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  1. Decreased expression of glucose transporter protein GLUT4, encoded by the solute carrier 2A4 (Slc2a4) gene, is involved in obesity-induced insulin resistance. Local tissue inflammation, by nuclear factor-κB (NFκB...

    Authors: Ana Cláudia Poletto, Aline David-Silva, Aline Pedro de Melo Yamamoto, Ubiratan Fabres Machado and Daniela Tomie Furuya
    Citation: Diabetology & Metabolic Syndrome 2015 7:18
  2. To evaluate the association between fasting glucose levels in women throughout pregnancy and the occurrence of gestational diabetes mellitus (GDM) and other pregnancy complications, macrosomia, and cesarean de...

    Authors: Gisele Seabra, Cláudia Saunders, Patrícia de Carvalho Padilha, Lenita Zajdenverg, Letícia Barbosa Gabriel da Silva and Marta Maria Antonieta de Souza Santos
    Citation: Diabetology & Metabolic Syndrome 2015 7:17
  3. The prevalence of obesity and Type 2 diabetes mellitus (T2DM) among children and adolescents is rising. Thyroid function has been associated with insulin resistance. There is scarce information about how thyro...

    Authors: José de Jesús Garduño-Garcia, Eneida Camarillo Romero, Ana Loe Ochoa, Socorro Romero-Figueroa, Gerardo Huitron Bravo, Roció Torres García, Patricia Montenegro-Morales and Hugo Mendieta-Zerón
    Citation: Diabetology & Metabolic Syndrome 2015 7:16
  4. Metabolic syndrome (MetS) is a constellation of symptoms used as a measure to identify patients at increased risk for cardiovascular disease, type 2 diabetes, and all-cause mortality. The results of prolonged ...

    Authors: Eduard Tiozzo, Janet Konefal, Sarah Adwan, Lynell A Martinez, Juan Villabona, Johanna Lopez, Stacy Cutrono, Syed Muhammad Ahsan Mehdi, Allan Rodriguez, Judi M Woolger and John E Lewis
    Citation: Diabetology & Metabolic Syndrome 2015 7:15
  5. Type 2 diabetes mellitus (T2D) is a complex disease associated with several chronic complications, including bone fragility and high fracture risk due to mechanisms not yet fully understood. The influence of t...

    Authors: Laura S Girão Lopes, Rubens Prado Schwartz, Bruno Ferraz-de-Souza, Maria Elizabeth Rossi da Silva, Pedro Henrique Silveira Corrêa and Márcia Nery
    Citation: Diabetology & Metabolic Syndrome 2015 7:13
  6. Obesity is characterized by low grade inflammation and an altered secretion of inflammatory cytokines from the adipose tissue. Weight loss has shown to reduce inflammation; however, changes in cytokine profile...

    Authors: Kirsten Katrine Lindegaard, Nils Bruun Jorgensen, Rasmus Just, Peter MH Heegaard and Sten Madsbad
    Citation: Diabetology & Metabolic Syndrome 2015 7:12
  7. Elevated serum ferritin levels have been reported to contribute to metabolic syndrome (MetS). We examined the association of serum ferritin levels with the development of MetS in a representative sample of Chi...

    Authors: Qin Tang, Zhenfang Liu, Yan Tang, Aihua Tan, Yong Gao, Zheng Lu, Qiuyan Wang, Yingchun Chen, Chunlei Wu, Haiying Zhang, Xiaobo Yang and Zengnan Mo
    Citation: Diabetology & Metabolic Syndrome 2015 7:11
  8. The Editors of Diabetology & Metabolic Syndrome would like to thank all of our reviewers, both external and Editorial Board Members, who have contributed to the journal in Volume 6 (2014) and whose valuable suppo...

    Authors: Daniel Giannella-Neto
    Citation: Diabetology & Metabolic Syndrome 2015 7:10
  9. To study the clinical and molecular characteristics of a sample of Brazilian patients with Congenital Hyperinsulinemic Hypoglycemia (CHH).

    Authors: Raphael Del Roio Liberatore Jr, Priscila Manzini Ramos, Gil Guerra Jr, Thais Della Manna, Ivani Novato Silva and Carlos Eduardo Martinelli Jr
    Citation: Diabetology & Metabolic Syndrome 2015 7:5
  10. Prospective studies have shown incidence rates of hypertension in diabetes mellitus to be three times that of subjects without diabetes mellitus. The reverse also applies, with the incidence of diabetes two to...

    Authors: Luciana Sayuri Sanada, Marcelo Rodrigo Tavares, Karina Laurenti Sato, Renata da Silva Ferreira, Milena Cardoso Maia Neubern, Jaci Ayrton Castania, Helio Cesar Salgado and Valéria Paula Sassoli Fazan
    Citation: Diabetology & Metabolic Syndrome 2015 7:9
  11. Low-dose aspirin is recommended to reduce the risk of cardiovascular disease. However, the questions with regard to primary prevention have been raised among patients with diabetes. We evaluated low-dose aspir...

    Authors: Ye-Jee Kim, Nam-Kyong Choi, Mi-Sook Kim, Joongyub Lee, Yoosoo Chang, Jong-Mi Seong, Sun-Young Jung, Ju-Young Shin, Ji-Eun Park and Byung-Joo Park
    Citation: Diabetology & Metabolic Syndrome 2015 7:8
  12. The metabolic syndrome (MS) is characterized by several cardiovascular risk factors and is associated with an increased incidence of diabetes, cardiovascular events and mortality. The prevalence of MS is incre...

    Authors: Fernanda de Carvalho Vidigal, Andréia Queiroz Ribeiro, Nancy Babio, Jordi Salas-Salvadó and Josefina Bressan
    Citation: Diabetology & Metabolic Syndrome 2015 7:6
  13. Metabolic syndrome (MetS) is associated with increased risks of diabetes and atherosclerotic cardiovascular disease. Whether central obesity (CeO) is a prerequisite for the diagnosis of MetS in the Internation...

    Authors: Ki-Bum Won, Hyuk-Jae Chang, Hiroyuki Niinuma, Koichiro Niwa, Kyewon Jeon, In-Jeong Cho, Chi-Young Shim, Geu-Ru Hong and Namsik Chung
    Citation: Diabetology & Metabolic Syndrome 2015 7:3
  14. Bilirubin can prevent lipid oxidation in vitro, but the association in vivo with oxidized low-density lipoprotein (Ox-LDL) levels has been poorly explored. Our aim is to the association of Ox-LDL with total bilir...

    Authors: Henrique Nascimento, Ana Inês Alves, Susana Coimbra, Cristina Catarino, Diana Gomes, Elsa Bronze-da-Rocha, Elísio Costa, Petronila Rocha-Pereira, Luísa Aires, Jorge Mota, Helena Ferreira Mansilha, Carla Rêgo, Alice Santos-Silva and Luís Belo
    Citation: Diabetology & Metabolic Syndrome 2015 7:4
  15. Self-monitoring of blood glucose (SMBG) has been recommended as a useful tool for improving glycemic control, but is still an underutilized strategy and most diabetic patients are not aware of the actions that...

    Authors: Daniel Dutra Romualdo Silva and Adriana Aparecida Bosco
    Citation: Diabetology & Metabolic Syndrome 2015 7:2
  16. Pregnant women with mild gestational hyperglycemia present high risk for hypertension, obesity and hyperglycemia, and appeared to reproduce the model of metabolic syndrome in pregnancy, with hyperinsulinemia a...

    Authors: Rafael Bottaro Gelaleti, Débora Cristina Damasceno, Paula Helena Ortiz Lima, Daisy Maria Favero Salvadori, Iracema de Mattos Paranhos Calderon, José Carlos Peraçoli and Marilza Vieira Cunha Rudge
    Citation: Diabetology & Metabolic Syndrome 2015 7:1
  17. Visceral adiposity contributes to cardiometabolic risk, and visceral adiposity index (VAI) had significant correlation with visceral adiposity. We aimed to explore whether VAI was associated with cardiac struc...

    Authors: Lu Han, Kai-li Fu, Jing Zhao, Zhi-hao Wang, Meng-xiong Tang, Jia Wang, Hui Wang, Yun Zhang, Wei Zhang and Ming Zhong
    Citation: Diabetology & Metabolic Syndrome 2014 6:143
  18. The purpose of this study was to carry out a cross-cultural adaptation to Brazilian Portuguese, validation, and comparison of two questionnaires to measure adherence in patients with type 1 diabetes. There are...

    Authors: Gabriela Heiden Teló, Martina Schaan de Souza and Beatriz D’Agord Schaan
    Citation: Diabetology & Metabolic Syndrome 2014 6:141
  19. Metabolic syndrome (MetS) is a clustering of five metabolic risk factors including abdominal obesity, elevated blood pressure, hypertriglyceridemia, low high-density lipoprotein cholesterol (HDL-C), and impair...

    Authors: Rumana J Khan, Samson Y Gebreab, Pia Riestra, Ruihua Xu and Sharon K Davis
    Citation: Diabetology & Metabolic Syndrome 2014 6:140
  20. Diabetic peripheral neuropathy (DPN) is one of the most common microvascular complications of diabetes. Glycemic variability could be an independent risk factor for diabetes complications in addition to averag...

    Authors: Feng Xu, Li-hua Zhao, Jian-bin Su, Tong Chen, Xue-qin Wang, Jin-feng Chen, Gang Wu, Yan Jin and Xiao-hua Wang
    Citation: Diabetology & Metabolic Syndrome 2014 6:139
  21. Type 2 diabetes mellitus has well known deleterious effects on coronary artery disease (CAD). The role of milder hyperglycemic states such as prediabetes (PD) on CAD is debatable. Glycated hemoglobin (HbA1c) h...

    Authors: Valdecira M Piveta, Celia S Bittencourt, Carolina SV Oliveira, Pedro Saddi-Rosa, Deyse M Meira, Fernando MA Giuffrida and André F Reis
    Citation: Diabetology & Metabolic Syndrome 2014 6:138
  22. The purpose of this research was to study the gene expression of interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), nuclear factor kappa B (NF-κB), vascular endothelial growth factor A (VEGF-A) and adipone...

    Authors: Larisa Litvinova, Dmitriy Atochin, Mariia Vasilenko, Nikolai Fattakhov, Pavel Zatolokin, Igor Vaysbeyn and Elena Kirienkova
    Citation: Diabetology & Metabolic Syndrome 2014 6:137
  23. Cardioprotective effects of Mediterranean-style diet have been shown. Instead of excluding foods, replacement or addition may facilitate compliance with impact on glucose metabolism of individuals at cardiomet...

    Authors: Camila Risso de Barros, Adriana Cezaretto, Maíra Ladeia Rodrigues Curti, Milena Monfort Pires, Luciana Dias Folchetti, Antonela Siqueira-Catania and Sandra Roberta Gouvea Ferreira
    Citation: Diabetology & Metabolic Syndrome 2014 6:136
  24. Ottawa Charter defined health as a resource for everyday life and as an important dimension of health related quality of life (HRqol). Diabetes and obesity have repeatedly been shown as diseases that diminish ...

    Authors: Concepción Vidal-Peracho, Maria Orosia Lucha-López, Ana Carmen Lucha-López, José Miguel Tricás-Moreno, Elena Estébanez-De Miguel and Luis Bernués-Vázquez
    Citation: Diabetology & Metabolic Syndrome 2014 6:135
  25. Coronary artery disease (CAD) is a major cardiovascular complication in diabetic patients. Despite the significant association between obesity and diabetes, the majority of the diabetic subjects are not obese ...

    Authors: Ki-Bum Won, Hyuk-Jae Chang, Hiroyuki Niinuma, Jimin Sung, In-Jeong Cho, Chi-Young Shim, Geu-Ru Hong, Young Jin Kim, Byung-Wook Choi and Namsik Chung
    Citation: Diabetology & Metabolic Syndrome 2014 6:134
  26. Irisin is a novel myokine secreted in response to peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) activation through exercise. The first-degree relatives (FDRs) of type 2 diabetes mellitus...

    Authors: Meili Yang, Peihong Chen, Hua Jin, Xinmiao Xie, Ting Gao, Lili Yang and Xuemei Yu
    Citation: Diabetology & Metabolic Syndrome 2014 6:133
  27. Adipocyte-derived factors and regulators likely contribute to the metabolic syndrome (MetS) in patients with central obesity. This study was undertaken to assess the contribution of leptin, adiponectin, and ac...

    Authors: Heno F Lopes, Richard L Klein, W Timothy Garvey, Theodore Goodfriend and Brent M Egan
    Citation: Diabetology & Metabolic Syndrome 2014 6:132
  28. To assess the presence of insulin resistance (IR) in patients with type 1 diabetes (T1DM) according to the estimated glucose disposal rate formula (eGDR) and the insulin sensitivity score (ISS) and to estimate...

    Authors: Mônica Maria Teixeira, Maria de Fátima Haueisen Sander Diniz, Janice Sepúlveda Reis, Teresa Cristina Abreu Ferrari, Maria Goretti Bravim de Castro, Bruna Polonio Teixeira, Isabella Cristina da Silva Arantes, Danielle Marques Bicalho and Rodrigo Bastos Fóscolo
    Citation: Diabetology & Metabolic Syndrome 2014 6:131
  29. Metabolic syndrome is associated with an increased risk of cardiovascular and hepatic complications. Oxidative stress in metabolic tissues has emerged as a universal feature of metabolic syndrome and its co-mo...

    Authors: Nathalie Auberval, Stéphanie Dal, William Bietiger, Michel Pinget, Nathalie Jeandidier, Elisa Maillard-Pedracini, Valérie Schini-Kerth and Séverine Sigrist
    Citation: Diabetology & Metabolic Syndrome 2014 6:130
  30. The two primary pathophysiological characteristics of patients with type 2 diabetes mellitus (T2DM) are insulin resistance (IR) and beta cell dysfunction. It has been proposed that the development of IR is sec...

    Authors: Jesús Zacarías Villarreal-Pérez, Jesús Zacarías Villarreal-Martínez, Fernando Javier Lavalle-González, María del Rosario Torres-Sepúlveda, Consuelo Ruiz-Herrera, Ricardo Martín Cerda-Flores, Erik Rubén Castillo-García, Irám Pablo Rodríguez-Sánchez and Laura Elia Martínez de Villarreal
    Citation: Diabetology & Metabolic Syndrome 2014 6:129
  31. In patients with Latent Autoimmune Diabetes in Adults (LADA) a lower body mass index was reported compared with classical type 2 diabetes (T2D), and was found to be associated with a faster progression to insu...

    Authors: Giovanni Mario Pes, Alessandro Palmerio Delitala, Giuseppe Delitala, Alessandra Errigo, Salvatore Costantino and Giuseppe Fanciulli
    Citation: Diabetology & Metabolic Syndrome 2014 6:128
  32. Fasting insulin (FI), fasting glucose (FG), systolic blood pressure (SBP), high density lipoproteins (HDL), triacylglycerides (TAG), and body mass index (BMI) are well-known risk factors for type 2 diabetes. R...

    Authors: J A D Ranga Niroshan Appuhamy, Ermias Kebreab, Mitchell Simon, Rickey Yada, Larry P Milligan and James France
    Citation: Diabetology & Metabolic Syndrome 2014 6:127
  33. Type 2 diabetes mellitus is the most common metabolic disorder and has considerable impact on quality of life. Treatment of DM2 is complex and adherence to treatment requires sophisticated cognition which incl...

    Authors: Simone H de Castro, Gilberto N O Brito and Marilia B Gomes
    Citation: Diabetology & Metabolic Syndrome 2014 6:126
  34. Type 1 diabetes mellitus in pregnant women is associated with an increased risk of congenital malformations, obstetric complications, neonatal morbidity, and mortality. Our aim was to evaluate which factors fr...

    Authors: Bogdan Timar, Romulus Timar, Alin Albai, Dana Stoian, Razvan Nitu and Marius Craina
    Citation: Diabetology & Metabolic Syndrome 2014 6:125
  35. The global burden of diabetes mellitus and other chronic diseases is high, and 80% of those with diabetes now live in low and middle income countries. Yet, little information is available regarding prevalence ...

    Authors: Maria Inês Schmidt, Juliana F Hoffmann, Maria de Fátima Sander Diniz, Paulo A Lotufo, Rosane Härter Griep, Isabela M Bensenor, José G Mill, Sandhi Maria Barreto, Estela M L Aquino and Bruce B Duncan
    Citation: Diabetology & Metabolic Syndrome 2014 6:123
  36. The worldwide increase of diabetes, a long duration, slow progression disease, impacts health care costs. The aim of this study was to estimate, from the society’s perspective, the annual cost per patient with...

    Authors: Natalie Botelho Borges, Marcos Bosi Ferraz and Antonio Roberto Chacra
    Citation: Diabetology & Metabolic Syndrome 2014 6:122
  37. Current literature has elucidated a new phenotype, metabolically healthy obese (MHO), with risks of cardiovascular disease similar to that of normal weight individuals. Few studies have examined the MHO phenot...

    Authors: Lara Roberson, Sameer Shaharyar, Ehimen Aneni, Wladimir Freitas, Michael Blaha, Arthur Agatston, Roger Blumenthal, Raul D Santos, Hamid Feiz, Khurram Nasir and Andrei Sposito
    Citation: Diabetology & Metabolic Syndrome 2014 6:121
  38. Gestational diabetes mellitus (GDM) is associated with cardiovascular diseases; however, the relationship between epicardial fat thickness (EFT) and GDM remains unclear. The present study evaluates and compare...

    Authors: Gökay Nar, Sinan Inci, Gökhan Aksan, Oguz Kağan Unal, Rukiye Nar and Korhan Soylu
    Citation: Diabetology & Metabolic Syndrome 2014 6:120
  39. The objective was to evaluate the muscle glucose metabolism in rats fed a fructose-rich diet after fetal protein malnutrition, at rest and after acute physical exercise at maximal lactate steady-state intensity.

    Authors: Lucieli T Cambri, Carla Ribeiro, José D Botezelli, Ana C Ghezzi and Maria AR Mello
    Citation: Diabetology & Metabolic Syndrome 2014 6:118
  40. The identification of sex-based disparities in the use of effective medications in high-risk populations can lead to interventions to minimize disparities in health outcomes. The objective of this study was to...

    Authors: Sonia Butalia, Adriane M Lewin, Scot H Simpson, Kaberi Dasgupta, Nadia Khan, Louise Pilote, Jeffrey A Johnson, William A Ghali and Doreen M Rabi
    Citation: Diabetology & Metabolic Syndrome 2014 6:117
  41. Recent studies have associated neck circumference (NC) with insulin resistance (IR). We examined whether such relation was modified by other metabolic risk factors.

    Authors: Jun Liang, Fei Teng, Xuekui Liu, Caiyan Zou, Yu Wang, Lianjun Dou, Zilin Sun and Lu Qi
    Citation: Diabetology & Metabolic Syndrome 2014 6:116
  42. It has been recognized that reduction of abdominal visceral fat and subcutaneous fat are associated with improvement in insulin-resistance (IR) after weight loss. However, few studies have investigated the cor...

    Authors: Kae-Woei Liang, I-Chen Tsai, Wen-Jane Lee, Shih-Yi Lin, Wen-Lieng Lee, I-Te Lee, Chia-Po Fu, Jun-Sing Wang and Wayne H-H Sheu
    Citation: Diabetology & Metabolic Syndrome 2014 6:115
  43. The aim of this study was to investigate the relationship between changes in serum ferritin concentrations and the development of metabolic syndrome (MetS) and its components over a 6.5 year follow-up period i...

    Authors: Päivi Hämäläinen, Juha Saltevo, Hannu Kautiainen, Pekka Mäntyselkä and Mauno Vanhala
    Citation: Diabetology & Metabolic Syndrome 2014 6:114
  44. Metabolic syndrome (MetS) has a huge impact on public health, and today lifestyle interventions remain the primary mode for MetS therapy. It is therefore important to elucidate the possible preventive effects ...

    Authors: Christine Tørris, Marianne Molin and Milada Cvancarova Småstuen
    Citation: Diabetology & Metabolic Syndrome 2014 6:112

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