Fig. 1

RYGB changes physiological parameters in db/m and db/db mice. A, Body weight. db/m and db/db mice were weighed after sham and RYGB surgery (n = 4–6). B, Whole appearance. C-F, Changes in food intake, water intake, fasting blood glucose and feeding blood glucose were monitored in db/m and db/db mice after sham and RYGB surgery weekly (n = 4–6). Daily average water intake and daily average food intake are shown on their right. G, Tail-cuff systolic blood pressure and diastolic blood pressure in db/m and db/db mice after sham and RYGB surgery (n = 5). The data are presented as the mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001