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Table 2 comparison of diabetes genetic risk scores according to diabetes control as defined by HbA1c levels, by survey period, CoLaus study, Lausanne, Switzerland

From: Genetic risk scores: are they important for diabetes management? results from multiple cross-sectional studies

Ā 

Bivariate

Ā 

Multivariable

Period/Score

Not controlled

Controlled

P-value

Not controlled

Controlled

P-value

Second follow-up (N)

132

92

Ā 

132

92

Ā 

Andersson

40.0ā€‰Ā±ā€‰4.6

40.7ā€‰Ā±ā€‰5.1

0.291

40.0ā€‰Ā±ā€‰0.4

40.6ā€‰Ā±ā€‰0.5

0.423

Martono

62.1ā€‰Ā±ā€‰4.7

61.0ā€‰Ā±ā€‰4.5

0.085

62.2ā€‰Ā±ā€‰0.4

61.1ā€‰Ā±ā€‰0.5

0.105

Szcerbinski

0.53ā€‰Ā±ā€‰0.41

0.50ā€‰Ā±ā€‰0.37

0.585

0.54ā€‰Ā±ā€‰0.04

0.50ā€‰Ā±ā€‰0.05

0.524

Werissa

17.5ā€‰Ā±ā€‰3.3

17.5ā€‰Ā±ā€‰3.1

0.992

17.6ā€‰Ā±ā€‰0.3

17.5ā€‰Ā±ā€‰0.4

0.759

Liu

2.88ā€‰Ā±ā€‰0.34

2.80ā€‰Ā±ā€‰0.32

0.100

2.89ā€‰Ā±ā€‰0.03

2.80ā€‰Ā±ā€‰0.04

0.067

Pechlivanis

109ā€‰Ā±ā€‰6

107ā€‰Ā±ā€‰6

0.069

109ā€‰Ā±ā€‰1

107ā€‰Ā±ā€‰1

0.129

Wang

1.49ā€‰Ā±ā€‰0.38

1.47ā€‰Ā±ā€‰0.38

0.748

1.50ā€‰Ā±ā€‰0.03

1.47ā€‰Ā±ā€‰0.04

0.542

Large score

126ā€‰Ā±ā€‰9

128ā€‰Ā±ā€‰11

0.134

126ā€‰Ā±ā€‰1

128ā€‰Ā±ā€‰1

0.070

Short score

9.8ā€‰Ā±ā€‰2.2

9.8ā€‰Ā±ā€‰2.4

0.986

9.8ā€‰Ā±ā€‰0.2

9.7ā€‰Ā±ā€‰0.3

0.840

Third follow-up (N)

95

62

Ā 

95

62

Ā 

Andersson

39.2ā€‰Ā±ā€‰4.5

41.1ā€‰Ā±ā€‰4.8

0.011

39.2ā€‰Ā±ā€‰0.5

41.0ā€‰Ā±ā€‰0.6

0.023

Martono

61.8ā€‰Ā±ā€‰4.8

62.2ā€‰Ā±ā€‰5.3

0.579

61.7ā€‰Ā±ā€‰0.5

62.3ā€‰Ā±ā€‰0.6

0.509

Szcerbinski

0.48ā€‰Ā±ā€‰0.43

0.58ā€‰Ā±ā€‰0.42

0.154

0.48ā€‰Ā±ā€‰0.04

0.58ā€‰Ā±ā€‰0.05

0.149

Werissa

17.1ā€‰Ā±ā€‰3.6

17.9ā€‰Ā±ā€‰3.1

0.189

17.1ā€‰Ā±ā€‰0.3

17.9ā€‰Ā±ā€‰0.4

0.188

Liu

2.83ā€‰Ā±ā€‰0.37

2.86ā€‰Ā±ā€‰0.33

0.669

2.83ā€‰Ā±ā€‰0.04

2.86ā€‰Ā±ā€‰0.05

0.671

Pechlivanis

109ā€‰Ā±ā€‰6

109ā€‰Ā±ā€‰7

0.880

109ā€‰Ā±ā€‰1

109ā€‰Ā±ā€‰1

0.582

Wang

1.52ā€‰Ā±ā€‰0.42

1.43ā€‰Ā±ā€‰0.34

0.175

1.52ā€‰Ā±ā€‰0.04

1.43ā€‰Ā±ā€‰0.05

0.172

Large score

125ā€‰Ā±ā€‰10

127ā€‰Ā±ā€‰10

0.250

125ā€‰Ā±ā€‰1

127ā€‰Ā±ā€‰1

0.351

Short score

9.4ā€‰Ā±ā€‰2.2

10.0ā€‰Ā±ā€‰2.4

0.114

9.4ā€‰Ā±ā€‰0.2

10.0ā€‰Ā±ā€‰0.3

0.123

  1. Results are expressed as averageā€‰Ā±ā€‰standard deviation for the bivariate analyses and as multivariate adjusted meanā€‰Ā±ā€‰standard error for multivariate analyses. Between-group comparisons performed using student t-test for bivariate analyses and ANCOVA adjusting for age (continuous), gender, marital status (yes, no), educational level (high, medium, low), smoking categories (never, former, current), alcohol consumption (yes, no) and body mass index categories (normal, overweight, obese)