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Table 3 Cox proportional hazard regression model for CKD incidence of two different insulin resistance indices

From: Comparison of METS-IR and HOMA-IR for predicting new-onset CKD in middle-aged and older adults

 

CKD Incidence

HR

95% CI

P-value

METS-IR (per 1 increment)

 Unadjusted

1.04

1.03–1.04

 < 0.001

 Model 1

1.06

1.05–1.08

 < 0.001

 Model 2

1.06

1.03–1.07

 < 0.001

HOMA-IR (per 1 increment)

 Unadjusted

1.12

1.08–1.15

 < 0.001

 Model 1

1.06

1.03–1.10

 < 0.001

 Model 2

1.04

1.00–1.08

0.031

  1. METS-IR metabolic score for insulin resistance, HOMR-IR homeostatic model assessment for insulin resistance, CKD chronic kidney disease, HR hazard ratio, CI confidence intervals, BMI body mass index, HTN hypertension, DM diabetes mellitus, CRP C-reactive protein
  2. Model 1: Adjusted for age, sex, BMI, physical activity, smoking, and alcohol drinking
  3. Model 2: Model 1, HTN, DM, dyslipidemia, and CRP