The official journal of the Brazilian Diabetes Society.
Articles
Page 1 of 36
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Citation: Diabetology & Metabolic Syndrome 2023 15:117
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An early prediction model for gestational diabetes mellitus based on metabolomic biomarkers
Gestational diabetes mellitus (GDM) represents the main metabolic alteration during pregnancy. The available methods for diagnosing GDM identify women when the disease is established, and pancreatic beta-cell ...
Citation: Diabetology & Metabolic Syndrome 2023 15:116 -
Higher β cell death in pregnant women, measured by DNA methylation patterns of cell-free DNA, compared to new-onset type 1 and type 2 diabetes subjects: a cross-sectional study
Diabetes is a metabolic disorder of glucose homeostasis in which β cell destruction occurs silently and is detected mainly when symptoms appear. In the last few years, it has emerged a great interest in develo...
Citation: Diabetology & Metabolic Syndrome 2023 15:115 -
Sexual dimorphism in mitochondrial dysfunction and diabetes mellitus: evidence from a population-based cohort study
Pathophysiological mechanisms underlying sex-based differences in diabetes remain poorly understood. Mitochondrial metabolite methylmalonic acid (MMA) accumulation reflects mitochondrial dysfunction which is i...
Citation: Diabetology & Metabolic Syndrome 2023 15:114 -
Effects of SGLT-2 inhibitors on adipose tissue distribution in patients with type 2 diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials
Sodium-glucose cotransporter-2 (SGLT-2) inhibitors therapies were reported to affect adipose tissue distribution. However, the available evidence about the effect of SGLT-2 inhibitor on adipose tissue is contr...
Citation: Diabetology & Metabolic Syndrome 2023 15:113 -
Association of triglyceride-glucose index with early neurological deterioration events in patients with acute ischemic stroke
The Triglyceride and Glucose (TyG) index has been found to have a strong correlation with the recurrence of acute ischemic stroke (AIS) and poor patient outcomes. Nevertheless, the relationship between the TyG...
Citation: Diabetology & Metabolic Syndrome 2023 15:112 -
Comparison of lipid accumulation product and visceral adiposity index with traditional obesity indices in early-onset type 2 diabetes prediction: a cross-sectional study
The purpose of the study was to compare the efficacy of two novel obesity indices, lipid accumulation product (LAP) and visceral adiposity index (VAI), with traditional obesity indices in predicting early-onse...
Citation: Diabetology & Metabolic Syndrome 2023 15:111 -
Comparing angiotensin receptor–neprilysin inhibitors with sodium–glucose cotransporter 2 inhibitors for heart failure with diabetes mellitus
Clinical comparisons of angiotensin receptor–neprilysin inhibitors (ARNI) and sodium–glucose cotransporter 2 inhibitors (SGLT2i) treatment in patients with HFrEF and T2DM are limited. This study evaluated the ...
Citation: Diabetology & Metabolic Syndrome 2023 15:110 -
Retraction Note: Probiotic assisted weight management as a main factor for glycemic control in patients with type 2 diabetes: a randomized controlled trial
Citation: Diabetology & Metabolic Syndrome 2023 15:109 -
Associations of metabolic syndrome, its severity with cognitive impairment among hemodialysis patients
In the general population, metabolic syndrome (MetS) is associated with increased risk of cognitive impairment, including global and specific cognitive domains. These associations are not well studied in patie...
Citation: Diabetology & Metabolic Syndrome 2023 15:108 -
Mediterranean diet lowers all-cause and cardiovascular mortality for patients with metabolic syndrome
A Mediterranean-style diet (MED) can promote people lengthen the span of life and avoid atherosclerotic cardiovascular disease (ASCVD) in primary prevention. Metabolic syndrome (MetS) can significantly reduce ...
Citation: Diabetology & Metabolic Syndrome 2023 15:107 -
How effective are anthocyanins on healthy modification of cardiometabolic risk factors: a systematic review and meta-analysis
In this meta-analysis, findings from recent studies on the preventive properties of anthocyanins (ACN) against cardiovascular disease are summarized.
Citation: Diabetology & Metabolic Syndrome 2023 15:106 -
High-normal serum bilirubin decreased the risk of lower limb atherosclerosis in type 2 diabetes: a real-world study
Bilirubin has been found to protect against overt atherosclerotic diseases, but to date, few studies have investigated the effects of bilirubin especially within the normal range on lower limb atherosclerosis....
Citation: Diabetology & Metabolic Syndrome 2023 15:105 -
Association between glycemic status and the risk of acute pancreatitis: a nationwide population-based study
Although diabetes is reportedly associated with the occurrence of acute pancreatitis (AP), the risk of AP according to the duration and severity of diabetes is not yet clear. We aimed to investigate the risk o...
Citation: Diabetology & Metabolic Syndrome 2023 15:104 -
Gender-specific impacts of thigh skinfold thickness and grip strength for predicting osteoporosis in type 2 diabetes
Diabetes with co-existing bone fragility or osteoporosis is common in elderly patients, whereas is frequently underestimated.
Citation: Diabetology & Metabolic Syndrome 2023 15:103 -
Endocan in prediabetes, diabetes, and diabetes-related complications: a systematic review and meta-analysis
Diabetes is one of the chronic conditions with a high burden all around the world. Macrovascular and microvascular involvement are among the common mechanisms by which diabetes can impact patients’ lives. Endo...
Citation: Diabetology & Metabolic Syndrome 2023 15:102 -
The potential role of human islet amyloid polypeptide in type 2 diabetes mellitus and Alzheimer’s diseases
Human Islet amyloid polypeptide (hIAPP) from pancreatic β cells in the islet of Langerhans has different physiological functions including inhibiting the release of insulin and glucagon. Type 2 diabetes mellit...
Citation: Diabetology & Metabolic Syndrome 2023 15:101 -
Cervical and ocular vestibular evoked myogenic potentials in patients with Diabetic Peripheral Neuropathy
Diabetes causes impaired microarterial blood flow, demyelination and neuronal damage, which may lead to cochlear damage and vestibular malfunction. Vestibular evoked myogenic potentials (VEMP) is a simple, rep...
Citation: Diabetology & Metabolic Syndrome 2023 15:100 -
Correction: GCKR common functional polymorphisms are associated with metabolic syndrome and its components: a 10-year retrospective cohort study in Iranian adults
Citation: Diabetology & Metabolic Syndrome 2023 15:99 -
Obesity related to metabolic syndrome: comparison of obesity indicators in an older french population
Metabolic syndrome (MS) represents a cluster of metabolic abnormalities. Insulin resistance is a major component of the syndrome. We analyze in this study the relationship between body fat composition and MS i...
Citation: Diabetology & Metabolic Syndrome 2023 15:98 -
Beneficial effects of luseogliflozin on lipid profile and liver function in patients with type 2 diabetes mellitus (BLUE trial): a single-center, single-arm, open-label prospective study
Arteriosclerosis and non-alcoholic fatty liver disease are major complications of diabetes mellitus. Hyperglycemia, insulin resistance, obesity, and metabolic syndrome are associated with the progression of th...
Citation: Diabetology & Metabolic Syndrome 2023 15:97 -
Association between clinical use of lansoprazole and the risk of type 2 diabetes mellitus: a pharmacoepidemiological cohort study
Proton pump inhibitors (PPIs) are common and widely used for gastrointestinal-related disorders. Lansoprazole is one of PPIs with potential benefits of anti-inflammation, reduced oxidative stress, and anti-dia...
Citation: Diabetology & Metabolic Syndrome 2023 15:96 -
Glycemic dispersion: a new index for screening high glycemic variability
For patients with diabetes, high-frequency and -amplitude glycemic variability may be more harmful than continuous hyperglycemia; however, there is still a lack of screening indicators that can quickly and eas...
Citation: Diabetology & Metabolic Syndrome 2023 15:95 -
Correlation between the triglyceride-glucose index and the onset of atrial fibrillation in patients with non-alcoholic fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) is associated with atrial fibrillation (AF). Insulin resistance (IR) is the main cause of the high prevalence of AF in NAFLD patients. The triglyceride-glucose index (...
Citation: Diabetology & Metabolic Syndrome 2023 15:94 -
Empagliflozin ameliorates diabetic cardiomyopathy via regulated branched-chain amino acid metabolism and mTOR/p-ULK1 signaling pathway-mediated autophagy
Empagliflozin, a sodium–glucose co-transporter 2 inhibitor (SGLT2i), has been reported to significantly reduce the risk of heart failure in multiple clinical studies. However, the underlying mechanisms remain ...
Citation: Diabetology & Metabolic Syndrome 2023 15:93 -
Investigation of the relationship between sleep-related parameters and metabolic syndrome (MetS) among youths in the Southeast of Iran
There are few studies and inconsistent findings on the role of sleep-related parameters in the development of metabolic syndrome (MetS) among youths. In this study, we aim to investigate the relationship betwe...
Citation: Diabetology & Metabolic Syndrome 2023 15:91 -
Reclassification of type 2 diabetes to type 1 diabetes in Asturias (Spain) between 2011 and 2020
Differentiating between type 1 diabetes (T1D) and type 2 diabetes (T2D) can be difficult in adults. The aim of this study was to determine the frequency of diagnostic reclassification from T2D to T1D, the char...
Citation: Diabetology & Metabolic Syndrome 2023 15:90 -
Geriatric Nutrition Risk Index as a predictor of cardiovascular and all-cause mortality in older Americans with diabetes
Few studies have examined the relationship between malnutrition, as defined by the Geriatric Nutrition Risk Index (GNRI), and all-cause mortality and cardiovascular mortality events, particularly in persons wi...
Citation: Diabetology & Metabolic Syndrome 2023 15:89 -
Correction to: Development of models to predict 10-30-year cardiovascular disease risk using the Da Qing IGT and diabetes study
Citation: Diabetology & Metabolic Syndrome 2023 15:88 -
Finerenone attenuates myocardial apoptosis, metabolic disturbance and myocardial fibrosis in type 2 diabetes mellitus
Finerenone is a third-generation mineralocorticoid receptor antagonists, which has shown good cardiac function improvement in patients with type 2 diabetes in large-scale clinical trials. However, its specific...
Citation: Diabetology & Metabolic Syndrome 2023 15:87 -
Identification of mutations that causes glucose-6-phosphate transporter defect in tunisian patients with glycogenosis type 1b
Glycogen storage disease type 1b (GSD1b) is an autosomal recessive lysosomal storage disease caused by defective glucose-6-phosphate transporter encoded by SLC37A4 leading to the accumulation of glycogen in va...
Citation: Diabetology & Metabolic Syndrome 2023 15:86 -
Increased risk of death following recurrent ketoacidosis admissions: a Brazilian cohort study of young adults with type 1 diabetes
Recurrent DKA (rDKA) remains an acute type 1 diabetes complication even in post-insulin era. This study aimed to analyze the predictors and effects of rDKA on the mortality of patients with type 1 diabetes.
Citation: Diabetology & Metabolic Syndrome 2023 15:85 -
The role of wnt signaling in diabetes-induced osteoporosis
Osteoporosis, a chronic complication of diabetes mellitus, is characterized by a reduction in bone mass, destruction of bone microarchitecture, decreased bone strength, and increased bone fragility. Because of...
Citation: Diabetology & Metabolic Syndrome 2023 15:84 -
Autonomic neuropathic symptoms in patients with diabetes: practical tools for screening in daily routine
Diabetic autonomic neuropathy (DAN) is a frequent complication in people with diabetes whose screening is often neglected. This study aimed to evaluate DAN through practical tools in people with diabetes in a ...
Citation: Diabetology & Metabolic Syndrome 2023 15:83 -
Longitudinal associations between physical activity and five risk factors of metabolic syndrome in middle-aged adults in Germany
We examined the longitudinal association between (change in) physical activity (PA) with new onset of five risk factors of metabolic syndrome among 657 middle-aged adults (mean age 44.1 (standard deviation (SD...
Citation: Diabetology & Metabolic Syndrome 2023 15:82 -
A study of glycemic perturbations following two doses of COVID-19 vaccination for patients with diabetes: the impacts of vaccine type and anti-diabetes drugs
Glycemic monitoring has become critical during the COVID-19 pandemic because of poor prognosis in diabetes. Vaccines were key in reducing the spread of infection and disease severity but data were lacking on e...
Citation: Diabetology & Metabolic Syndrome 2023 15:81 -
Leveraging IgG N-glycosylation to infer the causality between T2D and hypertension
Observational studies demonstrated a bidirectional association between type 2 diabetes (T2D) and hypertension, whereas Mendelian randomization (MR) analyses supported the causality from T2D to hypertension but...
Citation: Diabetology & Metabolic Syndrome 2023 15:80 -
Protective and risk factors of impaired awareness of hypoglycemia in patients with type 1 diabetes: a cross-sectional analysis of baseline data from the PR-IAH study
Hypoglycemia in type 1 diabetes (T1D) is associated with mortality and morbidity, especially when awareness of hypoglycemia is impaired. This study aimed to investigate the protective and risk factors for impa...
Citation: Diabetology & Metabolic Syndrome 2023 15:79 -
Cumulative exposure to metabolic syndrome in a national population-based cohort of young adults and sex-specific risk for type 2 diabetes
Metabolic syndrome is associated with type 2 diabetes and its prevalence is increasing worldwide in young adults. We aimed to determine whether cumulative exposure to metabolic syndrome is associated with type...
Citation: Diabetology & Metabolic Syndrome 2023 15:78 -
Familial partial lipodystrophy type 2 and obesity, two adipose tissue pathologies with different inflammatory profiles
The transition to metabolically unhealthy obesity (MUO) is driven by the limited expandability of adipose tissue (AT). Familial Partial Lipodystrophy type 2 (FPLD2) is an alternative model for AT dysfunction t...
Citation: Diabetology & Metabolic Syndrome 2023 15:77 -
Effect of vitamin D supplementation on type 2 diabetes biomarkers: an umbrella of interventional meta-analyses
Vitamin D supplementation exerts several supporting effects on improving glycemic status, however, results are inconclusive. Thus, in the present study, we aimed to conduct an umbrella of meta-analysis regardi...
Citation: Diabetology & Metabolic Syndrome 2023 15:76 -
Optimal statin use for prevention of sepsis in type 2 diabetes mellitus
To investigate the dose-dependent protective effects of statins, specific classes of statins, and different intensities of statin use on sepsis risk in patients with type 2 diabetes mellitus (T2DM).
Citation: Diabetology & Metabolic Syndrome 2023 15:75 -
Retraction Note: The best drug supplement for obesitytreatment: a systematic review and network meta-analysis
Citation: Diabetology & Metabolic Syndrome 2023 15:74 -
The hypertension and hyperlipidemia status among type 2 diabetic patients in the community and influencing factors analysis of glycemic control
To understand the prevalence of hypertension and hyperlipidaemia as well as the current status of glycaemic control and its influencing factors among type 2 diabetes mellitus patients in the community in South...
Citation: Diabetology & Metabolic Syndrome 2023 15:73 -
Diabetes mellitus status modifies the association between N-terminal B-type natriuretic peptide and all-cause mortality risk in ischemic heart failure: a prospective cohort study
N-terminal B-type natriuretic peptide (NT-proBNP) discriminates mortality risk in diabetes mellitus (DM) and in heart failure (HF) populations. Whether DM status modifies the association between NT-proBNP and ...
Citation: Diabetology & Metabolic Syndrome 2023 15:72 -
Probiotics for glycemic and lipid profile control of the pre-diabetic patients: a randomized, double-blinded, placebo-controlled clinical trial study
Pre-diabetes is a condition in which blood glucose levels are high but not as high as in diabetic patients. However, it can lead to diabetes, making it a serious global health issue. Previous studies have show...
Citation: Diabetology & Metabolic Syndrome 2023 15:71 -
Substituting device-measured sedentary time with alternative 24-hour movement behaviours: compositional associations with adiposity and cardiometabolic risk in the ORISCAV-LUX 2 study
There is a considerable burden of sedentary time in European adults. We aimed to quantify the differences in adiposity and cardiometabolic health associated with theoretically exchanging sedentary time for alt...
Citation: Diabetology & Metabolic Syndrome 2023 15:70 -
Cardiometabolic risk indicators in individuals with bipolar disorders: a replication study
We recently conducted the first longitudinal study comparing cardiometabolic risk indicators (CMRIs) between a cohort of individuals with bipolar disorders (BDs) and controls from the general population. Here,...
Citation: Diabetology & Metabolic Syndrome 2023 15:69 -
Does hyperglycemia affect arginine metabolites in critically ill patients? A prospective cohort and in vitro study
Changes in the arginine metabolites asymmetric dimethyl-L-arginine (ADMA) and L-homoarginine and acute blood glucose concentrations have been shown to cause endothelial dysfunction and be independently associa...
Citation: Diabetology & Metabolic Syndrome 2023 15:68 -
The impact of insulin resistance on the association between metabolic syndrome and lung function: the Kangbuk Samsung Health Study
Metabolic syndrome (MS) is related to lung dysfunction. However, its impact according to insulin resistance (IR) remains unknown. Therefore, we evaluated whether the relation of MS with lung dysfunction differ...
Citation: Diabetology & Metabolic Syndrome 2023 15:65
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