Parameter | SUA Q1 | SUA Q2 | SUA Q3 | SUA Q4 | P |
---|---|---|---|---|---|
n | 114 | 117 | 113 | 114 | |
Male, n (%) | 46 (40.35) | 72 (62.54) | 88 (78.57) | 96 (84.21) | < 0.001 |
Age (year) | 58.72 ± 10.75 | 56.15 ± 11.59 | 52.21 ± 14.70# | 51.27 ± 13.24#* | < 0.001 |
Weight (kg) | 65.11 ± 10.55 | 68.14 ± 12.17 | 73.02 ± 12.90#* | 76.77 ± 12.34#* | < 0.001 |
BMI (kg/m2) | 24.05 ± 3.16 | 24.71 ± 3.66 | 25.35 ± 3.18# | 26.32 ± 3.63#* | < 0.001 |
Diabetes duration (year) | 9.87 ± 7.89 | 8.99 ± 6.65 | 6.97 ± 6.75# | 7.60 ± 7.82 | 0.005 |
Smokingn (%) | 19 (16.96) | 33 (29.73) | 43 (40.95) | 40 (38.83) | < 0.001 |
SBP (mmHg) | 134.18 ± 19.73 | 132.66 ± 15.57 | 135.29 ± 16.90 | 135.19 ± 18.73 | 0.547 |
DBP (mmHg) | 78.58 ± 13.55 | 78.62 ± 9.20 | 80.95 ± 11.20 | 81.67 ± 13.31 | 0.261 |
SUA (µmol/L) | 209.95 ± 33.66 | 281.43 ± 15.01# | 341.90 ± 22.35#* | 451.60 ± 65.34#*∆ | < 0.001 |
BUN (mmol/L) | 5.28 ± 1.32 | 5.74 ± 1.33 | 5.58 ± 1.47 | 6.92 ± 4.88#*∆ | < 0.001 |
SCr (µmol/L) | 49.50 ± 13.20 | 56.66 ± 16.25# | 59.58 ± 15.30# | 69.99 ± 19.44#*∆ | < 0.001 |
TC (mmol/L) | 4.28 (3.47, 5.01) | 4.47 (3.73, 5.09) | 4.43 (3.72, 5.08) | 4.47 (3.89, 5.34) | 0.359 |
TG (mmol/L) | 1.17 (0.81, 1.70) | 1.43 (0.96, 1.80) | 1.67 (1.23, 2.77)#* | 2.00 (1.17, 3.03)#* | < 0.001 |
HDL (mmol/L) | 1.17 (1.00, 1.43) | 1.10 (0.93, 1.31)# | 0.99 (0.89, 1.14)#* | 0.94 (0.84, 1.20)#* | < 0.001 |
LDL (mmol/L) | 2.60(1.96, 3.24) | 2.80 (2.12, 3.41) | 2.72 (2.15, 3.32) | 2.74 (2.13, 3.29) | 0.629 |
FBG (mmol/L) | 7.94 ± 2.96 | 7.54 ± 2.81 | 7.69 ± 2.53 | 7.41 ± 2.67 | 0.425 |
HbA1c (%) | 9.51 ± 2.22 | 9.25 ± 2.01 | 8.96 ± 2.24 | 8.27 ± 1.86#* | < 0.001 |
TBR (%) | 0.00 (0.00, 0.20) | 0.00 (0.00, 0.00) | 0.00 (0.00, 0.00) | 0.00 (0.00, 0.00) | 0.136 |
TIR (%) | 63.35 (42.80, 83.07) | 67.62 (37.93, 80.46) | 67.27 (42.11, 83.69) | 79.03 (59.89, 89.16)#*∆ | < 0.001 |
TAR (%) | 34.97 (16.59, 56.81) | 31.92 (18.38, 62.07) | 30.47 (15.59, 57.89) | 20.97 (10.19, 39.77)#*∆ | < 0.001 |
MAGE (mmol/L) | 4.86 (3.94, 5.92) | 4.85 (3.71, 6.11) | 4.20 (3.28, 5.22)#* | 3.58 (2.92, 4.82)#* | < 0.001 |
SD (mmol/L) | 2.54 (2.06, 3.45) | 2.65 (1.97, 3.18) | 2.16 (1.74, 2.73)#* | 1.95 (1.45, 2.61)#* | < 0.001 |
ADRR (mmol/L) | 24.50 (17.96, 34.65) | 24.37 (18.45, 36.93) | 22.49 (15.20, 30.28)#* | 18.39 (11.53, 27.01)#* | < 0.001 |
MODD (mmol/L) | 2.29 (1.82, 3.23) | 2.27 (1.61, 3.06) | 1.94 (1.41, 2.69)# | 1.74 (1.10, 2.31)#* | < 0.001 |
M value (mmol/L) | 9.42 (4.23, 19.81) | 8.36 (4.35, 18.42) | 7.37 (3.12, 14.86) | 4.29 (2.03, 11.13)#* | < 0.001 |
Treatment, n (%) | 0.574 | ||||
No treatment | 95 (84.82) | 93 (79.49) | 88 (77.88) | 94 (81.74) | |
OHA | 89 (79.46) | 90 (76.92) | 88 (77.88) | 79 (68.70) | |
Insulin | 53 (47.32) | 51 (43.59) | 57 (50.44) | 51 (44.35) | |
OHA and insulin | 48 (42.86) | 41 (38.04) | 52 (46.02) | 44 (38.26) |