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Fig. 1 | Diabetology & Metabolic Syndrome

Fig. 1

From: Long noncoding RNA XIST promotes cell proliferation and migration in diabetic foot ulcers through the miR-126-3p/EGFR axis

Fig. 1

Changes in biochemical indices, pathological features, and gene expression in normal rats and rats with diabetic ulcers. (A) Image of the normal and diabetic rat groups. (B) Glucometer measurement of random blood glucose levels in the tail vein. (C) HE staining of the normal and diabetic ulcer groups (magnification: 20×; scale bar = 500 μm). Masson staining of skin tissues (magnification: 50×; scale bar = 200 μm). (D) The relative expression of lncRNA XIST, miR-126-3p, and EGFR determined via RT-qPCR. (E) The relative expression of EGFR determined via Western blots. (F) The expression of EGFR in skin tissues was assessed using IHC (magnification: 50×; scale bar = 200 μm) (magnification: 200×; scale bar = 50 μm). *P < 0.05, ***P < 0.001, ****P < 0.0001

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