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Table 4 Odds ratios (95% confidence interval) for severity of hepatic steatosis across non-HDL-C vs. remnant cholesterol concordant/discordant groups by non-HDL-C clinical cut-points and percentile equivalents for remnant cholesterol

From: Remnant cholesterol and severity of nonalcoholic fatty liver disease

 

Crude model

Multivariable model

OR (95% CI)

OR (95% CI)

Mild steatosis

  

 Non-HDL-C < cut-point & RC < cut-point

Reference

Reference

 Non-HDL-C < cut-point & RC ≥ cut-point

2.752 (2.280 to 3.321)***

1.499 (1.193 to 1.883)***

 Non-HDL-C ≥ cut-point & RC < cut-point

1.295 (0.995 to 1.567)

1.314 (0.992 to 3.095)

 Non-HDL-C ≥ cut-point & RC ≥ cut-point

3.282 (2.877 to 3.744)***

2.003 (1.615 to 2.484)***

Moderate-to-severe steatosis

  

 Non-HDL-C < cut-point & RC < cut-point

Reference

Reference

 Non-HDL-C < cut-point & RC ≥ cut-point

3.998 (2.669 to 5.990)***

1.844 (1.099 to 3.095)*

 Non-HDL-C ≥ cut-point & RC < cut-point

0.783 (0.437 to 1.400)

1.645 (0.792 to 3.414)

Non-HDL-C ≥ cut-point & RC ≥ cut-point

5.347 (3.931 to 7.272)***

3.365 (2.025 to 5.594)***

  1. The clinical cutoffoff points for non-HDL-C and remnant cholesterol were 3.37 mmol/L and 0.70 mmol/L, respectively
  2. The multivariable model was adjusted for age, sex, BMI, systolic blood pressure, diastolic blood pressure, smoking, fasting plasma glucose, glycated hemoglobin A1c, γ-glutamyl transpeptidase, low-density lipoprotein-cholesterol and total cholesterol
  3. * P < 0.05, ** P < 0.005, *** P < 0.001
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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