Prognostic significance of the stress hyperglycemia ratio and admission blood glucose in diabetic and nondiabetic patients with spontaneous intracerebral hemorrhage

Table 2 Hazard ratio (HR) for all-cause 30-day or 1-year mortality of SHR, ABG and HbA1C in the whole cohort

Variables	30-day mortality						1-year mortality
	Unadjusted model			Adjusted model ^d			Unadjusted model			Adjusted model ^e
	HR(95% CI)	p value	p-trend	HR(95% CI)	p value	p-trend	HR(95% CI)	p value	p-trend	HR(95% CI)	p value	p-trend
SHR
Continuous variable per unit	3.41 (2.64,4.40)	< 0.001		2.78 (2.00,3.86)	< 0.001		2.65 (2.10,3.33)	< 0.001		2.00 (1.52,2.64)	< 0.001
Quantile ^a			< 0.001			< 0.001			< 0.001			< 0.001
Q1 (n = 205)	Ref						Ref
Q2 (n = 204)	0.96 (0.53,1.72)	0.884		1.03 (0.57,1.88)	0.920		0.93 (0.63,1.37)	0.698		0.96 (0.64,1.44)	0.851
Q3 (n = 209)	1.59 (0.94,2.68)	0.084		1.63 (0.94,2.82)	0.080		1.28 (0.89,1.85)	0.179		1.26 (0.86,1.84)	0.233
Q4 (n = 204)	1.78 (1.06,2.98)	0.028		1.88 (1.08,3.27)	0.027		1.19 (0.82,1.73)	0.356		1.23 (0.82,1.83)	0.315
Q5 (n = 206)	3.95 (2.48,6.31)	< 0.001		3.33 (2.01,5.51)	< 0.001		2.49 (1.78,3.48)	< 0.001		2.09 (1.46,3.00)	< 0.001
ABG
Continuous variable per unit	1.01 (1.00,1.02)	< 0.001		1.00 (1.00,1.01)	< 0.001		1.01 (1.00,1.02)	< 0.001		1.01 (1.00,1.01)	< 0.001
Quantile ^b			< 0.001			< 0.001			< 0.001			< 0.001
Q1 (n = 206)	Ref						Ref
Q2 (n = 215)	0.73 (0.42,1.30)	0.289		0.81 (0.45,1.46)	0.484		0.91 (0.62,1.33)	0.613		1.06 (0.71,1.56)	0.789
Q3 (n = 197)	1.65 (1.02,2.70)	0.043		1.35 (0.89,2.31)	0.119		1.09 (0.75,1.60)	0.641		1.27 (0.85,1.89)	0.243
Q4 (n = 208)	1.92 (1.20,3.07)	0.006		1.58 (0.96,2.59)	0.073		1.57 (1.11,2.22)	0.011		1.29 (0.90,1.86)	0.171
Q5 (n = 202)	2.51 (1.59,3.97)	< 0.001		2.21 (1.37,3.57)	0.001		1.97 (1.40,2.77)	< 0.001		1.79 (1.26,2.54)	0.001

^a SHR: Q1 (≤ 0.863), Q2 (0.863–0.978), Q3 (0.978–1.112), Q4 (1.112–1.314), Q5 (>1.314)
^b Glucose: Q1 (≤ 99.4), Q2 (99.4–116), Q3 (116–134), Q4 (134–167), Q5 (>167)
^c HbA1C: Q1 (≤ 5.3), Q2 (5.3–5.6), Q3 (5.6–5.9), Q4 (5.9–6.6), Q5 (>6.6)
^d Adjusted model was adjusted for the variables with a p value < 0.01 in the univariable Cox regression, including gender, age, heart rate, mean arterial pressure, respiratory rate, body temperature, SpO₂, Glasgow Coma Scale, white blood cell count, neutrophil percentage, lymphocyte percentage, hemoglobin, red blood cell distribution width, serum calcium, serum sodium, creatinine, blood urea nitrogen, aspartate aminotransferase, and bilirubin
^e Adjusted model was adjusted for the variables with a p value < 0.01 in the univariable Cox regression, including gender, age, myocardial infarct, congestive heart failure, renal disease, heart rate, mean arterial pressure, respiratory rate, body temperature, SpO₂, Glasgow Coma Scale, white blood cell count, lymphocyte percentage, hemoglobin, red blood cell distribution width, serum calcium, serum sodium, creatinine, blood urea nitrogen, aspartate aminotransferase, bilirubin, and prothrombin time

ISSN: 1758-5996