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Table 1 Comparation of clinical parameters and neurophysiological test results between Non-MCI group and MCI group

From: Impact of insulin resistance on mild cognitive impairment in type 2 diabetes mellitus patients with non-alcoholic fatty liver disease

 

Non-MCI group (n = 85)

MCI group (n = 58)

P

Age (years)

60.00 (55.00-73.50)

59.00 (54.00-66.35)

0.818b

Female (n, %)

40, 40.06

22, 37.93

0.279c

BMI (kg/m2)

24.41 (22.58–25.71)

24.77 (22.38–27.12)

0.706b

Duration of DM (years)

10.00 (6.50–18.00)

10.00 (7.00-15.50)

0.208b

Duration of HBP (years)

0.00 (0.00–10.00)

0.00 (0.00-5.25)

0.875b

Systolic pressure (mmHg)

131.01 ± 16.96

135.07 ± 20.42

0.141a

Diastolic pressure (mmHg)

78.49 ± 9.95

81.90 ± 11.54

0.062a

FPG (mmol/l)

6.80 (5.51–8.34)

8.18 (6.21–10.05)

0.109b

HbA1c (%)

7.90 (6.90–9.15)

8.80 (6.88–9.73)

0.031b*

HOMA-IR

2.38 (2.16–2.90)

2.74 (2.22–3.21)

0.009b

TG (mmol/l)

1.41 (0.92–1.97)

1.70 (0.97–2.50)

0.207b

TC (mmol/l)

4.32 ± 0.98

4.45 ± 1.37

0.554a

HDL-C (mmol/l)

1.09 ± 0.31

1.04 ± 0.30

0.395a

LDL-C (mmol/l)

2.52 ± 0.78

2.57 ± 1.00

0.759a

NAFLD (n, %)

33, 38.82

34, 58.62

0.020c*

MoCA

29.00 (28.00–30.00)

24.00 (24.00–25.00)

< 0.001b*

DST

12.00 (10.00–13.00)

10.00 (9.00–12.00)

0.032 b*

VFT

17.00 (14.00-21.50)

13.00 (9.00–17.00)

< 0.001b*

CDT

4.00 (3.00–4.00)

3.00 (2.00–3.00)

< 0.001b*

TMTA

60.14 ± 16.06

67.50 ± 20.38

0.017a*

TMTB

125.00 (100.00-182.00)

176.50 (128.50-219.75)

0.003 b*

AVLT-IR

18.72 ± 4.80

16.29 ± 4.49

0.003a*

AVLT-DR

6.00 (5.00–8.00)

5.00 (4.00-6.25)

0.028b*

LMT

11.00 (7.00–14.00)

8.00 (6.00–10.00)

0.004b*

  1. Notes: a Student’s t test was employed for normally distributed variables; b The Mann-Whitney U test was employed for asymmetrically distributed variables; c The Chi-square test was employed for categorical variables. * P < 0.05; ** P < 0.01. Abbreviations: MCI, mild cognitive impairment; BMI, body mass index; DM, diabetes mellitus; HBP, high blood pressure; FPG, fasting plasma glucose; HbA1c, glycosylated hemoglobin; TG, triglyceride; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; NAFLD, non-alcoholic fatty liver disease; MoCA, Montreal cognitive assessment; DST, digit span test; VFT, verbal fluency test; CDT, clock drawing test; TMTA, trail making test-A; TMTB, trail making test-B; AVLT-IR, auditory verbal learning test-immediate recall; AVLT-DR, auditory verbal learning test-delayed recall; LMT, logical memory test