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  3. Preclinical experiments on large animals are indispensable for evaluating the effectiveness of diabetes therapies. Miniature swine are well suited for such studies due to their physiological and pathophysiolog...

    Authors: Armin Strauss, Vasily Moskalenko, Christian Tiurbe, Irina Chodnevskaja, Stephan Timm, Verena A Wiegering, Christoph-Thomas Germer and Karin Ulrichs
    Citation: Diabetology & Metabolic Syndrome 2012 4:7
    Content type: Research Published on:

  4. Sleep-disordered breathing (SDB), especially obstructive sleep apnea (OSA), has frequent complications include hypertension, dyslipidemia and insulin resistance based on abdominal obesity or excess visceral fa...

    Authors: Tomoko Nakanishi-Minami, Ken Kishida, Yasuhiko Nakagawa, Munetaka Nishio, Chisa Nakagawa, Yoshiharu Nishida, Koji Yanagi, Ryoko Yoshida, Tohru Funahashi and Iichiro Shimomura
    Citation: Diabetology & Metabolic Syndrome 2012 4:6
    Content type: Short report Published on:

  5. This study aimed to examine the effects of intermittent and continuous swimming training on muscle protein metabolism in neonatal alloxan-administered rats.

    Authors: Carla Ribeiro, Lucieli T Cambri, Rodrigo A Dalia, Michel B Araújo, Ana C Ghezzi, Leandro P Moura, Gustavo G Araújo, Jose D Botezelli and Maria AR Mello
    Citation: Diabetology & Metabolic Syndrome 2012 4:5
    Content type: Research Published on:

  6. Plasma adiponectin is a significant correlate of the pro-inflammatory cardiometabolic risk profile associated with obesity and type 2 diabetes. Salivary pH is influenced by several cardiometabolic risk compone...

    Authors: Monique Tremblay, Yacine Loucif, Julie Methot, Diane Brisson and Daniel Gaudet
    Citation: Diabetology & Metabolic Syndrome 2012 4:4
    Content type: Research Published on:

  7. Hyperuricemia is associated with obesity. The visceral adiposity and subcutaneous adiposity may be associated with the differential metabolic risk, and the distribution of abdominal adipose tissue was signific...

    Authors: Tae Ho Kim, Seong Su Lee, Ji Han Yoo, Sung Rae Kim, Soon Jib Yoo, Ho Cheol Song, Yong-Soo Kim, Euy Jin Choi and Yong Kyun Kim
    Citation: Diabetology & Metabolic Syndrome 2012 4:3
    Content type: Research Published on:

  8. Erectile dysfunction is a common problem in type 2 diabetic patients who are at higher risk of cerebrovascular events, and it's recorded with sildenafil, a drug which is primarily used for erectile dysfunction.

    Authors: Fadhil G Al-Amran, Akeel AMH Zwain, Najah R Hadi and Ahmed M Al-Mudhaffer
    Citation: Diabetology & Metabolic Syndrome 2012 4:2
    Content type: Research Published on:

  9. We aim to investigate the effectiveness of a 10-week lifestyle intervention focusing on physical activity and high fiber intake for reducing indicators for metabolic syndrome in overweight-obese individuals. A...

    Authors: Marita S Mecca, Fernando Moreto, Franz HP Burini, Reinaldo C Dalanesi, Kátia CP McLellan and Roberto C Burini
    Citation: Diabetology & Metabolic Syndrome 2012 4:1
    Content type: Research Published on:

  11. A new simple technique based on iontophoresis technology (EZSCAN, Impeto Medical, Paris, France) has recently been developed for the screening of diabetes. In the present study, we investigated the accuracy of...

    Authors: Chang-Sheng Sheng, Wei-Fang Zeng, Qi-Fang Huang, Jean-Paul Deslypere, Yan Li and Ji-Guang Wang
    Citation: Diabetology & Metabolic Syndrome 2011 3:36
    Content type: Research Published on:

  12. An increase in the prevalence of obesity entails great expenditure for governments. Physical exercise is a powerful tool in the combat against obesity and obesity-associated diseases. This study sought to dete...

    Authors: José D Botezelli, Lucieli T Cambri, Ana C Ghezzi, Rodrigo A Dalia, Pedro P M Scariot, Carla Ribeiro, Fabrício A Voltarelli and Maria AR Mello
    Citation: Diabetology & Metabolic Syndrome 2011 3:35
    Content type: Research Published on:

  13. Adverse effects of high-fat diets (HFD) on metabolic homeostasis are linked to adipose tissue dysfunction. The goal of this study was to examine the effect of the HFD nature on adipose tissue activity, metabol...

    Authors: Souhad El Akoum, Vikie Lamontagne, Isabelle Cloutier and Jean-François Tanguay
    Citation: Diabetology & Metabolic Syndrome 2011 3:34
    Content type: Research Published on:

  15. FOXC2 has lately been implicated in diabetes and obesity as well as mitochondrial function and biogenesis and also as a regulator of mtTFA/Tfam. In this study, the expression of FOXC2 and selected genes involv...

    Authors: Joakim Håkansson, Björn Eliasson, Ulf Smith and Sven Enerbäck
    Citation: Diabetology & Metabolic Syndrome 2011 3:32
    Content type: Research Published on:

  16. There are an increasing number of patients suffering from fatty liver caused by type 2 diabetes. We intended to study the preventive and therapeutic effect of L-carnitine (LC) on nonalcoholic fatty liver disea...

    Authors: Yunqiu Xia, Qing Li, Weizhen Zhong, Jing Dong, Zhulin Wang and Chunbo Wang
    Citation: Diabetology & Metabolic Syndrome 2011 3:31
    Content type: Research Published on:

  17. Prevalence of men with cardiometabolic risk factors (CMRF) is increasing in Japan. Few studies have comprehensively examined the relation between lifestyles and CMRF.

    Authors: Sayuri Katano, Yasuyuki Nakamura, Nagako Okuda, Yoshitaka Murakami, Nagako Chiba, Katsushi Yoshita, Taichiro Tanaka, Junko Tamaki, Toru Takebayashi, Akira Okayama, Katsuyuki Miura, Tomonori Okamura and Hirotsugu Ueshima
    Citation: Diabetology & Metabolic Syndrome 2011 3:30
    Content type: Research Published on:

  19. Higher serological prevalence rates of helicobacter pylori (H. pylori) infection have been reported in patients with type 1 diabetes (T1DM) and autoimmune thyroiditis (AT). Patients with T1DM are at increased ...

    Authors: Mervat M El-Eshmawy, Amany K El-Hawary, Soma S Abdel Gawad and Azza A El-Baiomy
    Citation: Diabetology & Metabolic Syndrome 2011 3:28
    Content type: Research Published on:

  20. MicroRNAs (miRNAs) are a newly discovered type of small non-protein coding RNA that function in the inhibition of effective mRNA translation, and may serve as susceptibility genes for various disease developme...

    Authors: Xiaofan Mi, Hongzhi He, Yangxin Deng, Abert M Levin, Jin-Xiong She, Qing-Sheng Mi and Li Zhou
    Citation: Diabetology & Metabolic Syndrome 2011 3:27
    Content type: Letter to the Editor Published on:

  21. Comorbid depression in diabetes has been suggested as one of the possible causes of an inadequate glycemic control. The purpose of this study was to investigate the association between major depression and the...

    Authors: Marcelo Papelbaum, Rodrigo O Moreira, Walmir Coutinho, Rosane Kupfer, Leão Zagury, Silvia Freitas and José C Appolinário
    Citation: Diabetology & Metabolic Syndrome 2011 3:26
    Content type: Research Published on:

  23. C-reactive protein (CRP) is positively associated with risk for cardiovascular disease and all-cause mortality. Some but not all randomized and non-randomized clinical trials found significant associations bet...

    Authors: Jiatao Ye, James N Kiage, Donna K Arnett, Alfred A Bartolucci and Edmond K Kabagambe
    Citation: Diabetology & Metabolic Syndrome 2011 3:24
    Content type: Research Published on:

  25. Although it is well known in the literature that high triglyceride serum (TG) levels can jeopardize the metabolic control, little is known about the influence of low TG on type 1 diabetes patients (T1D). The a...

    Authors: Leticia M Alcantara, Nathalia E Silveira, Joana R Dantas, Paula B Araujo, Marcus M de Oliveira, Adolpho Milech, Lenita Zajdenverg, Melanie Rodacki and José EP de Oliveira
    Citation: Diabetology & Metabolic Syndrome 2011 3:22
    Content type: Short report Published on:

  26. The presence of microalbuminuria can be associated with overt nephropathy and cardiovascular disease in patients with type 1 diabetes (T1D). We aimed to determine the incidence and evaluate the baseline predic...

    Authors: Roberta A Cobas, Bráulio Santos, Pedro CB da Silva, Ricardo Neves and Marilia B Gomes
    Citation: Diabetology & Metabolic Syndrome 2011 3:21
    Content type: Research Published on:

  27. The purpose of this study was to evaluate the effects of cigarette smoke exposure before pregnancy on diabetic rats and their offspring development.

    Authors: Débora C Damasceno, Yuri K Sinzato, Paula H Lima, Maricelma S de Souza, Kleber E Campos, Bruna Dallaqua, Iracema M Calderon, Marilza V Rudge and Gustavo T Volpato
    Citation: Diabetology & Metabolic Syndrome 2011 3:20
    Content type: Research Published on:

  28. To investigate and compare the incidence of histopathological placental lesions in mild gestational hyperglycemia, gestational diabetes and overt diabetes at term and preterm gestation.

    Authors: Marilza VC Rudge, César P Lima, Débora C Damasceno, Yuri K Sinzato, Gustavo Napoli, Cibele VC Rudge, Franciane Q Gallego and Iracema MP Calderon
    Citation: Diabetology & Metabolic Syndrome 2011 3:19
    Content type: Research Published on:

  29. Although the positive relationship between insulin resistance (IR) and central obesity is well known, the direct relationship between waist circumference and IR is not clear yet and there is no consensus regar...

    Authors: Azita Zadeh-Vakili, Fahimeh Ramezani Tehrani and Farhad Hosseinpanah
    Citation: Diabetology & Metabolic Syndrome 2011 3:18
    Content type: Research Published on:

  31. Adipokines, e.g. TNFα, IL-6 and leptin increase insulin resistance, and consequent hyperinsulinaemia influences breast cancer progression. Beside its mitogenic effects, insulin may influence adipokine producti...

    Authors: Jean Grisouard, Kaethi Dembinski, Doris Mayer, Ulrich Keller, Beat Müller and Mirjam Christ-Crain
    Citation: Diabetology & Metabolic Syndrome 2011 3:16
    Content type: Short report Published on:

  32. A large prospective study in patients with type 2 diabetes (T2D), the German D2C cohort, is presently being enumerated to investigate risk factors of incident cancer in diabetic patients.

    Authors: Hans-Werner Hense, Hiltraud Kajüter, Jürgen Wellmann and Wolf U Batzler
    Citation: Diabetology & Metabolic Syndrome 2011 3:15
    Content type: Research Published on:

  33. Insulin analogues are increasingly considered as an alternative to human insulin in the therapy of diabetes mellitus. Insulin analogues (IAs) are chemically different from human insulin and may have different ...

    Authors: Harald G Enzmann and Martina Weise
    Citation: Diabetology & Metabolic Syndrome 2011 3:14
    Content type: Review Published on:

  34. In order to provide comprehensive information on the differences in bioactivity between human insulin and insulin analogues, published in vitro comparisons of human insulin and the rapid acting analogues insulin ...

    Authors: Haim Werner and Ernst A Chantelau
    Citation: Diabetology & Metabolic Syndrome 2011 3:13
    Content type: Review Published on:

  35. There is a well established link between obesity and cancer. Emerging research is characterising this relationship further and delineating the specific role of excess visceral adiposity, as opposed to simple o...

    Authors: Claire L Donohoe, Suzanne L Doyle and John V Reynolds
    Citation: Diabetology & Metabolic Syndrome 2011 3:12
    Content type: Review Published on:

  37. Either endogenous or exogenous hyperinsulinemia in the setting of insulin resistance promotes phosphorylation and activation of farnesyltransferase, a ubiquitous enzyme that farnesylates Ras protein. Increased...

    Authors: Boris Draznin
    Citation: Diabetology & Metabolic Syndrome 2011 3:10
    Content type: Review Published on:

  38. The concordance of microalbuminuria and diabetic retinopathy (DR) has been well reported in persons with type 1 diabetes; however, for type 2 diabetes, there is paucity of data especially from population-based...

    Authors: Padmaja K Rani, Rajiv Raman, Aditi Gupta, Swakshyar S Pal, Vaitheeswaran Kulothungan and Tarun Sharma
    Citation: Diabetology & Metabolic Syndrome 2011 3:9
    Content type: Research Published on:

  39. Bus and truck drivers are apparently more involved in metabolic syndrome and its complications due to their working conditions. The related impacts are not only harmful for driver's health, but also may endang...

    Authors: Hamid R Saberi, Ali R Moravveji, Esmaeil Fakharian, Masoud Motalebi kashani and Ali R Dehdashti
    Citation: Diabetology & Metabolic Syndrome 2011 3:8
    Content type: Research Published on:

  40. Coronary artery disease (CAD) is among the main causes of death in developed countries, and diet and lifestyle can influence CAD incidence.

    Authors: Mauro Massao Takahashi, Erick Prado de Oliveira, Ana Lygia Rochitti de Carvalho, Lidiane Affonso de Souza Dantas, Franz Homero Paganini Burini, Kátia Cristina Portero-McLellan and Roberto Carlos Burini
    Citation: Diabetology & Metabolic Syndrome 2011 3:7
    Content type: Research Published on:

  44. Nonalcoholic fatty liver disease (NAFLD) is the most frequent disease associated with abnormal liver tests that is characterized by a wide spectrum of liver damage, ranging from simple macro vesicular steatosi...

    Authors: Fernanda BU Pulzi, Raul Cisternas, Murilo R Melo, Cristiane MF Ribeiro, Carlos A Malheiros and João E Salles
    Citation: Diabetology & Metabolic Syndrome 2011 3:3
    Content type: Research Published on:

  45. This paper reviews the incidence, pathogenetic mechanisms and management strategies of diabetes mellitus in patients with human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS). It cl...

    Authors: Sanjay Kalra, Bharti Kalra, Navneet Agrawal and AG Unnikrishnan
    Citation: Diabetology & Metabolic Syndrome 2011 3:2
    Content type: Review Published on:

  46. While several studies have identified the anaerobic threshold (AT) through the responses of blood lactate, ventilation and blood glucose others have suggested the response of the heart rate variability (HRV) a...

    Authors: Marcelo M Sales, Carmen Sílvia G Campbell, Pâmella K Morais, Carlos Ernesto, Lúcio F Soares-Caldeira, Paulo Russo, Daisy F Motta, Sérgio R Moreira, Fábio Y Nakamura and Herbert G Simões
    Citation: Diabetology & Metabolic Syndrome 2011 3:1
    Content type: Research Published on:

  48. Anxiety and depression contribute to poor disease outcomes among individuals with diabetes. This study aimed to assess the prevalence of anxiety and depression and to identify their associated factors includin...

    Authors: Ali Khan Khuwaja, Saima Lalani, Raheem Dhanani, Iqbal Syed Azam, Ghazala Rafique and Franklin White
    Citation: Diabetology & Metabolic Syndrome 2010 2:72
    Content type: Research Published on:

  49. To date, there have been no reports on the prevalence of adrenal masses in type 2 diabetic patients. The present study aimed to evaluate the prevalence of adrenal incidentaloma in type 2 diabetic patients in J...

    Authors: Naoki Hiroi, Mariko Sue, Aya Yoshihara, Takamasa Ichijo, Mayumi Yoshida-Hiroi, Mariko Higa and Gen Yoshino
    Citation: Diabetology & Metabolic Syndrome 2010 2:71
    Content type: Research Published on:

  50. Many trace elements, among which metals, are indispensable for proper functioning of a myriad of biochemical reactions, more particularly as enzyme cofactors. This is particularly true for the vast set of proc...

    Authors: Nicolas Wiernsperger and JeanRobert Rapin
    Citation: Diabetology & Metabolic Syndrome 2010 2:70
    Content type: Review Published on:

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