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  1. The Editors of Diabetology & Metabolic Syndrome would like to thank all of our reviewers, both external and Editorial Board Members, who have contributed to the journal in Volume 6 (2014) and whose valuable suppo...

    Authors: Daniel Giannella-Neto
    Citation: Diabetology & Metabolic Syndrome 2015 7:10
    Content type: Reviewer acknowledgement Published on:

  2. To study the clinical and molecular characteristics of a sample of Brazilian patients with Congenital Hyperinsulinemic Hypoglycemia (CHH).

    Authors: Raphael Del Roio Liberatore Jr, Priscila Manzini Ramos, Gil Guerra Jr, Thais Della Manna, Ivani Novato Silva and Carlos Eduardo Martinelli Jr
    Citation: Diabetology & Metabolic Syndrome 2015 7:5
    Content type: Research Published on:

  3. Prospective studies have shown incidence rates of hypertension in diabetes mellitus to be three times that of subjects without diabetes mellitus. The reverse also applies, with the incidence of diabetes two to...

    Authors: Luciana Sayuri Sanada, Marcelo Rodrigo Tavares, Karina Laurenti Sato, Renata da Silva Ferreira, Milena Cardoso Maia Neubern, Jaci Ayrton Castania, Helio Cesar Salgado and Valéria Paula Sassoli Fazan
    Citation: Diabetology & Metabolic Syndrome 2015 7:9
    Content type: Research Published on:

  4. Low-dose aspirin is recommended to reduce the risk of cardiovascular disease. However, the questions with regard to primary prevention have been raised among patients with diabetes. We evaluated low-dose aspir...

    Authors: Ye-Jee Kim, Nam-Kyong Choi, Mi-Sook Kim, Joongyub Lee, Yoosoo Chang, Jong-Mi Seong, Sun-Young Jung, Ju-Young Shin, Ji-Eun Park and Byung-Joo Park
    Citation: Diabetology & Metabolic Syndrome 2015 7:8
    Content type: Research Published on:

  6. The metabolic syndrome (MS) is characterized by several cardiovascular risk factors and is associated with an increased incidence of diabetes, cardiovascular events and mortality. The prevalence of MS is incre...

    Authors: Fernanda de Carvalho Vidigal, Andréia Queiroz Ribeiro, Nancy Babio, Jordi Salas-Salvadó and Josefina Bressan
    Citation: Diabetology & Metabolic Syndrome 2015 7:6
    Content type: Research Published on:

  7. Metabolic syndrome (MetS) is associated with increased risks of diabetes and atherosclerotic cardiovascular disease. Whether central obesity (CeO) is a prerequisite for the diagnosis of MetS in the Internation...

    Authors: Ki-Bum Won, Hyuk-Jae Chang, Hiroyuki Niinuma, Koichiro Niwa, Kyewon Jeon, In-Jeong Cho, Chi-Young Shim, Geu-Ru Hong and Namsik Chung
    Citation: Diabetology & Metabolic Syndrome 2015 7:3
    Content type: Research Published on:

  8. Bilirubin can prevent lipid oxidation in vitro, but the association in vivo with oxidized low-density lipoprotein (Ox-LDL) levels has been poorly explored. Our aim is to the association of Ox-LDL with total bilir...

    Authors: Henrique Nascimento, Ana Inês Alves, Susana Coimbra, Cristina Catarino, Diana Gomes, Elsa Bronze-da-Rocha, Elísio Costa, Petronila Rocha-Pereira, Luísa Aires, Jorge Mota, Helena Ferreira Mansilha, Carla Rêgo, Alice Santos-Silva and Luís Belo
    Citation: Diabetology & Metabolic Syndrome 2015 7:4
    Content type: Research Published on:

  9. Self-monitoring of blood glucose (SMBG) has been recommended as a useful tool for improving glycemic control, but is still an underutilized strategy and most diabetic patients are not aware of the actions that...

    Authors: Daniel Dutra Romualdo Silva and Adriana Aparecida Bosco
    Citation: Diabetology & Metabolic Syndrome 2015 7:2
    Content type: Research Published on:

  10. Pregnant women with mild gestational hyperglycemia present high risk for hypertension, obesity and hyperglycemia, and appeared to reproduce the model of metabolic syndrome in pregnancy, with hyperinsulinemia a...

    Authors: Rafael Bottaro Gelaleti, Débora Cristina Damasceno, Paula Helena Ortiz Lima, Daisy Maria Favero Salvadori, Iracema de Mattos Paranhos Calderon, José Carlos Peraçoli and Marilza Vieira Cunha Rudge
    Citation: Diabetology & Metabolic Syndrome 2015 7:1
    Content type: Research Published on:

  11. Visceral adiposity contributes to cardiometabolic risk, and visceral adiposity index (VAI) had significant correlation with visceral adiposity. We aimed to explore whether VAI was associated with cardiac struc...

    Authors: Lu Han, Kai-li Fu, Jing Zhao, Zhi-hao Wang, Meng-xiong Tang, Jia Wang, Hui Wang, Yun Zhang, Wei Zhang and Ming Zhong
    Citation: Diabetology & Metabolic Syndrome 2014 6:143
    Content type: Research Published on:

  13. The purpose of this study was to carry out a cross-cultural adaptation to Brazilian Portuguese, validation, and comparison of two questionnaires to measure adherence in patients with type 1 diabetes. There are...

    Authors: Gabriela Heiden Teló, Martina Schaan de Souza and Beatriz D’Agord Schaan
    Citation: Diabetology & Metabolic Syndrome 2014 6:141
    Content type: Research Published on:

  14. Metabolic syndrome (MetS) is a clustering of five metabolic risk factors including abdominal obesity, elevated blood pressure, hypertriglyceridemia, low high-density lipoprotein cholesterol (HDL-C), and impair...

    Authors: Rumana J Khan, Samson Y Gebreab, Pia Riestra, Ruihua Xu and Sharon K Davis
    Citation: Diabetology & Metabolic Syndrome 2014 6:140
    Content type: Research Published on:

  15. Diabetic peripheral neuropathy (DPN) is one of the most common microvascular complications of diabetes. Glycemic variability could be an independent risk factor for diabetes complications in addition to averag...

    Authors: Feng Xu, Li-hua Zhao, Jian-bin Su, Tong Chen, Xue-qin Wang, Jin-feng Chen, Gang Wu, Yan Jin and Xiao-hua Wang
    Citation: Diabetology & Metabolic Syndrome 2014 6:139
    Content type: Research Published on:

  16. Type 2 diabetes mellitus has well known deleterious effects on coronary artery disease (CAD). The role of milder hyperglycemic states such as prediabetes (PD) on CAD is debatable. Glycated hemoglobin (HbA1c) h...

    Authors: Valdecira M Piveta, Celia S Bittencourt, Carolina SV Oliveira, Pedro Saddi-Rosa, Deyse M Meira, Fernando MA Giuffrida and André F Reis
    Citation: Diabetology & Metabolic Syndrome 2014 6:138
    Content type: Research Published on:

  17. The purpose of this research was to study the gene expression of interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), nuclear factor kappa B (NF-κB), vascular endothelial growth factor A (VEGF-A) and adipone...

    Authors: Larisa Litvinova, Dmitriy Atochin, Mariia Vasilenko, Nikolai Fattakhov, Pavel Zatolokin, Igor Vaysbeyn and Elena Kirienkova
    Citation: Diabetology & Metabolic Syndrome 2014 6:137
    Content type: Research Published on:

  18. Cardioprotective effects of Mediterranean-style diet have been shown. Instead of excluding foods, replacement or addition may facilitate compliance with impact on glucose metabolism of individuals at cardiomet...

    Authors: Camila Risso de Barros, Adriana Cezaretto, Maíra Ladeia Rodrigues Curti, Milena Monfort Pires, Luciana Dias Folchetti, Antonela Siqueira-Catania and Sandra Roberta Gouvea Ferreira
    Citation: Diabetology & Metabolic Syndrome 2014 6:136
    Content type: Research Published on:

  19. Ottawa Charter defined health as a resource for everyday life and as an important dimension of health related quality of life (HRqol). Diabetes and obesity have repeatedly been shown as diseases that diminish ...

    Authors: Concepción Vidal-Peracho, Maria Orosia Lucha-López, Ana Carmen Lucha-López, José Miguel Tricás-Moreno, Elena Estébanez-De Miguel and Luis Bernués-Vázquez
    Citation: Diabetology & Metabolic Syndrome 2014 6:135
    Content type: Research Published on:

  20. Coronary artery disease (CAD) is a major cardiovascular complication in diabetic patients. Despite the significant association between obesity and diabetes, the majority of the diabetic subjects are not obese ...

    Authors: Ki-Bum Won, Hyuk-Jae Chang, Hiroyuki Niinuma, Jimin Sung, In-Jeong Cho, Chi-Young Shim, Geu-Ru Hong, Young Jin Kim, Byung-Wook Choi and Namsik Chung
    Citation: Diabetology & Metabolic Syndrome 2014 6:134
    Content type: Research Published on:

  21. Irisin is a novel myokine secreted in response to peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) activation through exercise. The first-degree relatives (FDRs) of type 2 diabetes mellitus...

    Authors: Meili Yang, Peihong Chen, Hua Jin, Xinmiao Xie, Ting Gao, Lili Yang and Xuemei Yu
    Citation: Diabetology & Metabolic Syndrome 2014 6:133
    Content type: Research Published on:

  22. Adipocyte-derived factors and regulators likely contribute to the metabolic syndrome (MetS) in patients with central obesity. This study was undertaken to assess the contribution of leptin, adiponectin, and ac...

    Authors: Heno F Lopes, Richard L Klein, W Timothy Garvey, Theodore Goodfriend and Brent M Egan
    Citation: Diabetology & Metabolic Syndrome 2014 6:132
    Content type: Research Published on:

  23. To assess the presence of insulin resistance (IR) in patients with type 1 diabetes (T1DM) according to the estimated glucose disposal rate formula (eGDR) and the insulin sensitivity score (ISS) and to estimate...

    Authors: Mônica Maria Teixeira, Maria de Fátima Haueisen Sander Diniz, Janice Sepúlveda Reis, Teresa Cristina Abreu Ferrari, Maria Goretti Bravim de Castro, Bruna Polonio Teixeira, Isabella Cristina da Silva Arantes, Danielle Marques Bicalho and Rodrigo Bastos Fóscolo
    Citation: Diabetology & Metabolic Syndrome 2014 6:131
    Content type: Research Published on:

  24. Metabolic syndrome is associated with an increased risk of cardiovascular and hepatic complications. Oxidative stress in metabolic tissues has emerged as a universal feature of metabolic syndrome and its co-mo...

    Authors: Nathalie Auberval, Stéphanie Dal, William Bietiger, Michel Pinget, Nathalie Jeandidier, Elisa Maillard-Pedracini, Valérie Schini-Kerth and Séverine Sigrist
    Citation: Diabetology & Metabolic Syndrome 2014 6:130
    Content type: Research Published on:

  25. The two primary pathophysiological characteristics of patients with type 2 diabetes mellitus (T2DM) are insulin resistance (IR) and beta cell dysfunction. It has been proposed that the development of IR is sec...

    Authors: Jesús Zacarías Villarreal-Pérez, Jesús Zacarías Villarreal-Martínez, Fernando Javier Lavalle-González, María del Rosario Torres-Sepúlveda, Consuelo Ruiz-Herrera, Ricardo Martín Cerda-Flores, Erik Rubén Castillo-García, Irám Pablo Rodríguez-Sánchez and Laura Elia Martínez de Villarreal
    Citation: Diabetology & Metabolic Syndrome 2014 6:129
    Content type: Research Published on:

  26. In patients with Latent Autoimmune Diabetes in Adults (LADA) a lower body mass index was reported compared with classical type 2 diabetes (T2D), and was found to be associated with a faster progression to insu...

    Authors: Giovanni Mario Pes, Alessandro Palmerio Delitala, Giuseppe Delitala, Alessandra Errigo, Salvatore Costantino and Giuseppe Fanciulli
    Citation: Diabetology & Metabolic Syndrome 2014 6:128
    Content type: Research Published on:

  27. Fasting insulin (FI), fasting glucose (FG), systolic blood pressure (SBP), high density lipoproteins (HDL), triacylglycerides (TAG), and body mass index (BMI) are well-known risk factors for type 2 diabetes. R...

    Authors: J A D Ranga Niroshan Appuhamy, Ermias Kebreab, Mitchell Simon, Rickey Yada, Larry P Milligan and James France
    Citation: Diabetology & Metabolic Syndrome 2014 6:127
    Content type: Research Published on:

  28. Type 2 diabetes mellitus is the most common metabolic disorder and has considerable impact on quality of life. Treatment of DM2 is complex and adherence to treatment requires sophisticated cognition which incl...

    Authors: Simone H de Castro, Gilberto N O Brito and Marilia B Gomes
    Citation: Diabetology & Metabolic Syndrome 2014 6:126
    Content type: Research Published on:

  29. Type 1 diabetes mellitus in pregnant women is associated with an increased risk of congenital malformations, obstetric complications, neonatal morbidity, and mortality. Our aim was to evaluate which factors fr...

    Authors: Bogdan Timar, Romulus Timar, Alin Albai, Dana Stoian, Razvan Nitu and Marius Craina
    Citation: Diabetology & Metabolic Syndrome 2014 6:125
    Content type: Research Published on:

  31. The global burden of diabetes mellitus and other chronic diseases is high, and 80% of those with diabetes now live in low and middle income countries. Yet, little information is available regarding prevalence ...

    Authors: Maria Inês Schmidt, Juliana F Hoffmann, Maria de Fátima Sander Diniz, Paulo A Lotufo, Rosane Härter Griep, Isabela M Bensenor, José G Mill, Sandhi Maria Barreto, Estela M L Aquino and Bruce B Duncan
    Citation: Diabetology & Metabolic Syndrome 2014 6:123
    Content type: Research Published on:

  32. The worldwide increase of diabetes, a long duration, slow progression disease, impacts health care costs. The aim of this study was to estimate, from the society’s perspective, the annual cost per patient with...

    Authors: Natalie Botelho Borges, Marcos Bosi Ferraz and Antonio Roberto Chacra
    Citation: Diabetology & Metabolic Syndrome 2014 6:122
    Content type: Research Published on:

  33. Current literature has elucidated a new phenotype, metabolically healthy obese (MHO), with risks of cardiovascular disease similar to that of normal weight individuals. Few studies have examined the MHO phenot...

    Authors: Lara Roberson, Sameer Shaharyar, Ehimen Aneni, Wladimir Freitas, Michael Blaha, Arthur Agatston, Roger Blumenthal, Raul D Santos, Hamid Feiz, Khurram Nasir and Andrei Sposito
    Citation: Diabetology & Metabolic Syndrome 2014 6:121
    Content type: Short report Published on:

  34. Gestational diabetes mellitus (GDM) is associated with cardiovascular diseases; however, the relationship between epicardial fat thickness (EFT) and GDM remains unclear. The present study evaluates and compare...

    Authors: Gökay Nar, Sinan Inci, Gökhan Aksan, Oguz Kağan Unal, Rukiye Nar and Korhan Soylu
    Citation: Diabetology & Metabolic Syndrome 2014 6:120
    Content type: Research Published on:

  36. The objective was to evaluate the muscle glucose metabolism in rats fed a fructose-rich diet after fetal protein malnutrition, at rest and after acute physical exercise at maximal lactate steady-state intensity.

    Authors: Lucieli T Cambri, Carla Ribeiro, José D Botezelli, Ana C Ghezzi and Maria AR Mello
    Citation: Diabetology & Metabolic Syndrome 2014 6:118
    Content type: Research Published on:

  37. The identification of sex-based disparities in the use of effective medications in high-risk populations can lead to interventions to minimize disparities in health outcomes. The objective of this study was to...

    Authors: Sonia Butalia, Adriane M Lewin, Scot H Simpson, Kaberi Dasgupta, Nadia Khan, Louise Pilote, Jeffrey A Johnson, William A Ghali and Doreen M Rabi
    Citation: Diabetology & Metabolic Syndrome 2014 6:117
    Content type: Research Published on:

  38. Recent studies have associated neck circumference (NC) with insulin resistance (IR). We examined whether such relation was modified by other metabolic risk factors.

    Authors: Jun Liang, Fei Teng, Xuekui Liu, Caiyan Zou, Yu Wang, Lianjun Dou, Zilin Sun and Lu Qi
    Citation: Diabetology & Metabolic Syndrome 2014 6:116
    Content type: Research Published on:

  39. It has been recognized that reduction of abdominal visceral fat and subcutaneous fat are associated with improvement in insulin-resistance (IR) after weight loss. However, few studies have investigated the cor...

    Authors: Kae-Woei Liang, I-Chen Tsai, Wen-Jane Lee, Shih-Yi Lin, Wen-Lieng Lee, I-Te Lee, Chia-Po Fu, Jun-Sing Wang and Wayne H-H Sheu
    Citation: Diabetology & Metabolic Syndrome 2014 6:115
    Content type: Research Published on:

  40. The aim of this study was to investigate the relationship between changes in serum ferritin concentrations and the development of metabolic syndrome (MetS) and its components over a 6.5 year follow-up period i...

    Authors: Päivi Hämäläinen, Juha Saltevo, Hannu Kautiainen, Pekka Mäntyselkä and Mauno Vanhala
    Citation: Diabetology & Metabolic Syndrome 2014 6:114
    Content type: Research Published on:

  41. Bezafibrate is mainly used to treat hypertriglyceridemia. Studies have reported that bezafibrate also improves type 2 diabetes mellitus, but the mechanism has not been fully elucidated. We performed euglycemic...

    Authors: Hideki Shiochi, Tsuyoshi Ohkura, Yohei Fujioka, Keisuke Sumi, Naoya Yamamoto, Risa Nakanishi, Kazuhiko Matsuzawa, Schoichiro Izawa, Hiroko Ohkura, Kazuoki Inoue, Etsuko Ueta, Masahiko Kato, Shin-ichi Taniguchi and Kazuhiro Yamamoto
    Citation: Diabetology & Metabolic Syndrome 2014 6:113
    Content type: Research Published on:

  42. Metabolic syndrome (MetS) has a huge impact on public health, and today lifestyle interventions remain the primary mode for MetS therapy. It is therefore important to elucidate the possible preventive effects ...

    Authors: Christine Tørris, Marianne Molin and Milada Cvancarova Småstuen
    Citation: Diabetology & Metabolic Syndrome 2014 6:112
    Content type: Review Published on:

  43. Despite the increasing prevalence of metabolic syndrome among young adults, little is known about the awareness level of college students about this condition. The purpose of this study was to assess students’...

    Authors: Najat Yahia, Carrie Brown, Melyssa Rapley and Mei Chung
    Citation: Diabetology & Metabolic Syndrome 2014 6:111
    Content type: Research Published on:

  44. Glucagon-like peptide-1 (GLP-1) receptor agonists can maintain good glycemic control in some diabetic. Here we compared the clinical characteristics and parameters reflecting glucose metabolism at the time of ...

    Authors: Kenjiro Imai, Tetsuro Tsujimoto, Atsushi Goto, Maki Goto, Miyako Kishimoto, Ritsuko Yamamoto-Honda, Hiroshi Noto, Hiroshi Kajio and Mitsuhiko Noda
    Citation: Diabetology & Metabolic Syndrome 2014 6:110
    Content type: Research Published on:

  45. Asymmetric dimethylarginine (ADMA) is an endogenous competitive inhibitor of nitric oxide (NO) synthetase. Elevated ADMA reduces NO formation and is associated with endothelial dysfunction. The aims of this st...

    Authors: Muyesser Sayki Arslan, Sibel Turhan, Irem Dincer, Dilsa Mizrak, Demet Corapcioglu and Ramazan Idilman
    Citation: Diabetology & Metabolic Syndrome 2014 6:109
    Content type: Research Published on:

  46. We sought to determine the modifying effects of age and multimorbidity on the association between First Nations status and hospitalizations for diabetes-specific ambulatory care sensitive conditions (ACSC).

    Authors: David JT Campbell, Sarah L Lacny, Robert G Weaver, Braden J Manns, Marcello Tonelli, Cheryl Barnabe and Brenda R Hemmelgarn
    Citation: Diabetology & Metabolic Syndrome 2014 6:108
    Content type: Short report Published on:

  47. Peroxisome proliferator-activated receptor gamma coactivator-1α (PPARGC1A/ PGC-1α) is a ligand-activated transcription factor belonging to the nuclear hormone receptor superfamily. The activity of PGC-1α or ge...

    Authors: Hui-Hui Wu, Nai-Jia Liu, Zhen Yang, Xiao-Ming Tao, Yan-Ping Du, Xuan-Chun Wang, Bin Lu, Zhao-Yun Zhang, Ren-Ming Hu and Jie Wen
    Citation: Diabetology & Metabolic Syndrome 2014 6:107
    Content type: Research Published on:

  48. Galectin-3 is a family of soluble beta-galactoside-binding lectins that play many important regulatory roles in inflammation. Galectin-3-deficient mice have been shown to exhibit excess adiposity, hyperglycemi...

    Authors: Tsuyoshi Ohkura, Youhei Fujioka, Risa Nakanishi, Hideki Shiochi, Keisuke Sumi, Naoya Yamamoto, Kazuhiko Matsuzawa, Shoichiro Izawa, Hiroko Ohkura, Etsuko Ueta, Masahiko Kato, Eiji Miyoshi, Shin-ichi Taniguchi and Kazuhiro Yamamoto
    Citation: Diabetology & Metabolic Syndrome 2014 6:106
    Content type: Research Published on:

  49. Metabolic syndrome (MS) has been shown to increase the risk of breast cancer. Existing data suggest that the strength of metabolic syndrome-breast cancer link varies by intrinsic molecular subtype, but results...

    Authors: Immacolata Capasso, Emanuela Esposito, Michelino de Laurentiis, Nicola Maurea, Ernesta Cavalcanti, Gerardo Botti, Antonella Petrillo, Maurizio Montella, Massimiliano D’Aiuto, Carmela Coppola, Anna Crispo, Maria Grimaldi, Giuseppe Frasci, Alfredo Fucito, Gennaro Ciliberto and Giuseppe D’Aiuto
    Citation: Diabetology & Metabolic Syndrome 2014 6:105
    Content type: Research Published on:

  50. The hypertensive, pro-inflammatory, obese state is strongly coupled to peripheral and hepatic insulin resistance (in composite termed metabolic syndrome [MS]). Hepatic pro-inflammatory pathways have been demon...

    Authors: Michael Ezrokhi, Shuqin Luo, Yelena Trubitsyna and Anthony H Cincotta
    Citation: Diabetology & Metabolic Syndrome 2014 6:104
    Content type: Research Published on:

    The Erratum to this article has been published in Diabetology & Metabolic Syndrome 2015 7:61

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Diabetology & Metabolic Syndrome

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