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  1. Whether polymorphisms in tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), interleukin-10 (IL-10) or adiponectin (ADIPOQ) influence the risk of gestational diabetes mellitus (GDM) or not remain inconclusive....

    Authors: Qiqi Huang, Yi Wang, Binbin Gu and Yanwen Xu

    Citation: Diabetology & Metabolic Syndrome 2020 12:81

    Content type: Research

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  2. The disclosure in the media of a benefit with the use of dexamethasone in patients with COVID-19 infection sets precedents for self-medication and inappropriate use of corticosteroids.

    Authors: Janine Alessi, Giovana B. de Oliveira, Beatriz D. Schaan and Gabriela H. Telo

    Citation: Diabetology & Metabolic Syndrome 2020 12:80

    Content type: Review

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  3. Patients with severe mental illness (SMI) are at increased risk of developing non-communicable diseases that could cause significantly lower life expectancy when compared to the general population. This study ...

    Authors: Agete Tadewos Hirigo and Tesfaye Teshome

    Citation: Diabetology & Metabolic Syndrome 2020 12:79

    Content type: Research

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  4. Pioglitazone, as a PPAR gamma agonist, is used for the management of type 2 diabetes mellitus. Nevertheless, evidence showed that the therapeutic modulation of PPAR gamma activity using pioglitazone might be l...

    Authors: Ahmad Gholami, Mohammad Hossein Dabbaghmanesh, Younes Ghasemi, Pedram Talezadeh, Farhad Koohpeyma and Nima Montazeri-Najafabady

    Citation: Diabetology & Metabolic Syndrome 2020 12:78

    Content type: Research

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  5. It has been reported that long non-coding RNAs (lncRNAs) play vital roles in diabetic nephropathy (DN). Our study aims to research the function of lncRNA KCNQ1OT1 in DN cells and the molecular mechanism.

    Authors: Ran Jie, Pengpeng Zhu, Jiao Zhong, Yan Zhang and Hongyan Wu

    Citation: Diabetology & Metabolic Syndrome 2020 12:77

    Content type: Research

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  6. In patients with diabetes, the prevalence of depression and anxiety symptoms is about two to four times greater than in the general population. The association between diabetes and mental health disorders coul...

    Authors: Janine Alessi, Giovana Berger de Oliveira, Debora Wilke Franco, Bibiana Brino do Amaral, Alice Scalzilli Becker, Carolina Padilla Knijnik, Gabriel Luiz Kobe, Taíse Rosa de Carvalho, Guilherme Heiden Telo, Beatriz D. Schaan and Gabriela Heiden Telo

    Citation: Diabetology & Metabolic Syndrome 2020 12:76

    Content type: Research

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  7. The aim of this study is to evaluate the impact of diabetes, hypertension, cardiovascular disease and the use of angiotensin converting enzyme inhibitors/angiotensin II receptor blockers (ACEI/ARB) with severi...

    Authors: Bianca de Almeida-Pititto, Patrícia M. Dualib, Lenita Zajdenverg, Joana Rodrigues Dantas, Filipe Dias de Souza, Melanie Rodacki and Marcello Casaccia Bertoluci

    Citation: Diabetology & Metabolic Syndrome 2020 12:75

    Content type: Research

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  8. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Claudia Jara, Felipe Oyarzun-Ampuero, Flavio Carrión, Esteban González-Echeverría, Claudio Cappelli and Pablo Caviedes

    Citation: Diabetology & Metabolic Syndrome 2020 12:74

    Content type: Correction

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    The original article was published in Diabetology & Metabolic Syndrome 2020 12:66

  9. Patients with type 2 diabetes mellitus (T2DM) are characterized by chronic hyperglycemia as a consequence of decreased insulin sensitivity, which contributes to bone demineralization and could also be related ...

    Authors: J. I. Aguayo-Ruiz, T. A. García-Cobián, S. Pascoe-González, S. Sánchez-Enríquez, I. M. Llamas-Covarrubias, T. García-Iglesias, A. López-Quintero, M. A. Llamas-Covarrubias, J. Trujillo-Quiroz and E. A. Rivera-Leon

    Citation: Diabetology & Metabolic Syndrome 2020 12:73

    Content type: Research

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  10. Undercarboxylated osteocalcin (ucOC) is a secreted protein produced by osteoblasts that regulates insulin secretion and insulin sensitivity in rodents. However, the significance of these effects on glucose met...

    Authors: Shogo Funakoshi, Kumiko Yoshimura, Seiki Hirano, Satoko Ohmi, Eri Amano, Yoshiharu Fukuda, Yoshio Terada and Shimpei Fujimoto

    Citation: Diabetology & Metabolic Syndrome 2020 12:72

    Content type: Short report

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  11. Black individuals have a great risk of developing chronic kidney disease (CKD) that is associated with high morbimortality, so it is important to classify them into the correct renal function group. Some equat...

    Authors: Marcela Haas Pizarro, Deborah Conte Santos, Laura Gomes Nunes Melo, Bianca Senger Vasconcelos Barros, Luiza Harcar Muniz, Luís Cristóvão Porto, Dayse Aparecida Silva, Rachel Bregman and Marilia Brito Gomes

    Citation: Diabetology & Metabolic Syndrome 2020 12:71

    Content type: Research

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  12. Treatment indexes using continuous glucose monitoring (CGM) have become standardized internationally, and the use of ambulatory glucose profile (AGP) is currently recommended. However, the relationship between...

    Authors: Akemi Tokutsu, Yosuke Okada, Keiichi Torimoto and Yoshiya Tanaka

    Citation: Diabetology & Metabolic Syndrome 2020 12:70

    Content type: Research

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  13. The regular intake of fiber generates numerous health benefits. However, the efficacy depends on the duration of consumption and the ingested dose. Studies investigating the optimal dose are of interest to ena...

    Authors: Janina de Sales Guilarducci, Breno Augusto Ribeiro Marcelino, Isaac Filipe Moreira Konig, Tamira Maria Orlando, Mary Suzan Varaschin and Luciano José Pereira

    Citation: Diabetology & Metabolic Syndrome 2020 12:69

    Content type: Research

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  14. High glucose (HG) induced podocytes injury plays an important role in diabetes nephropathy (DN) development. Long noncoding RNA cancer susceptibility candidate 2 (CASC2) was found to be decreased in serum of D...

    Authors: Feng Li, Bo Dai and Xiquan Ni

    Citation: Diabetology & Metabolic Syndrome 2020 12:68

    Content type: Research

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  15. The chronic complications of Type 2 Diabetes (T2D) such as macrovascular disease is amplified with the increase in the number of metabolic syndrome (MetS) risk factors. This research aims to study the relation...

    Authors: Riyadh Saif-Ali, Nor Azmi Kamaruddin, Molham AL-Habori, Sami A. Al-Dubai and Wan Zurinah Wan Ngah

    Citation: Diabetology & Metabolic Syndrome 2020 12:67

    Content type: Research

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  16. In type I diabetes mellitus (T1DM) pancreatic β cells are destroyed. Treatment entails exogenous insulin administration and strict diet control, yet optimal glycemic control is hardly attainable. Islet transpl...

    Authors: Claudia Jara, Felipe Oyarzun-Ampuero, Flavio Carrión, Esteban González-Echeverría, Claudio Cappelli and Pablo Caviedes

    Citation: Diabetology & Metabolic Syndrome 2020 12:66

    Content type: Research

    Published on:

    The Correction to this article has been published in Diabetology & Metabolic Syndrome 2020 12:74

  17. Asprosin, a newly identified adipokine, is pathologically increased in individuals with insulin resistance. However, the available evidence on the association of asprosin and type 2 diabetes mellitus (T2DM) st...

    Authors: Shakiba Naiemian, Mohsen Naeemipour, Mehdi Zarei, Moslem Lari Najafi, Ali Gohari, Mohammad Reza Behroozikhah, Hafez Heydari and Mohammad Miri

    Citation: Diabetology & Metabolic Syndrome 2020 12:65

    Content type: Research

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  18. To assess gender differences in Quality of life (QoL) and in sociodemographic, clinical and psychological factors associated with impaired QoL in adults with long-standing type 1 diabetes mellitus (DM1).

    Authors: Ana María Castellano-Guerrero, Raquel Guerrero, Desireé Ruiz-Aranda, Sofia Perea, Alfonso Pumar, Federico Relimpio, Miguel Angel Mangas, Fernando Losada and Maria Asunción Martínez-Brocca

    Citation: Diabetology & Metabolic Syndrome 2020 12:64

    Content type: Research

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  19. Chronic inflammation is involved in the pathogenesis of several metabolic diseases, such as obesity and type 2 diabetes mellitus (T2DM). With the recent worldwide outbreak of coronavirus disease (SARS-CoV-2), ...

    Authors: Mauricio Krause, Fernando Gerchman and Rogério Friedman

    Citation: Diabetology & Metabolic Syndrome 2020 12:63

    Content type: Commentary

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  20. Poor adherence to the medical regimen is a major clinical problem in the management of patients with diabetes. This study sought to investigate the level of medication adherence to antidiabetic therapy and to ...

    Authors: Gebre Teklemariam Demoz, Shishay Wahdey, Degena Bahrey, Halefom Kahsay, Gebremariam Woldu, Yirga Legesse Niriayo and Andrew Collier

    Citation: Diabetology & Metabolic Syndrome 2020 12:62

    Content type: Research

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  21. Chromogranin B (CgB) plays an important role in the physiological insulin secretion of pancreatic beta cells. Serum CgB levels were investigated in type 1 and type 2 diabetes patients in a cross-sectional study.

    Authors: Zoltan Herold, Magdolna Herold, Klara Rosta, Marton Doleschall and Aniko Somogyi

    Citation: Diabetology & Metabolic Syndrome 2020 12:61

    Content type: Short report

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  22. The prevalence of non-alcoholic fatty liver disease (NAFLD) has been increasing rapidly. It is nowadays recognized as the most frequent liver disease, affecting a quarter of global population and regularly coe...

    Authors: Amélio F. Godoy-Matos, Wellington S. Silva Júnior and Cynthia M. Valerio

    Citation: Diabetology & Metabolic Syndrome 2020 12:60

    Content type: Review

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  23. Crocin as a carotenoid exerts anti-oxidant, anti-inflammatory, anti-cancer, neuroprotective and cardioprotective effects. Besides, the increasing prevalence of diabetes mellitus and its allied complications, a...

    Authors: Vahideh Behrouz, Ali Dastkhosh, Mehdi Hedayati, Meghdad Sedaghat, Maryam Sharafkhah and Golbon Sohrab

    Citation: Diabetology & Metabolic Syndrome 2020 12:59

    Content type: Research

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  24. The present study investigated the relationships between psychological stress indices and oxidative stress marker, also when combined with emergent insulin resistance (IR), in the non-diabetic, middle-aged sub...

    Authors: Miroslaw Janczura, Jerzy Dropinski, Anna Gielicz, Katarzyna Kotula-Horowitz, Teresa Iwaniec, Andrzej Stanisz, Rafal Rosa and Teresa B. Domagala

    Citation: Diabetology & Metabolic Syndrome 2020 12:58

    Content type: Research

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  25. Diabetes mellitus (DM) and cardiovascular disease (CVD) are present in a large number of patients with novel Coronavirus disease 2019 (COVID-19). We aimed to determine the risk and predictors of in-hospital mo...

    Authors: Hadith Rastad, Hossein Karim, Hanieh-Sadat Ejtahed, Ramin Tajbakhsh, Mohammad Noorisepehr, Mehrdad Babaei, Mehdi Azimzadeh, Alireza Soleimani, Seyed Hasan Inanloo, Neda Shafiabadi Hassani, Fariba Rasanezhad, Ehsan Shahrestanaki, Zeinab Khodaparast, Hossein Golami and Mostafa Qorbani

    Citation: Diabetology & Metabolic Syndrome 2020 12:57

    Content type: Research

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  26. The American Diabetes Association proposed two subcategories for type 1 diabetes mellitus: type 1A or immune-mediated diabetes (IDM) and type 1B or idiopathic diabetes. The absence of β-cell autoimmune markers...

    Authors: Diana Catarino, Diana Silva, Joana Guiomar, Cristina Ribeiro, Luísa Ruas, Luís Cardoso and Isabel Paiva

    Citation: Diabetology & Metabolic Syndrome 2020 12:56

    Content type: Research

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  27. Diabetic retinopathy (DR) is a specific neurovascular complication of diabetes mellitus (DM). Clinically, family history is a widely recognized risk factor for DR, assisting diagnosis and risk strata. However,...

    Authors: Jin-Rui Wang, Zhongli Chen, Ke Yang, Hui-Jun Yang, Wen-Yu Tao, Yi-Ping Li, Ze-Jia Jiang, Chao-Fang Bai, Yue-Chuan Yin, Jian-Mei Duan, Yuan-Yuan Zhou, Xin-Qian Geng and Ying Yang

    Citation: Diabetology & Metabolic Syndrome 2020 12:55

    Content type: Research

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  28. Sarcopenia is a progressive condition that is characterized by decreases in skeletal muscle mass and function. Although sarcopenia is associated with lifestyle-related diseases (LSRD), the mechanisms underlyin...

    Authors: Takanobu Takata, Akiko Sakasai-Sakai and Masayoshi Takeuchi

    Citation: Diabetology & Metabolic Syndrome 2020 12:54

    Content type: Research

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  29. It is well established that diminished reproductive health is one of the notable long-term outcomes of type 2 diabetes mellitus (T2DM), especially among males. Due to the global increasing rate of T2DM and inf...

    Authors: Marziyeh Rahimiyan-Heravan, Leila Roshangar, Pouran Karimi, Safa Sefidgari-Abrasi, Mohammad Morshedi, Maryam Saghafi-Asl and Khadijeh Bavafa-Valenlia

    Citation: Diabetology & Metabolic Syndrome 2020 12:53

    Content type: Research

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  30. Diabetes mellitus is a chronic disease characterized by high social, economic and health burden, mostly due to the high incidence and morbidity of diabetes complications. Numerous studies have shown that optim...

    Authors: F. Andreozzi, R. Candido, S. Corrao, R. Fornengo, A. Giancaterini, P. Ponzani, M. C. Ponziani, F. Tuccinardi and D. Mannino

    Citation: Diabetology & Metabolic Syndrome 2020 12:52

    Content type: Review

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  31. Previous literatures have implied that the liver fat deposition plays a crucial role in the development and progression of insulin resistance. In the present study, we aimed to investigate the association of l...

    Authors: Yun-Sheng Wang, Jun Ye, Yong-Hong Cao, Rong Zhang, Xiao-Fang Han, Ling-Ling Zou, Lei Kuang, Ji Zhang, Hu Lian, Jin-Xiang Xia, Qiu Zhang and Wu Dai

    Citation: Diabetology & Metabolic Syndrome 2020 12:51

    Content type: Research

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  33. While sufficient evidence supporting universal screening is not available, it is justifiable to look for specific risk factors for gestational diabetes mellitus (GDM) or hyperglycemia in pregnancy (HIP). The o...

    Authors: Bianca F. Nicolosi, Joice M. Vernini, Roberto A. Costa, Claudia G. Magalhães, Marilza V. C. Rudge, José E. Corrente, Jose G. Cecatti and Iracema M. P. Calderon

    Citation: Diabetology & Metabolic Syndrome 2020 12:49

    Content type: Research

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  34. We reported a relatively high rate of MetS in rural Northeast residents in 2012–2013. Many strategies like health knowledge propagation and lifestyle modification have been taken to help rural residents decrea...

    Authors: Shasha Yu, Xiaofan Guo, GuangXiao Li, Hongmei Yang, Guozhe Sun, Liqiang Zheng and Yingxian Sun

    Citation: Diabetology & Metabolic Syndrome 2020 12:48

    Content type: Research

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  35. Type 2 diabetes (T2D) shows a high mortality rate, dependent on disease duration, comorbidities and glucose control over time. Data on patients with short disease duration are scanty.

    Authors: Edoardo Biancalana, Federico Parolini, Alessandro Mengozzi and Anna Solini

    Citation: Diabetology & Metabolic Syndrome 2020 12:47

    Content type: Research

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  36. Reduced sleep quality is common in advanced age. Poor sleep quality is associated with adverse outcomes, chiefly cardiovascular, in young and middle-aged subjects, possibly because of its association with meta...

    Authors: Alice Laudisio, Silvia Giovannini, Panaiotis Finamore, Luca Navarini, Domenico Paolo Emanuele Margiotta, Federica Vannetti, Claudio Macchi, Daniele Coraci, Isabella Imbimbo, Raffaello Molino-Lova, Claudia Loreti, Raffaele Antonelli Incalzi, Giuseppe Zuccalà and Luca Padua

    Citation: Diabetology & Metabolic Syndrome 2020 12:46

    Content type: Research

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  37. In current management of type 2 diabetes (T2DM), cardiovascular and renal prevention have become important targets to be achieved. In this context, a joint panel of four endocrinology societies from Brazil and...

    Authors: Marcello Casaccia Bertoluci, João Eduardo Nunes Salles, José Silva-Nunes, Hermelinda Cordeiro Pedrosa, Rodrigo Oliveira Moreira, Rui Manuel Calado da Silva Duarte, Davide Mauricio da Costa Carvalho, Fábio Rogério Trujilho, João Filipe Cancela dos Santos Raposo, Erika Bezerra Parente, Fernando Valente, Fábio Ferreira de Moura, Alexandre Hohl, Miguel Melo, Francisco Garcia Pestana Araujo, Rosa Maria Monteiro Castro de Araújo Principe…

    Citation: Diabetology & Metabolic Syndrome 2020 12:45

    Content type: Review

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  38. The role of serum fibroblast growth factor 19 (FGF19) in arteriosclerosis is not well known. In the present study, we aimed to explore whether serum FGF19 levels were related to arteriosclerosis parameters, in...

    Authors: Wang-shu Liu, Meng-jie Tang, Tian-li Xu, Jian-bin Su, Xue-qin Wang, Feng Xu, Dong-mei Zhang, Qing Zhu, Jie Cao and Hong Wang

    Citation: Diabetology & Metabolic Syndrome 2020 12:44

    Content type: Research

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  39. Glycosylphosphatidylinositol-specific phospholipase D (GPLD1) is responsible for cleaving membrane-associated glycosylphosphatidylinositol (GPI) molecules, which is affected by diabetes. We aimed to examine th...

    Authors: Farzad Abdolmaleki and Ali Heidarianpour

    Citation: Diabetology & Metabolic Syndrome 2020 12:43

    Content type: Research

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  40. Neuregulin 4 (Nrg4) is a novel neurotrophic adipokine associated with the development of diabetic peripheral neuropathy (DPN), however, the pathological mechanism remains poorly understood. The purpose of our ...

    Authors: Pijun Yan, Zhihong Zhang, Ying Miao, Yong Xu, Jianhua Zhu and Qin Wan

    Citation: Diabetology & Metabolic Syndrome 2020 12:42

    Content type: Research

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  41. Prediabetes can predispose the individual to type 2 diabetes in the long-term. The present study was conducted to determine the effectiveness of vitamin D and omega-3 co-supplementation on glycemic control and...

    Authors: Masoumeh Rajabi-Naeeni, Mahrokh Dolatian, Mostafa Qorbani and Amir Abbas Vaezi

    Citation: Diabetology & Metabolic Syndrome 2020 12:41

    Content type: Research

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  42. Diabetes mellitus in elderly represents an exceptional subset in the population vulnerable to cardiovascular events. As aging, diabetes mellitus and hypertension share common pathways, an ideal treatment shoul...

    Authors: Shaimaa M. Motawea, Rasha I. Noreldin and Yahya M. Naguib

    Citation: Diabetology & Metabolic Syndrome 2020 12:40

    Content type: Research

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  43. LncRNA HAND2-AS1 has been reported to be a tumor suppressor in several types of malignancy, while its involvement in other human diseases is unclear. Our preliminary RNA-seq analysis revealed the downregulatio...

    Authors: Changqing Dong, Shengmao Liu, Yanling Li and Yingchun Cui

    Citation: Diabetology & Metabolic Syndrome 2020 12:39

    Content type: Research

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  44. Emerging observational studies suggest an association between metabolic syndrome (MetS) and osteoarthritis (OA). This meta-analysis was conducted to examine whether or not there is a bidirectional relationship...

    Authors: Sheng-Yao Liu, Wen-Ting Zhu, Bin-Wei Chen, Yuan-Hong Chen and Guo-Xin Ni

    Citation: Diabetology & Metabolic Syndrome 2020 12:38

    Content type: Review

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  45. Sodium–glucose cotransporter 2 (SGLT2) inhibitors are an antihyperglycemic drug with diuretic action. We recently reported that the SGLT2 inhibitor dapagliflozin ameliorates extracellular volume expansion with...

    Authors: Ken Ohara, Takahiro Masuda, Masato Morinari, Mari Okada, Atsushi Miki, Saki Nakagawa, Takuya Murakami, Kentaro Oka, Maki Asakura, Yasuharu Miyazawa, Akito Maeshima, Tetsu Akimoto, Osamu Saito and Daisuke Nagata

    Citation: Diabetology & Metabolic Syndrome 2020 12:37

    Content type: Research

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  46. Recent studies point toward the possible regulatory roles of two lncRNAs; metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) and taurine upregulated gene 1 (TUG1) in the pathogenesis of obesity-re...

    Authors: Reyhane Ebrahimi, Karamollah Toolabi, Naghmeh Jannat Ali Pour, Samaneh Mohassel Azadi, Alireza Bahiraee, Fahimeh Zamani-Garmsiri and Solaleh Emamgholipour

    Citation: Diabetology & Metabolic Syndrome 2020 12:36

    Content type: Research

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  47. The safety of hypoglycemic drugs should be paid more attention to in elderly patients with type 2 diabetes mellitus due to their concomitant diseases, physiological decline of liver and kidney function and cog...

    Authors: Dong-Ni Yu, Lei Qiu, Shang-Yong Ning and Li-Xin Guo

    Citation: Diabetology & Metabolic Syndrome 2020 12:35

    Content type: Research

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  48. Allograft kidney transplantation has become a treatment of choice for patients with end-stage renal disease (ESRD), and post-transplant diabetes mellitus (PTDM) has been associated with impaired patient and gr...

    Authors: Hsuan Yeh, Chihung Lin, Yan-Rong Li, Chieh-Li Yen, Cheng-Chia Lee, Jung-Sheng Chen, Kuan-Hsing Chen, Ya-Chun Tian, Pi-Hua Liu and Ching-Chung Hsiao

    Citation: Diabetology & Metabolic Syndrome 2020 12:34

    Content type: Research

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  49. Diabetic nephropathy (DN) is a severe complication of diabetes with type 1 and 2. Long non-coding RNAs (lncRNAs) are being found to be involved in the DN pathogenesis. In this study, we aimed to further explor...

    Authors: Wen Zhong, Jiaoe Zeng, Junli Xue, Aimin Du and Yancheng Xu

    Citation: Diabetology & Metabolic Syndrome 2020 12:33

    Content type: Research

    Published on:

  50. It is generally accepted that obesity can lead to metabolic disorders such as NAFLD and insulin resistance. However, the underlying mechanism has been poorly understood. Moreover, there is evidence to support ...

    Authors: Reza Afrisham, Sahar Sadegh-Nejadi, Reza Meshkani, Solaleh Emamgholipour and Maliheh Paknejad

    Citation: Diabetology & Metabolic Syndrome 2020 12:32

    Content type: Research

    Published on:


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