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Table 2 Hazard ratios(HRs) and 95%Confidence intervals of uACR for CVD events

From: An elevated urinary albumin-to-creatinine ratio increases the risk of incident cardia-cerebrovascular disease in individuals with type 2 diabetes

 

No.

Events

No./1000 person-years

Model 1

Model 2

Model 3

Myocardial infarction

 < 3 mg/mmol

5936

56

2.32

1

1

1

 3-30 mg/mmol

2509

43

4.3

1.86(1.25, 2.76)

1.71(1.15, 2.56)

1.57(1.04, 2.37)

 ≥ 30 mg/mmol

530

19

9.53

4.10(2.44, 6.90)

3.58(2.12, 6.05)

2.86(1.63, 5.00)

 ln(uACR),Per 1 SD

8975

118

3.26

1.64(1.42, 1.90)

1.58(1.34, 1.84)

1.80(1.24, 2.61)

Ischemic stroke

 < 3 mg/mmol

5936

227

9.53

1

1

1

 3-30 mg/mmol

2509

145

14.83

1.55(1.26, 1.91)

1.46(1.19, 1.80)

1.24(1.00, 1.54)

 ≥ 30 mg/mmol

530

64

33.33

3.50(2.65, 4.62)

3.11(2.36, 4.12)

2.46(1.83, 3.30)

 ln(uACR),Per 1 SD

8975

436

12.28

1.49(1.38, 1.62)

1.44(1.33, 1.57)

1.34(1.22, 1.46)

Hemorrhagic stroke

 < 3 mg/mmol

5936

16

0.66

1

1

1

 3-30 mg/mmol

2509

11

1.09

1.66(0.77, 3.58)

1.55(0.72, 3.36)

1.62(0.73, 3.61)

 ≥ 30 mg/mmol

530

6

2.97

4.69(1.84, 11.99)

4.16(1.62, 10.72)

4.69(1.72, 12.78)

 ln(uACR),Per 1 SD

8975

33

0.91

1.51(1.13, 2.01)

1.45(1.08, 1.96)

1.10(0.55, 2.19)

Total CVD events

 3-30 mg/mmol

5936

288

11.87

1

1

1

 3-30 mg/mmol

2509

191

18.97

1.60(1.33, 1.92)

1.45(1.20, 1.74)

1.30(1.07, 1.57)

 ≥ 30 mg/mmol

530

81

40.16

3.57(2.79, 4.572)

2.94(2.29, 3.77)

2.42(1.85, 3.15)

 ln(uACR),Per 1 SD

8975

560

15.41

1.52(1.42, 1.63)

1.44(1.34, 1.55)

1.37(1.26, 1.48)

  1. Model 1: unadjusted;
  2. Model 2: adjusted for age and sex;
  3. Model 3: adjusted for age, gender, SBP, FBG, LDL-cholesterol, BMI, eGFR, smoking, anti-diabetic treatment and antihypertensive treatment