| Â | Model 1 | Model 2 | Model 3 | Model 4 |
|---|
| Â | R | P | R | P | R | P | R | P |
MoCA | -0.156 | 0.206 | -0.183 | 0.152 | -0.165 | 0.199 | -0.004 | 0.975 |
DST | -0.138 | 0.267 | -0.177 | 0.165 | -0.174 | 0.175 | -0.095 | 0.437 |
VFT | -0.183 | 0.139 | -0.189 | 0.137 | -0.176 | 0.172 | -0.108 | 0.414 |
CDT | -0.167 | 0.176 | 0.154 | 0.228 | -0.193 | 0.133 | -0.084 | 0.528 |
TMTA | 0.334 | 0.005** | -0.355 | 0.004** | 0.342 | 0.007** | 0.279 | 0.032* |
TMTB | 0.354 | 0.003** | 0.371 | 0.003** | 0.363 | 0.004** | 0.348 | 0.007** |
AVLT-IR | -0.192 | 0.120 | -0.225 | 0.076 | -0.231 | 0.071 | -0.182 | 0.167 |
AVLT-DR | -0.236 | 0.055 | -0.253 | 0.046* | -0.263 | 0.039* | -0.204 | 0.122 |
LMT | -0.126 | 0.310 | -0.088 | 0.495 | -0.115 | 0.372 | -0.054 | 0.684 |
- Notes: Model 1 showed the Pearson association between HOMA-IR and cognitive function in pa-tients with T2DM; Model 2 showed the partial correlation between HOMA-IR and cognitive function adjusting for age, gender, duration of DM and hypertension; Model 3 showed the partial correlation between HOMA-IR and cognitive function adjusting for age, gender, duration of DM and hypertension as well as HbA1c; Model 4 showed the partial correlation between HOMA-IR and cognitive function adjusting for age, gender, duration of DM and hypertension, HbA1c, BMI, TG, and HDL-C. * P < 0.05; ** P < 0.01. Abbreviations: T2DM, type 2 diabetes mellitus; NAFLD, non-alcoholic fatty liver disease; MoCA, Montreal cognitive assessment; DST, digit span test; VFT, verbal fluency test; CDT, clock drawing test; TMTA, trail making test-A; TMTB, trail making test-B; AVLT-IR, au-ditory verbal learning test-immediate recall; AVLT-DR, auditory verbal learning test-delayed recall; LMT, logical memory test; DM, diabetes mellitus; HbA1c, glycosylated hemoglobin; BMI, body mass index; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol
