Variables | T1 | T2 | T3 | P-value |
---|---|---|---|---|
(0.74<) | (0.74–0.93) | (> 0.93) | ||
Sample size, n | 1339 | 1339 | 1340 | |
Demography | ||||
Age, years | 57.47 ± 7.93 | 56.43 ± 8.21 | 57.29 ± 8.09 | 0.002 |
Sex | 0.013 | |||
Women | 423 (31.59%) | 361 (26.96%) | 420 (31.34%) | |
Men | 916 (68.41%) | 978 (73.04%) | 920 (68.66%) | |
Current smoking | 451 (33.68%) | 492 (36.74%) | 397 (29.63%) | < 0.001 |
Current drinking | 313 (23.38%) | 335 (25.02%) | 278 (20.75%) | 0.030 |
Heart rate, beats/min | 79.84 ± 12.76 | 79.77 ± 13.00 | 82.61 ± 14.33 | < 0.001 |
BMI, kg/m2 | 26.49 ± 3.69 | 26.65 ± 3.61 | 26.18 ± 3.65 | 0.003 |
SBP, mmHg | 141.48 ± 22.36 | 145.16 ± 23.43 | 149.49 ± 25.38 | < 0.001 |
DBP, mmHg | 84.81 ± 13.82 | 87.23 ± 14.52 | 88.45 ± 15.13 | < 0.001 |
Previous history | ||||
Hypertension | 550 (41.08%) | 535 (39.96%) | 622 (46.42%) | 0.001 |
Coronary artery disease | 111 (8.29%) | 87 (6.50%) | 106 (7.91%) | 0.181 |
Diabetes mellitus | 265 (19.79%) | 206 (15.38%) | 361 (26.94%) | < 0.001 |
Previous haemorrhagic stroke | 37 (2.76%) | 34 (2.54%) | 39 (2.91%) | 0.839 |
Previous ischemic stroke | 127 (9.48%) | 99 (7.39%) | 116 (8.66%) | 0.149 |
Biochemical indexes | ||||
WBC, 10^9/L | 7.51 ± 2.23 | 7.60 ± 2.34 | 8.36 ± 2.66 | < 0.001 |
RBC, 10^12/L | 4.77 ± 0.53 | 4.80 ± 0.51 | 4.76 ± 0.57 | 0.121 |
HB, g/L | 143.61 ± 17.43 | 146.18 ± 17.02 | 146.43 ± 18.74 | < 0.001 |
PLT, 10^9/L | 246.81 ± 63.38 | 236.15 ± 61.75 | 235.12 ± 64.35 | < 0.001 |
ALT, U/L | 22.00 (16.00–33.00) | 23.00 (16.50–33.00) | 23.00 (16.00–33.00) | 0.411 |
AST, U/L | 19.00 (16.00-24.90) | 20.00 (16.00-24.91) | 20.00 (16.00–26.00) | 0.194 |
Albumin/globulin ratio | 1.44 ± 0.27 | 1.48 ± 0.27 | 1.42 ± 0.27 | < 0.001 |
Serum creatinine, µmol/L | 70.28 ± 27.02 | 71.51 ± 26.78 | 72.74 ± 30.74 | 0.078 |
Uric acid | 319.68 ± 90.81 | 331.72 ± 92.18 | 321.81 ± 98.98 | 0.002 |
Serum potassium, mEq/L | 3.85 ± 0.39 | 3.86 ± 0.41 | 3.88 ± 0.41 | 0.076 |
Serum sodium, mEq/L | 140.33 ± 3.27 | 140.28 ± 3.11 | 139.30 ± 4.09 | < 0.001 |
Total cholesterol, mmol/L | 4.05 ± 1.07 | 4.23 ± 1.10 | 4.37 ± 1.14 | < 0.001 |
Triglyceride, mmol/L | 1.39 (1.04–1.92) | 1.52 (1.10–2.13) | 1.62 (1.13–2.45) | < 0.001 |
HDL-C, mmol/L | 0.96 ± 0.25 | 0.99 ± 0.26 | 1.01 ± 0.30 | < 0.001 |
LDL-C, mmol/L | 2.40 ± 0.90 | 2.48 ± 0.91 | 2.52 ± 0.94 | 0.003 |
HbA1c, % | 6.89 ± 1.71 | 6.57 ± 1.63 | 7.21 ± 2.13 | < 0.001 |
Admission blood glucose, mmol/L | 5.19 ± 1.57 | 6.47 ± 2.23 | 10.94 ± 5.70 | < 0.001 |
Type of stroke, n (%) | 0.007 | |||
Ischemic stroke | 1031 (77.00%) | 1043 (77.89%) | 1018 (75.97%) | |
Haemorrhagic stroke | 308 (23.00%) | 296 (22.11%) | 322 (24.03%) |