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  1. The TOMM20 gene was previously identified as differentially expressed and methylated between severely obese subjects with and without metabolic syndrome (MS). Since metabolic complications do not affect all obese...

    Authors: Juan de Toro-Martín, Frédéric Guénard, André Tchernof, Yves Deshaies, Louis Pérusse, Frédéric-Simon Hould, Stéfane Lebel, Picard Marceau and Marie-Claude Vohl
    Citation: Diabetology & Metabolic Syndrome 2016 8:55
    Content type: Research Published on:

  2. We aimed to examine the relationship between the occurrence of hypo-/hyperglycemia and HbA1c values, as assessed by continuous glucose monitoring (CGM) in patients with type 1 diabetes.

    Authors: Daisuke Tsujino, Rimei Nishimura, Yoshiko Onda, Chiaki Seo, Kiyotaka Ando, Aya Morimoto and Kazunori Utsunomiya
    Citation: Diabetology & Metabolic Syndrome 2016 8:53
    Content type: Research Published on:

  3. In practice, there is increasing recognition of the importance of hypothalamic pituitary adrenal axis in the cardiovascular disease progression. The association of brain natriuretic peptide with obesity and ch...

    Authors: Mona Schaalan, Waleed Mohamed and Rania Rahmo
    Citation: Diabetology & Metabolic Syndrome 2016 8:52
    Content type: Research Published on:

  4. This review aims at summarizing the present knowledge on the clinical consequences of concomitant coeliac disease (CD) in adult patients with type 1 diabetes mellitus (T1DM). The cause of the increased prevale...

    Authors: Sjoerd F. Bakker, Maarten E. Tushuizen, Boudewina M. E. von Blomberg, Hetty J. Bontkes, Chris J. Mulder and Suat Simsek
    Citation: Diabetology & Metabolic Syndrome 2016 8:51
    Content type: Review Published on:

  5. Type 2 diabetes mellitus (DM) globally affects 18–20 % of adults over the age of 65 years. Diabetic kidney disease (DKD) is one of the most frequent and dangerous complications of DM2, affecting about one-thir...

    Authors: Roberto Pecoits-Filho, Hugo Abensur, Carolina C. R. Betônico, Alisson Diego Machado, Erika B. Parente, Márcia Queiroz, João Eduardo Nunes Salles, Silvia Titan and Sergio Vencio
    Citation: Diabetology & Metabolic Syndrome 2016 8:50
    Content type: Review Published on:

  6. The aim of this study was to determine the impact of metabolic syndrome (MetS) on lipid target achievements in the Arabian Gulf.

    Authors: Ibrahim Al-Zakwani, Wael Al Mahmeed, Abdullah Shehab, Mohamed Arafah, Ali T. Al-Hinai, Omer Al Tamimi, Mahmoud Al Awadhi, Shorook Al Herz, Faisal Al Anazi, Khalid Al Nemer, Othman Metwally, Akram Alkhadra, Mohammed Fakhry, Hossam Elghetany, Abdel Razak Medani, Afzal Hussein Yusufali…
    Citation: Diabetology & Metabolic Syndrome 2016 8:49
    Content type: Research Published on:

  7. Women with gestational diabetes mellitus (GDM) are required to control their blood glucose shortly after GDM diagnosis to minimize adverse pregnancy outcomes. A real time-continuous glucose monitoring system (...

    Authors: Eman Alfadhli, Eman Osman and Taghreed Basri
    Citation: Diabetology & Metabolic Syndrome 2016 8:48
    Content type: Research Published on:

  8. Sex hormone binding globulin (SHBG), a glycoprotein produced by hepatocytes that transports testosterone and other steroids in plasma, is a marker for developing metabolic syndrome and T2DM. SHBG is present in...

    Authors: Swapna Dharashivkar, Lawrence Wasser, Richard N. Baumgartner, Jeffrey C. King and Stephen J. Winters
    Citation: Diabetology & Metabolic Syndrome 2016 8:47
    Content type: Research Published on:

  9. This study aims to assess serum vaspin in early stages of glucose intolerance and in the presence of metabolic syndrome (MetS); and to evaluate vaspin correlation to different cardio-metabolic parameters and a...

    Authors: Rumyana Dimova, Tsvetalina Tankova, Georgi Kirilov, Nevena Chakarova, Lilia Dakovska and Greta Grozeva
    Citation: Diabetology & Metabolic Syndrome 2016 8:46
    Content type: Research Published on:

  10. Sodium-glucose co-transporter-2 (SGLT2) inhibitors are new oral antidiabetic drugs that reduce hyperglycemia by promoting urinary glucose excretion. Glycosuria produced by SGLT2 inhibitors is associated with w...

    Authors: Teruo Jojima, Takanori Tomotsune, Toshie Iijima, Kazumi Akimoto, Kunihiro Suzuki and Yoshimasa Aso
    Citation: Diabetology & Metabolic Syndrome 2016 8:45
    Content type: Research Published on:

  12. Gestational diabetes mellitus (GDM) increases the risk for preeclampsia and macrosomia. GDM is conventionally diagnosed by an oral glucose tolerance test (OGTT). Hemoglobin A1c (HbA1c) is a marker for the aver...

    Authors: Ingrid Hov Odsæter, Arne Åsberg, Eszter Vanky, Siv Mørkved, Signe Nilssen Stafne, Kjell Åsmund Salvesen and Sven Magnus Carlsen
    Citation: Diabetology & Metabolic Syndrome 2016 8:43
    Content type: Research Published on:

  13. The aim of this study was to investigate the association and interaction of metabolic syndrome (MetS) and estrogen receptor alpha 1 (ESR1) gene polymorphisms on cardiovascular autonomic neuropathy (CAN).

    Authors: Fangfang Zeng, Linuo Zhou and Zihui Tang
    Citation: Diabetology & Metabolic Syndrome 2016 8:42
    Content type: Research Published on:

  14. Poor glycemic control in patients with type 2 diabetes is commonly recorded worldwide; Latin America (LA) is not an exception. Barriers to intensifying insulin therapy and which barriers are most likely to neg...

    Authors: Bruno Linetzky, Brad Curtis, Gustavo Frechtel, Renan Montenegro Jr., Miguel Escalante Pulido, Oded Stempa, Janaina Martins de Lana and Juan José Gagliardino
    Citation: Diabetology & Metabolic Syndrome 2016 8:41
    Content type: Research Published on:

  15. The association of anthropometric (waist circumference) and hemodynamic (blood pressure) changes with abnormalities in glucose and lipid metabolism has been motivation for a lot of discussions in the last 30 y...

    Authors: Heno F. Lopes, Maria Lúcia Corrêa-Giannella, Fernanda M. Consolim-Colombo and Brent M. Egan
    Citation: Diabetology & Metabolic Syndrome 2016 8:40
    Content type: Review Published on:

  16. Describe the overweight frequency (overweight and obesity) and identify the factors associated with this in children and adolescents with type 1 diabetes mellitus (T1DM) treated at a University Children’s Hosp...

    Authors: Verônica Medeiros da Costa, Patricia de Carvalho Padilha, Géssica Castor Fontes de Lima, Aline Alves Ferreira, Jorge Luiz Luescher, Luciana Porto and Wilza Arantes Ferreira Peres
    Citation: Diabetology & Metabolic Syndrome 2016 8:39
    Content type: Research Published on:

  17. Type 2 diabetes (T2D) and colon cancer (CC) are numbered among the most common diseases in the world. The decreased activity of natural killer (NK) cells previously revealed in both mentioned pathological sta...

    Authors: Paweł Piątkiewicz, Małgorzata Bernat-Karpińska, Tomasz Miłek, Michał Rabijewski and Elżbieta Rosiak
    Citation: Diabetology & Metabolic Syndrome 2016 8:38
    Content type: Research Published on:

  18. To determine whether US and European participants in the Liraglutide Effect and Action in Diabetes: Evaluation of cardiovascular outcome Results (LEADER) trial differ regarding risk factors for cardiovascular ...

    Authors: Guy E. H. M. Rutten, Cees J. Tack, Thomas R. Pieber, Abdurrahman Comlekci, David Dynnes Ørsted, Florian M. M. Baeres, Steven P. Marso and John B. Buse
    Citation: Diabetology & Metabolic Syndrome 2016 8:37
    Content type: Research Published on:

  19. The GetGoal-L-Asia and -S trials were multi-center trials conducted in 4 and 16 countries, respectively including Japan that evaluated the efficacy and safety of lixisenatide add-on treatment vs. placebo among...

    Authors: Hiroaki Seino, Yukiko Onishi, Yusuke Naito and Mitsuhisa Komatsu
    Citation: Diabetology & Metabolic Syndrome 2016 8:36
    Content type: Research Published on:

  20. In 2011, private pharmacies associated to the Brazilian Ministry of Health provided patients with two types of insulin (regular human insulin and isophane insulin or NPH) and three oral antidiabetic medication...

    Authors: João Leopoldo Oliveira Araujo, Mariana Donato Pereira, Cristiane de Cássia Bergamaschi, Fernando de Sá Del Fiol, Luciane Cruz Lopes, Maria Inês de Toledo and Silvio Barberato-Filho
    Citation: Diabetology & Metabolic Syndrome 2016 8:35
    Content type: Research Published on:

  21. Helicobacter pylori (H. pylori) infection is reported to be associated with various extragastrointestinal conditions such as insulin resistance, diabetes mellitus and metabolic syndrom...

    Authors: Wesam Ahmed Nasif, Mohammed Hasan Mukhtar, Mohammed Mahmoud Nour Eldein and Sami Sadagah Ashgar
    Citation: Diabetology & Metabolic Syndrome 2016 8:34
    Content type: Research Published on:

  22. A rare sign of some malignant tumors is a sudden eruption of multiple seborrheic keratoses called Leser-Trélat sign. Overproduction of insulin-like growth factor-2 (IGF2) or its precursor is the main mechanism...

    Authors: Andreia Latanza Gomes Mathez, Debora Moroto, Sergio Atala Dib and Joao Roberto de Sa
    Citation: Diabetology & Metabolic Syndrome 2016 8:33
    Content type: Short report Published on:

  23. Dietary factors are important environmental factors associated with the prevalence of metabolic syndrome (MS). The objective of this study was to assess the habitual nutrient intakes of patients with MS.

    Authors: Aline Tuane Oliveira da Cunha, Hermilla Torres Pereira, Sephora Louyse Silva de Aquino, Cristiane Hermes Sales, Karine Cavalcanti Maurício Sena-Evangelista, Josivan Gomes Lima, Severina Carla Vieira Cunha Lima and Lucia Fatima Campos Pedrosa
    Citation: Diabetology & Metabolic Syndrome 2016 8:32
    Content type: Research Published on:

  24. Distal symmetric polyneuropathy (DSPN) is the most common complication of type 2 diabetes mellitus (T2DM) and the most common form of peripheral neuropathy. DSPN increases the risk of foot ulceration up to sev...

    Authors: Bogdan Timar, Simona Popescu, Romulus Timar, Flavia Baderca, Bogdan Duica, Mihaela Vlad, Codrina Levai, Bogdan Balinisteanu and Mihaela Simu
    Citation: Diabetology & Metabolic Syndrome 2016 8:31
    Content type: Research Published on:

  25. Few studies have assessed the association between health literacy (HL) and healthy lifestyle characteristics among Japanese people, and reports on the association between HL and prevalence of metabolic syndrom...

    Authors: Hirohide Yokokawa, Hiroshi Fukuda, Motoyuki Yuasa, Hironobu Sanada, Teruhiko Hisaoka and Toshio Naito
    Citation: Diabetology & Metabolic Syndrome 2016 8:30
    Content type: Research Published on:

  26. Polymorphisms of vitamin D receptor (VDR) gene have been studied as genetic markers of type 1 diabetes mellitus (T1DM) and some studies have reported associations with autoimmune thyroid disease. The aim of th...

    Authors: Denise Barreto Mory, Monica Andrade Lima Gabbay, Eloá R. Rocco, Teresa Kasamatsu, Felipe Crispim, Walquíria Lopes Miranda and Sérgio Atala Dib
    Citation: Diabetology & Metabolic Syndrome 2016 8:29
    Content type: Research Published on:

  27. Double diabetes (DD) describes both individuals with obesity upon diagnosis of type 1 diabetes and those who have gained weight during follow-up, although cardiovascular risk factors (CVRF) are not well unders...

    Authors: Fernando M. A. Giuffrida, Caroline Bulcão, Roberta A. Cobas, Carlos Antonio Negrato, Marilia B. Gomes and Sergio Atala Dib
    Citation: Diabetology & Metabolic Syndrome 2016 8:28
    Content type: Research Published on:

  28. Metabolic syndrome (MetS) is a cluster of risk factors for type 2 diabetes (Type2 DM) and cardiovascular diseases (CVD), and its prevalence varies based on region, population, and sex. Newborns of women with M...

    Authors: Hamilton dos Prazeres Tavares, Débora Cristina Damasceno Meirelles dos Santos, Joelcio Francisco Abbade, Carlos Antonio Negrato, Paulo Adão de Campos, Iracema Mattos Paranhos Calderon and Marilza Vieira Cunha Rudge
    Citation: Diabetology & Metabolic Syndrome 2016 8:27
    Content type: Research Published on:

  29. This uncontrolled open label study evaluated the effect of dipeptidyl peptidase-4 inhibitors (DPP-4i): sitagliptin and vildagliptin on augmentation index standardized for 75 beats per minute (cAiX@75), blood p...

    Authors: Lea Duvnjak and Kristina Blaslov
    Citation: Diabetology & Metabolic Syndrome 2016 8:26
    Content type: Research Published on:

  30. Studies on diabetic foot and its complications involving a significant and representative sample of patients in South American countries are scarce. The main objective of this study was to acquire clinical and...

    Authors: Maria Candida R. Parisi, Arnaldo Moura Neto, Fabio H. Menezes, Marilia Brito Gomes, Rodrigo Martins Teixeira, José Egídio Paulo de Oliveira, Joana Rodrigues Dantas Pereira, Reine Marie Chaves Fonseca, Lorena Barreto Arruda Guedes, Adriana Costa e Forti, Ana Mayra Andrade de Oliveira, Marta Barreto de Medeiros Nóbrega, Víctor Nóbrega Quintas Colares, Helena Schmid, Otto Henrique Nienov, Marcia Nery…
    Citation: Diabetology & Metabolic Syndrome 2016 8:25
    Content type: Research Published on:

  31. This study aimed to evaluate the markers of insulin resistance and adipokine status in patients with visceral obesity during hospitalization following myocardial infarction (MI) and assess the disturbances of ...

    Authors: Olga Barbarash, Olga Gruzdeva, Evgenya Uchasova, Yulia Dyleva, Ekaterina Belik, Olga Akbasheva, Victoria Karetnikova and Alexander Kokov
    Citation: Diabetology & Metabolic Syndrome 2016 8:24
    Content type: Research Published on:

  32. Berardinelli-Seip congenital lipodystrophy (BSCL) was initially described by Berardinelli in Brazil in 1954 and 5 years later by Seip in Norway. It is an autosomal recessive disease that leads to a generalized...

    Authors: Josivan G. Lima, Lucia Helena C. Nobrega, Natalia Nobrega de Lima, Maria Goretti do Nascimento Santos, Maria F. P. Baracho and Selma Maria Bezerra Jeronimo
    Citation: Diabetology & Metabolic Syndrome 2016 8:23
    Content type: Research Published on:

  33. Sex hormone-binding globulin (SHBG) has been proposed as a biomarker of MetS in children and adults. We aim to determine the associations of SHBG with components of MetS in children from the Middle-East where ...

    Authors: Nasser M. Al-Daghri, Nasiruddin Khan, Shaun Sabico, Omar S. Al-Attas, Majed S. Alokail and Sudhesh Kumar
    Citation: Diabetology & Metabolic Syndrome 2016 8:22
    Content type: Research Published on:

  34. India’s national rural prevalence of type 2 diabetes has quadrupled in the past 25 years. Despite the growing rural burden, few studies have examined putative risk factors and their relationship with glucose i...

    Authors: Matthew Little, Sally Humphries, Kirit Patel, Warren Dodd and Cate Dewey
    Citation: Diabetology & Metabolic Syndrome 2016 8:21
    Content type: Original research Published on:

  36. This cross-sectional analysis evaluated whether determination of E-selectin concentrations could identify deterioration of cardiometabolic risk profile or subclinical atherosclerosis in individuals at low-to-m...

    Authors: Bianca de Almeida-Pititto, Fernando Flexa Ribeiro-Filho, Marcio Sommer Bittencourt, Paulo A. Lotufo, Isabela Bensenor and Sandra R. G. Ferreira
    Citation: Diabetology & Metabolic Syndrome 2016 8:19
    Content type: Research Published on:

  37. Fish consumption may prevent or improve metabolic health. The aim of this study was to identify associations between fish consumption, both fatty and lean, and metabolic syndrome and its components.

    Authors: C. Tørris, M. Molin and M. Cvancarova Småstuen
    Citation: Diabetology & Metabolic Syndrome 2016 8:18
    Content type: Research Published on:

  39. Diabetes therapy that not only lowers glucose levels but also lengthens life spans is required. We previously demonstrated that DPP-4 inhibition ameliorated β cell apoptosis and adipose tissue inflammation in ...

    Authors: Jun Shirakawa, Tomoko Okuyama, Mayu Kyohara, Eiko Yoshida, Yu Togashi, Kazuki Tajima, Shunsuke Yamazaki, Mitsuyo Kaji, Megumi Koganei, Hajime Sasaki and Yasuo Terauchi
    Citation: Diabetology & Metabolic Syndrome 2016 8:16
    Content type: Research Published on:

  40. The 52-week monotherapy with the dipeptidyl peptidase-4 inhibitor sitagliptin and the sulphonylurea glimepiride on early-phase insulin secretion in Japanese patients with type 2 diabetes mellitus (T2DM) is not...

    Authors: Yaeko Kondo, Norio Harada, Akihiro Hamasaki, Shizuka Kaneko, Koichiro Yasuda, Eiichi Ogawa, Shin-ichi Harashima, Hiroko Yoneda, Yoshihito Fujita, Norikazu Kitano, Yoshio Nakamura, Fujio Matsuo, Megumi Shinji, Shiro Hinotsu, Takeo Nakayama and Nobuya Inagaki
    Citation: Diabetology & Metabolic Syndrome 2016 8:15
    Content type: Research Published on:

  41. Metabolic syndrome poses an increased global burden of disease and causes immense financial burden, warranting heightened public health attention. The present study assessed the prevalence and severity of card...

    Authors: Joseph Ravenell, Azizi Seixas, Diana Margot Rosenthal, Olajide Williams, Chinwe Ogedegbe, Mary Ann Sevick, Valerie Newsome and Girardin Jean-Louis
    Citation: Diabetology & Metabolic Syndrome 2016 8:14
    Content type: Research Published on:

  42. The incidence of diabetes mellitus is increasing worldwide, resulting in a global epidemic. The most common type, the type 2 diabetes mellitus, constitutes of 90–95 % of the cases and is characterized by the acti...

    Authors: Carlos Gabriel de Lade, João Carlos Bouzas Marins, Luciana Moreira Lima, Cristiane Junqueira de Carvalho, Robson Bonoto Teixeira, Maicon Rodrigues Albuquerque, Janice Sepúlveda Reis and Paulo Roberto dos Santos Amorim
    Citation: Diabetology & Metabolic Syndrome 2016 8:13
    Content type: Research Published on:

  43. Whereas an increase of neck circumference (NC) had been recently identified as a new independent cardiovascular disease (CVD) and metabolic syndrome risk factor, similar assessments concerning screen-detected ...

    Authors: Mykolay Khalangot, Vitaliy Gurianov, Nadia Okhrimenko, Igor Luzanchuk and Victor Kravchenko
    Citation: Diabetology & Metabolic Syndrome 2016 8:12
    Content type: Research Published on:

  44. Inflammation is an early event in the development of diabetes type 2 (T2D). Cichorium intybus L. (chicory) possesses anti-inflammatory action. We compared the anti-inflammatory aspect of aqueous chicory seed extr...

    Authors: Lotfollah Rezagholizadeh, Yasin Pourfarjam, Azin Nowrouzi, Manuchehr Nakhjavani, Alipasha Meysamie, Nasrin Ziamajidi and Peyman S. Nowrouzi
    Citation: Diabetology & Metabolic Syndrome 2016 8:11
    Content type: Research Published on:

  45. The deep subcutaneous adipose tissue (dSAT) is closely related to the obesity-associated complications similarly to the characteristics of visceral adipose tissue (VAT). However, the association between dSAT a...

    Authors: Se-Hong Kim, Ju-hye Chung, Sang-Wook Song, Won Sang Jung, Yun-Ah Lee and Ha-Na Kim
    Citation: Diabetology & Metabolic Syndrome 2016 8:10
    Content type: Research Published on:

  46. In most individuals, obesity and insulin resistance coexist. However, some individuals have excessive adipose tissue mass but remain insulin sensitive. Moreover, lean individuals can develop acute inflammation...

    Authors: Samuel D. Moscavitch, Hye C. Kang, Rubens A. C. Filho, Evandro T. Mesquita, Hugo C. C. F. Neto and Maria L. G. Rosa
    Citation: Diabetology & Metabolic Syndrome 2016 8:9
    Content type: Research Published on:

  47. The consumption of hyperlipidic and hypercaloric diet is considered a major factor to promote obesity and the consumption of food with antioxidant properties, like Juçara (Euterpe edulis Mart), could be a tool to...

    Authors: L. M. Oyama, F. P. Silva, J. Carnier, D. A. de Miranda, A. B. Santamarina, E. B. Ribeiro, C. M. Oller do Nascimento and V. V. de Rosso
    Citation: Diabetology & Metabolic Syndrome 2016 8:8
    Content type: Research Published on:

  48. The chronic care model (CCM) uses a systematic approach to restructure health care systems. The aim of this systematic review was to examine studies that evaluated different elements of the CCM in patients wi...

    Authors: Deise Regina Baptista, Astrid Wiens, Roberto Pontarolo, Lara Regis, Walleri Christine Torelli Reis and Cassiano Januário Correr
    Citation: Diabetology & Metabolic Syndrome 2016 8:7
    Content type: Review Published on:

  49. Recently, we reported signs of inflammation (raised IL-8, reduced miR-146a) and signs of vascular repair (raised HGF) in the serum of Ecuadorian patients with type 2 diabetes (T2D). In contrast, we found that ...

    Authors: Lucy Baldeón Rojas, Karin Weigelt, Harm de Wit, Behiye Ozcan, Adri van Oudenaren, Fernando Sempértegui, Eric Sijbrands, Laura Grosse, Anton-Jan van Zonneveld, Hemmo A. Drexhage and Pieter J. M. Leenen
    Citation: Diabetology & Metabolic Syndrome 2016 8:6
    Content type: Research Published on:

  50. Deregulation of glycemic and glycated hemoglobin (HbA1) levels accelerate the progression of cardiovascular complications in type 1 diabetes mellitus (T1DM). The aim of this study was to investigate the associati...

    Authors: Sandra de Oliveira, Dahan da Cunha Nascimento, Ramires Alsamir Tibana, Samuel Lima de Oliveira, Ivo Vieira de Sousa Neto, Roberta Kelly Menezes Maciel Falleiros, Leonardo Garcia Miranda, Hermelinda Cordeiro Pedrosa, James Wilfred Navalta, Guilherme Borges Pereira and Jonato Prestes
    Citation: Diabetology & Metabolic Syndrome 2016 8:4
    Content type: Research Published on:

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Diabetology & Metabolic Syndrome

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