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Table 3 Association of LEP G2548A (rs7799039) with indicators of MetS

From: LEP (G2548A-G19A) and ADIPOQ (T45G-G276T) gene polymorphisms are associated with markers for metabolic syndrome

Indicator

Inheritance model

Recessive

 

Overdominant

 

GG-GA

AA

 

GG-AA

GA

 

OR (95% CI)1

p

OR (95% CI)1

p

Dyslipidemia

0.74 (0.32–1.71)

7.97 (2.17–29.36)

0.008

2.53 (0.85–7.46)

0.56 (0.22–1.43)

0.190

TG > 150 mg/dL

1.47 (0.74–2.94)

1.26 (0.37–4.26)

0.077

0.64 (0.25–1.62)

0.58 (0.26–1.31)

0.100

FBG > 100 mg/dL

1.36 (0.67–2.78)

1.78 (0.47–6.73)

0.420

0.93 (0.35–2.48)

0.59 (0.25–1.39)

0.480

Diabetes mellitus

0.37 (0.10–1.30)

3.41 (0.32–35.75)

0.230

1.15 (0.27–4.86)

0.09 (0.02–0.53)

0.085

Low HDL

1.53 (0.72–3.26)

7.01 (1.65–29.71)

0.320

2.41 (0.80–7.26)

0.76 (0.32–1.82)

0.640

Hypertension

1.24 (0.42–3.63)

13.02 (1.76–96.44)

0.120

3.03 (0.76–12.02)

0.63 (0.17–2.34)

0.340

Obesity

1.03 (0.50.2.13)

1.67 (0.64–4.38)

0.260

0.45 (0.18–1.13)

0.31 (0.12–0.77)

0.061

  1. 1Multiple logistic regression analysis was performed with adjustment for age, sex, and waist circumference