Table 1 Characteristics of AIS patients undergoing MT based on the GAR
| Â | Group 1 | Group 2 | Group 3 | Group 4 | P |
|---|---|---|---|---|---|
|  | (n = 136) | (n = 141) | (n = 139) | (n = 137) |  |
General data | |||||
 Age, Median, (IQR) | 61 (52–71) | 62 (54–71) | 67 (60–77) | 69 (61–79) |  < 0.001 |
 Male, n (%) | 106 (77.9%) | 100 (70.9%) | 77 (55.4%) | 85 (62.0%) |  < 0.001 |
 Smoking, n (%) | 73 (53.7%) | 57 (40.4%) | 43 (30.9%) | 35 (25.5%) |  < 0.001 |
Medical history, n (%) | |||||
 Atrial fibrillation, n (%) | 15 (11.0%) | 18 (12.8%) | 37 (26.6%) | 31 (22.6%) | 0.001 |
 Previous TIA/stroke, n (%) | 12 (8.82%) | 27 (19.1%) | 26 (18.7%) | 46 (33.6%) |  < 0.001 |
 Cardiovascular disease, n (%) | 11 (8.09%) | 22 (15.6%) | 19 (13.7%) | 23 (16.8%) | 0.158 |
 Diabetes mellitus, n (%) | 26 (19.1%) | 32 (22.7%) | 26 (18.7%) | 52 (38.0%) |  < 0.001 |
 Hypertensive disease, n (%) | 66 (48.5%) | 63 (44.7%) | 75 (54.0%) | 90 (65.7%) | 0.003 |
Clinical characteristics | |||||
 Systolic pressure, Median, (IQR) | 130 (117–142) | 134 (119–147) | 136 (120–149) | 140 (129–157) | 0.001 |
 Diastolic pressure, Mean ± SD | 75 ± 13 | 77 ± 15 | 77 ± 17 | 79 ± 15 | 0.150 |
 Median NIHSS score at admission (IQR) | 12 (8–17) | 15 (10–19) | 16 (12–20) | 17 (12–21) |  < 0.001 |
 Median NIHSS score at discharge (IQR) | 6 (3–12) | 7 (3–15) | 6 (2–13) | 8 (3–13) | 0.550 |
 Median Pre-stroke mRS (range) | 0 (0–3) | 0 (0–3) | 0 (0–3) | 0 (0–3) | 0.168 |
 Median Onset-to-reperfusion time, (min), (IQR) | 481(277–741) | 395 (303–629) | 354 (274–520) | 369 (268–585) | 0.013 |
Stroke subtypes based on TOAST classification | Â | Â | Â | Â | 0.362 |
 Atherosclerosis n (%) | 79 (58.1) | 85 (60.3) | 70 (50.4) | 89 (65.0) |  |
 Cardioembolism, n (%) | 48 (35.3) | 45 (31.9) | 55 (39.6) | 41 (29.9) |  |
 Other determined etiology, n (%) | 5 (3.7) | 7 (3.7) | 5 (3.6) | 3 (2.2) |  |
 Undetermined etiology, n (%) | 4 (2.9) | 4 (2.9) | 9 (6.5) | 4 (2.9) |  |
 Baseline ASPECTS of anterior circulation strokes, Median, (IQR) | 8 (6–10) | 9 (7–10) | 8 (6–10) | 8 (7–10) | 0.519 |
 Baseline ASPECTS of posterior circulation strokes, Median, (IQR) | 7 (4–9) | 8 (6–10) | 8 (6–9) | 7 (5–10) | 0.604 |
Laboratory data | |||||
 Fasting plasma -glucose, mmol/l | 4.97 (4.42–5.46) | 6.20 (5.75–6.82) | 7.27 (6.82–8.01) | 11.11 (8.98–14.42) |  < 0.001 |
 Glycated hemoglobin, % | 5.8 (5.5–6.4) | 6.0 (5.6–6.5) | 5.8 (5.5–6.3) | 6.2 (5.6–7.6) | 0.007 |
 Hemoglobin, g/l | 135 (121–146) | 132 (119–144) | 131 (115–143) | 131 (119–143) | 0.308 |
 GAR index | 0.85 (0.76–0.90) | 1.03 (0.98–1.08) | 1.25 (1.18–1.32) | 1.65 (1.50–1.94) |  < 0.001 |
 HDL cholesterol, mmol/l | 0.95 (0.80–1.09) | 0.98 (0.85–1.12) | 0.98 (0.82–1.17) | 1.03 (0.83–1.17) | 0.199 |
 LDL cholesterol, mmol/l | 2.57 (1.99–3.23) | 2.73 (2.16–3.34) | 2.59 (1.98–3.13) | 2.59 (1.91–3.34) | 0.428 |
 Triglycerides, mmol/l | 1.23 (0.88–1.70) | 1.20 (0.86–1.68) | 1.19 (0.78–1.58) | 1.11 (0.76–1.72) | 0.418 |
 Total cholesterol, mmol/l | 4.47 ± 1.14 | 4.61 ± 1.14 | 4.36 ± 1.10 | 4.45 ± 1.22 | 0.339 |
 Homocysteine, umol/l | 9.10 (7.10–11.68) | 8.30 (6.25–10.40) | 8.50 (6.20–10.50) | 7.65 (6.20–10.30) | 0.005 |
 Serum creatinine, umol/l | 78.2 (63.8–90.9) | 72.0 (61.0–89.0) | 75.0 (62.0–91.2) | 73.5 (62.0–91.3) | 0.427 |
 hsCRP, mg/l | 3.78 (1.29–13.62) | 3.80 (1.13–14.72) | 5.60 (1.12–22.62) | 9.72 (1.45–33.42) | 0.016 |
 INR | 1.06 (1.01–1.12) | 1.11 (1.03–1.19) | 1.12 (1.05–1.24) | 1.11 (1.03–1.20) |  < 0.001 |
 IVT, n (%) | 25 (18.4%) | 46 (32.6%) | 46 (33.1%) | 28 (20.4%) | 0.004 |