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Table 5 Risk of T2DM with HTN according to baseline TyG in unadjusted and adjusted models for different levels of age, BMI, eGFR

From: A higher TyG index level is more likely to have enhanced incidence of T2DM and HTN comorbidity in elderly Chinese people: a prospective observational study from the reaction study

Variable

TyG Q1

TyG Q2

TyG Q3

TyG Q4

P for interaction

 

Reference

HR(95%CI)

P value

HR(95%CI)

P value

HR(95%CI)

P value

 

Age, year a

       

0.528

 < 55

1

N

 

N

 

N

  

55–64

1

N

 

N

 

N

  

 ≥ 65

1

2.109(0.788–4.624)

0.151

1.279(0.412–2.910)

0.677

2.539(1.227–5.863)

0.017*

 

eGFR, ml/min per 1.73m2 d

       

0.907

eGFR ≥ 90

1

2.040(0.698–4.700)

0.089

1.231(0.902–2.468)

0.932

2.876(1.603–5.886)

0.020*

 

60 ≤ eGFR < 90

1

1.490(0.160–3.724)

0.191

1.476(0.229–2.473)

0.259

1.490(0.162–1.882)

0.819

 

eGFR < 60

1

1.443(0.769–1.994)

0.732

1.102(0.367–1.909)

0.324

1.909(0.947–3.314)

0.635

 

BMI, kg/m2 e

       

0.812

BMI < 18.5 (n = 1117)

1

N

 

N

 

N

  

18.5 ≤ BMI < 24 (n = 18097)

1

0.919(0.828–1.234)

0.527

1.321(0.365–1.098)

0.321

1.102(0.954–1.276)

0.057

 

24 ≤ BMI < 28 (n = 15669)

1

0.533(0.468–2.179)

0.790

0.499(0.281–1.436)

0.129

1.763(0.528–3.110)

0.455

 

BMI ≥ 28 (n = 5791)

1

0.523(0.119–2.176)

0.431

0.153(0.008–2.332)

0.448

2.767(1.023–6.778)

0.023*

 
  1. *Significant data (P < 0.05)
  2. a Age subgroup: adjusted for sex, diabetic family history; history of CVDs; SBP; DBP; BMI; ALT; AST; heart rate; eGFR; HbA1c; smoking habits, drinking habits
  3. b eGFR subgroup: adjusted for age, sex, diabetic family history; history of CVDs; SBP; DBP; BMI; ALT; AST; heart rate; HbA1c; smoking habits, drinking habits
  4. c BMI subgroup: adjusted for age, sex, diabetic family history; history of CVDs; SBP; DBP; eGFR; ALT; AST; heart rate; HbA1c; smoking habits, drinking habits