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Table 3 Odds ratios (95% confidence interval) for NAFLD severity across LDL-C vs. remnant cholesterol concordant/discordant groups by LDL-C clinical cut-points and percentile equivalents for remnant cholesterol

From: Remnant cholesterol and severity of nonalcoholic fatty liver disease

 

Crude model

Multivariable model

OR (95% CI)

OR (95% CI)

Mild steatosis

  

 LDL-C < cut-point & RC < cut-point

Reference

Reference

 LDL-C < cut-point & RC ≥ cut-point

3.373 (2.841 to 4.005)***

1.770 (1.425 to 2.199)***

 LDL-C ≥ cut-point & RC < cut-point

1.060 (0.888 to 1.266)

1.059 (0.882 to 1.364)

 LDL-C ≥ cut-point & RC ≥ cut-point

2.858 (2.477 to 3.298)***

1.609 (1.252 to 2.067)***

Moderate-to-severe steatosis

  

 LDL-C < cut-point & RC < cut-point

Reference

Reference

 LDL-C < cut-point & RC ≥ cut-point

5.874 (4.126 to 8.362)***

2.576 (1.596 to 4.160)***

 LDL-C ≥ cut-point & RC < cut-point

0.554 (0.324 to 1.289)

0.913 (0.451 to 1.849)

 LDL-C ≥ cut-point & RC ≥ cut-point

3.763 (2.712 to 5.221)***

1.842 (1.033 to 3.287)*

  1. The clinical cutoffoff points for LDL-C and remnant cholesterol were 2.59 mmol/L and 0.70 mmol/L, respectively
  2. The multivariable model was adjusted for age, sex, BMI, systolic blood pressure, diastolic blood pressure, smoking, fasting plasma glucose, glycated hemoglobin A1c, γ-glutamyl transpeptidase, low-density lipoprotein-cholesterol and total cholesterol
  3. * P < 0.05, ** P < 0.005, *** P < 0.001
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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