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  1. Content type: Research

    The deep subcutaneous adipose tissue (dSAT) is closely related to the obesity-associated complications similarly to the characteristics of visceral adipose tissue (VAT). However, the association between dSAT a...

    Authors: Se-Hong Kim, Ju-hye Chung, Sang-Wook Song, Won Sang Jung, Yun-Ah Lee and Ha-Na Kim

    Citation: Diabetology & Metabolic Syndrome 2016 8:10

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  2. Content type: Research

    In most individuals, obesity and insulin resistance coexist. However, some individuals have excessive adipose tissue mass but remain insulin sensitive. Moreover, lean individuals can develop acute inflammation...

    Authors: Samuel D. Moscavitch, Hye C. Kang, Rubens A. C. Filho, Evandro T. Mesquita, Hugo C. C. F. Neto and Maria L. G. Rosa

    Citation: Diabetology & Metabolic Syndrome 2016 8:9

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  3. Content type: Research

    The consumption of hyperlipidic and hypercaloric diet is considered a major factor to promote obesity and the consumption of food with antioxidant properties, like Juçara (Euterpe edulis Mart), could be a tool to...

    Authors: L. M. Oyama, F. P. Silva, J. Carnier, D. A. de Miranda, A. B. Santamarina, E. B. Ribeiro, C. M. Oller do Nascimento and V. V. de Rosso

    Citation: Diabetology & Metabolic Syndrome 2016 8:8

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  4. Content type: Review

    The chronic care model (CCM) uses a systematic approach to restructure health care systems. The aim of this systematic review was to examine studies that evaluated different elements of the CCM in patients wi...

    Authors: Deise Regina Baptista, Astrid Wiens, Roberto Pontarolo, Lara Regis, Walleri Christine Torelli Reis and Cassiano Januário Correr

    Citation: Diabetology & Metabolic Syndrome 2016 8:7

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  5. Content type: Research

    Recently, we reported signs of inflammation (raised IL-8, reduced miR-146a) and signs of vascular repair (raised HGF) in the serum of Ecuadorian patients with type 2 diabetes (T2D). In contrast, we found that ...

    Authors: Lucy Baldeón Rojas, Karin Weigelt, Harm de Wit, Behiye Ozcan, Adri van Oudenaren, Fernando Sempértegui, Eric Sijbrands, Laura Grosse, Anton-Jan van Zonneveld, Hemmo A. Drexhage and Pieter J. M. Leenen

    Citation: Diabetology & Metabolic Syndrome 2016 8:6

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  6. Content type: Research

    The vascular effects exerted by GLP-1 are mediated by several synergistic mechanisms such as involvement of nitric oxide and natriuresis. Recently, it was demonstrated that atrial natriuretic peptide (ANP) is ...

    Authors: David Nathanson, Mats Frick, Bengt Ullman and Thomas Nyström

    Citation: Diabetology & Metabolic Syndrome 2016 8:5

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  7. Content type: Research

    Deregulation of glycemic and glycated hemoglobin (HbA1) levels accelerate the progression of cardiovascular complications in type 1 diabetes mellitus (T1DM). The aim of this study was to investigate the associati...

    Authors: Sandra de Oliveira, Dahan da Cunha Nascimento, Ramires Alsamir Tibana, Samuel Lima de Oliveira, Ivo Vieira de Sousa Neto, Roberta Kelly Menezes Maciel Falleiros, Leonardo Garcia Miranda, Hermelinda Cordeiro Pedrosa, James Wilfred Navalta, Guilherme Borges Pereira and Jonato Prestes

    Citation: Diabetology & Metabolic Syndrome 2016 8:4

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  8. Content type: Research

    We carried out a case–control study in patients with type 2 diabetes mellitus (T2DM) to evaluate the association between seven single nucleotide polymorphisms (SNPs) previously described to be linked to diabet...

    Authors: Marjoriê P. Buffon, Mariana P. Carpena, Denise A. Sortica, Andressa Santer, Rodrigo Carlessi, Bianca M. de Souza, Maria I. Edelweiss, Milton Berger, Daisy Crispim and Luís H. Canani

    Citation: Diabetology & Metabolic Syndrome 2016 8:3

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  9. Content type: Review

    Diabetes mellitus (DM) is a public health issue, affecting around 382 million people worldwide. In order to achieve glycemic goals, insulin therapy is the frontline therapy for type 1 DM patients; for patients...

    Authors: Freddy Goldberg Eliaschewitz and Tânia Barreto

    Citation: Diabetology & Metabolic Syndrome 2016 8:2

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  10. Content type: Research

    To compare the effects of nateglinide and rosiglitazone on inflammatory markers, GLP-1 levels and metabolic profile in patients with type 2 diabetes (DM2).

    Authors: Glauce Cordeiro Ulhôa Tostes, Maria Rosário Cunha, Rosa Tsumeshiro Fukui, Márcia Regina Silva Correia, Dalva Marreiro Rocha, Rosa Ferreira dos Santos and Maria Elizabeth Rossi da Silva

    Citation: Diabetology & Metabolic Syndrome 2016 8:1

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  11. Content type: Research

    Myeloperoxidase (MPO) is a lysosomal hemoprotein found in the azurophilic granules in neutrophils. Myeloperoxidase plays an important role in oxygen-dependent killing of bacteria, fungi, virus and malignant ce...

    Authors: Mustafa Unubol, Irfan Yavasoglu, Firuzan Kacar, Engin Guney, Imran Kurt Omurlu, Mevlut Ture, Gurhan Kadikoylu and Zahit Bolaman

    Citation: Diabetology & Metabolic Syndrome 2015 7:119

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  12. Content type: Review

    Diabetic kidney disease (DKD) is a chronic complication of diabetes mellitus, which is considered a worldwide epidemic. Several studies have been developed in order to elucidate possible genetic factors involv...

    Authors: Marjoriê Piuco Buffon, Denise Alves Sortica, Fernando Gerchman, Daisy Crispim and Luís Henrique Canani

    Citation: Diabetology & Metabolic Syndrome 2015 7:118

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  13. Content type: Research

    Progranulin (PGRN) is a cysteine rich secreted protein, expressed in epithelial cells, immune cells, neurons, and adipocytes. It was first identified for its growth factor-like properties, being involved in ea...

    Authors: Bruna Bellincanta Nicoletto and Luis Henrique Canani

    Citation: Diabetology & Metabolic Syndrome 2015 7:117

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  14. Content type: Research

    Diabetic retinopathy is the main cause of preventable blindness in the economically active population in western countries. Diabetic retinopathy screening is effective in preventing blindness and can be perfor...

    Authors: Fernando Korn Malerbi, Paulo Henrique Morales, Michel Eid Farah, Karla Rezende Guerra Drummond, Tessa Cerqueira Lemos Mattos, André Araújo Pinheiro, Felipe Mallmann, Ricardo Vessoni Perez, Franz Schubert Lopes Leal, Marília Brito Gomes and Sergio Atala Dib

    Citation: Diabetology & Metabolic Syndrome 2015 7:116

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  15. Content type: Research

    Hyperglycemia has been associated with decreased blood flow in various organs, leading to tissue damage and dysfunctions. Exercise training (ET) is known to promote beneficial changes in the autonomic nervous ...

    Authors: Sarah Cristina Ferreira Freitas, Ângela d’Avila Harthmann, Bruno Rodrigues, Maria-Cláudia Irigoyen and Kátia De Angelis

    Citation: Diabetology & Metabolic Syndrome 2015 7:115

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  16. Content type: Short report

    Inpatient hyperglycemia is associated with adverse outcomes in hospitalized patients, with or without known diabetes. The adherence to American College of Endocrinology and American Diabetes Association guidel...

    Authors: Marcos Tadashi Kakitani Toyoshima, Alexandre Barbosa Câmara de Souza, Sharon Nina Admoni, Priscilla Cukier, Simão Augusto Lottenberg, Ana Claudia Latronico and Márcia Nery

    Citation: Diabetology & Metabolic Syndrome 2015 7:114

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  17. Content type: Research

    Diabetes and its complications are substantial causes of morbidity and mortality, and caused approximately 5.1 million deaths worldwide in 2013. Early detection and treatment of diabetes complications can prev...

    Authors: Deise Regina Baptista, Rubia Daniela Thieme, Walleri Christini Torelli Reis, Roberto Pontarolo and Cassyano Januário Correr

    Citation: Diabetology & Metabolic Syndrome 2015 7:113

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  18. Content type: Research

    Metabolic syndrome (MetS) contains a cluster of cardiovascular risk factors. People with MetS are more susceptible to cardiovascular disease, diabetes mellitus, and cancer. Endothelin-1 (ET-1) and matrix metal...

    Authors: A. P. Yu, B. T. Tam, W. Y. Yau, K. S. Chan, S. S. Yu, T. L. Chung and P. M. Siu

    Citation: Diabetology & Metabolic Syndrome 2015 7:111

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  19. Content type: Research

    Elevated levels of fibrinogen may contribute to a prothrombotic state. Cross-sectional studies suggest fibrinogen possibly linked with MetS/its components, while results of cohort studies remain controversial....

    Authors: Lijie Ding, Chengqi Zhang, Guang Zhang, Tao Zhang, Min Zhao, Xiaokang Ji, Zhongshang Yuan, Ruihong Liu, Fang Tang and Fuzhong Xue

    Citation: Diabetology & Metabolic Syndrome 2015 7:110

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  20. Content type: Research

    Over recent decades, Brazilian mortality registration has undergone increasing improvement in terms of completeness and quality in cause of death reporting. These improvements, however, complicate the descript...

    Authors: Maria Inês Schmidt, Bruce B. Duncan, Lenice Ishitani, Glaura da Conceição Franco, Daisy Maria Xavier de Abreu, Gustavo C. Lana and Elisabeth França

    Citation: Diabetology & Metabolic Syndrome 2015 7:109

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  21. Content type: Research

    It is well-established that nonalcoholic fatty liver disease (NAFLD) is associated with type 2 diabetes mellitus (T2DM). Complement-C1q TNF-related protein 5 (CTRP5) is a novel adipokine involved in the regula...

    Authors: Solaleh Emamgholipour, Nariman Moradi, Maani Beigy, Parisa Shabani, Reza Fadaei, Hossein Poustchi and Mahmood Doosti

    Citation: Diabetology & Metabolic Syndrome 2015 7:108

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  22. Content type: Research

    Hyperglycemia and insulin resistance often develop cardiovascular and nephrological dysfunction in diabetic patients. Sitagliptin is used to treat diabetes and showed potential benefit in lowering increased bl...

    Authors: Md. Ashraful Alam, Mohammed Riaz Hasan Chowdhury, Preeti Jain, Md. Abu Taher Sagor and Hasan Mahmud Reza

    Citation: Diabetology & Metabolic Syndrome 2015 7:107

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  23. Content type: Research

    Using patient data from the GetGoal-Duo1, -L, and L-Asia trials, the objectives of this study were to evaluate and compare the impact of lixisenatide once-daily add-on treatment to basal insulin therapy ±oral ...

    Authors: Kazuhiro Eto, Yusuke Naito and Yutaka Seino

    Citation: Diabetology & Metabolic Syndrome 2015 7:106

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  24. Content type: Research

    The raising prevalence of weight excess and of non-communicable diseases in indigenous populations, as well as changes in food consumption and reduction in the frequency and intensity of physical activity, sug...

    Authors: Luana Padua Soares, Amaury Lelis Dal Fabbro, Anderson Soares Silva, Daniela Saes Sartorelli, Luciana Ferreira Franco, Patrícia Chamadoira Kuhn, Regina Santiago Moises, João Paulo Botelho Vieira-Filho and Laércio Joel Franco

    Citation: Diabetology & Metabolic Syndrome 2015 7:105

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  25. Content type: Short report

    Insulin resistance with elevated glucose is a risk factor for non-alcoholic steatohepatitis (NASH). We investigated the effects of the sodium glucose cotransporter 2 (SGLT2) inhibitor luseogliflozin on NASH de...

    Authors: Shirong Qiang, Yusuke Nakatsu, Yasuyuki Seno, Midori Fujishiro, Hideyuki Sakoda, Akifumi Kushiyama, Keiichi Mori, Yasuka Matsunaga, Takeshi Yamamotoya, Hideaki Kamata and Tomoichiro Asano

    Citation: Diabetology & Metabolic Syndrome 2015 7:104

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  26. Content type: Research

    Diabetic kidney disease (DKD) is the leading cause of end stage renal disease worldwide and is associated with increased cardiovascular mortality. The endothelin system has been implicated in the pathogenesis ...

    Authors: Claudete M. Zanatta, Daisy Crispim, Denise A. Sortica, Lucas P. Klassmann, Jorge L. Gross, Fernando Gerchman and Luís H. Canani

    Citation: Diabetology & Metabolic Syndrome 2015 7:103

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  27. Content type: Short report

    Permanent neonatal diabetes mellitus (PNDM) is a rare disorder, characterized by uncontrolled hyperglycemia diagnosed during the first 6 months of life. In general, PNDM has a genetic origin and most frequentl...

    Authors: Adriana Mangue Esquiaveto-Aun, Maricilda Palandi De Mello, Maria Fernanda Vanti Macedo Paulino, Walter José Minicucci, Gil Guerra-Júnior and Sofia Helena Valente De Lemos-Marini

    Citation: Diabetology & Metabolic Syndrome 2015 7:101

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  28. Content type: Research

    Insulin resistance is a major component of metabolic syndrome, type 2 Diabetes Mellitus (T2DM) and coronary artery disease (CAD). Although important in T2DM, its role as a predictor of CAD in non-diabetic pati...

    Authors: Márcio Mossmann, Marco V. Wainstein, Sandro C. Gonçalves, Rodrigo V. Wainstein, Gabriela L. Gravina, Marlei Sangalli, Francine Veadrigo, Roselene Matte, Rejane Reich, Fernanda G. Costa and Marcello C. Bertoluci

    Citation: Diabetology & Metabolic Syndrome 2015 7:100

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  29. Content type: Research

    Hyperprolactinemia has been associated with changes in body composition and metabolic abnormalities. Normalization of prolactin (PRL) with dopamine agonists has been found to reverse these abnormalities. This ...

    Authors: Nazir A. Pala, Bashir A. Laway, Raiz A. Misgar and Rayees A. Dar

    Citation: Diabetology & Metabolic Syndrome 2015 7:99

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  30. Content type: Research

    Diabetes mellitus is one of the most important risk factors for atherosclerosis. However, the mechanisms underlying high-glucose-induced atherosclerosis remain unclear. This study was designed to observe the e...

    Authors: Xiao-Yan Zhao, Xiao-Fang Wang, Ling Li, Li Zhang, De-Liang Shen, Dan-Hua Li, Qiang-Song Jin and Jin-Ying Zhang

    Citation: Diabetology & Metabolic Syndrome 2015 7:98

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  31. Content type: Research

    The escalating rate of diabetes’ has prompted researchers around the world to explore for early markers. A deficit of functional β-cell mass plays a central role in the pathophysiology of type 2 diabetes. The REG

    Authors: Sadaf Saleem Uppal, Abdul Khaliq Naveed, Saeeda Baig and Bushra Chaudhry

    Citation: Diabetology & Metabolic Syndrome 2015 7:96

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    The Erratum to this article has been published in Diabetology & Metabolic Syndrome 2016 8:20

  32. Content type: Meeting abstract

    Authors: Guilherme Coutinho Kullmann Duarte, Tais Silveira Assmann, Égina Marina Barbosa Martins, Mariana Lopes dos Santos, Luis Henrique Canani and Daisy Crispim

    Citation: Diabetology & Metabolic Syndrome 2015 7(Suppl 1):A215

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    This article is part of a Supplement: Volume 7 Supplement 1

  33. Content type: Meeting abstract

    Authors: Fabio Vasconcellos Comim, Etiane Tatsch, Bruna Hausen, Juliana Wispel, Leo Canterle Dal Osto, Rizzi Adhan de Viera, Paola Roehrs Colpo, Pietra Zorzo, Lucas Venturini Zottele, Karen Koff da Costa, Rafael Noal Moresco and Melissa Orlandin Premaor

    Citation: Diabetology & Metabolic Syndrome 2015 7(Suppl 1):A144

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    This article is part of a Supplement: Volume 7 Supplement 1

  34. Content type: Meeting abstract

    Authors: Livia Silveira Mastella, Leticia Schwerz Weinert, Vanessa Gnielka, Vânia Naomi Hirakata, Maria Lúcia Rocha Oppermann, Sandra Pinho Silveiro and Angela de Azevedo Jacob Reichelt

    Citation: Diabetology & Metabolic Syndrome 2015 7(Suppl 1):A81

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    This article is part of a Supplement: Volume 7 Supplement 1

  35. Content type: Meeting abstract

    Authors: Thaís Leal Silva, Luana Alves Freitas Afiune, Rafaianne Queiroz de Moraes Souza, Thaigra de Sousa Soares, Thalita Bohnen Carneiro, Madilene Francely Américo, Kleber Eduardo de Campos and Gustavo Tadeu Volpato

    Citation: Diabetology & Metabolic Syndrome 2015 7(Suppl 1):A77

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    This article is part of a Supplement: Volume 7 Supplement 1

  36. Content type: Meeting abstract

    Authors: Ana Paula Bouças Kochenborger, Ana Paula Kutscher Ripoll, Bianca Marmontel de Souza, Pamela Sachs Nique, Denise Alves Sortica, Natali Cardoso, Sandra Pinho Silveiro, Leticia Schwerz Weinert, Sergio Hofmeister de Almeida Martins Costa, Luís Henrique Canani and Daisy Crispim

    Citation: Diabetology & Metabolic Syndrome 2015 7(Suppl 1):A75

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    This article is part of a Supplement: Volume 7 Supplement 1

  37. Content type: Meeting abstract

    Authors: Marcos Oliveira Pires de Almeida, Leyna Leite Santos, Denise Dantas Lima, Taciana Borges Cavalcanti, Amanda Aleixo, Vanessa Silva de Almeida, Diego de Sousa Dantas, Bárbara Bernardo Silva, Evandro Cabral de Brito and Paulo André Freire Magalhães

    Citation: Diabetology & Metabolic Syndrome 2015 7(Suppl 1):A42

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    This article is part of a Supplement: Volume 7 Supplement 1

  38. Content type: Meeting abstract

    Authors: Bárbara Limberger Nedel, Leticia Maria Tedesco Silva, Monique de Moura Machado, Rodrigo Soares de Souza Marques, Leonardo de Andrade Mesquita, Luciana Pavan Antoniolli, Tassia Cividanes Pazinato, Vanessa Piccoli, Mayara Abichequer Beer, Anize Delfino von Frankenberg and Fernando Gerchman

    Citation: Diabetology & Metabolic Syndrome 2015 7(Suppl 1):A38

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    This article is part of a Supplement: Volume 7 Supplement 1

  39. Content type: Meeting abstract

    Authors: Cybelle da Silva Nery, Marcos Paulo Galdino Coutinho, Deniele Bezerra Lós, Kamilla Dinah Santos de Lira, Filipe Barbosa Cunha de Miranda, Ana Carolina Salvador de Lucena, Ana Camila Nobre de Lacerda Brito, Silvia Luana Ramos Marques, Márcio Almeida Bezerra and Sílvia Regina Arruda de Moraes

    Citation: Diabetology & Metabolic Syndrome 2015 7(Suppl 1):A9

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    This article is part of a Supplement: Volume 7 Supplement 1


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