| Overall | Female | Male |
---|---|---|---|
(n = 1715) | (n = 871) | (n = 844) | |
ALT | |||
 Q1 (≤ 15 U/L) | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) |
 Q2 (15–21 U/L) | 1.267 (0.956–1.677) | 1.117 (0.766–1.627) | 1.462 (0.944–2.263) |
 Q3 (21–30 U/L) | 1.505 (1.114–2.032) | 1.239 (0.817–1.879) | 1.839 (1.171–2.888) |
 Q4 (≥ 30 U/L) | 1.790 (1.341–2.388) | 1.659 (1.097–2.508) | 1.877 (1.224–2.877) |
 P for trend | 0.001 | 0.110 | 0.020 |
 Per SD increase | 1.222 (1.098–1.359) | 1.240 (1.067–1.441) | 1.168 (1.004–1.358) |
AST | |||
 Q1 (≤ 16 U/L) | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) |
 Q2 (16–20 U/L) | 1.178 (0.886–1.565) | 1.146 (0.776–1.694) | 1.202 (0.786–1.839) |
 Q3 (20–26 U/L) | 1.233 (0.908–1.676) | 1.210 (0.784–1.868) | 1.225 (0.786–1.911) |
 Q4 (≥ 26 U/L) | 1.667 (1.256–2.213) | 1.464 (0.983–2.180) | 1.800 (1.189–2.723) |
 P for trend | 0.004 | 0.309 | 0.032 |
 Per SD increase | 1.207 (1.085–1.342) | 1.203 (1.037–1.395) | 1.185 (1.012–1.387) |
AST/ALT | |||
 Q1 (≤ 0.78) | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) |
 Q2 (0.78–0.95) | 1.128 (0.843–1.511) | 0.972 (0.614–1.539) | 1.290 (0.881–1.890) |
 Q3 (0.95–1.21) | 0.930 (0.688–1.258) | 0.811 (0.517–1.274) | 1.145 (0.753–1.742) |
 Q4 (≥ 1.21) | 0.647 (0.476–0.878) | 0.679 (0.433–1.064) | 0.608 (0.392–0.944) |
 P for trend | 0.002 | 0.251 | 0.007 |
 Per SD increase | 0.851 (0.763–0.949) | 0.850 (0.730–0.990) | 0.871 (0.748–1.015) |
GGT | |||
 Q1 (≤ 18 U/L) | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) |
 Q2 (18–27 U/L) | 1.541 (1.154–2.057) | 1.546 (1.067–2.239) | 1.497 (0.921–2.433) |
 Q3 (27–46 U/L) | 1.715 (1.262–2.330) | 1.591 (1.040–2.434) | 1.723 (1.062–2.796) |
 Q4 (≥ 46 U/L) | 3.064 (2.239–4.194) | 2.330 (1.489–3.648) | 3.452 (2.129–5.596) |
 P for trend | < 0.001 | 0.002 | < 0.001 |
 Per SD increase | 1.234 (1.093–1.393) | 1.150 (0.989–1.336) | 1.248 (1.048–1.486) |