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  1. This study intends to explore whether, or to what extent, the estimated remnant-like particle cholesterol was associated with coronary collateralization in patients with chronic total occlusion lesions.

    Authors: Ang Gao, Jinxing Liu, Yan Liu, Chengping Hu, Yong Zhu, Yujie Zhou, Hongya Han and Yingxin Zhao
    Citation: Diabetology & Metabolic Syndrome 2022 14:57
    Content type: Research Published on:

  2. Phosphodiesterase type 5 inhibitors restore nitric oxide signaling, that plays a significant role in erectile function, and appears to counteract insulin resistance in animal and human models. This study was a...

    Authors: Min-Kyung Lee, Jae-Hyuk Lee, Seo-Young Sohn, Seo Yeon Lee, Tae-Yoong Jeong and Sae Chul Kim
    Citation: Diabetology & Metabolic Syndrome 2022 14:56
    Content type: Research Published on:

  3. Body mass index was intimately associated with islet function, which was affected by various confounding factors. Among all methods of statistical analysis, Mendelian randomization best ruled out bias to find ...

    Authors: Xuekui Liu, Huihui Xu, Ying Liu, Manqing Yang, Wei Xu, Houfa Geng and Jun Liang
    Citation: Diabetology & Metabolic Syndrome 2022 14:55
    Content type: Research Published on:

  4. Diabetes mellitus increases the risk of developing hypertension. The relationship between glycosylated hemoglobin A1c (HbA1c) level and incident hypertension remains controversial. This study examined the asso...

    Authors: Lijuan Liu, Donghu Zhen, Songbo Fu, Weiming Sun, Hongli Li, Nan Zhao, Lijie Hou and Xulei Tang
    Citation: Diabetology & Metabolic Syndrome 2022 14:54
    Content type: Research Published on:

  5. Non-alcoholic fatty liver disease (NAFLD) is considered to be one of the most common chronic liver diseases across worldwide. Epigallocatechin-3-gallate (EGCG) derived from extract of green tea and is well kno...

    Authors: Yuanyuan Zhang, Ruili Yin, Jianan Lang, Ying Fu, Longyan Yang and Dong Zhao
    Citation: Diabetology & Metabolic Syndrome 2022 14:53
    Content type: Research Published on:

  6. Patients with type-2 diabetes mellitus (T2DM), have a higher risk of future cardiovascular diseases (CVD). Meanwhile, probiotics are shown to positively impact CVD-related parameters. This randomized controlle...

    Authors: Fatemeh Ahmadian, Elham Razmpoosh, Hanieh-Sadat Ejtahed, Maryam Javadi, Parvin Mirmiran and Fereidoun Azizi
    Citation: Diabetology & Metabolic Syndrome 2022 14:52
    Content type: Research Published on:

  8. There is still controversy regarding the associations of urinary albumin excretion (UAE) and estimated glomerular filtration rate (eGFR) with atherosclerosis in patients with type 2 diabetes mellitus (T2DM). T...

    Authors: Jun-Wei Wang, Jiang-Feng Ke, Zhi-Hui Zhang, Jun-Xi Lu and Lian-Xi Li
    Citation: Diabetology & Metabolic Syndrome 2022 14:50
    Content type: Research Published on:

  9. In order to evaluate right ventricular (RV) systolic and diastolic dysfunctions in patients with type 2 diabetes mellitus (T2DM) with poor glycemic control by layer specific global longitudinal strain (GLS) an...

    Authors: Jun Huang, Li Li, Li Fan and Dong-liang Chen
    Citation: Diabetology & Metabolic Syndrome 2022 14:49
    Content type: Research Published on:

  10. Digital therapeutics are defined as therapeutic interventions that are driven by high quality software programs to prevent, manage or treat a medical disorder. These products provide great potential to improve...

    Authors: Marcela Rassi-Cruz, Fernando Valente and Maria Vanina Caniza
    Citation: Diabetology & Metabolic Syndrome 2022 14:48
    Content type: Commentary Published on:

  12. Type 1 Diabetes Mellitus (T1DM) impacts health-related quality of life (HRQoL). Cross-sectional studies suggest that low levels of vitamin D (VD) may impair HRQoL, however, the effect of VD supplementation on ...

    Authors: Ana Carolina Contente Braga de Souza, Maria Clara Neres Iunes de Oliveira, Gabriela Nascimento de Lemos, Emanuele Rocha da Silva, Ícaro José Araújo de Souza, Wanderson Maia da Silva, Angélica Leite de Alcântara, Nivin Mazen Said, Lorena Vilhena de Moraes, João Felício Abrahão Neto, Simone Rodrigues dos Passos, Ádria Aline Alves Monteiro, Natércia Neves Marques de Queiroz, Franciane Trindade Cunha de Melo, Karem Miléo Felício, Lilian de Souza D’Albuquerque Silva…
    Citation: Diabetology & Metabolic Syndrome 2022 14:46
    Content type: Research Published on:

  13. Nonalcoholic fatty liver disease (NAFLD) can develop in lean individuals. Despite a better metabolic profile, the risk of disease progression to hepatic inflammation, fibrosis, and decompensated cirrhosis in t...

    Authors: Johanna K. DiStefano and Glenn S. Gerhard
    Citation: Diabetology & Metabolic Syndrome 2022 14:45
    Content type: Review Published on:

  15. Glucose-6-phosphate dehydrogenase (G6PD) deficiency is one of the most common human genetic abnormalities, with a high prevalence in Guangdong, China. The purpose of this study was to explore the characteristi...

    Authors: Aijing Xu, Minyan Jiang, Wen Zhang, Yunting Lin, Yongxian Shao, Huifen Mei, Jing Cheng, Cuili Liang, Cuiling Li, Xiuzhen Li and Li Liu
    Citation: Diabetology & Metabolic Syndrome 2022 14:43
    Content type: Research Published on:

  16. Metabolic syndrome is characterized by several conditions including abdominal obesity, dyslipidemia, impaired glucose levels, and hypertension; which all are directly associated with an increased risk of cardi...

    Authors: Ali Jamshidi, Mojtaba Farjam, Maryam Ekramzadeh and Reza Homayounfar
    Citation: Diabetology & Metabolic Syndrome 2022 14:42
    Content type: Research Published on:

  17. At present, an increasing number of studies are trying to determine whether dapagliflozin has a significant effect on the occurrence and development of atherosclerosis in patients with type 2 diabetes mellitus...

    Authors: Qian-Long Wu, Ting Zheng, Sheng-Zhen Li, Jin-An Chen, Zi-Chun Xie, Jian-Mei Lai, Ji-Yuan Zeng, Jin-Ting Lin, Jia-Shuan Huang and Min-Hua Lin
    Citation: Diabetology & Metabolic Syndrome 2022 14:41
    Content type: Review Published on:

  18. This study aimed to analyze the extent and direction of disagreement between self- and proxy-reported quality of life (QoL) and the factors associated with QoL overestimation and underestimation by caregivers ...

    Authors: Anna Stahl-Pehe, Silvia Selinski, Christina Bächle, Katty Castillo, Karin Lange, Reinhard W. Holl and Joachim Rosenbauer
    Citation: Diabetology & Metabolic Syndrome 2022 14:40
    Content type: Research Published on:

  21. The COVID-19 pandemic led to an unprecedented crisis, and early on, it has been shown that diabetes is an important risk factor for complications and mortality in infected patients, as demonstrated by several ...

    Authors: Thiago Bosco Mendes, Alexandre Barbosa Câmara-de-Souza and Bruno Halpern
    Citation: Diabetology & Metabolic Syndrome 2022 14:37
    Content type: Review Published on:

  22. We previously reported that (neo)adjuvant chemotherapy adversely altered metabolic syndrome (MetS) components, body composition, and related biomarkers after a 12 to 18-week chemotherapy treatment course in wo...

    Authors: Christina M. Dieli-Conwright, Louise Wong, Sarah Waliany and Joanne E. Mortimer
    Citation: Diabetology & Metabolic Syndrome 2022 14:36
    Content type: Research Published on:

  25. Long non-coding RNAs (lncRNAs) have been shown to be involved in the regulation of many disease progression. However, the role of lncRNA HOX transcript antisense RNA (HOTAIR) in diabetic nephropathy (DN) remai...

    Authors: Xin Wang, Wei Wang, Weizhong HuangFu, Zhonghua Liu and Feng Zhao
    Citation: Diabetology & Metabolic Syndrome 2022 14:33
    Content type: Research Published on:

  26. Oral semaglutide is a novel glucagon-like peptide-1 (GLP-1) analog that has been associated with improvements in glycated hemoglobin (HbA1c) and body weight versus sodium-glucose cotransporter-2 inhibitor empa...

    Authors: Samuel J. P. Malkin, Davide Carvalho, Catarina Costa, Vasco Conde and Barnaby Hunt
    Citation: Diabetology & Metabolic Syndrome 2022 14:32
    Content type: Research Published on:

  27. Diabetes mellitus (DM) is known to be a risk factor for dementia. However, it is unclear if hypoglycemic events play a role in the risk of dementia. We aimed to systematically review evidence on the risk of de...

    Authors: Lifen Huang, Manlian Zhu and Jie Ji
    Citation: Diabetology & Metabolic Syndrome 2022 14:31
    Content type: Review Published on:

  28. Dipeptidyl peptidase-4 inhibitors (DPP-4i) decrease glucose levels by regulating incretin peptides in type 2 diabetes mellitus (T2DM). This study aimed to determine the modulatory effect of DPP-4i on brain nat...

    Authors: Liying Mu, Zhuo Wang, Jinmei Ren, Xiaowei Xiong, Zening Jin and Xin Liu
    Citation: Diabetology & Metabolic Syndrome 2022 14:30
    Content type: Research Published on:

  29. Epidemiological studies investigating the association between dietary fructose intake and the metabolic syndrome (MetS) are scarce and have produced controversial findings. This study aimed at (1) assessing to...

    Authors: Rita Aoun, Fatima Al Zahraa Chokor, Mandy Taktouk, Mona Nasrallah, Hussain Ismaeel, Hani Tamim and Lara Nasreddine
    Citation: Diabetology & Metabolic Syndrome 2022 14:29
    Content type: Research Published on:

  30. Diabetic nephropathy (DN) is the leading cause of the end-stage renal disease (ESRD). The proliferation and apoptosis of mesangial cells induced by the activated Wnt/β-catenin pathway is crucial in DN. Trigone...

    Authors: Chen Chen, Yan Shi, Jiulong Ma, Zhen Chen, Ming Zhang and Yan Zhao
    Citation: Diabetology & Metabolic Syndrome 2022 14:28
    Content type: Research Published on:

  31. Adropin, a newly‑identified energy homeostasis protein, has been implicated in the maintenance of metabolic homeostasis and insulin sensitivity. This study attempts to measure the association between serum adr...

    Authors: Wen Wei, Hui Liu, Xiuping Qiu, Jushun Zhang, Jianqing Huang, Hangju Chen, Shuilin Qiu, Ruiyu Lin, Shihai Li and Mei Tu
    Citation: Diabetology & Metabolic Syndrome 2022 14:27
    Content type: Research Published on:

  32. Toll-like receptors (TLRs) are critical sensors for the conservation of bacterial molecules and play a key role in host defense against pathogens. The effect of TLRs on the maintenance of diabetic nephropathy ...

    Authors: Jinfeng Shen, Zaiyou Dai, Yunsheng Li, Huiping Zhu and Lijin Zhao
    Citation: Diabetology & Metabolic Syndrome 2022 14:26
    Content type: Research Published on:

  33. Variants in the Hepatocyte Nuclear Factor 1 Alpha gene (HNF1A) are associated with lipoproteins levels and type 2 diabetes. In this study, we aimed to assess the association of HNF1A gene and haplotypes with the ...

    Authors: Hamza Dallali, Meriem Hechmi, Imane Morjane, Sahar Elouej, Haifa Jmel, Yosra Ben Halima, Abdelmajid Abid, Afef Bahlous, Abdelhamid Barakat, Henda Jamoussi, Sonia Abdelhak and Rym Kefi
    Citation: Diabetology & Metabolic Syndrome 2022 14:25
    Content type: Research Published on:

  34. Plasma 1,5-anhydro-d-glucitol (1,5-AG) may be a easily accessible marker for glycemic variability under mild-to-moderate hyperglycemia. The present study was to investigate the association of 1,5-AG with peripher...

    Authors: Feng Xu, Li-hua Zhao, Xiao-hua Wang, Chun-hua Wang, Chao Yu, Xiu-lin Zhang, Li-yan Ning, Hai-yan Huang, Jian-bin Su and Xue-qin Wang
    Citation: Diabetology & Metabolic Syndrome 2022 14:24
    Content type: Research Published on:

  35. The comparatively low 25 hydroxyvitamin D [25(OH)D] levels have been reported in patients with metabolic syndrome (MetS). Herein we investigated the cross-sectional and longitudinal relationships between serum...

    Authors: Hanyuan Xu, Guiyan Han, Linjie Wang, Huihua Ding, Chunyan Wang, Xiaochuan Ping, Caixia Dong, Dianxi Zhang, Yufei Dai, Naishi Li, Yufeng Li, Hongbo Yang, Huijuan Zhu, Hui Pan, Fengying Gong, Jichun Chen…
    Citation: Diabetology & Metabolic Syndrome 2022 14:23
    Content type: Research Published on:

  36. Diabetes is one of the major public health concerns. Prediabetes can increase the risk of developing some non-communicable diseases such as type 2 diabetes. Given the increasing trend of prediabetes, it is cri...

    Authors: Majid Karandish, Hassan Mozaffari-khosravi, Seyed Mohammad Mohammadi, Bahman Cheraghian and Maryam Azhdari
    Citation: Diabetology & Metabolic Syndrome 2022 14:22
    Content type: Research Published on:

  37. Diabetic nephropathy (DN) is a critical and the most common microvascular complication and its pathogenesis is still faintly understood. Thus, this study was performed to examine the long non-coding RNA ZNFX1 ...

    Authors: Zhuang Geng, Bingzi Dong, Wenshan Lv, Zhongchao Wang, Xiang Wang, YaJing Huang, Yangang Wang and Lili Xu
    Citation: Diabetology & Metabolic Syndrome 2022 14:21
    Content type: Research Published on:

  38. As a result of the continuous rise in the incidence of type 2 diabetes mellitus (T2DM), related cardiovascular diseases (CVDs) have been a main healthy burden worldwide. This study aimed to investigate the pot...

    Authors: Yongdi Wang and Jian Wang
    Citation: Diabetology & Metabolic Syndrome 2022 14:20
    Content type: Research Published on:

  39. This study aimed to assess whether a higher insulin response increased the long-term risk of mortality in a non-diabetic population.

    Authors: Xiaoxia Shen, Siyao He, Jinping Wang, Xin Qian, Hui Wang, Bo Zhang, Yanyan Chen, Hui Li and Guangwei Li
    Citation: Diabetology & Metabolic Syndrome 2022 14:19
    Content type: Research Published on:

  40. Association of single nucleotide polymorphisms (SNP) rs7756992 A/G and rs7754840 G/C of cyclin-dependent kinase 5 regulatory subunit-associated protein 1-like 1 (CDKAL1) gene with the susceptibility of gestationa...

    Authors: U. S. Mahzabin Amin, Nahid Parvez, Tahia Anan Rahman, Md. Rakibul Hasan, Keshob Chandra Das, Sharmin Jahan, Muhammad Abul Hasanat, Zeba I. Seraj and Md. Salimullah
    Citation: Diabetology & Metabolic Syndrome 2022 14:18
    Content type: Research Published on:

  41. The purpose of this study was to assess subclinical left ventricle (LV) myocardial dysfunction using global myocardial work (MW) in type 2 diabetes mellitus (T2DM) patients with preserved left ventricle ejecti...

    Authors: Tao Wang, Li Li, Jun Huang and Li Fan
    Citation: Diabetology & Metabolic Syndrome 2022 14:17
    Content type: Research Published on:

  42. In this study, it was aimed to determine the prevalence and clinical features of obesity and metabolic syndrome, which are long-term effects of survivors after treatment in children with leukemia and lymphoma.

    Authors: İbrahim Kartal, Abdurrahman Alaçam, Ayhan Dağdemir, Cengiz Kara, Oğuz Salih Dinçer, Canan Albayrak and Murat Elli
    Citation: Diabetology & Metabolic Syndrome 2022 14:16
    Content type: Research Published on:

  43. To evaluate the influence of genetic variants and clinical characteristics on the risk of gestational diabetes mellitus (GDM) and to construct and verify a prediction model of GDM in early pregnancy.

    Authors: Qi Wu, Yanmin Chen, Menglin Zhou, Mengting Liu, Lixia Zhang, Zhaoxia Liang and Danqing Chen
    Citation: Diabetology & Metabolic Syndrome 2022 14:15
    Content type: Research Published on:

  44. Diabetic retinopathy (DR) is a serious complication of diabetes. Numerous reports have validated that circular RNAs (circRNAs) participate in DR progression. This study aimed to elucidate the role and potentia...

    Authors: Ting Wang, Chaopeng Li, Min Shi, Shi Zhou, Jiajing Chen and Fang Wang
    Citation: Diabetology & Metabolic Syndrome 2022 14:14
    Content type: Research Published on:

  45. Research suggests that diabetic peripheral neuropathy (DPN) is related to plasma fibrinogen (Fib) concentrations, although its correlation with Fib function has not been reported. Here, the k value and angle α...

    Authors: Yong Zhuang, Xiahong Lin, Xiaoyu Chen, Xiaohong Wu and Jinying Zhang
    Citation: Diabetology & Metabolic Syndrome 2022 14:13
    Content type: Research Published on:

  46. The relation between cigarette smoking and metabolic syndrome (MetS) remains unclear, and previous studies focusing on MetS are limited in sample size. We investigated the association between life-course smoki...

    Authors: Jingya Wang, Yang Bai, Zihang Zeng, Jun Wang, Ping Wang, Yongai Zhao, Weili Xu, Yun Zhu and Xiuying Qi
    Citation: Diabetology & Metabolic Syndrome 2022 14:11
    Content type: Research Published on:

  47. AK098656 may be an adverse factor for coronary heart disease (CHD), especially in patients with hypertension. This study aimed to analyze the effect of AK098656 on CHD and CHD with various complications.

    Authors: Xin Wang, Ya-li Wu, Yuan-yuan Zhang, Jing Ke, Zong-wei Wang, Bao-yu Zhang, Yan Ma, Long-yan Yang and Dong Zhao
    Citation: Diabetology & Metabolic Syndrome 2022 14:10
    Content type: Research Published on:

  48. Although metabolic syndrome traits are risk factors for chronic kidney disease, few studies have examined their association with urinary biomarkers.

    Authors: Keiko Kabasawa, Michihiro Hosojima, Yumi Ito, Kazuo Matsushima, Junta Tanaka, Masanori Hara, Kazutoshi Nakamura, Ichiei Narita and Akihiko Saito
    Citation: Diabetology & Metabolic Syndrome 2022 14:9
    Content type: Research Published on:

  49. Body composition alterations may participate in the pathophysiological processes of type 2 diabetes (T2D). A sedentary lifestyle may be responsible for alterations of body composition and adverse consequences,...

    Authors: Dan-dan Li, Yang Yang, Zi-yi Gao, Li-hua Zhao, Xue Yang, Feng Xu, Chao Yu, Xiu-lin Zhang, Xue-qin Wang, Li-hua Wang and Jian-bin Su
    Citation: Diabetology & Metabolic Syndrome 2022 14:8
    Content type: Research Published on:

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