Evaluation of restless legs syndrome symptoms in patients with and without the diagnosis of type 2 diabetes mellitus
© Filho et al. 2015
Published: 11 November 2015
Restless legs syndrome (RLS) is a neurological sleep disorder. Literature suggests association between RLS and diabetes, but few studies have been done evaluating the association between these conditions.
Evaluate the prevalence of RLS symptoms in patients with and without the diagnosis of Type 2 Diabetes Mellitus (DM2).
Materials and methods
Case control study. 112 individuals were studied, 28 with DM2 (cases) and 84 without DM2 (controls), in a medical clinic specialities at Tubarão, Brazil. They answered a questionnaire with socio demographic questions, information about diabetes and to the four minimum criteria, defined by The International Restless Legs Syndrome Study Group (IRLSSG), for RLS diagnosis. Furthermore, they were subjected to the Epworth Sleepiness scale and the IRLSSG rating scale, both translated and validated to Portuguese[3, 4].
Among the cases, 21.4% presented RLS, compared to 14.3% in controls (p=0.269). The group with DM2 showed higher prevalence of Excessive daytime Sleepiness (EDS) (21.4% vs. 13.1%; p=0.219), and had higher scores in the IRLSSG rating scale (23,3±11,3 vs. 15,7±6,5; p=0.086). Correlating severity of RLS with glycemia, we obtained a Pearson correlation of 0.698 (p=0.003).
DM2 patients have a higher, but non-significant prevalence of RLS symptoms and EDS than the non-diabetics. It has been found a correlation between RLS severity and glycemia.
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