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  1. Metabolic syndrome (MetS) is a cluster of conditions that occur together, increasing the risk of heart disease, stroke and diabetes. Since pathways implicated in different diseases reveal surprising insights i...

    Authors: Vânia Gaio, Baltazar Nunes, Aida Fernandes, Francisco Mendonça, Filomena Horta Correia, Álvaro Beleza, Ana Paula Gil, Mafalda Bourbon, Astrid Vicente, Carlos Matias Dias and Marta Barreto da Silva
    Citation: Diabetology & Metabolic Syndrome 2014 6:23
    Content type: Research Published on:

  2. Diabetes mellitus (DM) and intermittent claudication (IC) are frequently associated health conditions. Our hypothesis is that the nature, severity and quality of life (QoL) of patients with IC and DM are worse...

    Authors: Francisco S Lozano, José R González-Porras, José R March, José M Lobos, Eduardo Carrasco and Eduardo Ros
    Citation: Diabetology & Metabolic Syndrome 2014 6:21
    Content type: Research Published on:

  3. A dd-on L antus® to O ral H ypoglycemic A gents (ALOHA), an observational, non-interventional, 24-week post-marketing surveillance study in Japanese patients with type 2 diabetes (T2DM) having uncontrolled glycem...

    Authors: Masato Odawara, Takashi Kadowaki and Yusuke Naito
    Citation: Diabetology & Metabolic Syndrome 2014 6:20
    Content type: Research Published on:

  4. The relationship of saliva with plasma protein levels makes saliva an attractive diagnostic tool. Plasma levels of adiponectin and leptin in healthy individuals or diabetes mellitus patients have been previous...

    Authors: Supanee Thanakun, Hisashi Watanabe, Sroisiri Thaweboon and Yuichi Izumi
    Citation: Diabetology & Metabolic Syndrome 2014 6:19
    Content type: Research Published on:

  5. Obesity, a critical component of metabolic syndrome (MetS), is associated with depression. Deficiency of brain-derived neurotrophic factor (BDNF) is involved in the mechanism of depression. We hypothesized tha...

    Authors: I-Te Lee, Chia-Po Fu, Wen-Jane Lee, Kae-Woei Liang, Shih-Yi Lin, Chu-Jen Wan and Wayne Huey-Herng Sheu
    Citation: Diabetology & Metabolic Syndrome 2014 6:18
    Content type: Research Published on:

  6. About 30% of patients with type 2 diabetes mellitus develop clinically overt nephropathy. Hyperglycemia is necessary, but not sufficient, to cause the renal damage that leads to kidney failure. Diabetic nephro...

    Authors: Bruno Schmidt Dellamea, Cristiane Bauermann Leitão, Rogério Friedman and Luis Henrique Canani
    Citation: Diabetology & Metabolic Syndrome 2014 6:17
    Content type: Review Published on:

  7. Glycated hemoglobin (A1C) and Fasting Plasma Glucose (FPG) are the two monitoring blood glucose tests most frequently used. However, both methods are shown to be insensitive to detect glycemic variations in sh...

    Authors: Bruno P Moura, Paulo RS Amorim, Bruno PP Silva, Sylvia CC Franceschini, Janice S Reis and João CB Marins
    Citation: Diabetology & Metabolic Syndrome 2014 6:16
    Content type: Research Published on:

  8. Serum N-terminal pro-B-type natriuretic peptide (NT-proBNP) was lower in the general population with metabolic syndrome (MetS). The aim of this study was to evaluate the relationship between MetS and fasting s...

    Authors: Ji-Hung Wang, Chung-Jen Lee, Jen-Che Hsieh, Yu-Chih Chen and Bang-Gee Hsu
    Citation: Diabetology & Metabolic Syndrome 2014 6:15
    Content type: Research Published on:

  10. Individuals with diabetes may develop cardiac autonomic dysfunction that may be evaluated by heart rate variability (HRV). The aim was evaluated heart rate variability (HRV) of individuals with type 2 diabetes...

    Authors: Sílvia CG Moura-Tonello, Anielle CM Takahashi, Cristina O Francisco, Sérgio LB Lopes, Adriano M Del Vale, Audrey Borghi-Silva, Angela MO Leal, Nicola Montano, Alberto Porta and Aparecida M Catai
    Citation: Diabetology & Metabolic Syndrome 2014 6:13
    Content type: Research Published on:

  12. Waist circumference (WC) is used as a risk assessment for metabolic syndrome, diabetes, and cardiovascular disease (CVD). WC consists of visceral fat area (VFA), subcutaneous fat area (SFA), muscle, intramuscu...

    Authors: Yumi Matsushita, Toru Nakagawa, Michihiro Shinohara, Shuichiro Yamamoto, Yoshihiko Takahashi, Tetsuya Mizoue, Tetsuji Yokoyama and Mitsuhiko Noda
    Citation: Diabetology & Metabolic Syndrome 2014 6:11
    Content type: Research Published on:

  13. The Editors of Diabetology and Metabolic Syndrome would like to thank all our reviewers who have contributed to the journal in Volume 5 (2013).

    Authors: Daniel Giannella-Neto and Marilia de Brito Gomes
    Citation: Diabetology & Metabolic Syndrome 2014 6:9
    Content type: Reviewer acknowledgement Published on:

  14. The obese Zücker diabetic fatty male rat (ZDF:Gmi™-fa) is an animal model of type II diabetes associated with obesity and related metabolic disturbances like dyslipidaemia and diabetic nephropathy. In addition...

    Authors: Eduardo J Lezcano, Pablo Iñigo, Ana M Larraga, Cristina Barranquero, Ignacio Gimenez and Jesús Osada
    Citation: Diabetology & Metabolic Syndrome 2014 6:10
    Content type: Research Published on:

  15. The etiology of the metabolic syndrome is complex, and is determined by the interplay of both genetic and environmental factors. The present study was designed to identify genes and proteins in the adipose tis...

    Authors: Jie Chang, Shinji Oikawa, Hitoshi Iwahashi, Emiko Kitagawa, Ichiro Takeuchi, Masao Yuda, Chieko Aoki, Yoshiji Yamada, Gaku Ichihara, Masashi Kato and Sahoko Ichihara
    Citation: Diabetology & Metabolic Syndrome 2014 6:8
    Content type: Research Published on:

  16. Vitamin D deficiency has been linked to several cardiovascular risk factors but information regarding vitamin D concentrations in familial combined hyperlipidemia (FCHL) is lacking. Our objective was to examin...

    Authors: Inka Miñambres, Jose Luis Sánchez-Quesada, Joan Sánchez-Hernández, Jose Rodríguez, Alberto de Leiva and Antonio Pérez
    Citation: Diabetology & Metabolic Syndrome 2014 6:7
    Content type: Research Published on:

  17. Metabolic syndrome is a cluster of metabolic risk factors including dyslipidemia, impaired glucose tolerance, hypertension and central obesity. BDNF (Brain-derived neurotrophic factor) and leptin have been imp...

    Authors: Kanjana Suriyaprom, Rungsunn Tungtrongchitr and Kittisak Thawnasom
    Citation: Diabetology & Metabolic Syndrome 2014 6:6
    Content type: Research Published on:

  18. Type 2 diabetes mellitus patients with an acute coronary event (ACE) experience decreased quality of life and increased distress. According to the American Diabetes Association, discharge from the hospital is ...

    Authors: Marise J Kasteleyn, Kees J Gorter, Rebecca K Stellato, Mieke Rijken, Giel Nijpels and Guy EHM Rutten
    Citation: Diabetology & Metabolic Syndrome 2014 6:5
    Content type: Research Published on:

  19. Dysregulation of omentin-1, a beneficial adipokine, is thought to play a role in the development of type 2 diabetes and cardiovascular disease. The objective of this study was to evaluate the relationship betw...

    Authors: Anh Vu, Maha S Sidhom, Brooke C Bredbeck, Lisa A Kosmiski and Christina L Aquilante
    Citation: Diabetology & Metabolic Syndrome 2014 6:4
    Content type: Research Published on:

  20. Glucocorticoid excess is commonly associated with diabetogenic effects, including insulin resistance and glucose intolerance. The effects of the long-term glucagon-like peptide 1 receptor agonist treatment on ...

    Authors: Liselotte Fransson, Cristiane dos Santos, Petra Wolbert, Åke Sjöholm, Alex Rafacho and Henrik Ortsäter
    Citation: Diabetology & Metabolic Syndrome 2014 6:3
    Content type: Research Published on:

  21. To study mortality rates among patients with diabetes and concomitant atrial fibrillation (AF), prescribed different cardiovascular drugs in primary health care.

    Authors: Per Wändell, Axel C Carlsson, Jan Sundquist, Sven-Erik Johansson, Matteo Bottai and Kristina Sundquist
    Citation: Diabetology & Metabolic Syndrome 2014 6:2
    Content type: Research Published on:

  22. Metabolic syndrome (MS) is a condition associated with obesity that identifies individuals with increased cardiovascular risk. Gastric bypass improves several MS components, such as glucose, lipid metabolism a...

    Authors: Mário Nora, Marta Guimarães, Rui Almeida, Paulo Martins, Gil Gonçalves, Mariana Santos, Tiago Morais, Cláudia Freitas and Mariana P Monteiro
    Citation: Diabetology & Metabolic Syndrome 2014 6:1
    Content type: Research Published on:

  23. Regional differences in the clinical care of Type 1 diabetes (T1D) in Brazil have been recently described. This study aimed to estimate the costs of T1D from the public health care system’s perspective across ...

    Authors: Roberta Arnoldi Cobas, Marcos Bosi Ferraz, Alessandra Saldanha de Mattos Matheus, Lucianne Righeti Monteiro Tannus, Aline Tiemi Kano Silva, Luiz Antonio de Araujo, Carlos Antonio Negrato, Sérgio Atala Dib and Marilia Brito Gomes
    Citation: Diabetology & Metabolic Syndrome 2013 5:83
    Content type: Research Published on:

  24. Several studies point to a correlation between obesity and the severity of depressive and anxiety symptoms in children and adults, but there are still some controversial points about this association. The aim ...

    Authors: Erika P Guedes, Eduardo Madeira, Thiago T Mafort, Miguel Madeira, Rodrigo O Moreira, Laura MC Mendonça, Amélio F Godoy-Matos, Agnaldo J Lopes and Maria Lucia F Farias
    Citation: Diabetology & Metabolic Syndrome 2013 5:82
    Content type: Research Published on:

  25. This study aimed at investigating whether impaired fasting glucose (IFG) is an independent risk factor for incident hypertension among middle-aged Japanese subjects with optimal blood pressure (OBP).

    Authors: Masaaki Morio, Machiko Inoue, Kazuo Inoue and Kimihiko Akimoto
    Citation: Diabetology & Metabolic Syndrome 2013 5:81
    Content type: Short report Published on:

  26. The use of diuretics for hypertension has been associated with unfavorable changes in cardiovascular risk factors, such as uric acid and glucose tolerance, though the findings in the literature are contradictory.

    Authors: Silvio Buscemi, Antonio Nicolucci, Giuseppe Lucisano, Fabio Galvano, Giuseppe Grosso, Fatima M Massenti, Emanuele Amodio, Alice Bonura, Delia Sprini and Giovam B Rini
    Citation: Diabetology & Metabolic Syndrome 2013 5:80
    Content type: Research Published on:

  27. Peroxisome proliferator-activated receptor gamma (PPARγ) has direct and indirect function in adipokines production process. We aimed to assess the possible influence of circulating PPARγ on relative risk of me...

    Authors: Khadijeh Mirzaei, Arash Hossein-nezhad, Seyed Ali Keshavarz, Fariba Koohdani, Ali Akbar Saboor-Yaraghi, Saeed Hosseini, Mohammad Reza Eshraghian and Mahmoud Djalali
    Citation: Diabetology & Metabolic Syndrome 2013 5:79
    Content type: Research Published on:

  29. A residual risk of cardiovascular disease tends to persist despite standard prevention therapy with statins. This may stem partly from increased oxidized low-density lipoprotein (LDL) levels. However, how oxid...

    Authors: Morihiro Matsuda, Ritsu Tamura, Kotaro Kanno, Takatsugu Segawa, Haruyuki Kinoshita, Orie Nishimoto, Hirohiko Nishiyama and Toshiharu Kawamoto
    Citation: Diabetology & Metabolic Syndrome 2013 5:77
    Content type: Research Published on:

  30. Diabetes mellitus, as a risk factor for endometrial cancer (EC), causes an increase in insulin and IGF-1 concentrations in the blood serum. The increase in insulin and IGF-1 are considered mitogenic factors co...

    Authors: Anna Markowska, Monika Pawałowska, Violetta Filas, Konstanty Korski, Marian Gryboś, Stefan Sajdak, Anita Olejek, Wiesława Bednarek, Beata Śpiewankiewicz, Jolanta Lubin and Janina Markowska
    Citation: Diabetology & Metabolic Syndrome 2013 5:76
    Content type: Research Published on:

  31. Several studies highlight curcumin’s benefit as a hypoglycemic agent, however; a limited number of reports present the importance of curcumin in improvement of pancreatic islets in diabetes. The aim of the pre...

    Authors: Mohamed T Abdel Aziz, Mohamed F El-Asmar, Ameen M Rezq, Soheir M Mahfouz, Mohamed A Wassef, Hanan H Fouad, Hanan H Ahmed and Fatma M Taha
    Citation: Diabetology & Metabolic Syndrome 2013 5:75
    Content type: Research Published on:

  32. Body mass index (BMI) and waist circumference (WC) are the most used anthropometric measures to identify obesity. While BMI is considered to be a simple and accurate estimate of general adiposity, WC is an alt...

    Authors: Márcio Weissheimer Lauria, Lívia Maria Pinheiro Moreira, George Luiz Lins Machado-Coelho, Raimundo Marques do Nascimento Neto, Maria Marta Sarquis Soares and Adauto Versiani Ramos
    Citation: Diabetology & Metabolic Syndrome 2013 5:74
    Content type: Research Published on:

  33. The purpose of this study was to explore the extent of associations of cardiovascular autonomic neuropathy (CAN) with metabolic syndrome (MetS) and resting heart reate (HR), and to evaluate the predictive valu...

    Authors: Yu Lu, Zi-Hui Tang, Fangfang Zeng, Yiming Li and Linuo Zhou
    Citation: Diabetology & Metabolic Syndrome 2013 5:73
    Content type: Research Published on:

  34. Abdominal obesity and insulin resistance (IR) place youth at higher risk for premature cardiovascular disease (CVD), but the underlying mechanisms are not clear. In adults, abdominal obesity and IR contribute ...

    Authors: Justin R Ryder, Sonia Vega-López, Constantine S Djedjos and Gabriel Q Shaibi
    Citation: Diabetology & Metabolic Syndrome 2013 5:72
    Content type: Short report Published on:

  35. The aim of this study is to assess the association between the degree of insulin resistance and the different components of the metabolic syndrome among Chinese children and adolescents. Moreover, to determine...

    Authors: Jinhua Yin, Ming Li, Lu Xu, Ying Wang, Hong Cheng, Xiaoyuan Zhao and Jie Mi
    Citation: Diabetology & Metabolic Syndrome 2013 5:71
    Content type: Research Published on:

  36. Metformin treatment has been the most recommended monotherapy of type 2 diabetes mellitus (T2DM) for decades but is challenged by new antidiabetic drugs. This study conducted a meta-analysis of randomized cont...

    Authors: Hongmei Zhu, Shuang Zhu, Xiuqian Zhang, Yang Guo, Yunzhen Shi, Zhimin Chen and Siu-wai Leung
    Citation: Diabetology & Metabolic Syndrome 2013 5:70
    Content type: Research Published on:

  39. It is unclear if the sugar intake may affect metabolic parameters in individuals with type 1 diabetes. Therefore, the purpose of this study was to evaluate the effects of sucrose intake in glycemic, lipemic, a...

    Authors: Débora Lopes Souto, Lenita Zajdenverg, Melanie Rodacki and Eliane Lopes Rosado
    Citation: Diabetology & Metabolic Syndrome 2013 5:67
    Content type: Research Published on:

  40. There is lack of consensus concerning the best screening strategy for gestational diabetes (GDM). The aim of our survey was therefore to investigate attitudes and practices of all obstetrical centers in the no...

    Authors: Katrien Benhalima, Paul Van Crombrugge, Roland Devlieger, Johan Verhaeghe, Ann Verhaegen, Luc De Catte and Chantal Mathieu
    Citation: Diabetology & Metabolic Syndrome 2013 5:66
    Content type: Research Published on:

  41. The purpose of this study is to investigate the association of metabolic syndrome (MS) and its components with the risk of impaired glucose tolerance (IGT) in high risk urban professionals. The goal is to impr...

    Authors: Ping Zeng, Xuefeng Zhu, Yi Zhang, Sinan Wu, Jun Dong, Tiemei Zhang and Shu Wang
    Citation: Diabetology & Metabolic Syndrome 2013 5:65
    Content type: Research Published on:

  42. Oral health complications in diabetes and hypertension include decreased salivary secretion. The sodium-glucose cotransporter 1 (SGLT1) protein, which transports 1 glucose/2 Na+/264 H2O molecules, is described in...

    Authors: Robinson Sabino-Silva, Maristela Mitiko Okamoto, Aline David-Silva, Rosana Cristina Mori, Helayne Soares Freitas and Ubiratan Fabres Machado
    Citation: Diabetology & Metabolic Syndrome 2013 5:64
    Content type: Short report Published on:

  43. Current International Diabetes Federation guidelines recommend a target HbA1c <7.0%, but many people with diabetes worldwide find this difficult to achieve, increasing their risk of developing complications. This...

    Authors: Leon Litwak, Su-Yen Goh, Zanariah Hussein, Rachid Malek, Vinay Prusty and Mohammad E Khamseh
    Citation: Diabetology & Metabolic Syndrome 2013 5:57
    Content type: Research Published on:

  44. The pathogenesis between cerebral vascular disease (CVD) and the endothelial dysfunction (ETD) remains elusive in diabetes. Therefore, we investigated the expression of partial vasoactivators which be closely ...

    Authors: Renshi Xu, Rongwei Yang, Huoyou Hu, Qiujiang Xi, Hui Wan and Yuchen Wu
    Citation: Diabetology & Metabolic Syndrome 2013 5:63
    Content type: Research Published on:

  45. The importance of tight blood glucose control among outpatients with diabetes mellitus is well established, however, the management of diabetes in the hospital setting is generally considered secondary in impo...

    Authors: Edson Duarte Moreira Jr, Patricia Carvalho Balthazar Silveira, Raimundo Celestino Silva Neves, Clodoaldo Souza Jr, Zaira Onofre Nunes and Maria da Conceição C Almeida
    Citation: Diabetology & Metabolic Syndrome 2013 5:62
    Content type: Research Published on:

    The Erratum to this article has been published in Diabetology & Metabolic Syndrome 2013 5:78

  46. Neonatal STZ treatment induces a state of mild hyperglycemia in adult rats that disrupts metabolism and maternal/fetal interactions. The aim of this study was investigate the effect of neonatal STZ treatment o...

    Authors: Ana Carolina Inhasz Kiss, Barbara Woodside, Yuri Karen Sinzato, Maria Martha Bernardi, Wilma De Grava Kempinas, Janete Aparecida Anselmo-Franci and Débora Cristina Damasceno
    Citation: Diabetology & Metabolic Syndrome 2013 5:61
    Content type: Research Published on:

  47. Both physical activity and inflammation are important in the pathophysiology of metabolic syndrome (MetS). Our study aim is to explore their associations in an elderly male (≥ 65 years old) cohort.

    Authors: Chia-Ling Chang, Po-Tseng Lee, Wei-Ting Chang, Chin-Sung Chang, Jyh-Hong Chen, Liang-Miin Tsai, Chih-Hsing Wu and Ping-Yen Liu
    Citation: Diabetology & Metabolic Syndrome 2013 5:60
    Content type: Research Published on:

  48. The prevalence of undiagnosed diabetes mellitus (DM) in Greenland has been reported very high with only 30% of cases diagnosed. In 2010, glycosylated hemoglobin (A1C) was introduced as a diagnostic tool in Gre...

    Authors: Line Damsgaard and Michael Lynge Pedersen
    Citation: Diabetology & Metabolic Syndrome 2013 5:59
    Content type: Research Published on:

  49. Diabetes mellitus (DM) and thyroid dysfunction (TD) are the two most common endocrine disorders in clinical practice. The unrecognized TD may adversely affect the metabolic control and add more risk to an alre...

    Authors: Cátia Cristina Silva Sousa Vergara Palma, Marco Pavesi, Verônica Guedes Nogueira, Eliete Leão Silva Clemente, Maria de Fátima Bevilacqua Motta Pereira Vasconcellos, Luiz Carlos Pereira Júnior, Fernanda Faissol Pacheco, Tássia Gomide Braga, Ludmila de Faria Bello, Juliana Oliveira Soares, Stefanie Cathren Fenizola dos Santos, Vinícius Paes Leme Cavalcante Campos and Marília Brito Gomes
    Citation: Diabetology & Metabolic Syndrome 2013 5:58
    Content type: Research Published on:

  50. Obesity is common in type 2 diabetes (T2DM) and is associated with increased risk of morbidity and all-cause mortality. This analysis describes weight changes associated with insulin detemir initiation in real...

    Authors: Jean-François Yale, Taner Damci, Marcel Kaiser, Eddy Karnieli, Kamlesh Khunti, Andreas Liebl, Florian MM Baeres, Anne Louise Svendsen and Stuart A Ross
    Citation: Diabetology & Metabolic Syndrome 2013 5:56
    Content type: Research Published on:

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Diabetology & Metabolic Syndrome

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