A nonlinear relationship between the triglycerides to high-density lipoprotein cholesterol ratio and stroke risk: an analysis based on data from the China Health and Retirement Longitudinal Study

Table 6 Effect size of TG/HDL-C ratio on stroke in prespecified and exploratory subgroups

Characteristic	No of participants	HR (95% CI) P value	P for interaction
Age (years)			0.7958
< 65	7453	1.02 (0.99, 1.05) 0.1153
≥ 65	2711	1.03 (0.99, 1.07) 0.1305
Gender			0.3896
Male	4746	1.04 (1.00, 1.07) 0.0294
Female	5418	1.02 (0.99, 1.05) 0.2225
BMI (kg/m²)			0.8826
< 25	6936	1.03 (1.00, 1.06) 0.0791
≥ 25	3228	1.03 (0.99, 1.06) 0.1257
Smoking status			0.0331
Never smokers	6250	1.05 (1.01, 1.08) 0.0047
Ever smokers	882	1.02 (0.96, 1.09) 0.4545
Current smokers	3032	0.98 (0.94, 1.03) 0.4822
Drinking status			0.5347
Never drinkers	1384	0.99 (0.93, 1.06) 0.8557
Ever drinkers	6220	1.05 (1.02, 1.09) 0.0010
Current drinkers	2560	0.99 (0.94, 1.04) 0.5865
Physical activity			0.4156
No	3593	1.03 (1.00, 1.07) 0.0424
Yes	6571	1.02 (0.99, 1.05) 0.2286

The above model was adjusted for BMI, gender, age, drinking status, physical activity, smoking status, drugs for cardiovascular prevention, hypertension, FPG, TC, CRP, LDL-C, Scr, HbA1c, Cystatin C, and UA
The model is not adjusted for the stratification variable in each case

ISSN: 1758-5996