From: Fasting hepatic insulin clearance reflects postprandial hepatic insulin clearance: a brief report
Parameters | T2DM | Non-DM | ||
---|---|---|---|---|
r-value | P value | r-value | P value | |
Age (years) | 0.27 | 0.07 | -0.19 | N.S. |
Duration of diabetes (years) | 0.05 | N.S. | - | Â |
BMI (kg/m2) | -0.58 | < 0.0005 | -0.15 | N.S. |
Waist circumstance (cm) | -0.55 | < 0.001 | -0.10 | N.S. |
Fasting plasma glucose (mmol/L) | 0.14 | 0.22 | 0.05 | N.S. |
HbA1c (%) | 0.49 | < 0.05 | 0.25 | 0.06 |
AST (IU/L) | -0.27 | 0.06 | 0.18 | N.S. |
ALT (IU/L) | -0.27 | 0.08 | 0.02 | N.S. |
Gamma-GTP (IU/L) | -0.37 | < 0.05 | 0.05 | N.S. |
Fasting insulin (pmol/L) | -0.82 | < 0.0001 | -0.67 | < 0.0001 |
Fasting C-peptide (nmol/L) | -0.42 | < 0.01 | -0.004 | N.S. |
eGFR (mL/min/1.73 m2) | -0.08 | N.S. | 0.13 | N.S. |
Creatinine (mg/dL) | 0.06 | N.S. | -0.15 | N.S. |
HOMA-beta (%) | -0.84 | < 0.0001 | -0.41 | < 0.05 |
HOMA2-beta (%) | -0.77 | < 0.0001 | -0.64 | < 0.0001 |
HOMA-IR | -0.77 | < 0.0001 | -0.62 | < 0.0001 |
HOMA2-IR | -0.80 | < 0.0001 | -0.57 | < 0.0001 |
Sg (min− 1 × 10− 2) | 0.13 | N.S. | 0.01 | N.S |
GDR (mg/kg/min) | 0.38 | < 0.05 | 0.09 | N.S. |
M/I ((100 × mg · kg− 1 · body weight− 1 · min− 1 · mU− 1 · l− 1)) | 0.56 | < 0.0005 | 0.22 | N.S. |
Whole-body insulin clearance (mL/min) | 0.35 | < 0.05 | -0.01 | N.S. |