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Table 3 Echocardiographic indexes of left ventricular systolic function

From: The influence of dapagliflozin on cardiac remodeling, myocardial function and metabolomics in type 1 diabetes mellitus rats

 

C (n = 14)

DM (n = 15)

DM + DAPA (n = 13)

p value

PWSV (mm/s)

40 ± 3.84

34 ± 3.43 *

34 ± 3.81 *

< 0.001

Tei index

0.52 ± 0.05

0.58 ± 0.05 *

0.55 ± 0.04

0.004

Ejection fraction

0.85 ± 0.03

0.84 ± 0.04

0.83 ± 0.04

0.366

EFS (%)

47 ± 3.94

46 ± 5.20

45 ± 4.00

0.395

TDI S’ (average. cm/s)

3.56 ± 0.35

3.03 ± 0.24 *

3.15 ± 0.23 *

< 0.001

  1. C: control; DM: diabetes mellitus; DM + DAPA: DM treated with dapagliflozin; n: number of rats; PWSV: posterior wall shortening velocity; EFS: endocardial fractional shortening; TDI S’: tissue Doppler imaging for systolic velocity of the mitral annulus (average of lateral and septal walls). Data are means ± standard deviation. ANOVA and Tukey; * statistically different from C