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Table 1 comparison of diabetes genetic risk scores according to diabetes control as defined by glucose levels, by survey period, CoLaus study, Lausanne, Switzerland

From: Genetic risk scores: are they important for diabetes management? results from multiple cross-sectional studies

Ā 

Bivariate

Ā 

Multivariable

Period/Score

Not controlled

Controlled

P-value

Not controlled

Controlled

P-value

Baseline (N)

150

79

Ā 

150

79

Ā 

Ā Andersson

41.2ā€‰Ā±ā€‰5.2

40.7ā€‰Ā±ā€‰4.7

0.499

41.2ā€‰Ā±ā€‰0.4

40.6ā€‰Ā±ā€‰0.6

0.356

Ā Martono

62.1ā€‰Ā±ā€‰4.5

61.6ā€‰Ā±ā€‰4.7

0.377

62.1ā€‰Ā±ā€‰0.4

61.6ā€‰Ā±ā€‰0.5

0.447

Ā Szcerbinski

0.53ā€‰Ā±ā€‰0.44

0.53ā€‰Ā±ā€‰0.41

0.944

0.52ā€‰Ā±ā€‰0.04

0.54ā€‰Ā±ā€‰0.05

0.833

Ā Werissa

17.5ā€‰Ā±ā€‰3.4

17.7ā€‰Ā±ā€‰3.3

0.555

17.5ā€‰Ā±ā€‰0.3

17.8ā€‰Ā±ā€‰0.4

0.534

Ā Liu

2.86ā€‰Ā±ā€‰0.32

2.91ā€‰Ā±ā€‰0.30

0.274

2.86ā€‰Ā±ā€‰0.03

2.91ā€‰Ā±ā€‰0.04

0.251

Ā Pechlivanis

108ā€‰Ā±ā€‰6

109ā€‰Ā±ā€‰6

0.825

108ā€‰Ā±ā€‰1

108ā€‰Ā±ā€‰1

0.938

Ā Wang

1.52ā€‰Ā±ā€‰0.38

1.55ā€‰Ā±ā€‰0.38

0.571

1.52ā€‰Ā±ā€‰0.03

1.55ā€‰Ā±ā€‰0.04

0.632

Ā Large score

130ā€‰Ā±ā€‰10

128ā€‰Ā±ā€‰10

0.327

130ā€‰Ā±ā€‰1

128ā€‰Ā±ā€‰1

0.339

Ā Short score

10.1ā€‰Ā±ā€‰2.4

10.0ā€‰Ā±ā€‰2.4

0.810

10.1ā€‰Ā±ā€‰0.2

9.9ā€‰Ā±ā€‰0.3

0.574

First follow-up (N)

153

83

Ā 

153

83

Ā 

Ā Andersson

40.1ā€‰Ā±ā€‰4.7

40.7ā€‰Ā±ā€‰5.3

0.362

40.2ā€‰Ā±ā€‰0.4

40.5ā€‰Ā±ā€‰0.5

0.633

Ā Martono

62.6ā€‰Ā±ā€‰4.2

61.5ā€‰Ā±ā€‰4.6

0.082

62.6ā€‰Ā±ā€‰0.3

61.5ā€‰Ā±ā€‰0.5

0.087

Ā Szcerbinski

0.56ā€‰Ā±ā€‰0.41

0.49ā€‰Ā±ā€‰0.40

0.221

0.56ā€‰Ā±ā€‰0.03

0.49ā€‰Ā±ā€‰0.04

0.233

Ā Werissa

17.5ā€‰Ā±ā€‰3.3

17.1ā€‰Ā±ā€‰2.9

0.356

17.6ā€‰Ā±ā€‰0.3

17.1ā€‰Ā±ā€‰0.3

0.309

Ā Liu

2.89ā€‰Ā±ā€‰0.33

2.85ā€‰Ā±ā€‰0.35

0.331

2.89ā€‰Ā±ā€‰0.03

2.85ā€‰Ā±ā€‰0.04

0.411

Ā Pechlivanis

109ā€‰Ā±ā€‰6

107ā€‰Ā±ā€‰7

0.093

108ā€‰Ā±ā€‰1

107ā€‰Ā±ā€‰1

0.109

Ā Wang

1.54ā€‰Ā±ā€‰0.39

1.54ā€‰Ā±ā€‰0.38

0.877

1.54ā€‰Ā±ā€‰0.03

1.54ā€‰Ā±ā€‰0.04

0.946

Ā Large score

127ā€‰Ā±ā€‰10

128ā€‰Ā±ā€‰11

0.392

127ā€‰Ā±ā€‰1

128ā€‰Ā±ā€‰1

0.768

Ā Short score

9.8ā€‰Ā±ā€‰2.3

9.9ā€‰Ā±ā€‰2.4

0.873

9.8ā€‰Ā±ā€‰0.2

9.8ā€‰Ā±ā€‰0.3

0.833

Second follow-up (N)

110

114

Ā 

110

114

Ā 

Ā Andersson

40.3ā€‰Ā±ā€‰4.6

40.2ā€‰Ā±ā€‰5.0

0.933

40.3ā€‰Ā±ā€‰0.5

40.2ā€‰Ā±ā€‰0.5

0.913

Ā Martono

61.9ā€‰Ā±ā€‰4.7

61.4ā€‰Ā±ā€‰4.5

0.382

62.0ā€‰Ā±ā€‰0.5

61.5ā€‰Ā±ā€‰0.5

0.492

Ā Szcerbinski

0.54ā€‰Ā±ā€‰0.40

0.49ā€‰Ā±ā€‰0.39

0.338

0.56ā€‰Ā±ā€‰0.04

0.49ā€‰Ā±ā€‰0.04

0.207

Ā Werissa

17.6ā€‰Ā±ā€‰3.4

17.4ā€‰Ā±ā€‰3.0

0.678

17.8ā€‰Ā±ā€‰0.3

17.4ā€‰Ā±ā€‰0.3

0.447

Ā Liu

2.88ā€‰Ā±ā€‰0.36

2.82ā€‰Ā±ā€‰0.30

0.209

2.89ā€‰Ā±ā€‰0.03

2.82ā€‰Ā±ā€‰0.03

0.166

Ā Pechlivanis

109ā€‰Ā±ā€‰6

107ā€‰Ā±ā€‰6

0.034

109ā€‰Ā±ā€‰1

108ā€‰Ā±ā€‰1

0.064

Ā Wang

1.49ā€‰Ā±ā€‰0.40

1.47ā€‰Ā±ā€‰0.37

0.720

1.51ā€‰Ā±ā€‰0.04

1.47ā€‰Ā±ā€‰0.04

0.473

Ā Large score

127ā€‰Ā±ā€‰10

127ā€‰Ā±ā€‰11

0.494

126ā€‰Ā±ā€‰1

127ā€‰Ā±ā€‰1

0.420

Ā Short score

9.8ā€‰Ā±ā€‰2.2

9.8ā€‰Ā±ā€‰2.4

0.866

9.8ā€‰Ā±ā€‰0.2

9.7ā€‰Ā±ā€‰0.2

0.906

Third follow-up (N)

92

65

Ā 

92

65

Ā 

Ā Andersson

39.7ā€‰Ā±ā€‰5.2

40.2ā€‰Ā±ā€‰4.0

0.518

39.9ā€‰Ā±ā€‰0.5

40.0ā€‰Ā±ā€‰0.6

0.857

Ā Martono

61.8ā€‰Ā±ā€‰4.9

62.2ā€‰Ā±ā€‰5.0

0.578

61.8ā€‰Ā±ā€‰0.5

62.2ā€‰Ā±ā€‰0.6

0.586

Ā Szcerbinski

0.53ā€‰Ā±ā€‰0.46

0.50ā€‰Ā±ā€‰0.39

0.586

0.55ā€‰Ā±ā€‰0.04

0.48ā€‰Ā±ā€‰0.05

0.320

Ā Werissa

17.3ā€‰Ā±ā€‰3.7

17.6ā€‰Ā±ā€‰3.1

0.559

17.3ā€‰Ā±ā€‰0.4

17.5ā€‰Ā±ā€‰0.4

0.714

Ā Liu

2.85ā€‰Ā±ā€‰0.39

2.83ā€‰Ā±ā€‰0.31

0.622

2.87ā€‰Ā±ā€‰0.04

2.81ā€‰Ā±ā€‰0.04

0.339

Ā Pechlivanis

108ā€‰Ā±ā€‰6

110ā€‰Ā±ā€‰7

0.094

108ā€‰Ā±ā€‰1

110ā€‰Ā±ā€‰1

0.079

Ā Wang

1.51ā€‰Ā±ā€‰0.41

1.45ā€‰Ā±ā€‰0.36

0.328

1.52ā€‰Ā±ā€‰0.04

1.44ā€‰Ā±ā€‰0.05

0.255

Ā Large score

126ā€‰Ā±ā€‰10

126ā€‰Ā±ā€‰9

0.742

126ā€‰Ā±ā€‰1

126ā€‰Ā±ā€‰1

0.892

Ā Short score

9.8ā€‰Ā±ā€‰2.4

9.5ā€‰Ā±ā€‰2.1

0.519

9.8ā€‰Ā±ā€‰0.2

9.5ā€‰Ā±ā€‰0.3

0.352

  1. Results are expressed as averageā€‰Ā±ā€‰standard deviation for the bivariate analyses and as multivariate adjusted meanā€‰Ā±ā€‰standard error for multivariate analyses. Between-group comparisons performed using student t-test for bivariate analyses and ANCOVA adjusting for age (continuous), gender, marital status (yes, no), educational level (high, medium, low), smoking categories (never, former, current), alcohol consumption (yes, no) and body mass index categories (normal, overweight, obese)