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Evaluation of restless legs syndrome symptoms in patients with and without the diagnosis of type 2 diabetes mellitus
Diabetology & Metabolic Syndrome volume 7, Article number: A89 (2015)
Restless legs syndrome (RLS) is a neurological sleep disorder. Literature suggests association between RLS and diabetes, but few studies have been done evaluating the association between these conditions.
Evaluate the prevalence of RLS symptoms in patients with and without the diagnosis of Type 2 Diabetes Mellitus (DM2).
Materials and methods
Case control study. 112 individuals were studied, 28 with DM2 (cases) and 84 without DM2 (controls), in a medical clinic specialities at Tubarão, Brazil. They answered a questionnaire with socio demographic questions, information about diabetes and to the four minimum criteria, defined by The International Restless Legs Syndrome Study Group (IRLSSG), for RLS diagnosis. Furthermore, they were subjected to the Epworth Sleepiness scale and the IRLSSG rating scale, both translated and validated to Portuguese[3, 4].
Among the cases, 21.4% presented RLS, compared to 14.3% in controls (p=0.269). The group with DM2 showed higher prevalence of Excessive daytime Sleepiness (EDS) (21.4% vs. 13.1%; p=0.219), and had higher scores in the IRLSSG rating scale (23,3±11,3 vs. 15,7±6,5; p=0.086). Correlating severity of RLS with glycemia, we obtained a Pearson correlation of 0.698 (p=0.003).
DM2 patients have a higher, but non-significant prevalence of RLS symptoms and EDS than the non-diabetics. It has been found a correlation between RLS severity and glycemia.
Innes KE, Selfe TK, Agarwal P: Restless legs syndrome and conditions associated with metabolic dysregulation, sympathoadrenal dysfunction, and cardiovascular disease risk: a systematic review. Sleep Med Rev. 2012, 16 (4): 309-39.
Allen RP, Picchietti D, Hening WA, Trenkwalder C, Walters AS, Montplaisi J, et al: Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health. Sleep Med. 2003, 4 (2): 101-19.
Bertolazi AN, Fagondes SC, Hoff LS, Pedro VD, Barreto M, Saldanha S, et al: Portuguese-language version of the Epworth sleepiness scale: validation for use in Brazil. J Bras Pneumol. 2009, 35 (9): 877-83.
Masuko AH, Carvalho LBC, Machado MAC, Morais JF, Prado LBF, Prado GF: Translation and validation into the Brazilian Portuguese of the restless legs syndrome rating scale of the International Restless Legs Syndrome Study Group. Arq Neuropsiquiatr. 2008, 66 (4): 832-6.
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Filho, A.O.B., Jung, G.A., Zoehler, L.V. et al. Evaluation of restless legs syndrome symptoms in patients with and without the diagnosis of type 2 diabetes mellitus. Diabetol Metab Syndr 7, A89 (2015) doi:10.1186/1758-5996-7-S1-A89
- Sleep Disorder
- Epworth Sleepiness Scale
- Excessive Daytime Sleepiness
- Syndrome Symptom
- Socio Demographic Question