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  1. Content type: Research

    Here, we studied the beneficial effects of aerobic exercise on metabolic syndrome components, cognitive performance, brain derived neurotrophic factor (BDNF) and irisin in ovariectomized rats with different se...

    Authors: Parvin Babaei, Samaneh Ghorbani Shirkouhi, Rastegar Hosseini and Bahram Soltani Tehrani

    Citation: Diabetology & Metabolic Syndrome 2017 9:91

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  2. Content type: Review

    Type 2 diabetes mellitus (T2DM) is one of the most common diseases worldwide and insulin insufficiency and insulin resistance are two main metabolic issues connected with it. The dyslipidemia associated with i...

    Authors: Elena Filipova, Katya Uzunova, Krassimir Kalinov and Toni Vekov

    Citation: Diabetology & Metabolic Syndrome 2017 9:90

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  3. Content type: Research

    The purpose of the present study was to assess the validity of continuous metabolic syndrome score (cMetS) for predicting metabolic syndrome (MetS) and to determine the cutoff values in a representative sample...

    Authors: Ramin Heshmat, Motahar Heidari, Hanieh-Sadat Ejtahed, Mohammad Esmaeil Motlagh, Armita Mahdavi-Gorab, Hasan Ziaodini, Majzoubeh Taheri, Gita Shafiee, Shaghayegh Beshtar, Mostafa Qorbani and Roya Kelishadi

    Citation: Diabetology & Metabolic Syndrome 2017 9:89

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  4. Content type: Research

    To describe current prevalence of obesity and related non-communicable diseases (NCDs) in expatriates living in the United Arab Emirates (UAE).

    Authors: Nabil Sulaiman, Salah Elbadawi, Amal Hussein, Salah Abusnana, Abdulrazzag Madani, Maisoon Mairghani, Fatheya Alawadi, Ahmad Sulaiman, Paul Zimmet, Oliver Huse, Jonathan Shaw and Anna Peeters

    Citation: Diabetology & Metabolic Syndrome 2017 9:88

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  5. Content type: Research

    Metabolic syndrome (MetS) is associated with structural and functional vascular abnormalities, which may lead to increased arterial stiffness, more frequent cardiovascular events and higher mortality. However,...

    Authors: Wanda R. P. Lopes-Vicente, Sara Rodrigues, Felipe X. Cepeda, Camila Paixão Jordão, Valéria Costa-Hong, Akothirene C. B. Dutra-Marques, Jefferson C. Carvalho, Maria Janieire N. N. Alves, Luiz A. Bortolotto and Ivani C. Trombetta

    Citation: Diabetology & Metabolic Syndrome 2017 9:87

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  6. Content type: Research

    Previous studies showed that metabolic syndrome is associated with aortic valve calcification (AVC) and poor outcomes in aortic stenosis (AS). However, if these associations change and how body fat impacts the...

    Authors: Jennifer Mancio, Paulo Fonseca, Bruno Figueiredo, Wilson Ferreira, Monica Carvalho, Nuno Ferreira, Pedro Braga, Alberto Rodrigues, Antonio Barros, Ines Falcao-Pires, Adelino Leite-Moreira, Vasco Gama Ribeiro and Nuno Bettencourt

    Citation: Diabetology & Metabolic Syndrome 2017 9:86

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  7. Content type: Review

    Diabetes complications and osteoporotic fractures are two of the most important causes of morbidity and mortality in older patients and share many features including genetic susceptibility, molecular mechanism...

    Authors: Claudia Pinheiro Sanches, Andre Gustavo Daher Vianna and Fellype de Carvalho Barreto

    Citation: Diabetology & Metabolic Syndrome 2017 9:85

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  8. Content type: Research

    DNA methylation is an epigenetic mechanism for regulating the transcription of many genes and has been linked to the development of various diseases. A promising gene to investigate is methylenetetrahydrofolat...

    Authors: Mayara Karla dos Santos Nunes, Alexandre Sérgio Silva, Isabella Wanderley de Queiroga Evangelista, João Modesto Filho, Cecília Neta Alves Pegado Gomes, Rayner Anderson Ferreira do Nascimento, Rafaella Cristhine Pordeus Luna, Maria José de Carvalho Costa, Naila Francis Paulo de Oliveira and Darlene Camati Persuhn

    Citation: Diabetology & Metabolic Syndrome 2017 9:84

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  9. Content type: Research

    There is increasing evidence linking a shift work schedule with various adverse health effects. The present study aimed to examine the relationship between shift work and the metabolic syndrome (MetS) in male ...

    Authors: Yung-Chuan Lu, Chao-Ping Wang, Teng-Hung Yu, I-Ting Tsai, Wei-Chin Hung, I-Cheng Lu, Chia-Chang Hsu, Wei-Hua Tang, Jer-Yiing Houng, Fu-Mei Chung and Mei-Chu Yen Jean

    Citation: Diabetology & Metabolic Syndrome 2017 9:83

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  10. Content type: Research

    Non-alcoholic steatohepatitis (NASH) is highly associated with metabolic syndrome, a major cause of morbidity in the globalized society. The renin–angiotensin system (RAS) influences hepatic fatty acid metabol...

    Authors: F. N. Ramalho, S. C. Sanches, M. C. Foss, M. J. Augusto, D. M. Silva, A. M. Oliveira and L. N. Ramalho

    Citation: Diabetology & Metabolic Syndrome 2017 9:82

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  11. Content type: Research

    During the prediabetic development, the changes in β-cell function and tissue-specific insulin resistance have been described. However, there are conflicting views in insulin secretory capacity between early c...

    Authors: Meng-Chieh Hsu, Mu-En Wang, Yi-Fan Jiang, Hung-Chang Liu, Yi-Chen Chen and Chih-Hsien Chiu

    Citation: Diabetology & Metabolic Syndrome 2017 9:81

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  12. Content type: Research

    Berardinelli-Seip Congenital Lipodystrophy (BSCL) is a rare disease characterized by the almost complete absence of adipose tissue. Although a large number of BSCL cases was previously identified in Rio Grande...

    Authors: Lázaro Batista de Azevedo Medeiros, Verônica Kristina Cândido Dantas, Aquiles Sales Craveiro Sarmento, Lucymara Fassarella Agnez-Lima, Adriana Lúcia Meireles, Thaiza Teixeira Xavier Nobre, Josivan Gomes de Lima and Julliane Tamara Araújo de Melo Campos

    Citation: Diabetology & Metabolic Syndrome 2017 9:80

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  13. Content type: Research

    Diabetes is a risk factor for peripheral, coronary, and cerebrovascular disease. In contrast, results also indicate that patients with diabetes have reduced prevalence of aortic aneurysms, although the mechani...

    Authors: Camilla Krizhanovskii, Stelia Ntika, Christian Olsson, Per Eriksson and Anders Franco-Cereceda

    Citation: Diabetology & Metabolic Syndrome 2017 9:79

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  14. Content type: Research

    It is unknown whether canagliflozin, a selective sodium glucose co-transporter 2 inhibitor, reduces epicardial adipose tissue (EAT) thickness, which is associated with insulin resistance and is a risk factor f...

    Authors: Shusuke Yagi, Yukina Hirata, Takayuki Ise, Kenya Kusunose, Hirotsugu Yamada, Daiju Fukuda, Hotimah Masdan Salim, Gulinu Maimaituxun, Susumu Nishio, Yuriko Takagawa, Saori Hama, Tomomi Matsuura, Koji Yamaguchi, Takeshi Tobiume, Takeshi Soeki, Tetsuzo Wakatsuki…

    Citation: Diabetology & Metabolic Syndrome 2017 9:78

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  15. Content type: Research

    Although previous studies have established a close relationship between caloric intake and metabolic syndrome, there is limited research exploring the impact of meal frequency adjusted by caloric intake on met...

    Authors: Chan-Hee Jung, Ji Sung Lee, Hee Jung Ahn, Jin-Sun Choi, Min Young Noh, Ji Jeung Lee, Eun Young Lee, Jeong Hyun Lim, Young Ran Lee, So Yoon Yoon, Chong Hwa Kim, Dong-Hyeok Cho, Young Sik Choi and Kyung Mook Choi

    Citation: Diabetology & Metabolic Syndrome 2017 9:77

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  16. Content type: Research

    Obesity, metabolic syndrome (MetS), and diabetes are frequent in surgical populations and can enhance susceptibility to postoperative surgical site infections. Reduced neutrophil function has been linked with ...

    Authors: Ingrid Lea Scully, Lisa Kristin McNeil, Sudam Pathirana, Christine Lee Singer, Yongdong Liu, Stanley Mullen, Douglas Girgenti, Alejandra Gurtman, Michael W. Pride, Kathrin Ute Jansen, Paul L. Huang and Annaliesa S. Anderson

    Citation: Diabetology & Metabolic Syndrome 2017 9:76

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  17. Content type: Research

    Surfactant protein D (SP-D) is a member of the collectin family and is an important component of the pulmonary innate host defense. To find the relationship between exercise training and SP-D in diabetes, we e...

    Authors: Sajjad Rezaei, Mahdieh Molanouri Shamsi, Mehdi Mahdavi, Azadeh Jamali, Jonato Prestes, Ramires Alsamir Tibana, James Wilfred Navalta and Fabrício Azevedo Voltarelli

    Citation: Diabetology & Metabolic Syndrome 2017 9:74

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  18. Content type: Research

    Recently, we reported that toll-like receptor (TLR)2 and TLR4 localized on the glomerular endothelium in the glomeruli of streptozotocin (STZ)-induced type 1 diabetic mice and high fat diet feed-induced type 2...

    Authors: Koichiro Kajiwara, Shunsuke Takata, Thao T. To, Kenyo Takara, Yuji Hatakeyama, Sachio Tamaoki, Richard Peters Darveau, Hiroyuki Ishikawa and Yoshihiko Sawa

    Citation: Diabetology & Metabolic Syndrome 2017 9:73

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  19. Content type: Research

    In recent years, obesity has become one of the most important public health problems in the world, with a growing prevalence in both developed and developing countries. Recent studies show that sleep disturban...

    Authors: Eduardo Araujo Perez, Luis Vicente Franco Oliveira, Wilson Rodrigues Freitas Jr., Carlos Alberto Malheiros, Elias Jirjoss Ilias, Anderson Soares Silva, Jessica Julioti Urbano, Patricia Clemente Oliveira, Felipe X. Cepeda, Luciana M. M. Sampaio, Ivani C. Trombetta, Humberto Delle, Daniel Gianella Neto, Sergio Roberto Nacif and Roberto Stirbulov

    Citation: Diabetology & Metabolic Syndrome 2017 9:72

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  20. Content type: Research

    Evidences support the benefits of moderate- to high-intensity statins for patients with acute myocardial infarction (AMI) except for those with type 2 diabetes mellitus (T2DM) on dialysis after AMI. This study...

    Authors: Yan-Rong Li, Sung-Sheng Tsai, Yu-Sheng Lin, Chang-Min Chung, Szu-Tah Chen, Jui-Hung Sun, Miaw-Jene Liou and Tien-Hsing Chen

    Citation: Diabetology & Metabolic Syndrome 2017 9:71

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  21. Content type: Erratum

    Upon publication of the original article [1], it was noticed that the Ref. [32] was incorrectly given as [32]: Allan GM, Nouri F, Korownyk C, Kolber MR, Vandermeer B, McCormack J. Agreement among cardiovascular d...

    Authors: Marcello Casaccia Bertoluci and Viviane Zorzanelli Rocha

    Citation: Diabetology & Metabolic Syndrome 2017 9:70

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    The original article was published in Diabetology & Metabolic Syndrome 2017 9:25

  22. Content type: Research

    Reduced insulin sensitivity not only contributes to the pathogenesis of type 2 diabetes but is also linked to multiple metabolic risk factors and cardiovascular diseases (CVD). A prolonged heart rate-corrected...

    Authors: Xiao-hua Yang, Jian-bin Su, Xiu-lin Zhang, Li-hua Zhao, Feng Xu, Xue-qin Wang and Xing-bo Cheng

    Citation: Diabetology & Metabolic Syndrome 2017 9:69

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  23. Content type: Research

    Albuminuria is generally accepted as a sensitive marker of diabetic nephropathy but has limitations in predicting its progression. The aim of this study was to evaluate the use of nonalbumin proteinuria in add...

    Authors: Jong Ho Kim, Seo Young Oh, Eun Heui Kim, Min Jin Lee, Yun Kyung Jeon, Bo Hyun Kim, Jin Mi Kim, Yong Ki Kim, Sang Soo Kim and In Joo Kim

    Citation: Diabetology & Metabolic Syndrome 2017 9:68

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  24. Content type: Research

    Interleukin-6 (IL-6) plays a central role in atherosclerosis and inflammation. It may improve risk prediction in patients at intermediate cardiovascular risk.

    Authors: Marco V. Wainstein, Márcio Mossmann, Gustavo N. Araujo, Sandro C. Gonçalves, Gabriela L. Gravina, Marlei Sangalli, Francine Veadrigo, Roselene Matte, Rejane Reich, Fernanda G. Costa, Michael Andrades, Antônio Marcos V. da Silva and Marcello C. Bertoluci

    Citation: Diabetology & Metabolic Syndrome 2017 9:67

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  25. Content type: Research

    Worldwide there is an increased prevalence of metabolic syndrome mainly due to life-style modifications, and Africans are not saved of this situation. Many markers have been studied to predict the risk of this...

    Authors: Clarisse Noël A. Ayina, Francky Teddy A. Endomba, Samuel Honoré Mandengue, Jean Jacques N. Noubiap, Laurent Serge Etoundi Ngoa, Philippe Boudou, Jean-François Gautier, Jean Claude Mbanya and Eugene Sobngwi

    Citation: Diabetology & Metabolic Syndrome 2017 9:66

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  26. Content type: Research

    While the association of the prevalence of non-alcoholic fatty liver disease (NAFLD) with impaired glucose metabolism has been reported, the factors influencing glucose tolerance in NAFLD remain to be clarified.

    Authors: Satoko Ohmi, Masafumi Ono, Hiroshi Takata, Seiki Hirano, Shogo Funakoshi, Yuichi Nishi, Kumiko Yoshimura, Eri Amano, Yoshio Terada, Toshiji Saibara and Shimpei Fujimoto

    Citation: Diabetology & Metabolic Syndrome 2017 9:65

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  27. Content type: Research

    We investigated the influence of aerobic capacity on the improvement in glycemic control achieved by long-term aerobic exercise in type 2 diabetes.

    Authors: Hideki Nojima, Masayasu Yoneda, Hiroshi Watanabe, Kiminori Yamane, Yoshihiro Kitahara, Kiyokazu Sekikawa, Hideya Yamamoto, Akihito Yokoyama, Noboru Hattori and Nobuoki Kohno

    Citation: Diabetology & Metabolic Syndrome 2017 9:63

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  28. Content type: Research

    To describe the abundance of major phyla and some genera in the gut microbiota of individuals according to dietary habits and examine their associations with inflammatory markers, insulin resistance, and cardi...

    Authors: Ana Carolina Franco-de-Moraes, Bianca de Almeida-Pititto, Gabriel da Rocha Fernandes, Everton Padilha Gomes, Alexandre da Costa Pereira and Sandra Roberta G. Ferreira

    Citation: Diabetology & Metabolic Syndrome 2017 9:62

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  29. Content type: Short report

    Diabetes related distress is common in type 1 diabetes patients (T1D). High levels of diabetes distress are related to poor metabolic control. An instrument to evaluate diabetes distress in T1D patients is “type ...

    Authors: M. S. V. M. Silveira, T. G. Bovi, P. F. Oliveira, E. J. Pavin and L. Fisher

    Citation: Diabetology & Metabolic Syndrome 2017 9:61

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  30. Content type: Research

    Inhibitors of sodium-glucose co-transporter 2 (SGLT2) have immediate glucose-lowering effects by promoting urinary glucose excretion, without altering insulin level. Only a few studies have evaluated blood glu...

    Authors: Keiichi Torimoto, Yosuke Okada, Kenji Koikawa and Yoshiya Tanaka

    Citation: Diabetology & Metabolic Syndrome 2017 9:60

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  31. Content type: Review

    Diabetes is a complex condition with a variety of causes and pathophysiologies. The current single target approach has not provided ideal clinical outcomes for the treatment of the disease and its complication...

    Authors: Ramesh C. Gupta, Dennis Chang, Srinivas Nammi, Alan Bensoussan, Kellie Bilinski and Basil D. Roufogalis

    Citation: Diabetology & Metabolic Syndrome 2017 9:59

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  32. Content type: Research

    This study aimed to determine self-monitoring practices, awareness to dietary modifications and barriers to medication adherence among physically disabled type 2 diabetes mellitus patients.

    Authors: Syed Wasif Gillani, Syed Azhar Syed Sulaiman, Mohi Iqbal Mohammad Abdul and Sherif Y. Saad

    Citation: Diabetology & Metabolic Syndrome 2017 9:58

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  33. Content type: Review

    Type 2 diabetes and its management affect the patient and the close family potentially causing either psychological distress or increased sense of responsibility and collaboration in these families. Interactio...

    Authors: Birgitte B. Bennich, Michael E. Røder, Dorthe Overgaard, Ingrid Egerod, Lene Munch, Filip K. Knop, Tina Vilsbøll and Hanne Konradsen

    Citation: Diabetology & Metabolic Syndrome 2017 9:57

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  34. Content type: Research

    Diabetic cardiomyopathy (DCM) is a serious cardiac dysfunction induced by changes in the structure and contractility of the myocardium that are initiated in part by alterations in energy substrates. The underl...

    Authors: Shifen Dong, Rong Zhang, Yaoyue Liang, Jiachen Shi, Jiajia Li, Fei Shang, Xuezhou Mao and Jianning Sun

    Citation: Diabetology & Metabolic Syndrome 2017 9:56

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  35. Content type: Research

    Dipeptidyl peptidase-4 (DPP-4) inhibitors and sodium–glucose co-transporter 2 (SGLT2) inhibitors improve hyperglycemia, and the usefulness of co-administration of DPP-4 inhibitors and insulin therapy has been ...

    Authors: Hiroshi Nomoto, Hideaki Miyoshi, Hajime Sugawara, Kota Ono, Shingo Yanagiya, Mayuko Oita, Akinobu Nakamura and Tatsuya Atsumi

    Citation: Diabetology & Metabolic Syndrome 2017 9:54

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  36. Content type: Review

    Since the first position statement on diabetes and cardiovascular prevention published in 2014 by the Brazilian Diabetes Society, the current view on primary and secondary prevention in diabetes has evolved as...

    Authors: Marcello Casaccia Bertoluci, Rodrigo Oliveira Moreira, André Faludi, Maria Cristina Izar, Beatriz D. Schaan, Cynthia Melissa Valerio, Marcelo Chiara Bertolami, Ana Paula Chacra, Marcus Vinicius Bolivar Malachias, Sérgio Vencio, José Francisco Kerr Saraiva, Roberto Betti, Luiz Turatti, Francisco Antonio Helfenstein Fonseca, Henrique Tria Bianco, Marta Sulzbach…

    Citation: Diabetology & Metabolic Syndrome 2017 9:53

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  37. Content type: Research

    The global prevalence of type 2 diabetes is considerable. To avoid or delay its chronic complications, patients with type 2 diabetes should improve blood glucose management by adapting their life style. This i...

    Authors: Marie-Christine Turnin, Solène Schirr-Bonnans, Jacques Martini, Jean-Christophe Buisson, Soumia Taoui, Marie-Christine Chauchard, Nadège Costa, Benoît Lepage, Laurent Molinier and Hélène Hanaire

    Citation: Diabetology & Metabolic Syndrome 2017 9:52

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  38. Content type: Short report

    To translate and validate the instrument Diabetes Self-Management Profile (DSMP)—Conventional and Flexible Regimens into Brazilian Portuguese language in order to evaluate the quality of diabetes self-manageme...

    Authors: Caroline Gouveia Buff Passone, Lygia Spassapan Oliveira Esteves, Roberta Dias Savoldelli, Michael A. Harris, Durval Damiani and Thais Della Manna

    Citation: Diabetology & Metabolic Syndrome 2017 9:51

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  39. Content type: Short report

    Insulin resistance and insulin deficiency are the cardinal defects in the pathogenesis of type 2 diabetes mellitus (T2DM). Despite the plethora of anti-diabetic medications, drugs specifically targeting the β-...

    Authors: Shobhit Bhansali, Pinaki Dutta, Mukesh Kumar Yadav, Ashish Jain, Sunder Mudaliar, Meredith Hawkins, Anura V. Kurpad, Deepak Pahwa, Ashok Kumar Yadav, Ratti Ram Sharma, Vivekanand Jha, Neelam Marwaha, Shipra Bhansali and Anil Bhansali

    Citation: Diabetology & Metabolic Syndrome 2017 9:50

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  40. Content type: Research

    Adiponectin has been implicated in metabolic syndrome (MetS) and arterial stiffness (AS). We aim to determine the relationship between serum adiponectin concentration as well as peripheral AS in hypertensive p...

    Authors: Ming-Chun Chen, Chung-Jen Lee, Chiu-Fen Yang, Yu-Chih Chen, Ji-Hung Wang and Bang-Gee Hsu

    Citation: Diabetology & Metabolic Syndrome 2017 9:49

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  41. Content type: Short report

    Type 1 diabetes mellitus (T1DM) is one of the most common pediatric diseases and its incidence is rising in many countries. Recently, it has been shown that metabolites other than glucose play an important rol...

    Authors: Liene Bervoets, Guy Massa, Wanda Guedens, Evelyne Louis, Jean-Paul Noben and Peter Adriaensens

    Citation: Diabetology & Metabolic Syndrome 2017 9:48

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  42. Content type: Research

    Type 2 diabetes is a major healthcare problem. Glucose-, lipid-, and blood pressure-lowering strategies decrease the risk of micro- and macrovascular complications. However, a substantial residual risk remains...

    Authors: Thijs T. W. van Herpt, Roosmarijn F. H. Lemmers, Mandy van Hoek, Janneke G. Langendonk, Ronald J. Erdtsieck, Bert Bravenboer, Annelies Lucas, Monique T. Mulder, Harm R. Haak, Aloysius G. Lieverse and Eric J. G. Sijbrands

    Citation: Diabetology & Metabolic Syndrome 2017 9:47

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  43. Content type: Research

    Type 2 diabetes mellitus (T2DM) is a complex disease, particularly in a continental country like Brazil. We attempted to understand and evaluate the perceptions and routines of Brazilians with T2DM and physici...

    Authors: Sérgio Vencio, Päivi M. Paldánius, Matthias Blüher, Daniel Giannella-Neto, Rafael Caiado-Vencio and W. David Strain

    Citation: Diabetology & Metabolic Syndrome 2017 9:46

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  44. Content type: Research

    Ten to forty percent of nonalcoholic steatohepatitis (NASH) and HCV-related chronic liver disease (CLD-C) patients have antinuclear antibodies (ANAs). However, the relationship between autoimmune response and ...

    Authors: Takashi Himoto, Koji Fujita, Takako Nomura, Joji Tani, Asahiro Morishita, Hirohito Yoneyama, Reiji Haba and Tsutomu Masaki

    Citation: Diabetology & Metabolic Syndrome 2017 9:45

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  45. Content type: Research

    Type 2 diabetes (T2D) is associated with reduced numbers and impaired function of circulating angiogenic cells (CAC) which contributes to the progression of atherosclerosis and microvascular disease. Previous ...

    Authors: Behiye Özcan, Pieter J. M. Leenen, Patric J. D. Delhanty, Lucy Y. Baldéon-Rojas, Sebastian J. Neggers and Aart Jan van der Lely

    Citation: Diabetology & Metabolic Syndrome 2017 9:43

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  46. Content type: Research

    The metabolic syndrome (MetS) comprises several cardiometabolic risk factors associated with increased risk for both type 2 diabetes and cardiovascular disease. Skin autofluorescence (SAF), a non-invasive biom...

    Authors: Robert P. van Waateringe, Sandra N. Slagter, Andre P. van Beek, Melanie M. van der Klauw, Jana V. van Vliet-Ostaptchouk, Reindert Graaff, Andrew D. Paterson, Helen L. Lutgers and Bruce H. R. Wolffenbuttel

    Citation: Diabetology & Metabolic Syndrome 2017 9:42

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