Reaven GM: Role of insulin resistance in human disease. Diabetes. 1988, 37: 1595-1607. 10.2337/diabetes.37.12.1595.
Article
CAS
PubMed
Google Scholar
Mantozoros C, Flier J: Insulin resistance: the clinical spectrum. Adv Endocrinol Metab. 1995, 19: 193-232.
Google Scholar
Lillioja S, Mott D, Spraul M, Ferraro R, Foley JE, Ravussin E, Knowler WC, Bennett PH, Bogardus C: Insulin resistance and insulin secretory dysfunction as precursors for noninsulin dependant diabetes mellitus. N Eng J Med. 1993, 329: 1988-1992. 10.1056/NEJM199312303292703.
Article
CAS
Google Scholar
Elbagir M, Eltom M, Elmehadi M, Kadam IM, Berne C: Population-based study of the prevalence of diabetes mellitus and impaired glucose tolerance in adults among in Northern Sudan. Diabetes Care. 1996, 19: 1126-1128. 10.2337/diacare.19.10.1126.
Article
CAS
PubMed
Google Scholar
Elmehadi M, Abdel Rahman L, Mukhtar S: Patterns of diabetes mellitus in Sudan. Trop Geog Med. 1989, 4: 353-355.
Google Scholar
Friedman JM, Halaas JL: Leptin and the regulation of body weight in mammals. Nature. 1998, 395: 763-770. 10.1038/27376.
Article
CAS
PubMed
Google Scholar
Ahima RS, Flier JS: Adipose tissue as an endocrine organ. Trends Endocrinol Metab. 2000, 11: 327-332. 10.1016/S1043-2760(00)00301-5.
Article
CAS
PubMed
Google Scholar
Hotamisligil GS: The role of TNF-a and TNF receptors in obesity and insulin resistance. J Int Med. 1999, 245: 621-625. 10.1046/j.1365-2796.1999.00490.x.
Article
CAS
Google Scholar
Mohamed Ali V, Pinkney JH, Coppack SW: Adipose tissue as an endocrine and paracrine organ. Int J Obes Relat Metab Disord. 1998, 22: 1145-1158. 10.1038/sj.ijo.0800770.
Article
CAS
PubMed
Google Scholar
Scherer PE, Williams S, Fogliano M, Baldini G, Lodish HF: A novel serum protein similar to C1q, produced exclusively in adipocytes. J Biol Chem. 1995, 270 (45): 26746-26749. 10.1074/jbc.270.45.26746.
Article
CAS
PubMed
Google Scholar
Maeda K, Okubo K, Shimomura I, Funahashi T, Matsuzawa Y, Matsubara K: cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcript 1). Biochem Biophys Res Commun. 1996, 221 (2): 286-289. 10.1006/bbrc.1996.0587.
Article
CAS
PubMed
Google Scholar
Hu E, Liang P, Spiegelman BM: AdipoQ is a novel adipose-specific gene dysregulated in obesity. J Biol Chem. 1996, 271 (18): 10697-10703. 10.1074/jbc.271.18.10697.
Article
CAS
PubMed
Google Scholar
Comuzzie AG, Funahashi T, Sonnenberg G, Martin LJ, Jacob HJ, Black AE, Maas D, Takahashi M, Kihara S, Tanaka S, Matsuzawa Y, Blangero J, Cohen D, Kissebah A: The genetic basis of plasma variation in adiponectin, a global endophenotype for obesity and the metabolic syndrome. J Clin Endocrinol Metab. 2001, 86 (9): 4321-4325. 10.1210/jc.86.9.4321.
Article
CAS
PubMed
Google Scholar
Fasshauer M, Klein J, Neumann S, Eszlinger M, Paschke R: Hormonal regulation of adiponectin gene expression in 3 T3-L1 adipocytes. Biochem Biophys Res Commun. 2002, 290 (3): 1084-1089. 10.1006/bbrc.2001.6307.
Article
CAS
PubMed
Google Scholar
Statnick MA, Beavers LS, Conner LJ, Corominola H, Johnson D, Hammond CD, Rafaeloff-Phail R, Seng T, Suter TM, Sluka JP, Ravussin E, Gadski RA, Caro JF: Decreased expression of apM1 in omental and subcutaneous adipose tissue of humans with type 2 diabetes. Int J Exp Diabetes Res. 2000, 1 (2): 81-88. 10.1155/EDR.2000.81.
Article
PubMed Central
CAS
PubMed
Google Scholar
Halleux CM, Takahashi M, Delporte ML, Detry R, Funahashi T, Matsuzawa Y, Brichard SM: Secretion of adiponectin and regulation of apM1 gene expression in human visceral adipose tissue. Biochem Biophys Res Commun. 2001, 288 (5): 1102-1107. 10.1006/bbrc.2001.5904.
Article
CAS
PubMed
Google Scholar
Weyer C, Funahashi T, Tanaka S, Hotta K, Matsuzawa Y, Pratley RE, Tataranni PA: Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. J Clin Endocrinol Metab. 2001, 86 (5): 1930-1935. 10.1210/jc.86.5.1930.
Article
CAS
PubMed
Google Scholar
Hotta K, Funahashi T, Arita Y, Takahashi M, Matsuda M, Okamoto Y, Iwahashi H, Kuriyama H, Ouchi N, Maeda K, Nishida M, Kihara S, Sakai N, Nakajima T, Hasegawa K, Muraguchi M, Ohmoto Y, Nakamura T, Yamashita S, Hanafusa T, Matsuzawa Y: Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler Thromb Vasc Biol. 2000, 20 (6): 1595-1599. 10.1161/01.ATV.20.6.1595.
Article
CAS
PubMed
Google Scholar
Arita Y, Kihara S, Ouchi N, Takahashi M, Maeda K, Miyagawa J, Hotta K, Shimomura I, Nakamura T, Miyaoka K, Kuriyama H, Nishida M, Yamashita S, Okubo K, Matsubara K, Muraguchi M, Ohmoto Y, Funahashi T, Matsuzawa Y: Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun. 1999, 257 (1): 79-83. 10.1006/bbrc.1999.0255.
Article
CAS
PubMed
Google Scholar
Cnop M, Havel PJ, Utzschneider KM, Carr DB, Sinha MK, Boyko EJ, Retzlaff BM, Knopp RH, Brunzell JD, Kahn SE: Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: evidence for independent roles of age and sex. Diabetologia. 2003, 46 (4): 459-469.
CAS
PubMed
Google Scholar
Yamamoto Y, Hirose H, Saito I, Tomita M, Taniyama M, Matsubara K, Okazaki Y, Ishii T, Nishikai K, Saruta T: Correlation of the adipocyte-derived protein adiponectin with insulin resistance index and serum high-density lipoprotein-cholesterol, independent of body mass index, in the Japanese population. Clin Sci (Lond). 2002, 103 (2): 137-142. 10.1042/CS20010336.
Article
CAS
Google Scholar
Matsubara M, Maruoka S, Katayose S: Inverse relationship between plasma adiponectin and leptin concentrations in normal-weight and obese women. Eur J Endocrinol. 2002, 147 (2): 173-180. 10.1530/eje.0.1470173.
Article
CAS
PubMed
Google Scholar
Stefan N, Vozarova B, Funahashi T, Matsuzawa Y, Weyer C, Lindsay RS, Youngren JF, Havel PJ, Pratley RE, Bogardus C, Tataranni PA: Plasma adiponectin concentration is associated with skeletal muscle insulin receptor tyrosine phosphorylation, and low plasma concentration precedes a decrease in whole-body insulin sensitivity in humans. Diabetes. 2002, 51 (6): 1884-1888. 10.2337/diabetes.51.6.1884.
Article
CAS
PubMed
Google Scholar
Yamauchi T, Kamon J, Waki H, Terauchi Y, Kubota N, Hara K, Mori Y, Ide T, Murakami K, Tsuboyama-Kasaoka N, Ezaki O, Akanuma Y, Gavrilova O, Vinson C, Reitman ML, Kagechika H, Shudo K, Yoda M, Nakano Y, Tobe K, Nagai R, Kimura S, Tomita M, Froguel P, Kadowaki T: The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med. 2001, 7 (8): 941-946. 10.1038/90984.
Article
CAS
PubMed
Google Scholar
Kubota N, Terauchi Y, Yamauchi T, Kubota T, Moroi M, Matsui J, Eto K, Yamashita T, Kamon J, Satoh H, Yano W, Froguel P, Nagai R, Kimura S, Kadowaki T, Noda T: Disruption of adiponectin causes insulin resistance and neointimal formation. J Biol Chem. 2002, 277 (29): 25863-25866. 10.1074/jbc.C200251200.
Article
CAS
PubMed
Google Scholar
Yokota T, Oritani K, Takahashi I, Ishikawa J, Matsuyama A, Ouchi N, Kihara S, Funahashi T, Tenner AJ, Tomiyama Y, Matsuzawa Y: Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages. Blood. 2000, 96 (5): 1723-1732.
CAS
PubMed
Google Scholar
Ouchi N, Kihara S, Arita Y, Okamoto Y, Maeda K, Kuriyama H, Hotta K, Nishida M, Takahashi M, Muraguchi M, Ohmoto Y, Nakamura T, Yamashita S, Funahashi T, Matsuzawa Y: Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway. Circulation. 2000, 102 (11): 1296-1301. 10.1161/01.CIR.102.11.1296.
Article
CAS
PubMed
Google Scholar
Ouchi N, Kihara S, Arita Y, Nishida M, Matsuyama A, Okamoto Y, Ishigami M, Kuriyama H, Kishida K, Nishizawa H, Hotta K, Muraguchi M, Ohmoto Y, Yamashita S, Funahashi T, Matsuzawa Y: Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages. Circulation. 2001, 103 (8): 1057-1063. 10.1161/01.CIR.103.8.1057.
Article
CAS
PubMed
Google Scholar
Hulver MW, Saleh O, MacDonald KG, Pories WJ, Barakat HA: Ethnic differences in adiponectin levels. Metabolism. 2004, 53 (1): 1-3. 10.1016/j.metabol.2003.07.002.
Article
CAS
PubMed
Google Scholar
Osei K, Gaillard T, Kaplow J, Bullock M, Schuster D: Effects of rosglitazone on plasma adiponectin, insulin sensitivity, and insulin secretion in high-risk African Americans with impaired glucose tolerance test and type 2 diabetes. Metabolism. 2004, 53 (12): 1552-1557. 10.1016/j.metabol.2004.06.023.
Article
CAS
PubMed
Google Scholar
Koebnick C, Roberts CK, Shaibi GQ, Kelly LA, Lane CJ, Toledo-Corral CM, Davis JN, Ventura EE, Alexander K, Weigensberg MJ, Goran MI: Adiponectin and leptin are independently associated with insulin sensitivity, but not with insulin secretion or beta-cell function in overweight Hispanic adolescents. Horm Metab Res. 2008, 40 (10): 708-712. 10.1055/s-2008-1077097.
Article
CAS
PubMed
Google Scholar
Mente A, Razak F, Blankenberg S, Vuksan V, Davis AD, Miller R, Teo K, Gerstein H, Sharma AM, Yusuf S, Anand SS, Study of the Health Assessment And Risk Evaluation; Study of the Health Assessment And Risk Evaluation in Aboriginal Peoples Investigators: Ethnic variation in adiponectin and leptin levels and their association with adiposity and insulin resistance. Diabetes Care. 2010, 33 (7): 1629-1634. 10.2337/dc09-1392.
Article
PubMed Central
CAS
PubMed
Google Scholar
Khoo CM, Sairazi S, Taslim S, Gardner D, Wu Y, Lee J, Van Dam RM, Shyong TE: Ethnicity modifies the relationships of insulin resistance, inflammation, and adiponectin with obesity in a multiethnic Asian population. Diabetes Care. 2011, 34 (5): 1120-1126. 10.2337/dc10-2097.
Article
PubMed Central
PubMed
Google Scholar
Pereira RI, Wang CC, Hosokawa P, Dickinson LM, Chonchol M, Krantz MJ, Steiner JF, Bessesen DH, Havranek EP, Long CS: Circulating adiponectin levels are lower in Latino versus non-Latino white patients at risk for cardiovascular disease, independent of adiposity measures. BMC Endocr Disord. 2011, 11: 13-10.1186/1472-6823-11-13.
Article
PubMed Central
CAS
PubMed
Google Scholar
Matthews D, Hosker J, Rudenski A, Naylor BA, Treacher DF, Turner RC: Homeostasis model assessment: insulin resistance and B-cell function from fasting glucose and insulin concentrations in man. Diabetologia. 1985, 28: 412-419. 10.1007/BF00280883.
Article
CAS
PubMed
Google Scholar
Ferris WF, Naran NH, Crowther NJ, Rheeder P, van der Merwe L, Chetty N: The relationship between insulin sensitivity and serum adiponectin levels in three population groups. Horm Metab Res. 2005, 37 (11): 695-701. 10.1055/s-2005-870580.
Article
CAS
PubMed
Google Scholar
Tschritter O, Fritsche A, Thamer C, Haap M, Shirkavand F, Rahe S, Staiger H, Maerker E, Haring H, Stumvoll M: Plasma adiponectin concentrations predict insulin sensitivity of both glucose and lipid metabolism. Diabetes. 2003, 52 (2): 239-243.
Article
CAS
PubMed
Google Scholar
Gil-Campos M, Canete RR, Gil A: Adiponectin, the missing link in insulin resistance and obesity. Clin Nutr. 2004, 23 (5): 963-974. 10.1016/j.clnu.2004.04.010.
Article
CAS
PubMed
Google Scholar
Bergman RN, Mittelman SD: Central role of the adipocyte in insulin resistance. J Basic Clin Physiol Pharmacol. 1998, 9: 205-221.
Article
CAS
PubMed
Google Scholar
Putz DM, Goldner WS, Bar RS, Haynes WG, Sivitz WI: Adiponectin and C-reactive protein in obesity, type 2 diabetes, and monodrug therapy. Metabolism. 2004, 53 (11): 1454-1461. 10.1016/j.metabol.2004.06.013.
Article
CAS
PubMed
Google Scholar
Gavrila A, Chan JA, Yiannakouris N, Kontogiani M, Miller LC, Orlova C, Mantozoros CS: Serum adiponectin levels are inversely associated with overall and central fat distribution but are not directly regulated by acute fasting or leptin administration in humans: Cross-sectional and interventional studies. J Clin Endocrinol Metab. 2003, 88 (10): 4823-4831. 10.1210/jc.2003-030214.
Article
CAS
PubMed
Google Scholar
Choi KM, Lee J, Lee KW, Seo JA, Oh JH, Kim SG, Kim NH, Choi DS, Baik SH: The associations between plasma adiponectin, ghrelin levels and cardiovascular risk factors. Eur J Endocrinol. 2004, 150 (5): 715-718. 10.1530/eje.0.1500715.
Article
CAS
PubMed
Google Scholar
Holdstock C, Engstrom BE, Ohrvall M, Lind L, Sundbom M, Karlsson FA: Effect of bariatric surgery on adipose tissue regulatory peptides and growth hormone secretion. Asia Pac J Clin Nutr. 2004, 13: S41-
Google Scholar