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Prevalence and profile of diabetes kidney disease according to different diagnostic criteria in type 2 diabetes mellitus patients
Diabetology & Metabolic Syndrome volume 7, Article number: A28 (2015)
Diabetes kidney disease (DKD) is the worldwide leading cause of end-stage renal disease. Diagnostic criteria have been recently revised.
The aim of this study was to evaluate the prevalence and clinical profile of type 2 DM patients according to the employed definition of DKD: previous diagnostic criteria as compared to the present one.
Materials and methods
566 type 2 DM outpatients from the Endocrine Unit ambulatory were included. DKD was defined by the presence of elevated urinary albumin excretion alone (UAE; >14 mg/l) -previous definition- or by the presence of elevated UAE and/or reduced (<60 ml/min/1.73 m2) glomerular filtration rate (GFR) -present definition.
Mean age was 63±11 yrs., 37% men, 86% white, 10% smokers, DM duration 16 yrs. When evaluated by elevated UAE only, 50% of the patients presented DKD. Table 1 shows the profile of these patients (Fig 1). When defined by both UAE and GFR, 57% presented DKD, and Table 2 shows the profile of these patients (Fig 2).
DKD cases would be missed if only UAE is taken into account.
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Coelli, S., Soares, A.A., Duarte, C.K. et al. Prevalence and profile of diabetes kidney disease according to different diagnostic criteria in type 2 diabetes mellitus patients. Diabetol Metab Syndr 7, A28 (2015) doi:10.1186/1758-5996-7-S1-A28
- Diabetes Mellitus
- Kidney Disease
- Renal Disease
- Glomerular Filtration Rate