Fig. 2

Evolution of HbA_1c over the study period. a HbA_1c (in %) at different time points before and after index date (T₀). Red circles: PERT group. Blue triangles: control group. b Mean HbA_1c (in %) over the year prior and the year following T₀ in the PERT and control groups. Each dot or triangle represents a subject (n = 46 in the PERT group, 40 in the control group). c Intra-subject variability of HbA_1c in the PERT and control groups. Intra-subject variability of HbA_1c = mean HbA_1C of subject over the year following T₀ – mean HbA_1c of said subject over the year prior to T₀. Each dot or triangle represents a subject (n = 46 in the PERT group, 40 in the control group)