Cost-effectiveness of continuous glucose monitoring with FreeStyle Libre® in Brazilian insulin-treated patients with types 1 and 2 diabetes mellitus

Table 4 Utility data inputs

Parameter	Mean	Lower bound	Upper bound	Source
Utility related to FSL utilization	0.030	0.024	0.036	Matza et al. [31]
T1DM
T1DM utility	0.801	0.787	1	Bahia et al. [29]
Disutility of non-severe hypoglycemia events	0.131	0.129	0.133	Lamounier et al. [7] and Laurisden et al. [30]
Disutility of severe daytime hypoglycemic events	0.047	0.033	0.062	Evans et al. [32]
Disutility of severe nocturnal hypoglycemic events	0.051	0.037	0.065	Evans et al. [32]
Disutility of diabetic ketoacidosis events	0.0091	0	0.0287	Peasgood et al. [33]
T2DM
T2DM utility	0.801	0.787	1	Bahia et al. [29]
Disutility of non-severe hypoglycemia events	0.079	0.077	0.082	Lamounier et al. [7] and Laurisden et al. [30]
Disutility of severe daytime hypoglycemic events	0.047	0.033	0.062	Evans et al. [32]
Disutility of severe nocturnal hypoglycemic events	0.051	0.037	0.065	Evans et al. [32]
Disutility of diabetic ketoacidosis events	0.0091	0	0.0287	Peasgood et al. [33]

Mean numbers were used in base-case analysis. Lower and upper bound values were used in sensitivity analysis
T1DM, Type 1 diabetes mellitus; T2DM, type 2 diabetes mellitus

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