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  1. Type 2 diabetes (T2D) shows a high mortality rate, dependent on disease duration, comorbidities and glucose control over time. Data on patients with short disease duration are scanty.

    Authors: Edoardo Biancalana, Federico Parolini, Alessandro Mengozzi and Anna Solini

    Citation: Diabetology & Metabolic Syndrome 2020 12:47

    Content type: Research

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  2. Reduced sleep quality is common in advanced age. Poor sleep quality is associated with adverse outcomes, chiefly cardiovascular, in young and middle-aged subjects, possibly because of its association with meta...

    Authors: Alice Laudisio, Silvia Giovannini, Panaiotis Finamore, Luca Navarini, Domenico Paolo Emanuele Margiotta, Federica Vannetti, Claudio Macchi, Daniele Coraci, Isabella Imbimbo, Raffaello Molino-Lova, Claudia Loreti, Raffaele Antonelli Incalzi, Giuseppe Zuccalà and Luca Padua

    Citation: Diabetology & Metabolic Syndrome 2020 12:46

    Content type: Research

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  3. In current management of type 2 diabetes (T2DM), cardiovascular and renal prevention have become important targets to be achieved. In this context, a joint panel of four endocrinology societies from Brazil and...

    Authors: Marcello Casaccia Bertoluci, João Eduardo Nunes Salles, José Silva-Nunes, Hermelinda Cordeiro Pedrosa, Rodrigo Oliveira Moreira, Rui Manuel Calado da Silva Duarte, Davide Mauricio da Costa Carvalho, Fábio Rogério Trujilho, João Filipe Cancela dos Santos Raposo, Erika Bezerra Parente, Fernando Valente, Fábio Ferreira de Moura, Alexandre Hohl, Miguel Melo, Francisco Garcia Pestana Araujo, Rosa Maria Monteiro Castro de Araújo Principe…

    Citation: Diabetology & Metabolic Syndrome 2020 12:45

    Content type: Review

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  4. The role of serum fibroblast growth factor 19 (FGF19) in arteriosclerosis is not well known. In the present study, we aimed to explore whether serum FGF19 levels were related to arteriosclerosis parameters, in...

    Authors: Wang-shu Liu, Meng-jie Tang, Tian-li Xu, Jian-bin Su, Xue-qin Wang, Feng Xu, Dong-mei Zhang, Qing Zhu, Jie Cao and Hong Wang

    Citation: Diabetology & Metabolic Syndrome 2020 12:44

    Content type: Research

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  5. Glycosylphosphatidylinositol-specific phospholipase D (GPLD1) is responsible for cleaving membrane-associated glycosylphosphatidylinositol (GPI) molecules, which is affected by diabetes. We aimed to examine th...

    Authors: Farzad Abdolmaleki and Ali Heidarianpour

    Citation: Diabetology & Metabolic Syndrome 2020 12:43

    Content type: Research

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  6. Neuregulin 4 (Nrg4) is a novel neurotrophic adipokine associated with the development of diabetic peripheral neuropathy (DPN), however, the pathological mechanism remains poorly understood. The purpose of our ...

    Authors: Pijun Yan, Zhihong Zhang, Ying Miao, Yong Xu, Jianhua Zhu and Qin Wan

    Citation: Diabetology & Metabolic Syndrome 2020 12:42

    Content type: Research

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  7. Prediabetes can predispose the individual to type 2 diabetes in the long-term. The present study was conducted to determine the effectiveness of vitamin D and omega-3 co-supplementation on glycemic control and...

    Authors: Masoumeh Rajabi-Naeeni, Mahrokh Dolatian, Mostafa Qorbani and Amir Abbas Vaezi

    Citation: Diabetology & Metabolic Syndrome 2020 12:41

    Content type: Research

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  8. Diabetes mellitus in elderly represents an exceptional subset in the population vulnerable to cardiovascular events. As aging, diabetes mellitus and hypertension share common pathways, an ideal treatment shoul...

    Authors: Shaimaa M. Motawea, Rasha I. Noreldin and Yahya M. Naguib

    Citation: Diabetology & Metabolic Syndrome 2020 12:40

    Content type: Research

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  9. LncRNA HAND2-AS1 has been reported to be a tumor suppressor in several types of malignancy, while its involvement in other human diseases is unclear. Our preliminary RNA-seq analysis revealed the downregulatio...

    Authors: Changqing Dong, Shengmao Liu, Yanling Li and Yingchun Cui

    Citation: Diabetology & Metabolic Syndrome 2020 12:39

    Content type: Research

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  10. Emerging observational studies suggest an association between metabolic syndrome (MetS) and osteoarthritis (OA). This meta-analysis was conducted to examine whether or not there is a bidirectional relationship...

    Authors: Sheng-Yao Liu, Wen-Ting Zhu, Bin-Wei Chen, Yuan-Hong Chen and Guo-Xin Ni

    Citation: Diabetology & Metabolic Syndrome 2020 12:38

    Content type: Review

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  11. Sodium–glucose cotransporter 2 (SGLT2) inhibitors are an antihyperglycemic drug with diuretic action. We recently reported that the SGLT2 inhibitor dapagliflozin ameliorates extracellular volume expansion with...

    Authors: Ken Ohara, Takahiro Masuda, Masato Morinari, Mari Okada, Atsushi Miki, Saki Nakagawa, Takuya Murakami, Kentaro Oka, Maki Asakura, Yasuharu Miyazawa, Akito Maeshima, Tetsu Akimoto, Osamu Saito and Daisuke Nagata

    Citation: Diabetology & Metabolic Syndrome 2020 12:37

    Content type: Research

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  12. Recent studies point toward the possible regulatory roles of two lncRNAs; metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) and taurine upregulated gene 1 (TUG1) in the pathogenesis of obesity-re...

    Authors: Reyhane Ebrahimi, Karamollah Toolabi, Naghmeh Jannat Ali Pour, Samaneh Mohassel Azadi, Alireza Bahiraee, Fahimeh Zamani-Garmsiri and Solaleh Emamgholipour

    Citation: Diabetology & Metabolic Syndrome 2020 12:36

    Content type: Research

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  13. The safety of hypoglycemic drugs should be paid more attention to in elderly patients with type 2 diabetes mellitus due to their concomitant diseases, physiological decline of liver and kidney function and cog...

    Authors: Dong-Ni Yu, Lei Qiu, Shang-Yong Ning and Li-Xin Guo

    Citation: Diabetology & Metabolic Syndrome 2020 12:35

    Content type: Research

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  14. Allograft kidney transplantation has become a treatment of choice for patients with end-stage renal disease (ESRD), and post-transplant diabetes mellitus (PTDM) has been associated with impaired patient and gr...

    Authors: Hsuan Yeh, Chihung Lin, Yan-Rong Li, Chieh-Li Yen, Cheng-Chia Lee, Jung-Sheng Chen, Kuan-Hsing Chen, Ya-Chun Tian, Pi-Hua Liu and Ching-Chung Hsiao

    Citation: Diabetology & Metabolic Syndrome 2020 12:34

    Content type: Research

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  15. Diabetic nephropathy (DN) is a severe complication of diabetes with type 1 and 2. Long non-coding RNAs (lncRNAs) are being found to be involved in the DN pathogenesis. In this study, we aimed to further explor...

    Authors: Wen Zhong, Jiaoe Zeng, Junli Xue, Aimin Du and Yancheng Xu

    Citation: Diabetology & Metabolic Syndrome 2020 12:33

    Content type: Research

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  16. It is generally accepted that obesity can lead to metabolic disorders such as NAFLD and insulin resistance. However, the underlying mechanism has been poorly understood. Moreover, there is evidence to support ...

    Authors: Reza Afrisham, Sahar Sadegh-Nejadi, Reza Meshkani, Solaleh Emamgholipour and Maliheh Paknejad

    Citation: Diabetology & Metabolic Syndrome 2020 12:32

    Content type: Research

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  17. Evidence suggests that pathophysiological conditions such as obesity and type 2 diabetes (T2D) are associated with morphologic and metabolic alterations in the small intestinal mucosa. Exploring these alterati...

    Authors: Catherine Lalande, Jean-Philippe Drouin-Chartier, André J. Tremblay, Patrick Couture and Alain Veilleux

    Citation: Diabetology & Metabolic Syndrome 2020 12:31

    Content type: Research

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  18. Diabetes and diabetic complications are considered as leading causes of both morbidity and mortality in the world. Unfortunately, routine medical treatments used for affected patients possess undesirable side ...

    Authors: Mohammad Hossein Pourhanifeh, Azam Hosseinzadeh, Ehsan Dehdashtian, Karim Hemati and Saeed Mehrzadi

    Citation: Diabetology & Metabolic Syndrome 2020 12:30

    Content type: Review

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  19. Obesity and Overweight at an early age can contribute with many chronic diseases such as cancers, diabetes and cardiovascular diseases. Diet-related inflammation is one of the most important underlying mechani...

    Authors: Farhad Vahid, Fatemeh Bourbour, Maryam Gholamalizadeh, Nitin Shivappa, James R. Hébert, Khatereh Babakhani, Alireza Mosavi Jarrahi, Samaneh Mirzaei Dahka and Saeid Doaei

    Citation: Diabetology & Metabolic Syndrome 2020 12:29

    Content type: Research

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  20. Congenital generalized lipodystrophy (CGL) is a rare autosomal recessive disorder characterized by the near-total loss of subcutaneous adipose tissue soon after birth, resulting in ectopic fat deposition and s...

    Authors: Renan Magalhães Montenegro Junior, Grayce Ellen da Cruz Paiva Lima, Virgínia Oliveira Fernandes, Ana Paula Dias Rangel Montenegro, Clarisse Mourão Melo Ponte, Lívia Vasconcelos Martins, Daniel Pascoalino Pinheiro, Maria Elisabete Amaral de Moraes, Manoel Odorico de Moraes Filho and Catarina Brasil d’Alva

    Citation: Diabetology & Metabolic Syndrome 2020 12:28

    Content type: Research

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  21. This study aimed to assess the agreement and efficacy of the Ipswich Touch Test compared to the monofilament test in individuals with type 2 diabetes.

    Authors: Luz Marina Alfonso Dutra, Mirian Conceição Moura, Flaviene Alves do Prado, Giselle De Oliveira Lima, Manuela Costa Melo, Rubens Nelson Morato Fernandez and Maria Rita Carvalho Garbi Novaes

    Citation: Diabetology & Metabolic Syndrome 2020 12:27

    Content type: Research

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  22. Detecting early type 2 diabetes (T2D) risk factors may reduce or prevent the development of the disease. We conducted a pilot study to generate preliminary data on the perception of T2D and further determined ...

    Authors: Janet Antwi, Rebecca Lavin, Stacey Sullivan and Maria Bellavia

    Citation: Diabetology & Metabolic Syndrome 2020 12:25

    Content type: Research

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  23. Type 1 diabetes (T1D) affects psychologically not only the persons with diabetes themselves but affects their family members. Few studies were conducted to investigate mental health in T1D partners. This study...

    Authors: E. Buin, E. J. Pavin and M. S. V. M. Silveira

    Citation: Diabetology & Metabolic Syndrome 2020 12:23

    Content type: Research

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  24. The International Consensus in Time in Range (TIR) was recently released and defined the concept of the time spent in the target range between 70 and 180 mg/dL while reducing time in hypoglycemia, for patients...

    Authors: Monica Andrade Lima Gabbay, Melanie Rodacki, Luis Eduardo Calliari, Andre Gustavo Daher Vianna, Marcio Krakauer, Mauro Scharf Pinto, Janice Sepúlveda Reis, Marcia Puñales, Leonardo Garcia Miranda, Ana Claudia Ramalho, Denise Reis Franco and Hermelinda Pedrosa Cordeiro Pedrosa

    Citation: Diabetology & Metabolic Syndrome 2020 12:22

    Content type: Review

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  25. The use of highly active anti- retroviral therapy (HAART) as well as human immunodeficiency virus (HIV) per se have been shown to be related with diabetes among patients living with HIV. There is limited evide...

    Authors: Alemu Gebrie, Bekele Tesfaye, Tensae Gebru, Fentahun Adane, Worku Abie and Mekonnen Sisay

    Citation: Diabetology & Metabolic Syndrome 2020 12:20

    Content type: Research

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  26. Few studies examined associations between depressive symptoms and metabolic syndrome (MetS) among older Chinese adults. Considering that the prevalence of depressive symptoms is high in older Chinese adults, w...

    Authors: Jing-Hong Liu, Yu-Xi Qian, Qing-Hua Ma, Hong-Peng Sun, Yong Xu and Chen-Wei Pan

    Citation: Diabetology & Metabolic Syndrome 2020 12:18

    Content type: Research

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  27. Existing evidence suggest that low concentrations of vitamin A and E may have a contribution to the development of diabetes complications; however, data regarding the status of vitamin A and E among individual...

    Authors: Hebah Alawi Kutbi and Sahar Ali Hammouda

    Citation: Diabetology & Metabolic Syndrome 2020 12:17

    Content type: Research

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  28. Metabolic syndrome (MS) is a complex disorder represented by a set of cardiovascular risk factors usually related to central fat deposition, insulin resistance, hypertension and dyslipidemia. It is associated ...

    Authors: Ana Denise Brandão, Jeferson Hernandes da Silva, Sarah Mariane Oliveira Lima, Leiciane Lima, Bhianca Loize, Antônio Adolfo Mattos de Castro, Claudia Kümpel and Elias Ferreira Porto

    Citation: Diabetology & Metabolic Syndrome 2020 12:16

    Content type: Research

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  29. To adapt and validate the Clarke and Gold questionnaires and the Edinburgh Hypoglycemia Symptom Scale (EHSS) to Brazilian Portuguese and to determine the prevalence and risk factors associated with impaired aw...

    Authors: Paula Stefenon, André Luís Marques da Silveira, Luana Seminotti Giaretta, Cristiane Bauermann Leitão and Andrea Carla Bauer

    Citation: Diabetology & Metabolic Syndrome 2020 12:15

    Content type: Research

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  30. Obesity is associated with increased general mortality and comorbidities, it is multifactorial and some evidence has shown that sleep duration and shift work may be implicated in its pathogenesis.

    Authors: Maria Carlota Borba Brum, Fábio Fernandes Dantas Filho, Claúdia Carolina Schnorr, Otávio Azevedo Bertoletti, Gustavo Borchardt Bottega and Ticiana da Costa Rodrigues

    Citation: Diabetology & Metabolic Syndrome 2020 12:13

    Content type: Research

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  31. Human data supporting a role for endoplasmic reticulum (ER) stress and calcium dyshomeostasis in diabetes is scarce. Darier disease (DD) is a hereditary skin disease caused by mutations in the ATP2A2 gene encodin...

    Authors: Tara Ahanian, Philip Curman, Ivone U. S. Leong, Kerstin Brismar, Etty Bachar-Wikstrom, Martin Cederlöf and Jakob D. Wikstrom

    Citation: Diabetology & Metabolic Syndrome 2020 12:12

    Content type: Research

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  32. The primary objective of our study was to determine which factors influence health literacy (HL) in patients with type 1 diabetes (T1D) and type 2 diabetes (T2D), and the secondary one was to evaluate the infl...

    Authors: Marilia B. Gomes, Luiza Harcar Muniz, Laura Gomes Nunes Melo, Marcela Haas Pizarro, Bianca Senger Vasconcelos Barros, Deborah Conte Santos and Carlos Antonio Negrato

    Citation: Diabetology & Metabolic Syndrome 2020 12:11

    Content type: Research

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  33. Metabolic syndrome (MetS) has been suggested to be a risk factor for many cancers, including breast cancer. However, it remains unclear whether MetS predicts poor prognosis in women with breast cancer. A meta-...

    Authors: Peiting Li, Tianying Wang, Chen Zeng, Meng Yang, Gang Li, Jiang Han and Wei Wu

    Citation: Diabetology & Metabolic Syndrome 2020 12:10

    Content type: Research

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  34. Reduced serum level of taurine in type 2 diabetes mellitus (T2DM) was shown to be associated with the metabolic alterations and clinical complications of diabetes. Dietary supplementation with taurine may atte...

    Authors: Vahid Maleki, Reza Mahdavi, Fatemeh Hajizadeh-Sharafabad and Mohammad Alizadeh

    Citation: Diabetology & Metabolic Syndrome 2020 12:9

    Content type: Research

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  35. Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in patients with type 2 diabetes (T2DM). Carotid intima-media thickness (CIMT) is considered a preclinical stage of atherosclerosis....

    Authors: Yuan-Yuan Zhou, Hong-Mei Qiu, Ying Yang and Yuan-Yuan Han

    Citation: Diabetology & Metabolic Syndrome 2020 12:8

    Content type: Research

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  36. Serum retinol-binding protein 4 (RBP4) plays a critical role in insulin resistance. The mechanism behind the impact of laparoscopic sleeve gastrectomy (LSG) on glucose metabolism is unclear. Hence, we aimed to...

    Authors: Xingchun Wang, Yueye Huang, Jingyang Gao, Hang Sun, Muthukumaran Jayachandran and Shen Qu

    Citation: Diabetology & Metabolic Syndrome 2020 12:7

    Content type: Research

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  37. Dysglycaemia is defined by elevated glucose levels in the blood, commonly characterized by impaired fasting glucose, impaired glucose tolerance, elevated glycated haemoglobin, or diabetes mellitus (DM) diagnos...

    Authors: Camila Maciel De Oliveira, Luciane Viater Tureck, Danilo Alvares, Chunyu Liu, Andrea Roseli Vançan Russo Horimoto, Rafael de Oliveira Alvim, José Eduardo Krieger and Alexandre C. Pereira

    Citation: Diabetology & Metabolic Syndrome 2020 12:6

    Content type: Short report

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  38. Chloride is a key electrolyte that regulates the body fluid distribution. Accordingly, manipulating chloride kinetics by selecting a suitable diuretic could be an attractive strategy for correcting body fluid ...

    Authors: Hajime Kataoka and Yuichi Yoshida

    Citation: Diabetology & Metabolic Syndrome 2020 12:5

    Content type: Research

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  39. We compared the effects of sodium–glucose cotransporter 2 (SGLT2) inhibitors on renal function in participants with type 2 diabetes and chronic kidney disease (CKD) classified by degree of albuminuria.

    Authors: Akinobu Nakamura, Hideaki Miyoshi, Hiraku Kameda, Kumiko Yamashita and Yoshio Kurihara

    Citation: Diabetology & Metabolic Syndrome 2020 12:4

    Content type: Short report

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  40. New technologies are changing diabetes treatment and contributing better outcomes in developed countries. To our knowledge, no previous studies have investigated the comparative effect of sensor-based monitori...

    Authors: Luis Eduardo P. Calliari, Marcio Krakauer, Andre Gustavo Daher Vianna, Yashesvini Ram, Douglas Eugenio Barbieri, Yongjin Xu and Timothy C. Dunn

    Citation: Diabetology & Metabolic Syndrome 2020 12:3

    Content type: Research

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  41. The prevalence of metabolic syndrome varies among populations with different ethnicities. Asian populations develop metabolic complications at lower amounts of adiposity than western populations. The role of a...

    Authors: Fathimah S. Sigit, Dicky L. Tahapary, Stella Trompet, Erliyani Sartono, Ko Willems van Dijk, Frits R. Rosendaal and Renée de Mutsert

    Citation: Diabetology & Metabolic Syndrome 2020 12:2

    Content type: Research

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  42. Diabetes mellitus is an important risk factor for cardiomyopathy. Increasing oxidative stress may be one of the main factors of diabetic cardiomyopathy. A13, a newly synthesized curcumin analog, was proved to ...

    Authors: Lanting Xiang, Qiongying Zhang, Chen Chi, Gu Wu, Zhongmin Lin, Jianmin Li, Qianru Gu and Guorong Chen

    Citation: Diabetology & Metabolic Syndrome 2020 12:1

    Content type: Research

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  43. Type 2 diabetes mellitus (T2DM) and periodontitis are chronic inflammatory diseases with a bidirectional relationship. The uncontrolled levels of glucose in T2DM patients change the pathophysiology and balance...

    Authors: Juan Antonio Arreguin-Cano, Brenda Ayerdi-Nájera, Arvey Tacuba-Saavedra, Napoleón Navarro-Tito, Alfonso Dávalos-Martínez, Abel Emigdio-Vargas, Elia Barrera-Rodríguez, Nubia Blanco-García, Gloria Gutiérrez-Venegas, Elías Ventura-Molina and Gladys León-Dorantes

    Citation: Diabetology & Metabolic Syndrome 2019 11:113

    Content type: Research

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  44. This study aimed to observe the hypoglycemic effect of cassia seed extract in rats with type-2 diabetes mellitus and its effect on reducing insulin resistance in the skeletal muscle.

    Authors: Qiu-Ying Wang, Ai-Hua Tong, Ying-Ying Pan, Xian-Dang Zhang, Wen-Yu Ding and Wen Xiong

    Citation: Diabetology & Metabolic Syndrome 2019 11:108

    Content type: Research

    Published on:

  45. Evogliptin (EVO) is a potent and selective dipeptidyl peptidase-4 inhibitor (DPP4i) developed for the treatment of type 2 diabetes mellitus (T2DM). DPP4is are known to exhibit a better glucose-lowering effect ...

    Authors: Cintia Cercato, Joao Soares Felício, Luis Augusto Tavares Russo, Joao Lindolfo Cunha Borges, Joao Salles, Patricia Muskat, Teresa Bonansea, Antonio Roberto Chacra, Freddy Goldberg Eliaschewitz and Adriana Costa Forti

    Citation: Diabetology & Metabolic Syndrome 2019 11:107

    Content type: Research

    Published on:


The official journal of the Brazilian Diabetes Society.

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