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  1. Content type: Research

    Type 2 diabetes is a chronic disease that is expanding at an alarming rate in the world. Research on individuals with type 2 diabetes showed that stressful life events cause problems in the effective managemen...

    Authors: Fereshteh Zamani-Alavijeh, Marzieh Araban, Hamid Reza Koohestani and Mahmood Karimy

    Citation: Diabetology & Metabolic Syndrome 2018 10:39

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  2. Content type: Research

    The aim of this study was to compare acute effects of turnip rapeseed oil rich with mono- and polyunsaturated fatty acids and cream on postprandial triglyceride levels and post-glucose load measures of insulin...

    Authors: Harri Juhani Saarinen, Sari Husgafvel, Hanna Pohjantähti-Maaroos, Marja Wallenius and Ari Palomäki

    Citation: Diabetology & Metabolic Syndrome 2018 10:38

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  3. Content type: Research

    The TCF7L2 rs7903146 variant is strongly associated with type 2 diabetes mellitus (T2DM). However, the mechanisms involved in this association remain unknown and may include extrapancreatic effects. The aim of th...

    Authors: Mari Cassol Ferreira, Maria Elizabeth Rossi da Silva, Rosa Tsuneshiro Fukui, Maria do Carmo Arruda-Marques and Rosa Ferreira dos Santos

    Citation: Diabetology & Metabolic Syndrome 2018 10:37

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  4. Content type: Research

    Individuals who suffer from mental illness are more prone to obesity and related co-morbidities, including the metabolic syndrome. Autopsies provide an outstanding platform for the macroscopic, microscopic and...

    Authors: Martin Roest Christensen, Anne Bugge, Mariam Elmegaard Malik, Jørgen Lange Thomsen, Niels Lynnerup, Jørgen Rungby and Jytte Banner

    Citation: Diabetology & Metabolic Syndrome 2018 10:36

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  5. Content type: Research

    A significant association is known between increased glycaemic variability and mortality in critical patients. To ascertain whether glycaemic profiles during the first week after liver transplantation might be...

    Authors: Elena Giráldez, Evaristo Varo, Ipek Guler, Carmen Cadarso-Suarez, Santiago Tomé, Patricia Barral, Antonio Garrote and Francisco Gude

    Citation: Diabetology & Metabolic Syndrome 2018 10:35

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  6. Content type: Research

    Metabolic syndrome (MetS) is one of the main reasons for elevated cardiovascular morbidity and mortality worldwide. Obese and overweight individuals are at high risk of developing these chronic diseases. The a...

    Authors: Basma Damiri, Mohammed S. Abualsoud, Amjad M. Samara and Sakhaa K. Salameh

    Citation: Diabetology & Metabolic Syndrome 2018 10:34

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  7. Content type: Research

    The adverse effects of cigarette smoking have been widely studied before, whilst the effects of hookah smoking has received less attention, although it is a common habit in the Middle East. Here we have invest...

    Authors: Sara Saffar Soflaei, Susan Darroudi, Maryam Tayefi, Abolfazl Nosrati Tirkani, Mohsen Moohebati, Mahmoud Ebrahimi, Habibollah Esmaily, Seyed Mohammad Reza Parizadeh, Ali Reza Heidari-Bakavoli, Gordon A. Ferns and Majid Ghayour-Mobarhan

    Citation: Diabetology & Metabolic Syndrome 2018 10:33

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  8. Content type: Review

    Chikungunya (CHIK) is a viral disease transmitted by mosquitoes. The first cases in Brazil were confirmed in 2014. Between 2016 and 2017, over 300,000 cases were identified during this period, with nearly 300 ...

    Authors: Francisca Kalline de Almeida Barreto, Renan Magalhães Montenegro Jr., Virginia Oliveira Fernandes, Rhaquel Oliveira, Lívia Aline de Araújo Batista, Akhtar Hussain and Luciano Pamplona de Góes Cavalcanti

    Citation: Diabetology & Metabolic Syndrome 2018 10:32

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  9. Content type: Research

    Purinergic receptors are expressed in different tissues including the retina. These receptors are involved in processes like cell growth, proliferation, activation and survival. ATP is the major activator of P...

    Authors: Jorge E. Mancini, Gustavo Ortiz, Constanza Potilinstki, Juan P. Salica, Emiliano S. Lopez, J. Oscar Croxatto and Juan E. Gallo

    Citation: Diabetology & Metabolic Syndrome 2018 10:31

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  10. Content type: Research

    Although the number of antihyperglycemic agents has expanded significantly, sulfonylureas (in particular gliclazide) remain an important option because of a variety of patient and health system factors. The la...

    Authors: Lawrence A. Leiter, Marina V. Shestakova and Ilhan Satman

    Citation: Diabetology & Metabolic Syndrome 2018 10:30

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  11. Content type: Research

    Most of prior studies to demonstrate the association between mean platelet volume (MPV) and type 2 diabetes mellitus (T2DM) risk were cross-sectional design with inconsistent results. In the present prospectiv...

    Authors: Zhaoyang Li, Jing Wang, Xu Han, Jing Yuan, Huan Guo, Xiaomin Zhang, Dan Zheng, Yuhan Tang, Handong Yang and Meian He

    Citation: Diabetology & Metabolic Syndrome 2018 10:29

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  12. Content type: Research

    Type 2 diabetes is a chronic disease associated with poorer health outcomes and decreased health related quality of life (HRQoL). The aim of this analysis was to explore the impact of a disease management prog...

    Authors: Sigrid Panisch, Tim Johansson, Maria Flamm, Henrike Winkler, Raimund Weitgasser and Andreas C. Sönnichsen

    Citation: Diabetology & Metabolic Syndrome 2018 10:28

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  13. Content type: Review

    Glycemic control has been considered a major therapeutic goal within the scope of diabetes management, as supported by robust observational and experimental evidence. However, the coexistence of micro and macr...

    Authors: Rodrigo Oliveira Moreira, Roberta Cobas and Raquel C. Lopes Assis Coelho

    Citation: Diabetology & Metabolic Syndrome 2018 10:26

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  14. Content type: Research

    Diabetics are at increased risk for impaired mobility and strength, frequently related to the disease control. Sarcopenia is the reduction of muscle mass associated with the decrease in muscle strength and/or ...

    Authors: Heloísa Trierweiler, Gabrielle Kisielewicz, Thaísa Hoffmann Jonasson, Ricardo Rasmussen Petterle, Carolina Aguiar Moreira and Victória Zeghbi Cochenski Borba

    Citation: Diabetology & Metabolic Syndrome 2018 10:25

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  15. Content type: Research

    With the increasing prevalence of metabolic syndrome (MS), there is a need to track and predict the development of MS. In this study, we established a Markov model to explore the natural history and predict th...

    Authors: Xiaoxian Jia, Qicai Chen, Peipei Wu, Meng Liu, Xiaoxiao Chen, Juan Xiao, Lili Chen, Pengpeng Zhang and Shumei Wang

    Citation: Diabetology & Metabolic Syndrome 2018 10:24

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  16. Content type: Research

    The aim of this study was to explore the predictors of QOL and health state and examine the relationship with glycemic control among type 2 diabetes mellitus (T2DM) patients.

    Authors: Syed Wasif Gillani, Irfan Altaf Ansari, Hisham A. Zaghloul, Mohi Iqbal Mohammad Abdul, Syed Azhar Syed Sulaiman and Mirza R. Baig

    Citation: Diabetology & Metabolic Syndrome 2018 10:23

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  17. Content type: Research

    Diabetes nephropathy is a microvascular complication associated with high morbidity and mortality in patients with type 1 diabetes, and its pathogenesis is not fully understood. Our aim was to evaluate the ass...

    Authors: Marcela Haas Pizarro, Deborah Conte Santos, Bianca Senger Vasconcelos Barros, Laura Gomes Nunes de Melo and Marilia Brito Gomes

    Citation: Diabetology & Metabolic Syndrome 2018 10:22

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  18. Content type: Research

    Obesity is known to be related to the development of type 2 diabetes mellitus (T2D). The most commonly used anthropometric indicator (body mass index [BMI]) presents several limitations such as the lack of pos...

    Authors: Fernando Gomez-Peralta, Cristina Abreu, Margarita Cruz-Bravo, Elvira Alcarria, Gala Gutierrez-Buey, Nir Y. Krakauer and Jesse C. Krakauer

    Citation: Diabetology & Metabolic Syndrome 2018 10:21

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  19. Content type: Research

    Obesity is associated with significant physical, psychosocial and economic burden globally. In Brazil, almost 50% of the population is either overweight or obese. The prevalence of morbid obesity increased by ...

    Authors: Ian Kudel, Jefferson S. Alves, Thiago de Menezes Goncalves, Kristjan Kull and Emil Nørtoft

    Citation: Diabetology & Metabolic Syndrome 2018 10:20

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  20. Content type: Letter to the Editor

    Patients with ischemic cardiomyopathy and severe left ventricular dysfunction have a worse survival prognosis than patients with preserved ventricular function. The role of diabetes in the long-term prognosis ...

    Authors: Thiago Hueb, Mauricio S. Rocha, Sergio F. Siqueira, Silvana Angelina D´Orio Nishioka, Giselle L. Peixoto, Marcos M. Saccab, Eduardo Gomes Lima, Rosa Maria Rahmi Garcia, José Antonio F. Ramires, Roberto Kalil Filho and Martino Martinelli Filho

    Citation: Diabetology & Metabolic Syndrome 2018 10:19

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  21. Content type: Research

    Vitamins are essential micronutrients with antioxidant potential that may provide a complementary treatment for patients with chronic diseases. Our aim was to assess the effect of vitamin supplementation on th...

    Authors: Maria E. Balbi, Fernanda S. Tonin, Antonio M. Mendes, Helena H. Borba, Astrid Wiens, Fernando Fernandez-Llimos and Roberto Pontarolo

    Citation: Diabetology & Metabolic Syndrome 2018 10:18

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  22. Content type: Research

    Diabetic retinopathy has a significant impact in every healthcare system. Despite that fact, there are few accurate estimates in the prevalence of DR in Brazil’s different geographic regions, particularly prol...

    Authors: Karla Rezende Guerra Drummond, Fernando Korn Malerbi, Paulo Henrique Morales, Tessa Cerqueira Lemos Mattos, André Araújo Pinheiro, Felipe Mallmann, Ricardo Vessoni Perez, Franz Schubert Lopes Leal, Laura Gomes Nunes de Melo and Marília Brito Gomes

    Citation: Diabetology & Metabolic Syndrome 2018 10:17

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  23. Content type: Short report

    This observational study aimed to assess the effectiveness of lixisenatide as add on therapy to basal insulin in diabetic type 2 patients previously treated with different insulin regimes.

    Authors: Tomislav Božek, Ines Bilić-Ćurčić, Maja Cigrovski Berković, Marina Gradišer, Tina Tićinović Kurir, Sanja Klobučar Majanović and Srećko Marušić

    Citation: Diabetology & Metabolic Syndrome 2018 10:16

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  24. Content type: Review

    Vascular endothelial dysfunction induced by hyperglycemia and elevated insulin resistance is a potent risk factor for cardiovascular disease and likely contributes to multiple chronic disease complications ass...

    Authors: Jung-Hoon Lee, Ruda Lee, Moon-Hyon Hwang, Marc T. Hamilton and Yoonjung Park

    Citation: Diabetology & Metabolic Syndrome 2018 10:15

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  25. Content type: Research

    To evaluate the utility of glycated haemoglobin A1c (HbA1c) alone and in combination with haematocrit (HCT) for screening gestational diabetes mellitus (GDM) between 12–16 gestational weeks.

    Authors: Kui Wu, Yan Cheng, Tingting Li, Ziwen Ma, Junxiu Liu, Qingying Zhang and Haidong Cheng

    Citation: Diabetology & Metabolic Syndrome 2018 10:14

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  26. Content type: Research

    Wistar Ottawa Karlsburg W (RT1u) rats (WOKW) are a model of the metabolic syndrome (MetS). Adipose tissue (AT) and peripheral nerves of WOKW rats exhibit up-regulated autophagy and inflammation corresponding w...

    Authors: J. Kosacka, M. Nowicki, S. Paeschke, P. Baum, M. Blüher and N. Klöting

    Citation: Diabetology & Metabolic Syndrome 2018 10:13

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  27. Content type: Research

    The aim of this study to compare the diagnostic accuracy of the metabolic syndrome (MetS) with the FINDRISC score to screen for type 2 diabetes mellitus T2DM in an overweight/obese population.

    Authors: Abraham S. Meijnikman, Christophe E. M. De Block, An Verrijken, Ilse Mertens and Luc F. Van Gaal

    Citation: Diabetology & Metabolic Syndrome 2018 10:12

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  28. Content type: Research

    The benefits of sodium glucose cotransporters 2 (SGLT2) inhibitors in patients with type 2 diabetes mellitus include plasma glucose control, reduction in body weight and blood pressure, and low risk of hypogly...

    Authors: Hiroki Nakajima, Sadanori Okada, Takako Mohri, Eiichiro Kanda, Naoyuki Inaba, Yoko Hirasawa, Hiroaki Seino, Hisamoto Kuroda, Toru Hiyoshi, Tetsuji Niiya and Hitoshi Ishii

    Citation: Diabetology & Metabolic Syndrome 2018 10:11

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  29. Content type: Research

    Use of combination antiretroviral therapy (cART) has led to significant reductions in morbidity and mortality. However, there is a growing concern about metabolic syndromes (MS), among patients receiving cART....

    Authors: Dula Dessalegn Bosho, Lemessa Dube, Teshale Ayele Mega, Dawit Abera Adare, Mikyas Gashaw Tesfaye and Tesfahun Chanie Eshetie

    Citation: Diabetology & Metabolic Syndrome 2018 10:10

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  30. Content type: Review

    There is ongoing scientific interest regarding comorbidities associated with the metabolic syndrome (MeTS). MeTS comprises a combination of parameters that predispose individuals to the development of type 2 d...

    Authors: Ellie C. Stefanadi, Georgios Dimitrakakis, Christos-Konstantinos Antoniou, Dimitrios Challoumas, Nikita Punjabi, Inetzi Aggeliki Dimitrakaki, Sangeeta Punjabi and Christodoulos I. Stefanadis

    Citation: Diabetology & Metabolic Syndrome 2018 10:9

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  31. Content type: Research

    Peripheral neuropathy is one of the most common microvascular complication of diabetes mellitus. This study is conducted to determine the prevalence of diabetic peripheral neuropathy (DPN) and its associated f...

    Authors: Nahla Khawaja, Jawad Abu-Shennar, Mohammed Saleh, Said S. Dahbour, Yousef S. Khader and Kamel M. Ajlouni

    Citation: Diabetology & Metabolic Syndrome 2018 10:8

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    The Correction to this article has been published in Diabetology & Metabolic Syndrome 2018 10:43

  32. Content type: Research

    People with type 2 diabetes (T2D) have impaired exercise capacity, even in the absence of complications, which is predictive of their increased cardiovascular mortality. Cardiovascular dysfunction is one poten...

    Authors: Rebecca L. Scalzo, Timothy A. Bauer, Kylie Harrall, Kerrie Moreau, Cemal Ozemek, Leah Herlache, Shawna McMillin, Amy G. Huebschmann, Jennifer Dorosz, Jane E. B. Reusch and Judith G. Regensteiner

    Citation: Diabetology & Metabolic Syndrome 2018 10:7

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  33. Content type: Research

    Familial partial lipodystrophy of the Dunnigan type is one of the most common inherited lipodystrophies variables. These individuals have important metabolic disorders that cause predisposition to various dise...

    Authors: Maria C. Foss-Freitas, Rafael C. Ferraz, Luciana Z. Monteiro, Patricia M. Gomes, Ricardo Iwakura, Luiz Carlos C. de Freitas and Milton C. Foss

    Citation: Diabetology & Metabolic Syndrome 2018 10:6

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  34. Content type: Research

    In HIV patients using HAART insulin resistance is a central pathophysiological condition that can contribute to the development of diabetes and cardiovascular complications. To examine the role of adipocyte ho...

    Authors: Marcelo Nardi Pedro, Daniela Oliveira Magro, Elizabete Urbano Pinaço Pinto da Silva, Dioze Guadagnini, Andrey Santos, Rogerio de Jesus Pedro and Mario José Abdalla Saad

    Citation: Diabetology & Metabolic Syndrome 2018 10:5

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  35. Content type: Research

    In humans and animal models, excessive intake of dietary fat, fructose and cholesterol has been linked to the development of non-alcoholic fatty liver disease (NAFLD). However, the individual roles of the diet...

    Authors: Victoria Svop Jensen, Henning Hvid, Jesper Damgaard, Helle Nygaard, Camilla Ingvorsen, Erik Max Wulff, Jens Lykkesfeldt and Christian Fledelius

    Citation: Diabetology & Metabolic Syndrome 2018 10:4

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  36. Content type: Research

    Although multidisciplinary treatment is recommended for type 2 diabetes mellitus and hypertension (HTN), there is a lack of scientific literature supporting the hypothesis of extending this treatment strategy ...

    Authors: Thiago Veiga Jardim, Sayuri Inuzuka, Luan Galvão, Leandra Anália Freitas Negretto, Rogério Orlow de Oliveira, Wanessa Faria Sá, Haroldo Silva de Souza, Andrea Crisitina Sousa, Patricia Silva Carneiro, Weimar Kunz Sebba Barroso, Ana Luiza Lima Sousa and Paulo César Veiga Jardim

    Citation: Diabetology & Metabolic Syndrome 2018 10:3

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  37. Content type: Research

    Gestational diabetes is a risk factor for future development of type 2 diabetes. The primary aim of this study was to estimate the prevalence of postpartum glucose tolerance status evaluation in pregnancies co...

    Authors: C. A. Cabizuca, P. S. Rocha, J. V. Marques, T. F. L. R. Costa, A. S. N. Santos, A. L. Schröder, C. A. G. Mello, H. D. Sousa, E. S. G. Silva, F. O. Braga, R. C. Abi-Abib and M. B. Gomes

    Citation: Diabetology & Metabolic Syndrome 2018 10:2

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  38. Content type: Research

    No proper data on prognosis and management of type-2 diabetic ST elevation myocardial infarction (STEMI) patients with culprit obstructive lesion and multivessel non obstructive coronary stenosis (Mv-NOCS) exi...

    Authors: Raffaele Marfella, Celestino Sardu, Maria Luisa Balestrieri, Mario Siniscalchi, Fabio Minicucci, Giuseppe Signoriello, Paolo Calabrò, Ciro Mauro, Gorizio Pieretti, Antonino Coppola, Gianfranco Nicoletti, Maria Rosaria Rizzo, Giuseppe Paolisso and Michelangela Barbieri

    Citation: Diabetology & Metabolic Syndrome 2018 10:1

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  39. Content type: Research

    Exercise stimulates the production of fibronectin type III domain-containing protein 5 (FNDC5), which is cleaved to release a protein called irisin. This protein induces browning of white adipose tissue result...

    Authors: Carolina Archundia-Herrera, Maciste Macias-Cervantes, Bernardo Ruiz-Muñoz, Katya Vargas-Ortiz, Carlos Kornhauser and Victoriano Perez-Vazquez

    Citation: Diabetology & Metabolic Syndrome 2017 9:101

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  40. Content type: Research

    Diabetics have increased risks for cardiovascular disease (CVD) and mortality, reducing their life expectancy by up to 15 years. Type 2 diabetes mellitus specifically increases the risk for cardiovascular mort...

    Authors: Andréa Cristina Sousa, Thiago Veiga Jardim, Thiago Olivera Costa, Fabrício Galdino Magalhães, Marcos Paulo Marinho Montelo, Weimar K. Barroso Souza, Paulo César Brandão Veiga Jardim and Ana Luiza Lima Sousa

    Citation: Diabetology & Metabolic Syndrome 2017 9:98

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  41. Content type: Research

    Type 1 diabetes patients have a higher risk of developing hypoglycemia or hyperglycemia during physical activity, which may compromise their safety during exercise but results regarding the exercise capacity o...

    Authors: Milena S. Nascimento, Carolina F. Espindola, Cristiane do Prado, Melina Blanco Amarins, Ana Lucia Potenza, Luciana Pacheco, Erica Santos and Teresa Cristina A. Vieira

    Citation: Diabetology & Metabolic Syndrome 2017 9:100

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  42. Content type: Short report

    Obesity-mediated oxidative stress results in mitochondrial dysfunction, which has been implicated in the pathogenesis of metabolic syndrome and T2DM. Recently, mitophagy, a cell-reparative process has emerged ...

    Authors: Shipra Bhansali, Anil Bhansali and Veena Dhawan

    Citation: Diabetology & Metabolic Syndrome 2017 9:99

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  43. Content type: Research

    Type II diabetes is an important health problem with a complex connection to obesity, leading to a broad range of cardiovascular complications. Insulin therapy often results in weight gain and does not always ...

    Authors: Tomislav Bozek, Antonela Blazekovic, Matea Nikolac Perkovic, Kristina Gotovac Jercic, Aleksandra Sustar, Lea Smircic-Duvnjak, Tiago F. Outeiro, Nela Pivac and Fran Borovecki

    Citation: Diabetology & Metabolic Syndrome 2017 9:97

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  44. Content type: Research

    Diabetes is a progressive disease needing multiple drugs for achieving and maintaining good glycemic control. Sodium-glucose co-transporter 2 inhibitors (SGLT2i) is a novel class of anti-diabetic agent which o...

    Authors: Yotsapon Thewjitcharoen, Nalin Yenseung, Areeya Malidaeng, Soontaree Nakasatien, Phawinpon Chotwanvirat, Sirinate Krittiyawong, Ekgaluck Wanothayaroj and Thep Himathongkam

    Citation: Diabetology & Metabolic Syndrome 2017 9:96

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  45. Content type: Research

    The interplay between adiponectin and resistin, the two adipokines of opposite effects, may determine the metabolic profile of obese individuals and development of obesity-related complications. The current st...

    Authors: Marta Izabela Jonas, Alina Kurylowicz, Zbigniew Bartoszewicz, Wojciech Lisik, Maurycy Jonas, Justyna Domienik-Karlowicz and Monika Puzianowska-Kuznicka

    Citation: Diabetology & Metabolic Syndrome 2017 9:95

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  46. Content type: Short report

    To explore the impact of glycaemic control (HbA1c) on functional capacity during cardio-pulmonary exercise testing in people with type 1 diabetes.

    Authors: Othmar Moser, Max L. Eckstein, Olivia McCarthy, Rachel Deere, Stephen C. Bain, Hanne L. Haahr, Eric Zijlstra and Richard M. Bracken

    Citation: Diabetology & Metabolic Syndrome 2017 9:93

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  47. Content type: Research

    Diabetic patients may be more susceptible to myocardial injury after coronary interventions. Thus, the aim of this study was to assess the release of cardiac biomarkers, CK-MB and troponin, and the findings of...

    Authors: Paulo Cury Rezende, Whady Hueb, Rosa Maria Rahmi, Thiago Luis Scudeler, Diogo Freitas Cardoso de Azevedo, Cibele Larrosa Garzillo, Carlos Alexandre Wainrober Segre, Jose Antonio Franchini Ramires and Roberto Kalil Filho

    Citation: Diabetology & Metabolic Syndrome 2017 9:92

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