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Fig. 6 | Diabetology & Metabolic Syndrome

Fig. 6

From: Glucose fluctuations aggravate myocardial fibrosis via activating the CaMKII/Stat3 signaling in type 2 diabtetes

Fig. 6

Role of CaMKII/Stat3 pathway in myocardial fibrosis induced by glucose fluctuation. Glucose fluctuation contributes to the upregulation of CaMKII phosphorylation, leading to Stat3 phosphorylation, and increased expression of fibrosis-related proteins.CaMKII, Ca2+/calmodulin‑dependent protein kinase II; Stat3, Signal transducer and activator of transcription 3

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