate effects of metformin on the regulation of proteins of white adipose tissue (WAT) and brown adipose tissue (BAT) in obesity and explore the underlying mechanisms on energy metabolism.

    Authors: Tao Yuan, Juan Li, Wei-Gang Zhao, Wei Sun, Shuai-Nan Liu, Quan Liu, Yong Fu and Zhu-Fang Shen

    Citation: Diabetology & Metabolic Syndrome 2019 11:96

    Content type: Research

    Published on:

  49. Insulin resistance (IR) is frequently observed in patients with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE). In clinical practice, IR assessment is limited to a low proportion of patients d...

    Authors: Betsabe Contreras-Haro, Sandra Ofelia Hernandez-Gonzalez, Laura Gonzalez-Lopez, Maria Claudia Espinel-Bermudez, Leonel Garcia-Benavides, Edsaul Perez-Guerrero, Maria Luisa Vazquez-Villegas, Jose Antonio Robles-Cervantes, Mario Salazar-Paramo, Diana Mercedes Hernandez-Corona, Arnulfo Hernan Nava-Zavala and Jorge I. Gamez-Nava

    Citation: Diabetology & Metabolic Syndrome 2019 11:95

    Content type: Research

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  50. Treatment with metformin, the biguanide of hepatic insulin sensitizer, in patients with non-alcoholic fatty liver disease (NAFLD) has been reported with contradictory findings regarding the effectiveness on bl...

    Authors: Yi Sui, Xianhe Kong, Rongrong Fan, Yanbin Ye, Haiyan Mai, Shuyu Zhuo, Wei Lu, Peishan Ruan, Shi Fang and Tao Yang

    Citation: Diabetology & Metabolic Syndrome 2019 11:94

    Content type: Research

    Published on:


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