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  1. Content type: Research

    Increased carotid intima-media thickness (CIMT), a marker of subclinical atherosclerosis, is an independent predictor of future cardiovascular events, and has been reported in children with various chronic dis...

    Authors: Maria Fernanda Gontijo Sepulveda Fusaro, Jovita Lane Soares Santos Zanini and Ivani Novato Silva

    Citation: Diabetology & Metabolic Syndrome 2016 8:74

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  2. Content type: Research

    To evaluate the role of adipose tissue function on the association of fatty liver (FL) with impaired fasting glucose (IFG) or newly diagnosed type 2 diabetes mellitus (nT2D).

    Authors: Esteban Jorge-Galarza, Aida Medina-Urrutia, Rosalinda Posadas-Sánchez, Carlos Posadas-Romero, Guillermo Cardoso-Saldaña, Gilberto Vargas-Alarcón, Nacú Caracas-Portilla, Carmen González-Salazar, Margarita Torres-Tamayo and Juan Gabriel Juárez-Rojas

    Citation: Diabetology & Metabolic Syndrome 2016 8:73

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  4. Content type: Review

    The prevalence of diabetes has increased since the last decade in New Brunswick. Identifying factors contributing to the increase in diabetes prevalence will help inform an action plan to manage the condition....

    Authors: Véronique Thibault, Mathieu Bélanger, Emilie LeBlanc, Lise Babin, Stuart Halpine, Beverly Greene and Michelina Mancuso

    Citation: Diabetology & Metabolic Syndrome 2016 8:71

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  5. Content type: Research

    Diabetes is increasing globally, particularly in low and middle income countries, posing a great challenge to health systems. Brazil is currently ranked 4th in the world in terms of the absolute number of pers...

    Authors: Betine Pinto Moehlecke Iser, Álvaro Vigo, Bruce Bartholow Duncan and Maria Inês Schmidt

    Citation: Diabetology & Metabolic Syndrome 2016 8:70

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  6. Content type: Research

    This post hoc analysis examined the efficacy and safety of twice-daily insulin lispro low mixture (LM25) and once-daily basal insulin glargine plus once-daily prandial insulin lispro (IGL) in a Latin American ...

    Authors: Arturo Rojas, Georgina Sposetti, Jorge L. Gross, Douglas Eugenio Barbieri, Ran Duan, Bruno Linetzky, Janaina Martins De Lana, Oded Stempa and Angel Rodriguez

    Citation: Diabetology & Metabolic Syndrome 2016 8:69

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  7. Content type: Research

    Maternal obesity is associated with several adverse pregnancy outcomes. This study was conducted aiming to evaluate maternal levels of adipokines and insulin in pregnancies complicated by overweight and obesit...

    Authors: Joice Monaliza Vernini, Jusciéle Brogin Moreli, Roberto Antônio Araújo Costa, Carlos Antonio Negrato, Marilza Vieira Cunha Rudge and Iracema Mattos Paranhos Calderon

    Citation: Diabetology & Metabolic Syndrome 2016 8:68

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  8. Content type: Research

    Diabetes is a socioeconomic burden in Pakistan. International diabetes federation reported 6.9 million cases of diabetes and 87,548 deaths due to diabetes in Pakistan in 2014. Peroxisome proliferators-activate...

    Authors: Huma Butt, Shabana and Shahida Hasnain

    Citation: Diabetology & Metabolic Syndrome 2016 8:67

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  9. Content type: Research

    Diabetes mellitus (DM) is considered a global epidemic, and patient self-management education and support are critical in preventing and reducing the risk of complications. Self-monitoring of blood glucose (SM...

    Authors: Miguel Nasser Hissa

    Citation: Diabetology & Metabolic Syndrome 2016 8:66

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  10. Content type: Review

    Diabetes is one of the most important epidemic diseases of this century and the number of people with diabetes has more than doubled over the past three decades. Our aim was to estimate the prevalence of diabe...

    Authors: Gabriela H. Telo, Felipe Vogt Cureau, Martina S. de Souza, Thais S. Andrade, Fabiana Copês and Beatriz D. Schaan

    Citation: Diabetology & Metabolic Syndrome 2016 8:65

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  11. Content type: Research

    We investigated the effect of longitudinal status change in metabolic syndrome (MetS) assessed by two different criteria on new onset of type 2 diabetes (NODM) in a Japanese population.

    Authors: Hirofumi Ohnishi, Shigeyuki Saitoh, Hiroshi Akasaka, Tetsuaki Furukawa, Mitsuru Mori and Tetsuji Miura

    Citation: Diabetology & Metabolic Syndrome 2016 8:64

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  13. Content type: Research

    To examine the correlation between the fasting plasma glucose and HbA1c levels using regression equation and to assess the average fasting plasma glucose levels for the specific HbA1c (A1C) goals in the patien...

    Authors: Sangmo Hong, Jun Goo Kang, Chul Sik Kim, Seong Jin Lee, Chang Beom Lee and Sung-Hee Ihm

    Citation: Diabetology & Metabolic Syndrome 2016 8:62

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  14. Content type: Research

    Gestational diabetes mellitus (GDM) is a risk factor for the development of diabetes mellitus (DM). However, there is a low return rate for this screening, so it is important to search for earlier methods for ...

    Authors: Aline Nabuco, Samara Pimentel, Carolina A. Cabizuca, Melanie Rodacki, Denise Finamore, Marcus M. Oliveira and Lenita Zajdenverg

    Citation: Diabetology & Metabolic Syndrome 2016 8:61

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  15. Content type: Research

    Obesity is known to promote mild hyperthyrotropinaemia by unknown metabolic mechanisms. This investigation aimed to explore the association between thyroid function and metabolic phenotype in euthyroid obese i...

    Authors: Paolo Marzullo, Chiara Mele, Stefania Mai, Gabriele Guzzaloni, Davide Soranna, Maria Antonella Tagliaferri, Maria Elisa Berselli, Flavia Prodam, Daniela Surico, Gianluca Aimaretti and Massimo Scacchi

    Citation: Diabetology & Metabolic Syndrome 2016 8:59

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  16. Content type: Research

    The metabolic syndrome (MS) has been assessed since childhood mainly because of the nutritional and epidemiological transition that has occurred worldwide. Our objectives were to explore the MS and its compone...

    Authors: Ana Elisa Madalena Rinaldi, Gleice Fernanda Costa Pinto Gabriel, Fernando Moreto, José Eduardo Corrente, Kátia Cristina Portero McLellan and Roberto Carlos Burini

    Citation: Diabetology & Metabolic Syndrome 2016 8:58

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  17. Content type: Research

    Gestational diabetes mellitus (GDM) affects approximately 7–17 % of all pregnancies and has been recognized as a significant risk factor to neonatal and maternal health. Postpartum, GDM significantly increases...

    Authors: Lauren A. Kenna, John A. Olsen, Michael G. Spelios, Michael S. Radin and Eitan M. Akirav

    Citation: Diabetology & Metabolic Syndrome 2016 8:60

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  18. Content type: Research

    The treatment and prevention of the metabolic syndrome (MetS) is currently one of the major challenges in medicine. The impact of working conditions on metabolic risk has not been adequately studied. Our objec...

    Authors: Markus Strauß, Peter Foshag, Bianca Przybylek, Marc Horlitz, Alejandro Lucia, Fabian Sanchis-Gomar and Roman Leischik

    Citation: Diabetology & Metabolic Syndrome 2016 8:57

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  19. Content type: Research

    Studies show that educational interventions improve glycemic control in patients with diabetes mellitus (DM), reducing the occurrence of complications associated with the disease.

    Authors: Wilson Eik Filho, Letícia Pastorelli Bonjorno, Ana Julia Mendes Franco, Márcia Lorena Alves dos Santos, Eniuce Menezes de Souza and Sonia Silva Marcon

    Citation: Diabetology & Metabolic Syndrome 2016 8:56

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  20. Content type: Research

    The TOMM20 gene was previously identified as differentially expressed and methylated between severely obese subjects with and without metabolic syndrome (MS). Since metabolic complications do not affect all obese...

    Authors: Juan de Toro-Martín, Frédéric Guénard, André Tchernof, Yves Deshaies, Louis Pérusse, Frédéric-Simon Hould, Stéfane Lebel, Picard Marceau and Marie-Claude Vohl

    Citation: Diabetology & Metabolic Syndrome 2016 8:55

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  21. Content type: Research

    In practice, there is increasing recognition of the importance of hypothalamic pituitary adrenal axis in the cardiovascular disease progression. The association of brain natriuretic peptide with obesity and ch...

    Authors: Mona Schaalan, Waleed Mohamed and Rania Rahmo

    Citation: Diabetology & Metabolic Syndrome 2016 8:52

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  22. Content type: Review

    This review aims at summarizing the present knowledge on the clinical consequences of concomitant coeliac disease (CD) in adult patients with type 1 diabetes mellitus (T1DM). The cause of the increased prevale...

    Authors: Sjoerd F. Bakker, Maarten E. Tushuizen, Boudewina M. E. von Blomberg, Hetty J. Bontkes, Chris J. Mulder and Suat Simsek

    Citation: Diabetology & Metabolic Syndrome 2016 8:51

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  23. Content type: Research

    We aimed to examine the relationship between the occurrence of hypo-/hyperglycemia and HbA1c values, as assessed by continuous glucose monitoring (CGM) in patients with type 1 diabetes.

    Authors: Daisuke Tsujino, Rimei Nishimura, Yoshiko Onda, Chiaki Seo, Kiyotaka Ando, Aya Morimoto and Kazunori Utsunomiya

    Citation: Diabetology & Metabolic Syndrome 2016 8:53

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  24. Content type: Research

    Adherence to treatment has been defined as the degree to which a patient’s behavior corresponds to medical or health advice; however, the most appropriate method to evaluate adherence to diabetes care has yet ...

    Authors: Gabriela Heiden Telo, Martina Schaan de Souza, Thais Stürmer Andrade and Beatriz D’Agord Schaan

    Citation: Diabetology & Metabolic Syndrome 2016 8:54

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  25. Content type: Review

    Type 2 diabetes mellitus (DM) globally affects 18–20 % of adults over the age of 65 years. Diabetic kidney disease (DKD) is one of the most frequent and dangerous complications of DM2, affecting about one-thir...

    Authors: Roberto Pecoits-Filho, Hugo Abensur, Carolina C. R. Betônico, Alisson Diego Machado, Erika B. Parente, Márcia Queiroz, João Eduardo Nunes Salles, Silvia Titan and Sergio Vencio

    Citation: Diabetology & Metabolic Syndrome 2016 8:50

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  26. Content type: Research

    The aim of this study was to determine the impact of metabolic syndrome (MetS) on lipid target achievements in the Arabian Gulf.

    Authors: Ibrahim Al-Zakwani, Wael Al Mahmeed, Abdullah Shehab, Mohamed Arafah, Ali T. Al-Hinai, Omer Al Tamimi, Mahmoud Al Awadhi, Shorook Al Herz, Faisal Al Anazi, Khalid Al Nemer, Othman Metwally, Akram Alkhadra, Mohammed Fakhry, Hossam Elghetany, Abdel Razak Medani, Afzal Hussein Yusufali…

    Citation: Diabetology & Metabolic Syndrome 2016 8:49

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  27. Content type: Research

    This study aims to assess serum vaspin in early stages of glucose intolerance and in the presence of metabolic syndrome (MetS); and to evaluate vaspin correlation to different cardio-metabolic parameters and a...

    Authors: Rumyana Dimova, Tsvetalina Tankova, Georgi Kirilov, Nevena Chakarova, Lilia Dakovska and Greta Grozeva

    Citation: Diabetology & Metabolic Syndrome 2016 8:46

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  28. Content type: Research

    Sex hormone binding globulin (SHBG), a glycoprotein produced by hepatocytes that transports testosterone and other steroids in plasma, is a marker for developing metabolic syndrome and T2DM. SHBG is present in...

    Authors: Swapna Dharashivkar, Lawrence Wasser, Richard N. Baumgartner, Jeffrey C. King and Stephen J. Winters

    Citation: Diabetology & Metabolic Syndrome 2016 8:47

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  29. Content type: Research

    Sodium-glucose co-transporter-2 (SGLT2) inhibitors are new oral antidiabetic drugs that reduce hyperglycemia by promoting urinary glucose excretion. Glycosuria produced by SGLT2 inhibitors is associated with w...

    Authors: Teruo Jojima, Takanori Tomotsune, Toshie Iijima, Kazumi Akimoto, Kunihiro Suzuki and Yoshimasa Aso

    Citation: Diabetology & Metabolic Syndrome 2016 8:45

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  30. Content type: Research

    Women with gestational diabetes mellitus (GDM) are required to control their blood glucose shortly after GDM diagnosis to minimize adverse pregnancy outcomes. A real time-continuous glucose monitoring system (...

    Authors: Eman Alfadhli, Eman Osman and Taghreed Basri

    Citation: Diabetology & Metabolic Syndrome 2016 8:48

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  31. Content type: Research

    Poor glycemic control in patients with type 2 diabetes is commonly recorded worldwide; Latin America (LA) is not an exception. Barriers to intensifying insulin therapy and which barriers are most likely to neg...

    Authors: Bruno Linetzky, Brad Curtis, Gustavo Frechtel, Renan Montenegro Jr., Miguel Escalante Pulido, Oded Stempa, Janaina Martins de Lana and Juan José Gagliardino

    Citation: Diabetology & Metabolic Syndrome 2016 8:41

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  32. Content type: Research

    Gestational diabetes mellitus (GDM) increases the risk for preeclampsia and macrosomia. GDM is conventionally diagnosed by an oral glucose tolerance test (OGTT). Hemoglobin A1c (HbA1c) is a marker for the aver...

    Authors: Ingrid Hov Odsæter, Arne Åsberg, Eszter Vanky, Siv Mørkved, Signe Nilssen Stafne, Kjell Åsmund Salvesen and Sven Magnus Carlsen

    Citation: Diabetology & Metabolic Syndrome 2016 8:43

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  33. Content type: Research

    The aim of this study was to investigate the association and interaction of metabolic syndrome (MetS) and estrogen receptor alpha 1 (ESR1) gene polymorphisms on cardiovascular autonomic neuropathy (CAN).

    Authors: Fangfang Zeng, Linuo Zhou and Zihui Tang

    Citation: Diabetology & Metabolic Syndrome 2016 8:42

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  35. Content type: Review

    The association of anthropometric (waist circumference) and hemodynamic (blood pressure) changes with abnormalities in glucose and lipid metabolism has been motivation for a lot of discussions in the last 30 y...

    Authors: Heno F. Lopes, Maria Lúcia Corrêa-Giannella, Fernanda M. Consolim-Colombo and Brent M. Egan

    Citation: Diabetology & Metabolic Syndrome 2016 8:40

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  36. Content type: Research

    Describe the overweight frequency (overweight and obesity) and identify the factors associated with this in children and adolescents with type 1 diabetes mellitus (T1DM) treated at a University Children’s Hosp...

    Authors: Verônica Medeiros da Costa, Patricia de Carvalho Padilha, Géssica Castor Fontes de Lima, Aline Alves Ferreira, Jorge Luiz Luescher, Luciana Porto and Wilza Arantes Ferreira Peres

    Citation: Diabetology & Metabolic Syndrome 2016 8:39

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  37. Content type: Research

    Type 2 diabetes (T2D) and colon cancer (CC) are numbered among the most common diseases in the world. The decreased activity of natural killer (NK) cells previously revealed in both mentioned pathological sta...

    Authors: Paweł Piątkiewicz, Małgorzata Bernat-Karpińska, Tomasz Miłek, Michał Rabijewski and Elżbieta Rosiak

    Citation: Diabetology & Metabolic Syndrome 2016 8:38

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  38. Content type: Research

    To determine whether US and European participants in the Liraglutide Effect and Action in Diabetes: Evaluation of cardiovascular outcome Results (LEADER) trial differ regarding risk factors for cardiovascular ...

    Authors: Guy E. H. M. Rutten, Cees J. Tack, Thomas R. Pieber, Abdurrahman Comlekci, David Dynnes Ørsted, Florian M. M. Baeres, Steven P. Marso and John B. Buse

    Citation: Diabetology & Metabolic Syndrome 2016 8:37

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  39. Content type: Research

    The GetGoal-L-Asia and -S trials were multi-center trials conducted in 4 and 16 countries, respectively including Japan that evaluated the efficacy and safety of lixisenatide add-on treatment vs. placebo among...

    Authors: Hiroaki Seino, Yukiko Onishi, Yusuke Naito and Mitsuhisa Komatsu

    Citation: Diabetology & Metabolic Syndrome 2016 8:36

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  40. Content type: Research

    In 2011, private pharmacies associated to the Brazilian Ministry of Health provided patients with two types of insulin (regular human insulin and isophane insulin or NPH) and three oral antidiabetic medication...

    Authors: João Leopoldo Oliveira Araujo, Mariana Donato Pereira, Cristiane de Cássia Bergamaschi, Fernando de Sá Del Fiol, Luciane Cruz Lopes, Maria Inês de Toledo and Silvio Barberato-Filho

    Citation: Diabetology & Metabolic Syndrome 2016 8:35

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  41. Content type: Research

    Helicobacter pylori (H. pylori) infection is reported to be associated with various extragastrointestinal conditions such as insulin resistance, diabetes mellitus and metabolic syndrom...

    Authors: Wesam Ahmed Nasif, Mohammed Hasan Mukhtar, Mohammed Mahmoud Nour Eldein and Sami Sadagah Ashgar

    Citation: Diabetology & Metabolic Syndrome 2016 8:34

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  42. Content type: Short report

    A rare sign of some malignant tumors is a sudden eruption of multiple seborrheic keratoses called Leser-Trélat sign. Overproduction of insulin-like growth factor-2 (IGF2) or its precursor is the main mechanism...

    Authors: Andreia Latanza Gomes Mathez, Debora Moroto, Sergio Atala Dib and Joao Roberto de Sa

    Citation: Diabetology & Metabolic Syndrome 2016 8:33

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  43. Content type: Research

    Dietary factors are important environmental factors associated with the prevalence of metabolic syndrome (MS). The objective of this study was to assess the habitual nutrient intakes of patients with MS.

    Authors: Aline Tuane Oliveira da Cunha, Hermilla Torres Pereira, Sephora Louyse Silva de Aquino, Cristiane Hermes Sales, Karine Cavalcanti Maurício Sena-Evangelista, Josivan Gomes Lima, Severina Carla Vieira Cunha Lima and Lucia Fatima Campos Pedrosa

    Citation: Diabetology & Metabolic Syndrome 2016 8:32

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  44. Content type: Research

    Distal symmetric polyneuropathy (DSPN) is the most common complication of type 2 diabetes mellitus (T2DM) and the most common form of peripheral neuropathy. DSPN increases the risk of foot ulceration up to sev...

    Authors: Bogdan Timar, Simona Popescu, Romulus Timar, Flavia Baderca, Bogdan Duica, Mihaela Vlad, Codrina Levai, Bogdan Balinisteanu and Mihaela Simu

    Citation: Diabetology & Metabolic Syndrome 2016 8:31

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  45. Content type: Research

    Few studies have assessed the association between health literacy (HL) and healthy lifestyle characteristics among Japanese people, and reports on the association between HL and prevalence of metabolic syndrom...

    Authors: Hirohide Yokokawa, Hiroshi Fukuda, Motoyuki Yuasa, Hironobu Sanada, Teruhiko Hisaoka and Toshio Naito

    Citation: Diabetology & Metabolic Syndrome 2016 8:30

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  46. Content type: Research

    Metabolic syndrome (MetS) is a cluster of risk factors for type 2 diabetes (Type2 DM) and cardiovascular diseases (CVD), and its prevalence varies based on region, population, and sex. Newborns of women with M...

    Authors: Hamilton dos Prazeres Tavares, Débora Cristina Damasceno Meirelles dos Santos, Joelcio Francisco Abbade, Carlos Antonio Negrato, Paulo Adão de Campos, Iracema Mattos Paranhos Calderon and Marilza Vieira Cunha Rudge

    Citation: Diabetology & Metabolic Syndrome 2016 8:27

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  47. Content type: Research

    Double diabetes (DD) describes both individuals with obesity upon diagnosis of type 1 diabetes and those who have gained weight during follow-up, although cardiovascular risk factors (CVRF) are not well unders...

    Authors: Fernando M. A. Giuffrida, Caroline Bulcão, Roberta A. Cobas, Carlos Antonio Negrato, Marilia B. Gomes and Sergio Atala Dib

    Citation: Diabetology & Metabolic Syndrome 2016 8:28

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  48. Content type: Research

    Polymorphisms of vitamin D receptor (VDR) gene have been studied as genetic markers of type 1 diabetes mellitus (T1DM) and some studies have reported associations with autoimmune thyroid disease. The aim of th...

    Authors: Denise Barreto Mory, Monica Andrade Lima Gabbay, Eloá R. Rocco, Teresa Kasamatsu, Felipe Crispim, Walquíria Lopes Miranda and Sérgio Atala Dib

    Citation: Diabetology & Metabolic Syndrome 2016 8:29

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  49. Content type: Research

    This uncontrolled open label study evaluated the effect of dipeptidyl peptidase-4 inhibitors (DPP-4i): sitagliptin and vildagliptin on augmentation index standardized for 75 beats per minute (cAiX@75), blood p...

    Authors: Lea Duvnjak and Kristina Blaslov

    Citation: Diabetology & Metabolic Syndrome 2016 8:26

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  50. Content type: Research

    Studies on diabetic foot and its complications involving a significant and representative sample of patients in South American countries are scarce. The main objective of this study was to acquire clinical and...

    Authors: Maria Candida R. Parisi, Arnaldo Moura Neto, Fabio H. Menezes, Marilia Brito Gomes, Rodrigo Martins Teixeira, José Egídio Paulo de Oliveira, Joana Rodrigues Dantas Pereira, Reine Marie Chaves Fonseca, Lorena Barreto Arruda Guedes, Adriana Costa e Forti, Ana Mayra Andrade de Oliveira, Marta Barreto de Medeiros Nóbrega, Víctor Nóbrega Quintas Colares, Helena Schmid, Otto Henrique Nienov, Marcia Nery…

    Citation: Diabetology & Metabolic Syndrome 2016 8:25

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