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  1. Our understanding of the pathophysiology of the COVID-19 manifestations and evolution has improved over the past 10 months, but the reasons why evolution is more severe in obese and diabetic patients are not y...

    Authors: Andrey Santos, Daniéla Oliveira Magro, Rosana Evangelista-Poderoso and Mario José Abdalla Saad

    Citation: Diabetology & Metabolic Syndrome 2021 13:23

    Content type: Review

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  2. The aim of the study was to evaluate the ultrasound-derived measurements of the fetal soft-tissue, heart, liver and umbilical cord in pregnancies complicated by gestational (GDM) and type 1 diabetes mellitus (...

    Authors: Paweł Jan Stanirowski, Agata Majewska, Michał Lipa, Dorota Bomba-Opoń and Mirosław Wielgoś

    Citation: Diabetology & Metabolic Syndrome 2021 13:22

    Content type: Research

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  3. Diabetic encephalopathy is a severe diabetes complication with cognitive dysfunction and neuropsychiatric disability. The mechanisms underlying diabetic encephalopathy is believed to be relevant with oxidative...

    Authors: Chengfeng Miao, Hanbin Chen, Yulian Li, Ying Guo, Feifei Xu, Qi Chen, Yanyan Zhang, Mengjun Hu and Guorong Chen

    Citation: Diabetology & Metabolic Syndrome 2021 13:21

    Content type: Research

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  4. Previous studies reported that common functional variants (rs780093, rs780094, and rs1260326) in the glucokinase regulator gene (GCKR) were associated with metabolic syndrome despite the simultaneous association ...

    Authors: Asiyeh Sadat Zahedi, Mahdi Akbarzadeh, Bahareh Sedaghati-Khayat, Atefeh Seyedhamzehzadeh and Maryam S. Daneshpour

    Citation: Diabetology & Metabolic Syndrome 2021 13:20

    Content type: Research

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  5. Bariatric surgery, especially Roux-en-Y gastric bypass (RYGB), is the most effective and durable treatment option for severe obesity. The mechanisms involving adipose tissue may be important to explain the eff...

    Authors: Rafael Ferraz-Bannitz, Caroline Rossi Welendorf, Priscila Oliveira Coelho, Wilson Salgado Jr, Carla Barbosa Nonino, Rebeca A. Beraldo and Maria Cristina Foss-Freitas

    Citation: Diabetology & Metabolic Syndrome 2021 13:19

    Content type: Research

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  6. Polycystic ovary syndrome (PCOS) is a common endocrine disease affecting women of reproductive age and associated with reproductive and metabolic dysfunction. Few studies are available regarding metabolic trai...

    Authors: Poli Mara Spritzer, Ramon Bossardi Ramos, Lucas Bandeira Marchesan, Monica de Oliveira and Enrico Carmina

    Citation: Diabetology & Metabolic Syndrome 2021 13:18

    Content type: Research

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  7. Glucagon-like peptide-1 receptor (GLP-1R) activation may improve myocardial performance in the context of ischaemia, independent of glycaemic control, in individuals with and without type 2 diabetes mellitus.

    Authors: Aung Myat, Simon R. Redwood, Satpal Arri, Bernard J. Gersh, Deepak L. Bhatt and Michael S. Marber

    Citation: Diabetology & Metabolic Syndrome 2021 13:17

    Content type: Research

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  8. The beneficial effects of polyphenols have been reported. This study aimed to investigate the effect of oral Ellagic acid (EA) supplement on insulin resistance (IR) and Fetuin-A and serum sirtuin1 (SIRT1) in t...

    Authors: Mahnaz Ghadimi, Farshad Foroughi, Sima Hashemipour, Mohammadreza Rashidi Nooshabadi, Mohammad Hossein Ahmadi, Mojtaba Ghadimi Yari, Maria Kavianpour and Hossein Khadem Haghighian

    Citation: Diabetology & Metabolic Syndrome 2021 13:16

    Content type: Research

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  9. Hypertriglyceridemia (HTG) is considered an independent risk factor for major adverse cardiovascular events (MACE).

    Authors: Yan-yan Qi, Li Yan, Zhong-min Wang, Xi Wang, Hua Meng, Wen-bo Li, Dong-chang Chen, Meng Li, Jun Liu and Song-tao An

    Citation: Diabetology & Metabolic Syndrome 2021 13:15

    Content type: Research

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  10. There is growing evidence that the C1qTNF-related protein (CTRP) family has a crucial role in the pathophysiology of metabolic disorders such as type 2 diabetes (T2D) and obesity. We sought to identify the ass...

    Authors: Ziba Majidi, Solaleh Emamgholipour, Abolfazl Omidifar, Soheil Rahmani Fard, Hossein Poustchi and Mehrnoosh Shanaki

    Citation: Diabetology & Metabolic Syndrome 2021 13:14

    Content type: Research

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  11. Type 2 diabetes is a common non-communicable disease that is responsible for about 9% of all deaths and a 25% reduction in life expectancy. However, nearly half of the diabetic patients are not aware of their ...

    Authors: Fateme Kianpour, Mohammad Fararouei, Jafar Hassanzadeh, Mohammadnabi Mohammadi and Mostafa Dianatinasab

    Citation: Diabetology & Metabolic Syndrome 2021 13:13

    Content type: Research

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  12. Insulin-related disorders, including insulin resistance, insulin insensitivity, and insulinemia, is considered early predictors of major chronic disease risk. Using a set of correlated nutrient as nutrient pat...

    Authors: Farshad Teymoori, Ebrahim Mokhtari, Pantea Salehi, Firoozeh Hosseini-Esfahani, Parvin Mirmiran and Fereidoun Azizi

    Citation: Diabetology & Metabolic Syndrome 2021 13:12

    Content type: Research

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  13. The daily peak in dopaminergic neuronal activity at the area of the biological clock (hypothalamic suprachiasmatic nuclei [SCN]) is diminished in obese/insulin resistant vs lean/insulin sensitive animals. The ...

    Authors: Shuqin Luo, Michael Ezrokhi, Nicholas Cominos, Tsung-Huang Tsai, Carl R. Stoelzel, Yelena Trubitsyna and Anthony H. Cincotta

    Citation: Diabetology & Metabolic Syndrome 2021 13:11

    Content type: Research

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  14. Obesity and Metabolic Syndrome have been associated with cardiovascular, diabetes and cancer incidence. Obesity is a state of inflammation. There are cross-talks between adipocyte, adipokines, pro-inflammatory...

    Authors: Kartika W. Taroeno-Hariadi, Mardiah S. Hardianti, Hemi Sinorita and Teguh Aryandono

    Citation: Diabetology & Metabolic Syndrome 2021 13:10

    Content type: Review

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  15. Endotrophin is one of the extracellular matrix proteins secreted by adipose tissue. In this study, we aimed to investigate the effects of changes in blood glucose levels on serum endotrophin levels secreted by...

    Authors: Sengul Aydin Yoldemir, Yucel Arman, Murat Akarsu, Ozgur Altun, Mustafa Ozcan and Tufan Tukek

    Citation: Diabetology & Metabolic Syndrome 2021 13:9

    Content type: Research

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  16. Sepsis is life-threatening disease with systemic inflammation and can lead to various diseases, including septic acute kidney injury (AKI). Recently, diverse circular RNAs (circRNAs) are considered to be invol...

    Authors: Heyun Li, Xia Zhang, Peng Wang, Xiaoyan Zhou, Haiying Liang and Caoni Li

    Citation: Diabetology & Metabolic Syndrome 2021 13:7

    Content type: Research

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  17. Diabetes mellitus (DM) could be classified as type 1 diabetes mellitus (T1DM), type 2 diabetes mellitus (T2DM), gestational diabetes mellitus (GDM) and others according to etiology and pathology. Diabetic neph...

    Authors: Wanwan Luo, Lingmin Zhang, Lingling Sheng, Zhencheng Zhang and Zaixing Yang

    Citation: Diabetology & Metabolic Syndrome 2021 13:6

    Content type: Research

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  18. A dysregulated host immune response is common in patients with COVID-19.

    Authors: Dafeng Liu, Yong Wang, Bennan Zhao, Lijuan Lan, Yaling Liu, Lei Bao, Hong Chen, Min Yang, Qingfeng Li and Yilan Zeng

    Citation: Diabetology & Metabolic Syndrome 2021 13:5

    Content type: Research

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  19. Metabolic syndrome is a cluster of conditions that occur together, increasing the risk of cardiovascular disease. However, the relationship between metabolic syndrome and dementia has remained controversial. U...

    Authors: Yeo Jin Kim, Sang Mi Kim, Dae Hyun Jeong, Sang-Kyu Lee, Moo-Eob Ahn and Ohk-Hyun Ryu

    Citation: Diabetology & Metabolic Syndrome 2021 13:4

    Content type: Research

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  20. Regarding the increasing prevalence of cardiometabolic abnormalities, and its association with non-communicable chronic diseases, providing preventive and therapeutic strategies is a priority. A randomized pla...

    Authors: Zahra Yari, Zahra Naser-Nakhaee, Elahe Karimi‐Shahrbabak, Makan Cheraghpour, Mehdi Hedayati, Seyede Marjan Mohaghegh, Shahrzad Ommi and Azita Hekmatdoost

    Citation: Diabetology & Metabolic Syndrome 2021 13:3

    Content type: Research

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  21. This manuscript reports the Brazilian Diabetes Society Position Statement for insulin adjustments based on trend arrows observed in continuous glucose monitoring systems. The Brazilian Diabetes Society support...

    Authors: M. Rodacki, L. E. Calliari, A. C. Ramalho, A. G. D. Vianna, D. R. Franco, K. F. S. Melo, L. R. Araujo, M. Krakauer, M. Scharf, W. Minicucci, R. Ziegler and M. Gabbay

    Citation: Diabetology & Metabolic Syndrome 2021 13:2

    Content type: Commentary

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  22. To investigate the association of youth metabolic syndrome (MetS) and its components, individually and in combination with early adulthood incident type 2 diabetes (T2DM).

    Authors: Golaleh Asghari, Mitra Hasheminia, Abolfazl Heidari, Parvin Mirmiran, Kamran Guity, Mohammad Karim Shahrzad, Fereidoun Azizi and Farzad Hadaegh

    Citation: Diabetology & Metabolic Syndrome 2021 13:1

    Content type: Research

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  23. Long non-coding RNA cyclin-dependent kinase inhibitor 2B antisense RNA 1 (CDKN2B-AS1) has been reported to be related to diabetic nephropathy (DN) progression. However, the regulatory mechanisms of CDKN2B-AS1 ...

    Authors: Jing Chang, Yanming Yu, Zhan Fang, Haiyan He, Dan Wang, Jian Teng and Lina Yang

    Citation: Diabetology & Metabolic Syndrome 2020 12:109

    Content type: Research

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  24. To examine the association of dietary behaviors, lifestyle, and biochemical factors with metabolic phenotypes of obesity among obese Iranian children and adolescents.

    Authors: Mostafa Qorbani, Pouria Khashayar, Hadith Rastad, Hanieh-Sadat Ejtahed, Ehsan Shahrestanaki, Ehsan Seif, Seyede Shahrbanoo Daniali, Masoomeh Goudarzi, Mohammad Esmaeil Motlagh, Zeinab Khodaparast, Ramin Heshmat and Roya Kelishadi

    Citation: Diabetology & Metabolic Syndrome 2020 12:108

    Content type: Research

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  25. Adult-onset autoimmune diabetes (AID) has two different phenotypes: classic type 1 diabetes mellitus (T1DM), with insulin requirement just after diagnosis, and latent autoimmune diabetes in adults (LADA). The ...

    Authors: Lúcia Fadiga, Joana Saraiva, Diana Catarino, João Frade, Miguel Melo and Isabel Paiva

    Citation: Diabetology & Metabolic Syndrome 2020 12:107

    Content type: Research

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  26. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Zahra Aslani, Omid Sadeghi, Motahar Heidari-Beni, Hoda Zahedi, Fereshteh Baygi, Nitin Shivappa, James R. Hébert, Sajjad Moradi, Gity Sotoudeh, Hamid Asayesh, Shirin Djalalinia and Mostafa Qorbani

    Citation: Diabetology & Metabolic Syndrome 2020 12:106

    Content type: Correction

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    The original article was published in Diabetology & Metabolic Syndrome 2020 12:86

  27. Aim of this study is to investigate a possible association of hypoglycemic episodes and arterial hypertension. We hypothesize that hospitalized insulin-treated diabetes patients with hypertensive crisis have m...

    Authors: Abimbola Abobarin-Adeagbo, Andreas Wienke, Matthias Girndt and Rainer U. Pliquett

    Citation: Diabetology & Metabolic Syndrome 2020 12:104

    Content type: Research

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  28. Diabetes mellitus (DM) is associated with adverse outcomes, and visceral adipose tissue (VAT), classified into intraperitoneal VAT (IVAT) and retroperitoneal VAT (RVAT), is associated with insulin resistance. ...

    Authors: Muhei Tanaka, Hiroshi Okada, Yoshitaka Hashimoto, Muneaki Kumagai, Hiromi Nishimura and Michiaki Fukui

    Citation: Diabetology & Metabolic Syndrome 2020 12:103

    Content type: Research

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  29. Long QT interval (QT) and abnormal QT dispersion (QTd) are associated with sudden death. The relationship between cardiac autonomic neuropathy (CAN) and QT indices in type 2 diabetic patients were investigated.

    Authors: Maryam Vasheghani, Farzaneh Sarvghadi, Mohammad Reza Beyranvand and Habib Emami

    Citation: Diabetology & Metabolic Syndrome 2020 12:102

    Content type: Research

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  30. There is a lack of studies examining the association between Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) and metabolic syndrome (MetS) and obesity. Thus, this study aimed to investigate ...

    Authors: Saba Mohammadpour, Parivash Ghorbaninejad, Nasim Janbozorgi and Sakineh Shab-Bidar

    Citation: Diabetology & Metabolic Syndrome 2020 12:101

    Content type: Research

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  31. Multiple epidemiological studies were conducted amongst a variety of ethnic groups and showed discrepancies in the prevalence of metabolic syndrome (MeS) and its individual components. This study aimed to dete...

    Authors: Kamel Ajlouni, Yousef Khader, Mohamad Alyousfi, Mohannad Al Nsour, Anwar Batieha and Hashem Jaddou

    Citation: Diabetology & Metabolic Syndrome 2020 12:100

    Content type: Research

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  32. A low-grade inflammation is associated with cardiac autonomic neuropathy (CAN) and increased concentration of leukotriene B4 (LTB4) was found in individuals with type 1 diabetes and definitive CAN. This cross-...

    Authors: Jose Antonio Januario Neves, Mozânia Reis De Matos, Theresa Ramalho, Daniele Pereira Santos-Bezerra, Cristiane Das Graças Dias Cavalcante, Renata D’ Alpino Peixoto, Márcia Silva Queiroz, Sonia Jancar and Maria Lucia Correa-Giannella

    Citation: Diabetology & Metabolic Syndrome 2020 12:99

    Content type: Short report

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  33. Research on intestinal microbiota has grown considerably, as well as the interest on probiotics’ supplementation effects on metabolism. Considering high prevalence rates of metabolic diseases linked by insulin...

    Authors: Bárbara Izabel Moraes Salles, Débora Cioffi and Sandra Roberta G. Ferreira

    Citation: Diabetology & Metabolic Syndrome 2020 12:98

    Content type: Review

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  34. Type 2 diabetes mellitus (T2DM) is a complex polygenic metabolic disease characterized by elevated blood glucose. Multiple environmental and genetic factors can increase the risk of T2DM and its complications,...

    Authors: Cuilin Li, Yuping Yang, Xin Liu, Zhongyu Li, Hong Liu and Qiuhong Tan

    Citation: Diabetology & Metabolic Syndrome 2020 12:97

    Content type: Review

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  35. Cardiovascular disease is the cause of more than 50% of mortalities globally, and this rate has grown by 8.6% since the 60 s. One of the risk factors associated with cardiovascular disease and its resulting mo...

    Authors: Nader Salari, Peyman Kaikhosro Doulatyari, Alireza Daneshkhah, Aliakbar Vaisi-Raygani, Rostam Jalali, Parnian kord Jamshidi, Alireza Abdi, Masoud Mohammadi and Mohsen Kazeminia

    Citation: Diabetology & Metabolic Syndrome 2020 12:96

    Content type: Research

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  36. Metabolic syndrome (MetS) has been related to the pathogenesis of variety categories of cancers. This meta-analysis aimed to determine the association between MetS and the incidence of lung cancer.

    Authors: Li Qiao, Deliang Ma, Hui Lv, Ding Shi, Min Fei, Yu Chen, Fei Xie, Zhuoyan Wang, Ying Wang, Wanhua Liang and Peiying Hu

    Citation: Diabetology & Metabolic Syndrome 2020 12:95

    Content type: Research

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  37. Female sexual dysfunction (FSD) is one of the chronic complications of diabetes as is male sexual dysfunction, but the former is less studied. Therefore, the aim of this study was to assess of the prevalence a...

    Authors: Adriana Gherbon, Mirela Frandes, Deiana Roman, Diana Anastasiu-Popov and Romulus Timar

    Citation: Diabetology & Metabolic Syndrome 2020 12:94

    Content type: Research

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  38. Metabolic syndrome (MetS) is a clustering of cardiovascular risk factors, which is rising in the low and middle income countries (LMICs). There are various studies with inconsistent findings that are inconclus...

    Authors: Zebenay Workneh Bitew, Ayinalem Alemu, Ermias Getaneh Ayele, Zelalem Tenaw, Anmut Alebel and Teshager Worku

    Citation: Diabetology & Metabolic Syndrome 2020 12:93

    Content type: Research

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  39. We aimed to evaluate the effects of short-term therapy with dapagliflozin on serum uric acid (SUA) and urinary uric acid (UUA) levels in patients with type 2 diabetes.

    Authors: Tao Yuan, Shixuan Liu, Yingyue Dong, Yong Fu, Yan Tang and Weigang Zhao

    Citation: Diabetology & Metabolic Syndrome 2020 12:92

    Content type: Research

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  40. People with obesity have a compromised browning capacity of adipose tissue when faced with sympathetic stimuli. This study aimed to determine whether norepinephrine treatment can enhance the induction of precu...

    Authors: Yao Qiu, Lizhi Sun, Xiaolin Hu, Xin Zhao, Hongyan Shi, Zhao Liu and Xiao Yin

    Citation: Diabetology & Metabolic Syndrome 2020 12:91

    Content type: Research

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  41. To examine the effects of gastric bypass surgery on health-related quality of life (HRQoL) in obese patients with type 2 diabetes, and to investigate their experiences of life adjustments using quantitative an...

    Authors: Petros Katsogiannos, Eva Randell, Magnus Sundbom, Andreas Rosenblad, Jan W. Eriksson and Janeth Leksell

    Citation: Diabetology & Metabolic Syndrome 2020 12:90

    Content type: Research

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  42. Brazil is one of top 10 countries with the highest number of people with diabetes mellitus (DM), affecting 16.8 million peoples. It is estimated that 7.7 million people (20–79 years) in the country have not ye...

    Authors: Cassyano J. Correr, Wendel Coura-Vital, Josélia C. Q. P. Frade, Renata C. R. M. Nascimento, Lúbia G. Nascimento, Eliete B. Pinheiro, Wesley M. Ferreira, Janice S. Reis, Karla F. S. Melo, Roberto Pontarolo, Mônica S. A. Lenzi, José V. Almeida, Hermelinda C. Pedrosa and Walter S. J. João

    Citation: Diabetology & Metabolic Syndrome 2020 12:89

    Content type: Research

    Published on:

  43. The influence of pre-pregnancy body mass index (BMI) and gestational weight gain (GWG) on perinatal outcomes of women with polycystic ovary syndrome (PCOS) remains unclear. Therefore, we explored how the above...

    Authors: Lirui Zhang, Wei Zheng, Cheng Liu, Xin Liang, Li Zhang, Zhihong Tian and Guanghui Li

    Citation: Diabetology & Metabolic Syndrome 2020 12:88

    Content type: Research

    Published on:

  44. The association of dietary inflammatory index (DII®), as an index of inflammatory quality of diet, with cardiometabolic diseases (CMDs) and risk factors (CMRFs) has been inconsistent in previous studies.

    Authors: Zahra Aslani, Omid Sadeghi, Motahar Heidari-Beni, Hoda Zahedi, Fereshteh Baygi, Nitin Shivappa, James R. Hébert, Sajjad Moradi, Gity Sotoudeh, Hamid Asayesh, Shirin Djalalinia and Mostafa Qorbani

    Citation: Diabetology & Metabolic Syndrome 2020 12:86

    Content type: Review

    Published on:

    The Correction to this article has been published in Diabetology & Metabolic Syndrome 2020 12:106

  45. HbA1c variability has been linked to retinopathy, renal disease and autonomic neuropathy in patients with type 1 diabetes mellitus (T1D) and type 2 diabetes mellitus (T2D). Although the same relationship has b...

    Authors: M. V. Pinto, L. C. G. F. Rosa, L. F. Pinto, J. R. Dantas, G. F. Salles, L. Zajdenverg, M. Rodacki and M. A. Lima

    Citation: Diabetology & Metabolic Syndrome 2020 12:85

    Content type: Short report

    Published on:

  46. Risk scores were mainly proved to predict undiagnosed type 2 diabetes mellitus (UT2DM) in a non-invasive manner and to guide earlier clinical treatment. The objective of the present study was to assess the per...

    Authors: Maher Abdallah, Safa Sharbaji, Marwa Sharbaji, Zeina Daher, Tarek Faour, Zeinab Mansour and Mohammad Hneino

    Citation: Diabetology & Metabolic Syndrome 2020 12:84

    Content type: Research

    Published on:

  47. Insulin resistance can occur in all metabolic organs including the liver, adipose tissue, and skeletal muscles. Circulating soluble epidermal growth factor receptor (soluble EGFR) and adipsin levels are altere...

    Authors: Mayu Kyohara, Jun Shirakawa, Tomoko Okuyama, Yu Togashi, Ryota Inoue, Jinghe Li, Daisuke Miyashita and Yasuo Terauchi

    Citation: Diabetology & Metabolic Syndrome 2020 12:83

    Content type: Research

    Published on:


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