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Table 1 Clinical characteristics of patients with T2DM according to infectious disease status

From: The association between plasma free amino acids and type 2 diabetes mellitus complicated with infection in Chinese patients

Variables

The group with infection in T2DM (n = 109)

Mean/number

(SD or %)

The group without infection in T2DM (n = 923)

Mean/number

(SD or %)

P

N

109(10.6)

923(89.4)

 

Age, years

62.61 ± 14.02

56.60 ± 13.66

< 0.0001*

Duration of diabetes, years

7.00(1.00, 10.50)

5.00(0.00, 10.00)

0.140***

Male Gender

45(41.3)

504(54.6)

0.008**

BMI, kg/m2

19.16 ± 1.46

26.02 ± 3.37

< 0.0001*

BMI categories

  

< 0.0001**

< 24

109(100)

272(29.5)

 

24 ≥ and < 28

0(0)

430(46.6)

 

≥ 28

0(0)

221(23.9)

 

Height, cm

164.97 ± 8.11

166.65 ± 8.18

0.042*

Weight, kg

67.82 ± 13.51

70.64 ± 13.10

0.034*

SBP, mmHg

140.64 ± 28.18

140.38 ± 23.46

0.916*

DBP, mmHg

82.00 ± 15.69

82.51 ± 13.25

0.710*

Smoking

24(22.0)

307(33.3)

0.017**

Drinking

22(20.2)

268(29.0)

0.052**

HbA1c, %(mmol/mol)

9.75 ± 2.07(83 ± 22)

9.58 ± 1.83(81 ± 20)

0.389*

HbA1c categories

  

0.243**

< 7%(53mmol/mol)

6(5.5)

71(7.7)

 

7%~8%(53 ~ 64mmol/mol)

17(94.5)

89(92.3)

 

≥ 8%(64mmol/mol)

46(42.2)

402(43.6)

 

TG, mmol/L

1.98 ± 1.20

2.06 ± 1.35

0.548*

TG categories

  

0.593**

TG < 1.7

43(39.4)

340(36.8)

 

TG ≥ 1.7

66(60.6)

583(63.2)

 

LDL-C, mmol/L

2.82 ± 0.96

2.90 ± 0.84

0.374*

LDL-C categories

  

0.217**

LDL-C < 2.6

38(34.9)

269(29.1)

 

LDL-C ≥ 2.6

71(65.1)

654(70.9)

 

HDL-C, mmol/L

1.04 ± 0.26

1.08 ± 0.30

0.124*

HDL-C categories

  

0.987**

< 1 in male or < 1.3 in female

82(75.2)

695(75.3)

 

≥ 1 in male or ≥ 1.3 in female

27(24.8)

228(24.7)

 

Antidiabetic drugs

88(80.7)

779(84.4)

0.323**

OAD

52(47.8)

517(56.0)

0.099**

DPP-4 inhibitors

0(0)

6(0.7)

1.000**

Insulin

77(70.6)

695(75.3)

0.290**

Aspirin

35(32.1)

288(31.2)

0.847**

Lipid lowering drugs

44(40.4)

344(37.3)

0.528**

Statin

44(40.4)

326(35.3)

0.299**

fibrates

1(0.9)

20(2.2)

0.504**

OLLD

0(0)

5(0.5)

0.661**

Antihypertensive drugs

48(44.0)

365(39.5)

0.365**

Angiotensin drugs

30(27.5)

228(24.7)

0.520**

OAHD

40(36.7)

269(29.1)

0.103**

CVD

60(55.0)

294(31.9)

< 0.0001**

DR

10(9.2)

152(16.5)

0.048**

DN

19(17.4)

169(18.3)

0.822**

DPN

14(12.8)

83(9.0)

0.193**

  1. Data are represented as means ± standard deviation, n(%), median (interquartile range)
  2. BMI Body Mass Index, SBP systolic blood pressure, DBP diastolic blood pressure, HbA1c glycated haemoglobin, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, TG triglyceride, OAD oral antidiabetic drugs, DPP-4 dipeptidyl peptidase-4, OLLD other lipid lowering drugs, OAHD other antihypertensive drugs, CVD cardiovascular disease, DR diabetic retinopathy, DN diabetic nephropathy, DPN diabetic peripheral neuropathy
  3. *P-values for comparisons between groups derived by Student’s t-test
  4. **P-values for comparisons between groups derived by Chi squared test
  5. ***P-values for comparisons between groups derived by Wilcoxon Signed Rank Test
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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