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Table 1 Baseline characteristics of the study population both overall and according to quartiles of TyG index

From: Association of triglyceride-glucose index with cardiovascular disease among a general population: a prospective cohort study

Characteristicsa

TyG indexb

P for trendc

Total

Q1 (6.53–8.25)

Q2 (8.25–8.61)

Q3 (8.61–9.02)

Q4 (9.02–12.38)

N

42,651

10,662

10,663

10,663

10,663

 

Female

25,447 (59.7)

6,632 (62.2)

6,527 (61.2)

6,423 (60.2)

5,865 (55.0)

< 0.001

Age, years

55.7 ± 11.1

53.0 ± 13.0

55.8 ± 11.1

56.8 ± 10.0

57.2 ± 9.5

< 0.001

Education level

      

 Primary school and below

5,180 (12.2)

1,122 (10.5)

1,332 (12.5)

1,329 (12.5)

1,397 (13.1)

< 0.001

 Middle school

12,422 (29.1)

2,977 (27.9)

3,167 (29.7)

3,234 (30.3)

3,044 (28.6)

 

 High school or above

25,049 (58.7)

6,563 (61.6)

6,164 (57.8)

6,100 (57.2)

6,222 (58.4)

 

Current smoking

10,395 (24.4)

2,282 (21.4)

2,476 (23.2)

2,566 (24.1)

3,071 (28.8)

< 0.001

Current drinking

5,758 (13.5)

1,316 (12.3)

1,306 (12.3)

1,397 (13.1)

1,739 (16.3)

< 0.001

Physical activity level

      

 Low

4,173 (9.8)

1,007 (9.4)

996 (9.3)

1,029 (9.7)

1,141 (10.7)

< 0.001

 Moderate

13,803 (32.4)

3,707 (34.8)

3,369 (31.6)

3,304 (31.0)

3,423 (32.1)

 

 High

24,675 (57.9)

5,948 (55.8)

6,298 (59.1)

6,330 (59.4)

6,099 (57.2)

 

Body mass index, kg/m2

24.2 ± 3.3

22.8 ± 3.1

23.8 ± 3.2

24.7 ± 3.2

25.6 ± 3.1

< 0.001

Systolic blood pressure, mmHg

132.8 ± 19.3

127.0 ± 18.3

131.4 ± 18.8

134.5 ± 18.9

138.5 ± 19.4

< 0.001

Diastolic blood pressure, mmHg

79.6 ± 10.6

76.8 ± 10.2

79.0 ± 10.4

80.5 ± 10.3

82.6 ± 10.6

< 0.001

Uric acid, mg/dL

303.8 ± 80.7

276.8 ± 71.0

293.1 ± 74.0

310.8 ± 78.5

334.3 ± 86.8

< 0.001

Fasting plasma glucose, mmol/L

4.9 (4.4, 5.5)

4.5 (4.2, 4.8)

4.8 (4.3, 5.2)

5.0 (4.5, 5.5)

5.5 (4.9, 6.5)

< 0.001

Triglycerides, mmol/L

1.4 (1.0, 2.0)

0.8 (0.7, 0.9)

1.2 (1.1, 1.3)

1.7 (1.5, 1.9)

2.6 (2.2, 3.4)

< 0.001

Total cholesterol, mmol/L

4.9 ± 0.9

4.6 ± 0.8

4.9 ± 0.8

5.0 ± 0.9

5.3 ± 1.0

< 0.001

High-density lipoprotein cholesterol, mmol/L

1.4 ± 0.4

1.6 ± 0.4

1.5 ± 0.3

1.4 ± 0.3

1.2 ± 0.3

< 0.001

Low-density lipoprotein cholesterol, mmol/L

2.8 ± 0.8

2.6 ± 0.7

2.8 ± 0.8

2.9 ± 0.8

2.7 ± 1.0

< 0.001

HbA1c, %

5.7 (5.4, 6.0)

5.5 (5.2, 5.7)

5.6 (5.3, 5.9)

5.7 (5.4, 6.0)

5.9 (5.6, 6.5)

< 0.001

Hypertension

21,342 (50.0)

3,621 (34.0)

4,855 (45.5)

5,806 (54.5)

7,060 (66.2)

< 0.001

Antihypertensive medication

11,786 (27.6)

1,861 (17.5)

2,582 (24.2)

3,246 (30.4)

4,097 (38.4)

< 0.001

Diabetes

4,357 (10.2)

287 (2.7)

472 (4.4)

932 (8.7)

2,666 (25.0)

< 0.001

Antidiabetic medication

4,538 (10.6)

342 (3.2)

582 (5.5)

1,079 (10.1)

2,535 (23.8)

< 0.001

Dyslipidemia

14,770 (34.6)

938 (8.8)

1,786 (16.8)

3,342 (31.3)

8,704 (81.6)

< 0.001

  1.  N, number; Q, quartiles; TyG, triglyceride-glucose; HbA1c, glycated hemoglobin A1c
  2. a Continuous variables were described as mean ± standard deviation (SD); Categorical variables were described as frequency (percentage)
  3. b Exact values of quartiles of TyG index are as follows: (Q1) ≤ 8.246, (Q2) ≤ 8.609 and > 8.246, (Q3) ≤ 9.020 and > 8.609, and (Q4) > 9.020
  4. c For continuous variables, P for trend across quartiles of TyG index were calculated by the generalized linear regression analysis; for categorical variables, P for trend were calculated by the Cochran-Armitage trend chi-square test
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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