Table 1 Baseline Characteristics Overall and by uACR Categories in Participants

Myocardial infarction, n (%)

118(1.31)

56(0.94)

43(1.71)

19(3.58)

< 0.001

Ischemic stroke, n (%)

436(4.86)

227(3.82)

145(5.78)

64(12.08)

< 0.001

Hemorrhagic stroke, n (%)

33(0.37)

16(0.27)

11(0.44)

6(1.13)

0.006

Total CVD events, n (%)

560(6.24)

288(4.85)

191(7.61)

81(15.28)

< 0.001

Male, n (%)

6475(72.14)

4295(72.36)

1792(71.42)

388(73.21)

0.583

Age, years

61.03 ± 9.98

60.34 ± 9.84

62.08 ± 10.14

63.70 ± 9.98

0.302

uACR*, mg/mmol

1.66

(0.80 4.55)

1.01

(0.63 ~ 1.64)

6.16

(4.13 ~ 11.28)

61.32

(42.46 ~ 111.37)

< 0.001

SBP, mmHg

146.55 ± 20.62

143.49 ± 19.61

151.63 ± 20.88

156.85 ± 22.38

< 0.001

DBP, mmHg

82.83 ± 10.97

81.83 ± 10.40

84.50 ± 11.65

86.12 ± 12.17

< 0.001

Heart rate, bpm

77.453 ± 12.89

76.63 ± 12.55

79.10 ± 13.31

80.09 ± 13.42

0.006

BMI, kg/mm²

25.79 ± 3.44

25.58 ± 3.32

26.14 ± 3.59

26.49 ± 3.724

0.002

Triglycerides *, mmol/L

153

(1.05 ~ 2.32)

1.45

(1.00 ~ 2.18)

1.69

(1.15 ~ 2.63)

1.84

(1.24 ~ 2.80)

0.018

Total cholesterol, mmol/L

5.49 ± 1.18

5.42 ± 1.13

5.59 ± 1.22

5.79 ± 1.41

< 0.001

HDL-C*, mmol/L

1.38

(1.18 ~ 1.62)

1.39(1.19 ~ 1.65)

1.34

(1.16 ~ 1.58)

1.32

(1.12 ~ 1.58)

0.635

LDL-C, mmol/L

3.24 ± 0.95

3.21 ± 0.93

3.30 ± 0.99

3.40 ± 1.07

0.001

FBG, mmol/L

9.10 ± 3.26

8.55 ± 2.94

10.07 ± 3.50

10.76 ± 3.84

< 0.001

HbA1c, %

7.59 ± 1.66

7.32 ± 1.53

8.07 ± 1.75

8.41 ± 1.84

< 0.001

Hemoglobin, g/L

150.49 ± 14.53

150.57 ± 14.11

150.73 ± 14.69

148.35 ± 17.86

< 0.001

hsCRP *

1.10

(0.34 ~ 2.77)

0.92

(0.29 ~ 2.41)

1.43

(0.49 ~ 3.42)

1.77

(0.73 ~ 3.80)

0.566

eGFR, ml/min/1.73m²

82.81 ± 19.61

83.54 ± 18.95

82.69 ± 19.58

75.22 ± 24.77

< 0.001

Smoking, n (%)

3018(33.63)

2026(34.13)

831(33.12)

161(30.38)

0.176

Hypertension, n (%)

5071(56.50)

3057(51.50)

1644(65.52)

370(69.81)

< 0.001

Atrial fibrillation, n (%)

94(1.05)

55(0.93)

33(1.32)

6(1.13)

0.271

Anti-diabetic treatment, n (%)

3749(41.77)

2222(37.43)

1209(48.19)

318(60.00)

< 0.001

 Insulin,

1581(17.62)

877(14.77)

527(21.00)

177(33.40)

< 0.001

 Oral medicine

2173(24.21)

1348(22.71)

683(27.22)

142(26.79)

< 0.001

Antihypertensive treatment, n (%)

3754(41.83)

2382(40.13)

1087(43.32)

285(53.77)

< 0.001