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  1. This study aimed to examine the effects of l-citrulline (l-CIT) on low-grade inflammation (meta-inflammation) and insulin sensitivity in type 2 diabetes (T2D) patients since it has exhibited hypoglycemic and anti...

    Authors: Fatemeh Abbaszadeh, Samaneh Azizi, Majid Mobasseri and Mehrangiz Ebrahimi-Mameghani

    Citation: Diabetology & Metabolic Syndrome 2021 13:52

    Content type: Research

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  2. The adipokine asprosin, which was recently discovered, facilitates hepatic glucose production. The aim of this study is to see whether serum asprosin concentrations are linked to diabetic nephropathy (DN).

    Authors: Rui Wang, Peng Lin, Huibo Sun and Wenchao Hu

    Citation: Diabetology & Metabolic Syndrome 2021 13:51

    Content type: Research

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  3. Hesperidin, a natural flavanone, has been proven to have multiple protective effects in diabetic rats, such as antioxidant, anti-inflammatory and anti-apoptotic effects. However, the molecular mechanisms under...

    Authors: Miao Tian, Yu-Bo Han, Cheng-Cheng Zhao, Li Liu and Fu-Li Zhang

    Citation: Diabetology & Metabolic Syndrome 2021 13:50

    Content type: Research

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  4. As a subcomponent of low-density lipoprotein cholesterol (LDL-C), small dense LDL-C (sdLDL-C) has been suggested to be a better predictor of cardiovascular diseases (CVD). The aim of this research was to evalu...

    Authors: Li Xu, Xu Chen, Jingfen Lu, Yan Xu, Honglin Yang, Xuewen Zhou, Jun Zhou, Jianhong Xu and Hao Shen

    Citation: Diabetology & Metabolic Syndrome 2021 13:49

    Content type: Research

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  5. Atherosclerosis cardiovascular disease (ASCVD) is the main cause of morbidity and mortality in type 2 diabetes mellitus (T2DM). As most diabetic patients with ASCVD are asymptomatic, it is most neglected in cl...

    Authors: Lu Gao, Wei Zhao, Jin-Kui Yang and Ming-Zhao Qin

    Citation: Diabetology & Metabolic Syndrome 2021 13:48

    Content type: Research

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  6. This claims-based retrospective cohort study examined the prevalence and incremental impact of non-alcoholic steatohepatitis among children with type 2 diabetes mellitus in the United States. Although diagnose...

    Authors: Lauren Parlett, Qinli Ma, Qian Shi, Geoffrey Crawford, Laura Herrera Scott, Vincent Willey and Abiy Agiro

    Citation: Diabetology & Metabolic Syndrome 2021 13:47

    Content type: Letter to the Editor

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  7. Bariatric surgery can alleviate cardiovascular risk via effects on cardiovascular disease (CVD) risk factors such as diabetes mellitus, hypertension, and dyslipidemia. Our study aimed to assess the cholesterol...

    Authors: Himani Thakkar, Vinnyfred Vincent, Sakshi Sukhla, Manraj Sra, Uma Kanga, Sandeep Aggarwal and Archna Singh

    Citation: Diabetology & Metabolic Syndrome 2021 13:46

    Content type: Research

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  8. HbA1c variability is independent of mean HbA1c, and associated with mortality due to vascular complications. However, the significance of HbA1c variability is unknown at present. In this study, we used flash g...

    Authors: Akemi Tokutsu, Yosuke Okada, Keiichi Torimoto and Yoshiya Tanaka

    Citation: Diabetology & Metabolic Syndrome 2021 13:45

    Content type: Research

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  9. The impact of subcutaneous fat accumulation remains controversial. This study assessed the association between visceral or subcutaneous fat area (VFA and SFA, respectively) and diabetes mellitus (DM) among Jap...

    Authors: Hirohide Yokokawa, Hiroshi Fukuda, Mizue Saita, Kento Goto, Tengen Kaku, Taiju Miyagami, Yuichi Takahashi, Chieko Hamada, Teruhiko Hisaoka and Toshio Naito

    Citation: Diabetology & Metabolic Syndrome 2021 13:44

    Content type: Research

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  10. Metformin plays a consolidated role in the management of polycystic ovary syndrome (PCOS). However, there is no clear answer on how long we should treat and on how long its beneficial impact sustain after we s...

    Authors: Nika Aleksandra Kravos, Andrej Janež, Katja Goričar, Vita Dolžan and Mojca Jensterle

    Citation: Diabetology & Metabolic Syndrome 2021 13:43

    Content type: Research

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  11. Continuous glucose monitoring systems are increasingly being adopted as an alternative to self-monitoring of blood glucose (SMBG) by persons with diabetes mellitus receiving insulin therapy.

    Authors: Marcio Krakauer, Jose Fernando Botero, Fernando J. Lavalle-González, Adrian Proietti and Douglas Eugenio Barbieri

    Citation: Diabetology & Metabolic Syndrome 2021 13:42

    Content type: Review

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  12. Obesity is considered a major health concern and mounting evidence suggests that the exposure to environmental endocrine disruptors, including Bisphenol-A (BPA), may enhance the risk to develop the disease. Mo...

    Authors: Amin Salehpour, Farzad Shidfar, Mehdi Hedayati, Ali Asghar Farshad, Asal Neshatbini Tehrani and Saeed Mohammadi

    Citation: Diabetology & Metabolic Syndrome 2021 13:41

    Content type: Research

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  13. The aim of the present study was to assess diabetes-related distress in inpatients and its association with metabolic control in people with diabetes type 1 (DM1) and type 2 (DM2).

    Authors: Nadine Kuniss, Guido Kramer, Ulrich A. Müller, Gunter Wolf and Christof Kloos

    Citation: Diabetology & Metabolic Syndrome 2021 13:40

    Content type: Research

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  14. To investigate the effects of intermittently scanned continuous glucose monitoring (isCGM) on blood glucose control, clinical value of blood glucose monitoring and production of urinary ketone bodies in preges...

    Authors: Shu-ying Li, Hang Guo, Yi Zhang, Pei Li, Pei Zhou, Li-rong Sun, Jing Li and Li-ming Chen

    Citation: Diabetology & Metabolic Syndrome 2021 13:39

    Content type: Research

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  15. The exact incidence, clinical features and uniform diagnostic criteria of exogenous insulin autoimmune syndrome (EIAS) are still unclear. The purpose of this study is to explore the clinical characteristics of...

    Authors: Zuojun Li, Dan Yi, Lijuan Zheng, Shiran Li, Weijin Fang and Chunjiang Wang

    Citation: Diabetology & Metabolic Syndrome 2021 13:38

    Content type: Research

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  16. This study aimed to explore predictive factors of time below target glucose range (TBR) ≥ 1% among patients’ characteristics and glycemic variability (GV) indices using continuous glucose monitoring data in el...

    Authors: Takahisa Handa, Akinobu Nakamura, Aika Miya, Hiroshi Nomoto, Hiraku Kameda, Kyu Yong Cho, So Nagai, Narihito Yoshioka, Hideaki Miyoshi and Tatsuya Atsumi

    Citation: Diabetology & Metabolic Syndrome 2021 13:37

    Content type: Research

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  17. Gut leakage has been shown to associate with low-grade inflammation and lower cardiorespiratory fitness in diabetic subjects. We aimed to investigate whether gut leakage markers related to cardiorespiratory fi...

    Authors: Susanne Kristine Aune, Rune Byrkjeland, Svein Solheim, Harald Arnesen, Marius Trøseid, Ayodeji Awoyemi, Ingebjørg Seljeflot and Ragnhild Helseth

    Citation: Diabetology & Metabolic Syndrome 2021 13:36

    Content type: Research

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  18. Traditional anthropometric indices are used in diagnosing metabolic syndrome (MetS). This study aimed to propose a novel index, a product of waist and neck circumferences (PWNC), and compared its value with tr...

    Authors: Yunhong Huang, Liping Gu, Na Li, Fang Fang, Xiaoying Ding, Yufan Wang and Yongde Peng

    Citation: Diabetology & Metabolic Syndrome 2021 13:35

    Content type: Research

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  19. Asprosin, a novel adipokine that raises glucose levels and stimulates appetite, has been proved to be pathologically increased in populations predisposed to type 2 diabetes mellitus (T2DM), obesity, and cardio...

    Authors: Aijun Jiang, Zhanrong Feng, Lu Yuan, Ying Zhang, Qian Li and Yuqing She

    Citation: Diabetology & Metabolic Syndrome 2021 13:34

    Content type: Research

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  20. Data on non-alcoholic fatty liver disease (NAFLD) in individuals with type 1 diabetes (T1D) is controversial and so far, there are no published data on the Brazilian population. We investigated the prevalence ...

    Authors: Bianca Senger Vasconcelos Barros, Fernanda Cruz Monteiro, Carlos Terra and Marilia Brito Gomes

    Citation: Diabetology & Metabolic Syndrome 2021 13:33

    Content type: Research

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  21. Overweight and obesity are a worldwide public health problem. Obesity prevalence has increased considerably, which indicates the need for more studies to better understand these diseases and related complicati...

    Authors: Mariana de Moura e Dias, Sandra Aparecida dos Reis, Lisiane Lopes da Conceição, Catarina Maria Nogueira de Oliveira Sediyama, Solange Silveira Pereira, Leandro Licursi de Oliveira, Maria do Carmo Gouveia Peluzio, J. Alfredo Martinez and Fermín Ignacio Milagro

    Citation: Diabetology & Metabolic Syndrome 2021 13:32

    Content type: Review

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  22. Due to diverging international recommendations, the unclear role of HbA1c and the lack of longitudinal data, we investigated the accuracy of diagnostic tests in the early and late postpartum in women with gest...

    Authors: Dan Yedu Quansah, Justine Gross, Richard Mbundu-Ilunga and Jardena J. Puder

    Citation: Diabetology & Metabolic Syndrome 2021 13:31

    Content type: Research

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  23. In the current study, we aimed to investigate the association of dietary inflammation scores (DIS) and lifestyle inflammation scores (LIS) with the risk of metabolic syndrome (MetS) in a prospective population...

    Authors: Hossein Farhadnejad, Karim Parastouei, Hosein Rostami, Parvin Mirmiran and Fereidoun Azizi

    Citation: Diabetology & Metabolic Syndrome 2021 13:30

    Content type: Research

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  24. Chronic inflammation is associated with the development, progression and long-term complications of type 2 diabetes. Hyperglycemia is associated with chronic low-grade inflammation, and thus has become the foc...

    Authors: Amanda L. Missel, Laura R. Saslow, Dina H. Griauzde, Donna Marvicsin, Ananda Sen, Caroline R. Richardson and Xuefeng Liu

    Citation: Diabetology & Metabolic Syndrome 2021 13:29

    Content type: Research

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  25. Dipeptidyl peptidase 4 (DPP4) is a serine exopeptidase able to inactivate various oligopeptides, and also a hepatokine. Hepatocyte-specific overexpression of DPP4 is associated with hepatic insulin resistance ...

    Authors: Sachiko Hattori, Kazuomi Nomoto, Tomohiko Suzuki and Seishu Hayashi

    Citation: Diabetology & Metabolic Syndrome 2021 13:28

    Content type: Short report

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  26. Protein phosphatase 4 regulatory subunit 1 (PP4R1) is one of the regulatory subunits of PP4. It has been determined to be involved in the regulation of TNF-α-induced hepatic insulin resistance and gluconeogene...

    Authors: Wenjing Li, Lanbo Peng, Chao Yang and Guangmin Chen

    Citation: Diabetology & Metabolic Syndrome 2021 13:27

    Content type: Research

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  27. The presence of metabolic syndrome among diabetes patients is frequent and is associated with an increased incidence of chronic complications and mortality. Despite several studies have been conducted, there i...

    Authors: Rebuma Belete, Zerihun Ataro, Ahmedmenewer Abdu and Merga Sheleme

    Citation: Diabetology & Metabolic Syndrome 2021 13:25

    Content type: Review

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  28. We conducted a systematic review and meta-analysis of clinical trials evaluating the role of vitamin C supplementation on lipid profiles among diabetic patients to summarize the available findings.

    Authors: Amare Abera Tareke and Addis Alem Hadgu

    Citation: Diabetology & Metabolic Syndrome 2021 13:24

    Content type: Review

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  29. Our understanding of the pathophysiology of the COVID-19 manifestations and evolution has improved over the past 10 months, but the reasons why evolution is more severe in obese and diabetic patients are not y...

    Authors: Andrey Santos, Daniéla Oliveira Magro, Rosana Evangelista-Poderoso and Mario José Abdalla Saad

    Citation: Diabetology & Metabolic Syndrome 2021 13:23

    Content type: Review

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  30. The aim of the study was to evaluate the ultrasound-derived measurements of the fetal soft-tissue, heart, liver and umbilical cord in pregnancies complicated by gestational (GDM) and type 1 diabetes mellitus (...

    Authors: Paweł Jan Stanirowski, Agata Majewska, Michał Lipa, Dorota Bomba-Opoń and Mirosław Wielgoś

    Citation: Diabetology & Metabolic Syndrome 2021 13:22

    Content type: Research

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  31. Diabetic encephalopathy is a severe diabetes complication with cognitive dysfunction and neuropsychiatric disability. The mechanisms underlying diabetic encephalopathy is believed to be relevant with oxidative...

    Authors: Chengfeng Miao, Hanbin Chen, Yulian Li, Ying Guo, Feifei Xu, Qi Chen, Yanyan Zhang, Mengjun Hu and Guorong Chen

    Citation: Diabetology & Metabolic Syndrome 2021 13:21

    Content type: Research

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  32. Previous studies reported that common functional variants (rs780093, rs780094, and rs1260326) in the glucokinase regulator gene (GCKR) were associated with metabolic syndrome despite the simultaneous association ...

    Authors: Asiyeh Sadat Zahedi, Mahdi Akbarzadeh, Bahareh Sedaghati-Khayat, Atefeh Seyedhamzehzadeh and Maryam S. Daneshpour

    Citation: Diabetology & Metabolic Syndrome 2021 13:20

    Content type: Research

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  33. Bariatric surgery, especially Roux-en-Y gastric bypass (RYGB), is the most effective and durable treatment option for severe obesity. The mechanisms involving adipose tissue may be important to explain the eff...

    Authors: Rafael Ferraz-Bannitz, Caroline Rossi Welendorf, Priscila Oliveira Coelho, Wilson Salgado Jr, Carla Barbosa Nonino, Rebeca A. Beraldo and Maria Cristina Foss-Freitas

    Citation: Diabetology & Metabolic Syndrome 2021 13:19

    Content type: Research

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  34. Polycystic ovary syndrome (PCOS) is a common endocrine disease affecting women of reproductive age and associated with reproductive and metabolic dysfunction. Few studies are available regarding metabolic trai...

    Authors: Poli Mara Spritzer, Ramon Bossardi Ramos, Lucas Bandeira Marchesan, Monica de Oliveira and Enrico Carmina

    Citation: Diabetology & Metabolic Syndrome 2021 13:18

    Content type: Research

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  35. Glucagon-like peptide-1 receptor (GLP-1R) activation may improve myocardial performance in the context of ischaemia, independent of glycaemic control, in individuals with and without type 2 diabetes mellitus.

    Authors: Aung Myat, Simon R. Redwood, Satpal Arri, Bernard J. Gersh, Deepak L. Bhatt and Michael S. Marber

    Citation: Diabetology & Metabolic Syndrome 2021 13:17

    Content type: Research

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  36. The beneficial effects of polyphenols have been reported. This study aimed to investigate the effect of oral Ellagic acid (EA) supplement on insulin resistance (IR) and Fetuin-A and serum sirtuin1 (SIRT1) in t...

    Authors: Mahnaz Ghadimi, Farshad Foroughi, Sima Hashemipour, Mohammadreza Rashidi Nooshabadi, Mohammad Hossein Ahmadi, Mojtaba Ghadimi Yari, Maria Kavianpour and Hossein Khadem Haghighian

    Citation: Diabetology & Metabolic Syndrome 2021 13:16

    Content type: Research

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  37. Hypertriglyceridemia (HTG) is considered an independent risk factor for major adverse cardiovascular events (MACE).

    Authors: Yan-yan Qi, Li Yan, Zhong-min Wang, Xi Wang, Hua Meng, Wen-bo Li, Dong-chang Chen, Meng Li, Jun Liu and Song-tao An

    Citation: Diabetology & Metabolic Syndrome 2021 13:15

    Content type: Research

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  38. There is growing evidence that the C1qTNF-related protein (CTRP) family has a crucial role in the pathophysiology of metabolic disorders such as type 2 diabetes (T2D) and obesity. We sought to identify the ass...

    Authors: Ziba Majidi, Solaleh Emamgholipour, Abolfazl Omidifar, Soheil Rahmani Fard, Hossein Poustchi and Mehrnoosh Shanaki

    Citation: Diabetology & Metabolic Syndrome 2021 13:14

    Content type: Research

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  39. Type 2 diabetes is a common non-communicable disease that is responsible for about 9% of all deaths and a 25% reduction in life expectancy. However, nearly half of the diabetic patients are not aware of their ...

    Authors: Fateme Kianpour, Mohammad Fararouei, Jafar Hassanzadeh, Mohammadnabi Mohammadi and Mostafa Dianatinasab

    Citation: Diabetology & Metabolic Syndrome 2021 13:13

    Content type: Research

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  40. Insulin-related disorders, including insulin resistance, insulin insensitivity, and insulinemia, is considered early predictors of major chronic disease risk. Using a set of correlated nutrient as nutrient pat...

    Authors: Farshad Teymoori, Ebrahim Mokhtari, Pantea Salehi, Firoozeh Hosseini-Esfahani, Parvin Mirmiran and Fereidoun Azizi

    Citation: Diabetology & Metabolic Syndrome 2021 13:12

    Content type: Research

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  41. The daily peak in dopaminergic neuronal activity at the area of the biological clock (hypothalamic suprachiasmatic nuclei [SCN]) is diminished in obese/insulin resistant vs lean/insulin sensitive animals. The ...

    Authors: Shuqin Luo, Michael Ezrokhi, Nicholas Cominos, Tsung-Huang Tsai, Carl R. Stoelzel, Yelena Trubitsyna and Anthony H. Cincotta

    Citation: Diabetology & Metabolic Syndrome 2021 13:11

    Content type: Research

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  42. Obesity and Metabolic Syndrome have been associated with cardiovascular, diabetes and cancer incidence. Obesity is a state of inflammation. There are cross-talks between adipocyte, adipokines, pro-inflammatory...

    Authors: Kartika W. Taroeno-Hariadi, Mardiah S. Hardianti, Hemi Sinorita and Teguh Aryandono

    Citation: Diabetology & Metabolic Syndrome 2021 13:10

    Content type: Review

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  43. Endotrophin is one of the extracellular matrix proteins secreted by adipose tissue. In this study, we aimed to investigate the effects of changes in blood glucose levels on serum endotrophin levels secreted by...

    Authors: Sengul Aydin Yoldemir, Yucel Arman, Murat Akarsu, Ozgur Altun, Mustafa Ozcan and Tufan Tukek

    Citation: Diabetology & Metabolic Syndrome 2021 13:9

    Content type: Research

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  44. Sepsis is life-threatening disease with systemic inflammation and can lead to various diseases, including septic acute kidney injury (AKI). Recently, diverse circular RNAs (circRNAs) are considered to be invol...

    Authors: Heyun Li, Xia Zhang, Peng Wang, Xiaoyan Zhou, Haiying Liang and Caoni Li

    Citation: Diabetology & Metabolic Syndrome 2021 13:7

    Content type: Research

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  45. Diabetes mellitus (DM) could be classified as type 1 diabetes mellitus (T1DM), type 2 diabetes mellitus (T2DM), gestational diabetes mellitus (GDM) and others according to etiology and pathology. Diabetic neph...

    Authors: Wanwan Luo, Lingmin Zhang, Lingling Sheng, Zhencheng Zhang and Zaixing Yang

    Citation: Diabetology & Metabolic Syndrome 2021 13:6

    Content type: Research

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  46. A dysregulated host immune response is common in patients with COVID-19.

    Authors: Dafeng Liu, Yong Wang, Bennan Zhao, Lijuan Lan, Yaling Liu, Lei Bao, Hong Chen, Min Yang, Qingfeng Li and Yilan Zeng

    Citation: Diabetology & Metabolic Syndrome 2021 13:5

    Content type: Research

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  47. Metabolic syndrome is a cluster of conditions that occur together, increasing the risk of cardiovascular disease. However, the relationship between metabolic syndrome and dementia has remained controversial. U...

    Authors: Yeo Jin Kim, Sang Mi Kim, Dae Hyun Jeong, Sang-Kyu Lee, Moo-Eob Ahn and Ohk-Hyun Ryu

    Citation: Diabetology & Metabolic Syndrome 2021 13:4

    Content type: Research

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  48. Regarding the increasing prevalence of cardiometabolic abnormalities, and its association with non-communicable chronic diseases, providing preventive and therapeutic strategies is a priority. A randomized pla...

    Authors: Zahra Yari, Zahra Naser-Nakhaee, Elahe Karimi‐Shahrbabak, Makan Cheraghpour, Mehdi Hedayati, Seyede Marjan Mohaghegh, Shahrzad Ommi and Azita Hekmatdoost

    Citation: Diabetology & Metabolic Syndrome 2021 13:3

    Content type: Research

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