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Table 3 The association of TyG index with CMM in different blood pressure status

From: Relationship of triglyceride-glucose index with cardiometabolic multi-morbidity in China: evidence from a national survey

TyG index

Total N

No. of events

(Incident rate#)

Model 1

 

Model 2

 

Model 3

 

 HR (95% CI)

P value

HR (95% CI)

P value

HR (95% CI)

P value

Normotension

        

TyG index$

2367

82 (4.99)

1.67 (1.23–2.25)

0.001

1.46 (1.05–2.04)

0.027

1.47 (0.93–2.30)

0.098

Q1 (≤ 8.22)

765

16 (3.00)

Ref.

 

Ref.

 

Ref.

 

Q2 (> 8.22 to 8.59)

661

22 (4.80)

1.61 (0.85–3.07)

0.146

1.45 (0.76–2.78)

0.260

1.49 (0.77–2.87)

0.237

Q3 (> 8.59 to 9.03)

532

22 (5.96)

1.95 (1.02–3.71)

0.042

1.57 (0.82–3.03)

0.176

1.66 (0.85–3.22)

0.138

Q4 (> 9.03)

409

22 (7.78)

2.58 (1.36–4.92)

0.004

1.87 (0.96–3.68)

0.067

1.61 (0.84–3.70)

0.135

Prehypertension

        

TyG index$

1865

105 (8.14)

2.06 (1.61–2.64)

< 0.001

1.82 (1.39–2.39)

< 0.001

1.91 (1.26–2.90)

0.002

Q1 (≤ 8.22)

477

9 (2.71)

Ref.

 

Ref.

 

Ref.

 

Q2 (> 8.22 to 8.59)

465

20 (6.20)

2.31 (1.05–5.07)

0.037

2.02 (0.91–4.45)

0.083

1.79 (0.78–4.16)

0.170

Q3 (> 8.59 to 9.03)

479

35 (10.56)

3.97 (1.91–8.25)

< 0.001

3.21 (1.53–6.74)

0.002

1.66 (1.15–5.73)

0.021

Q4 (> 9.03)

444

41 (13.44)

5.00 (2.43–10.29)

< 0.001

3.61 (1.72–7.55)

0.001

2.47 (1.08–5.66)

0.033

Hypertension

        

TyG index$

3738

451 (17.68)

1.51 (1.35–1.70)

< 0.001

1.38 (1.20–1.59)

< 0.001

1.37 (1.10–1.71)

0.005

Q1 (≤ 8.22)

750

59 (11.50)

Ref.

 

Ref.

 

Ref.

 

Q2 (> 8.22 to 8.59)

867

80 (13.46)

1.12 (0.80–1.57)

0.509

1.15 (0.79–1.67)

0.479

0.83 (0.57–1.23)

0.352

Q3 (> 8.59 to 9.03)

982

118 (17.56)

1.48 (1.08–2.02)

0.014

1.17 (0.82–1.68)

0.394

0.89 (0.65–1.24)

0.494

Q4 (> 9.03)

1139

194 (25.15)

2.15 (1.61–2.88)

< 0.001

1.59 (1.13–2.24)

0.009

0.91 (0.68–1.21)

0.499

  1. Model 1: unadjusted
  2. Model 2: adjusted for age, sex, SBP, DBP, BMI, alcohol consumption and smoking status
  3. Model 3: model 2 + further adjusted for marital status, education, rural residence, heart rate, BUN, serum creatinine, UA, hemoglobin, TC, LDL, stroke, heart disease, and DM
  4. BMI, body mass index; BUN, blood urea nitrogen; CI, confidence interval; CMM, cardiometabolic multimorbidity; DBP, diastolic blood pressure; DM, diabetes mellitus; HR, hazard ratio; LDL, low density lipoprotein; Q, quartile; Ref, reference; SBP, systolic blood pressure; TC, total cholesterol; UA, uric acid
  5. #Incident rate was presented as per 1000 person-years of follow-up
  6. $Per 1.0 increase
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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