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Prevalence and profile of diabetes kidney disease according to different diagnostic criteria in type 2 diabetes mellitus patients

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Background

Diabetes kidney disease (DKD) is the worldwide leading cause of end-stage renal disease. Diagnostic criteria have been recently revised.

Objective

The aim of this study was to evaluate the prevalence and clinical profile of type 2 DM patients according to the employed definition of DKD: previous diagnostic criteria as compared to the present one.

Materials and methods

566 type 2 DM outpatients from the Endocrine Unit ambulatory were included. DKD was defined by the presence of elevated urinary albumin excretion alone (UAE; >14 mg/l) -previous definition- or by the presence of elevated UAE and/or reduced (<60 ml/min/1.73 m2) glomerular filtration rate (GFR) -present definition.

Results

Mean age was 63±11 yrs., 37% men, 86% white, 10% smokers, DM duration 16 yrs. When evaluated by elevated UAE only, 50% of the patients presented DKD. Table 1 shows the profile of these patients (Fig 1). When defined by both UAE and GFR, 57% presented DKD, and Table 2 shows the profile of these patients (Fig 2).

Figure 1
figure1

Clinical and laboratory characteristics of DKD patients according to the presence of elevated UAE only.

Figure 2
figure2

Clinical and laboratory characteristics of DKD patients according to the presence of elevated UAE and/or reduced GFR.

Conclusion

DKD cases would be missed if only UAE is taken into account.

Author information

Correspondence to Sabrina Coelli.

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This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Coelli, S., Soares, A.A., Duarte, C.K. et al. Prevalence and profile of diabetes kidney disease according to different diagnostic criteria in type 2 diabetes mellitus patients. Diabetol Metab Syndr 7, A28 (2015) doi:10.1186/1758-5996-7-S1-A28

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Keywords

  • Diabetes Mellitus
  • Albumin
  • Kidney Disease
  • Renal Disease
  • Glomerular Filtration Rate