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Table 1 Clinical characteristics of participants stratified by quartiles of remnant cholesterol

From: Remnant cholesterol and severity of nonalcoholic fatty liver disease

Variables

Quartile 1

(n = 1,536)

Quartile 2

(n = 1,540)

Quartile 3

(n = 1,479)

Quartile 4

(n = 1,498)

P value

Female, %

56.38

46.04 *

36.58 † §

28.50 ‡ || ¶

< 0.001

Age, year

49.69 (12.51)

50.96 (11.31) *

51.53 (10.42) † §

52.07 (10.02) ‡ || ¶

< 0.001

Body mass index, kg/m2

22.64 (2.94)

23.73 (3.01) *

24.56 (2.97) † §

25.55 (3.01) ‡ || ¶

< 0.001

Current smoker, %

13.48

16.88 *

24.75 † §

30.77 ‡ || ¶

< 0.001

Systolic blood pressure, mmHg

117.93 (16.83)

122.62 (17.29) *

123.92 (16.79) † §

126.11 (16.08) ‡ || ¶

< 0.001

Diastolic blood pressure, mmHg

69.55 (11.13)

72.95 (11.11) *

73.95 (11.03) † §

75.98 (10.72) ‡ || ¶

< 0.001

Serum uric acid, µmol/L

289.03 (71.58)

318.65 (80.43) *

339.63 (82.40) † §

367.94 (83.28) ‡ || ¶

< 0.001

Total cholesterol, mmol/L

4.29 (0.77)

4.66 (0.76) *

5.00 (0.84) † §

5.41 (0.97) ‡ || ¶

< 0.001

Triglyceride, mmol/L

0.83 (0.25)

1.16 (0.33) *

1.56 (0.43) † §

2.88 (1.86) ‡ || ¶

< 0.001

HDL-C, mmol/L

1.51 (0.36)

1.33 (0.32) *

1.20 (0.28) † §

1.03 (0.24) ‡ || ¶

< 0.001

LDL-C, mmol/L

2.36 (0.62)

2.68 (0.62) *

2.95 (0.71) † §

3.00 (0.87) ‡ || ¶

< 0.001

Fasting plasma glucose, mmol/L

4.75 (0.83)

4.92 (1.03) *

5.00 (1.18) † §

5.23 (1.56) ‡ || ¶

< 0.001

Glycated hemoglobin A1c, %

5.64 (0.59)

5.74 (0.74) *

5.82 (0.76) † §

5.97 (1.03) ‡ || ¶

< 0.001

Remnant cholesterol, mmol/L

0.43 (0.10)

0.65 (0.05) *

0.85 (0.07) † §

1.37 (0.56) ‡ || ¶

< 0.001

γ-glutamyl transpeptidase, U/L

15.00 [12.00, 22.00]

19.00 [14.00, 28.00] *

24.00 [16.00, 36.00] † §

32.00 [21.00, 51.00] ‡ || ¶

< 0.001

Severity of hepatic steatosis, %

    

< 0.001

 Mild steatosis

21.29

32.14 *

40.50 † §

54.14 ‡ || ¶

 

 Moderate-to-severe steatosis

1.89

3.64 *

6.42 † §

11.68 ‡ || ¶

 

 Overall steatosis

23.18

35.78 *

46.92 † §

65.82 ‡ || ¶

 
  1. Data are presented as the mean (standard deviation), median (interquartile range) or as proportions
  2. HDL-C, high density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol
  3. P value: statistical significance among the four groups; * Statistical significance with Bonferroni correction for measurement data between Quartile 1 and Quartile 2, † Quartile 1 versus Quartile 3, ‡ Quartile 1 versus Quartile 4, § Quartile 2 versus Quartile 3, || Quartile 2 versus Quartile 4, |¶ Quartile 3 versus Quartile 4