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  1. The associations between serum free triiodothyronine (FT3) and diabetic peripheral neuropatprohy (DPN)/carotid atherosclerotic lesions in euthyroid patients with type 2 diabetes are still unclear. The purpose ...

    Authors: Mei-Fang Li, Jiang-Feng Ke, Shuai Li, Jun-Wei Wang, Zhi-Hui Zhu and Jing-Bo Li
    Citation: Diabetology & Metabolic Syndrome 2021 13:142
    Content type: Research Published on:

  2. Similar to other non-communicable diseases (NCDs), people who develop cardiovascular disease (CVD) typically have more than one risk factor. The clustering of cardiovascular risk factors begins in youth, early...

    Authors: Fatima Mezhal, Abderrahim Oulhaj, Abdishakur Abdulle, Abdulla AlJunaibi, Abdulla Alnaeemi, Amar Ahmad, Andrea Leinberger-Jabari, Ayesha S. Al Dhaheri, E. Murat Tuzcu, Eiman AlZaabi, Fatma Al-Maskari, Fatme Alanouti, Fayza Alameri, Habiba Alsafar, Hamad Alblooshi, Juma Alkaabi…
    Citation: Diabetology & Metabolic Syndrome 2021 13:140
    Content type: Research Published on:

  3. Coronary artery disease is a leading cause of morbidity and mortality among patients with diabetes. Previously, we demonstrated that branched-chain amino acids (BCAAs) showed cardioprotective effects against c...

    Authors: Atsushi Morio, Rie Tsutsumi, Shiho Satomi, Takashi Kondo, Hirotsugu Miyoshi, Takahiro Kato, Masashi Kuroda, Tadahiro Kitamura, Kenta Hara, Noboru Saeki, Hiroshi Sakaue and Yasuo M. Tsutsumi
    Citation: Diabetology & Metabolic Syndrome 2021 13:139
    Content type: Research Published on:

  4. FTO gene is considered to play an important role in many metabolic diseases. Evidence from studies indicated the possible association between the FTO rs9939609 polymorphisms with serum lipid profile. Therefore...

    Authors: Vahideh Jalili, Zohreh Mokhtari, Samira Rastgoo, Azadeh Hajipour, Fatemeh Bourbour, Maryam Gholamalizadeh, Alireza Mosavi Jarrahi, Sepehr JavadiKooshesh, Alireza Moslem, Morteza Abdollahi and Saeid Doaei
    Citation: Diabetology & Metabolic Syndrome 2021 13:138
    Content type: Research Published on:

  5. Diabetic nephropathy (DN) is a common complication of diabetes mellitus. Accumulating studies suggest that the deregulation of circular RNA (circRNA) is involved in DN pathogenesis. This study aimed to investi...

    Authors: Rina Wu, Zheli Niu, Guangwei Ren, Lin Ruan and Lijun Sun
    Citation: Diabetology & Metabolic Syndrome 2021 13:137
    Content type: Research Published on:

  6. Coronary artery calcium score and glycated hemoglobin(HbA1c) are both considered risk factors for coronary heart disease. However, the relationship between coronary artery calcium score and HbA1c is still uncl...

    Authors: Jing Yu and Bo Gao
    Citation: Diabetology & Metabolic Syndrome 2021 13:136
    Content type: Research Published on:

  7. Since the development of antiretroviral therapy (ART) with TDF plus 3TC plus EFV, this specific regimen has not been studied enough with long-term lipid and uric acid monitoring.

    Authors: Dafeng Liu, Xinyi Zhang, Jun Kang, Fengjiao Gao, Yinsheng He and Shenghua He
    Citation: Diabetology & Metabolic Syndrome 2021 13:135
    Content type: Research Published on:

  8. As studies on ethnic disparities in metabolic syndrome and its risk factors in Taiwan are still rare, the aims of this study were: (1) to detect the differences in the rates of metabolic syndrome, obesity and ...

    Authors: Chih-Ying Lin, Hui-Jung Hung, Chi-Jung Chung, Chia-Ti Huang, Trong-Neng Wu and Chiu-Ying Chen
    Citation: Diabetology & Metabolic Syndrome 2021 13:134
    Content type: Research Published on:

  9. Growing body of evidence suggest the association between SNP − 11377 C > G and SNP + 276 G > T polymorphisms of adiponectin gene with type 2 diabetes (T2D). However, these findings have not been conclusive and...

    Authors: Mahrokh Alimi, Mohammad Taghi Goodarzi and Mehdi Nekoei
    Citation: Diabetology & Metabolic Syndrome 2021 13:133
    Content type: Research Published on:

  10. Type 2 diabetes mellitus (T2DM) is a major public health concern with growing prevalence with multiple debilitating complications. GlycaCare-II is a proprietary herbal formulation supplement for T2DM containin...

    Authors: Muhammed Majeed, Anju Majeed, Kalyanam Nagabhusahnam, Lakshmi Mundkur and Shaji Paulose
    Citation: Diabetology & Metabolic Syndrome 2021 13:132
    Content type: Research Published on:

  12. Metabolic syndrome is a major public health challenge in both developed and developing countries. The burden of this disease is high, even in patients with psychiatric disorders. However, very little is known ...

    Authors: Dilnessa Fentie, Tariku Derese, Bekele Yazie and Yibeltal Getachew
    Citation: Diabetology & Metabolic Syndrome 2021 13:130
    Content type: Research Published on:

  13. Altered body composition is known to be related to abnormal metabolism. The aim of this study was to determine the association between the fat-to-muscle ratio (FMR) and metabolic disorders in type 2 diabetes (...

    Authors: Dixing Liu, Jiana Zhong, Yuting Ruan, Zhen Zhang, Jia Sun and Hong Chen
    Citation: Diabetology & Metabolic Syndrome 2021 13:129
    Content type: Research Published on:

  14. Albumin, along with other proteins, is abnormally eliminated via the urine during early stages of diabetic nephropathy. Moreover, endothelial dysfunction (ED) accompanying early diabetic nephropathy may develo...

    Authors: José Juan Sánchez-Hidalgo, Juan Antonio Suárez-Cuenca, José Juan Lozano-Nuevo, Víctor Hugo García-López, María Graciela Leal-Gutiérrez, Sein Antonio León-Angel, María Leslye Ramírez-Villa, Martha Elena Rodea-Rubio, José Enrique González-Hernández, José Antonio Canela-Mayoral, Eduardo Murillo-Heredia, Eduardo Vera-Gómez, Alejandro Hernández-Patricio, Carlos Ramiro Zamora-Alemán, Gabriela Alexandra Domínguez-Pérez, Juan Ariel Gutiérrez-Buendia…
    Citation: Diabetology & Metabolic Syndrome 2021 13:128
    Content type: Research Published on:

  15. Both pulmonary tuberculosis (PTB) and diabetes mellitus (DM) are major global public health problems. We estimated the global, regional, and national prevalence of diabetes mellitus in a population with PTB.

    Authors: Minmin Li, Tao Chen, Zhongqiu Hua, Hong Yan, Duolao Wang, Zhaoqing Li, Yijun Kang, Ni Zhu and Chao Li
    Citation: Diabetology & Metabolic Syndrome 2021 13:127
    Content type: Research Published on:

  16. Post-transplant diabetes mellitus (PTDM) occurs in 10–30% of kidney transplant recipients. However, its impact on mortality and graft survival is still ambiguous. Therefore, the current study aimed to analyze ...

    Authors: Hailing Lin, Jiqiang Yan, Lei Yuan, Beibei Qi, Zhujing Zhang, Wanlu Zhang, Aihua Ma and Fuwan Ding
    Citation: Diabetology & Metabolic Syndrome 2021 13:126
    Content type: Review Published on:

  17. Gestational diabetes mellitus (GDM) is the most frequent medical complication of pregnancy. This condition is manifested by glucose intolerance resulting in hyperglycemia of variable severity during pregnancy....

    Authors: Yaer Chen, Chunbo Qiu, Jie Chen, Lu Li, Jichao Xu and Zhiren Sheng
    Citation: Diabetology & Metabolic Syndrome 2021 13:125
    Content type: Research Published on:

  18. Regular physical exercise can improve insulin resistance in insulin target tissues. However, the mechanisms about the beneficial effect of exercise on insulin resistance are not yet fully resolved. This study ...

    Authors: Zhengxi Huang, Jialing Tang and Kai Ji
    Citation: Diabetology & Metabolic Syndrome 2021 13:124
    Content type: Research Published on:

  19. People with diabetes are at a greater risk of serious complications from Coronavirus disease (COVID-19). Self-management of diabetes is therefore of paramount importance. The purpose of this study is to compar...

    Authors: Shahina Pardhan, Md. Saiful Islam, Guillermo F. López-Sánchez, Tirthalal Upadhyaya and Raju P. Sapkota
    Citation: Diabetology & Metabolic Syndrome 2021 13:123
    Content type: Research Published on:

  21. Non-alcoholic fatty liver disease (NAFLD) patients are at a substantial risk for developing cardiovascular disease (CVD). High-density lipoprotein (HDL) is well known to have protective effects against the dev...

    Authors: Sara Karami, Hossein Poustchi, Negar Sarmadi, Amir Reza Radmard, Fatemeh Ali Yari, Abbas Pakdel and Parisa Shabani
    Citation: Diabetology & Metabolic Syndrome 2021 13:121
    Content type: Research Published on:

  22. One possible reason for increased mortality due to SARS-CoV-2 in patients with diabetes is from the complication of diabetic ketoacidosis (DKA).

    Authors: Saad Alhumaid, Abbas Al Mutair, Zainab Al Alawi, Ali A. Rabaan, Mohammed A. Alomari, Sadiq A. Al Salman, Ahmed S. Al-Alawi, Mohammed H. Al Hassan, Hesham Alhamad, Mustafa A. Al-kamees, Fawzi M. Almousa, Hani N. Mufti, Ali M. Alwesabai, Kuldeep Dhama, Jaffar A. Al-Tawfiq and Awad Al-Omari
    Citation: Diabetology & Metabolic Syndrome 2021 13:120
    Content type: Research Published on:

  23. Time in range (TIR) is advocated as key metric of glycemic control and is reported to be associated with microvascular complications of diabetes. Sudomotor dysfunction is among the earliest detectable diabetic...

    Authors: Zhou-qin Feng, Qing-yu Guo, Wei Wang, Yan-yu Yuan, Xu-guang Jin, Hui Zhou, Jun Liu, Hai-yan Lei, Xin-yi Yang, Jun Liu, Bin Lu, Jia-qing Shao and Ping Gu
    Citation: Diabetology & Metabolic Syndrome 2021 13:119
    Content type: Research Published on:

  24. Type 1 diabetes (T1D) is a major risk factor for cardiovascular disease (CVD). Matrix metalloproteinase-14 (MMP-14) is involved in the development of atherosclerosis and CVD. The main aim was to explore the as...

    Authors: Eva Olga Melin, Jonatan Dereke and Magnus Hillman
    Citation: Diabetology & Metabolic Syndrome 2021 13:118
    Content type: Research Published on:

  26. The bone formation ability of type 2 diabetes is inhibited, and exercise can effectively improve the bone formation of T2DM. However, whether exercise can mediate the Wnt3a/β-catenin pathway to improve the mec...

    Authors: Xianghe Chen, Kang Yang, Peng Sun, Renqing Zhao, Bo Liu and Pengcheng Lu
    Citation: Diabetology & Metabolic Syndrome 2021 13:116
    Content type: Research Published on:

  27. Hypertension and diabetes are among the most important risk factors of cardiovascular diseases. Klotho and SIRT1 are known as anti-aging factors with beneficial effects on cardiovascular system. In this study ...

    Authors: Mahboobeh Yeganeh-Hajahmadi, Hamid Najafipour, Farzaneh Rostamzadeh and Ahmad Naghibzadeh-Tahami
    Citation: Diabetology & Metabolic Syndrome 2021 13:115
    Content type: Research Published on:

  28. A variety of health problems, such as metabolic syndrome (MetS), have been linked to sleep disorders. While numerous epidemiological studies have shown a U-shaped relationship between sleep duration and poor h...

    Authors: Shideh Rafati, Maryam Isheh, Abnoos Azarbad, Farhad Ghadiri Soufi, Arash Rahimi and Masoumeh Kheirandish
    Citation: Diabetology & Metabolic Syndrome 2021 13:114
    Content type: Research Published on:

  29. It has been described that physiological changes in glucose metabolism, represented by insulin resistance (IR), are predicted during pubertal evolution, and obesity may be associated with its persistence even ...

    Authors: Ivanice Fernandes Barcellos Gemelli, Thais Rasia Silva, Edson dos Santos Farias, Maria Teresa Anselmo Olinto and Poli Mara Spritzer
    Citation: Diabetology & Metabolic Syndrome 2021 13:113
    Content type: Research Published on:

  30. Nonalcoholic fatty liver disease (NAFLD) is one of the most common causes of liver transaminases elevation and a global health concern.

    Authors: Maryam jarhahzadeh, Pezhman Alavinejad, Farnaz Farsi, Durdana Husain and Afshin Rezazadeh
    Citation: Diabetology & Metabolic Syndrome 2021 13:112
    Content type: Research Published on:

  31. Periodontal disease is one of the most frequent comorbidities in diabetic patients and can contribute to poor blood glucose control.

    Authors: Diana Vilela Azzi, Andressa Naira de Jesus Pereira, Viviam de Oliveira Silva, Renata de Carvalho Foureaux, Andressa Ribeiro Veiga Lima, Robson Sfaciotti Barducci, Adriana Silva Albuquerque, Gabriel Lasmar Reis, Raphael Ricon de Oliveira, Eric Francelino Andrade, Márcio Gilberto Zangeronimo, Antonio Chalfun-Júnior and Luciano José Pereira
    Citation: Diabetology & Metabolic Syndrome 2021 13:111
    Content type: Research Published on:

  32. Obesity is a complex disease with an increasing prevalence worldwide. There are different weight-management options for obesity treatment, including dietary control, exercise, surgery, and medication. Medicati...

    Authors: Nader Salari, Samira Jafari, Niloofar Darvishi, Elahe Valipour, Masoud Mohammadi, Kamran Mansouri and Shamarina Shohaimi
    Citation: Diabetology & Metabolic Syndrome 2021 13:110
    Content type: Research Published on:

    The Correction to this article has been published in Diabetology & Metabolic Syndrome 2022 14:68

  33. The present study performed two distinct meta-analyses with common outcomes (sperm parameters); one was performed in obese individuals (and non-obese controls) and the other in diabetic individuals (and non-di...

    Authors: Ou Zhong, Lin Ji, Jinyuan Wang, Xiaocan Lei and Hua Huang
    Citation: Diabetology & Metabolic Syndrome 2021 13:109
    Content type: Research Published on:

  34. Long non-coding RNAs (lncRNAs) have been reported to play vital roles in diabetic nephropathy (DN). The aim of this study was to explore the function of mechanism of lncRNA KCNQ1 opposite strand/antisense tran...

    Authors: Li Zhao, Huaqian Chen, Lin Wu, Zhengdong Li, Ren Zhang, Yan Zeng, Tao Yang and Hualing Ruan
    Citation: Diabetology & Metabolic Syndrome 2021 13:108
    Content type: Research Published on:

  35. Diabetic nephropathy (DN) is the most common causes of end-stage renal disease. Long non-coding RNA cyclin-dependent kinase inhibitor 2B antisense RNA 1 (CDKN2B-AS1) is connected with the development of DN, bu...

    Authors: Min Xiao, Shoujun Bai, Jing Chen, Yaxi Li, Shu Zhang and Zhao Hu
    Citation: Diabetology & Metabolic Syndrome 2021 13:107
    Content type: Research Published on:

  36. Evidence suggests gut microbiome is associated with diabetes. However, it’s unclear whether the association remains in non-diabetic participants. A Chinese monozygotic twin study, in which the participants are...

    Authors: Ke Yu, Cai-Guo Yu, Xing-Qi Yin, Zong-Wei Wang, Xiao-Bo Wang, Li-Li Wang, Shuang Guo, Ya-Xin An and Dong Zhao
    Citation: Diabetology & Metabolic Syndrome 2021 13:106
    Content type: Research Published on:

  37. Hyperglycemia is associated with albuminuria and renal glomerular endothelial dysfunction in patients with diabetic nephropathy. The mTOR and RhoA/ROCK signaling pathways are involved in glomerular filtration ...

    Authors: Xiaolin Chen, Jianhui Chen, Xianfan Li and Zengpu Yu
    Citation: Diabetology & Metabolic Syndrome 2021 13:105
    Content type: Research Published on:

  38. Studies highlight the inaccuracy of glycated hemoglobin (HbA1c) for the assessment of glycemic control in dialysis diabetics and suggest the use of continuous glucose monitoring (CGM) as an alternative. Of the...

    Authors: Marcelo Rocha Nasser Hissa, Priscilla Nogueira Gomes Hissa, Sérgio Botelho Guimarães and Miguel Nasser Hissa
    Citation: Diabetology & Metabolic Syndrome 2021 13:104
    Content type: Research Published on:

  39. Abnormal glucose metabolism including diabetes (DM) and prediabetes (pre-DM) have been reported as predictors of poorer outcomes after acute myocardial infarction (AMI). However, the prognostic value of pre-DM...

    Authors: Side Gao, Wenjian Ma, Sizhuang Huang, Xuze Lin and Mengyue Yu
    Citation: Diabetology & Metabolic Syndrome 2021 13:103
    Content type: Research Published on:

  40. Deterioration of sleep quality has been reported to contribute to the incidence of diabetes and may be responsible for glycemic status in diabetes. The present study explored the relationship between sleep qua...

    Authors: Yang Yang, Li-hua Zhao, Dan-dan Li, Feng Xu, Xiao-hua Wang, Chun-feng Lu, Chun-hua Wang, Chao Yu, Xiu-lin Zhang, Li-yan Ning, Xue-qin Wang, Jian-bin Su and Li-hua Wang
    Citation: Diabetology & Metabolic Syndrome 2021 13:102
    Content type: Research Published on:

  42. Previous studies that explored the relationship of serum albumin with diabetic peripheral neuropathy (DPN) have indicated inconsistent results. Thus, the present study aimed to evaluated the association betwee...

    Authors: Pijun Yan, Qian Tang, Yuru Wu, Qin Wan, Zhihong Zhang, Yong Xu, Jianhua Zhu and Ying Miao
    Citation: Diabetology & Metabolic Syndrome 2021 13:100
    Content type: Research Published on:

  43. There is currently a large arsenal of antidiabetic drugs available to treat type 2 diabetes (T2D). However, this is a serious chronic disease that affects millions of adults worldwide and is responsible for se...

    Authors: Freddy G. Eliaschewitz and Luis Henrique Canani
    Citation: Diabetology & Metabolic Syndrome 2021 13:99
    Content type: Review Published on:

  44. Obesity-associated coronary heart disease (CHD) risk is higher in women than in men with type 2 diabetes (T2DM). Resistin, an adipokine secreted by adispose tissue, may contribute to this higher risk.

    Authors: A. Giandalia, A. Alibrandi, L. Giorgianni, F. Lo Piano, F. Consolo, G. Longo Elia, B. Asztalos, D. Cucinotta, G. Squadrito and G. T. Russo
    Citation: Diabetology & Metabolic Syndrome 2021 13:98
    Content type: Research Published on:

  45. Type 2 diabetes mellitus (T2DM) affects the social economy and quality of life, and has become a major threat to human health. This observation aimed to study the possibility of serum HOTAIR as a diagnostic in...

    Authors: Huiyun Wang, Yu Xia and Yanxia Zhang
    Citation: Diabetology & Metabolic Syndrome 2021 13:97
    Content type: Research Published on:

  46. A retrospective observational study was conducted to assess the prevalence of maturity onset diabetes of the young (MODY) in a large paediatric population of Southern Italy newly diagnosed with diabetes. Clini...

    Authors: Stefano Passanisi, Giuseppina Salzano, Bruno Bombaci and Fortunato Lombardo
    Citation: Diabetology & Metabolic Syndrome 2021 13:96
    Content type: Research Published on:

  47. In 2019, a new virus known as severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) has emerged. Coronavirus disease 2019 (COVID-19) was classified as a pandemic in a short period of time. In order...

    Authors: Claudia Eberle and Stefanie Stichling
    Citation: Diabetology & Metabolic Syndrome 2021 13:95
    Content type: Review Published on:

  48. Glucose monitoring is vital for glycemic control in patients with diabetes mellitus (DM). Continuous glucose monitoring (CGM) measures whole-day glucose levels. Hemoglobin A1c (HbA1c) is a vital outcome predic...

    Authors: Jen-Hung Huang, Yung-Kuo Lin, Ting-Wei Lee, Han-Wen Liu, Yu-Mei Chien, Yu-Chun Hsueh, Ting-I Lee and Yi-Jen Chen
    Citation: Diabetology & Metabolic Syndrome 2021 13:94
    Content type: Research Published on:

  49. Sarcopenia was a frequent chronic complication in patients with type 2 diabetes mellitus (T2DM), and previous evidence showed conflicting results regarding the prevalence and risk factors of sarcopenia in T2DM...

    Authors: Yaqin Ai, Ruoxin Xu and Lingping Liu
    Citation: Diabetology & Metabolic Syndrome 2021 13:93
    Content type: Research Published on:

  50. A young female patient, diagnosed with diabetes mellitus at the age of 28 years old in 2009, carries KCNJ11 R136C by whole exome sequencing and her daughter doesn’t carry this mutation. Bioinformatics software pr...

    Authors: Yaning Chen, Xiaodong Hu, Jia Cui, Mingwei Zhao and Hebin Yao
    Citation: Diabetology & Metabolic Syndrome 2021 13:91
    Content type: Short report Published on:


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