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Table 2 Cox regression analyses for the association between TyG index, TyG-BMI, TG/HDL-C ratio, MetS-IR and incident DM in different models

From: Predictive value of insulin resistance surrogates for the development of diabetes in individuals with baseline normoglycemia: findings from two independent cohort studies in China and Japan

 

Hazard ratios (95% confidence interval) (Per SD increase)

TyG index

TyG-BMI

TG/HDL-C ratio

MetS-IR

All cohort

 Model 1

2.09 (2.02, 2.16)

2.17 (2.10, 2.24)

1.65 (1.59, 1.71)

1.92 (1.86, 1.98)

 Model 2

2.00 (1.93, 2.07)

2.09 (2.02, 2.16)

1.57 (1.51, 1.63)

1.84 (1.78, 1.90)

 Model 3

1.33 (1.28, 1.38)

1.51 (1.45, 1.57)

1.37 (1.31, 1.44)

1.51 (1.45, 1.57)

 

E value = 1.99

E value = 2.39

E value = 2.08

E value = 2.39

Races (model 1)

 Chinese cohort

2.09 (2.02, 2.17)

2.13 (2.06, 2.20)

1.61 (1.55, 1.67)

1.86 (1.80, 1.92)

 Japanese cohort

2.15 (1.93, 2.40)

2.54 (2.31, 2.79)

1.94 (1.76, 2.15)

2.38 (2.19, 2.60)

Races (model 2)

 Chinese cohort

2.01 (1.93, 2.08)

2.05 (1.98, 2.12)

1.54 (1.48, 1.60)

1.78 (1.73, 1.85)

 Japanese cohort

2.03 (1.81, 2.26)

2.54 (2.28, 2.83)

1.85 (1.67, 2.04)

2.33 (2.12, 2.57)

Races (model 3)

 Chinese cohort

1.33 (1.28, 1.39)

1.48 (1.42, 1.54)

1.37 (1.31, 1.44)

1.47 (1.41, 1.53)

 

E value = 1.99

E value = 2.32

E value = 2.08

E value = 2.3

 Japanese cohort

1.23 (1.07, 1.40)

1.79 (1.57, 2.04)

1.26 (1.08, 1.47)

1.86 (1.62, 2.13)

 

E value = 1.76

E value = 2.98

E value = 1.83

E value = 3.12

  1. Model 1 adjusted for gender, age, race and height
  2. Model 2 adjusted for gender, age, race, height, smoking status, SBP and DBP
  3. Model 3 adjusted for gender, age, race, height, smoking status, SBP, DBP, FPG, HDL-C, LDL-C and ALT
  4. Race variables are not adjusted in the grouping of races