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Table 3 Cox regression analysis of the 1-SD increase in FI and frailty with all-cause mortality

From: Association of frailty index with congestive heart failure, all-cause and cardiovascular mortality among individuals with type 2 diabetes: a study from National Health and Nutrition Examination Surveys (NHANES), 1999–2018

 

Crude model

Model 1

Model 2

Model 3

HR (95%CI)

P

HR (95%CI)

P

HR (95%CI)

P

HR (95%CI)

P

FI

1-SD increase

1.44(1.32–1.56)

 < 0.0001

1.57(1.44–1.70)

 < 0.0001

1.50(1.38–1.64)

 < 0.0001

1.41(1.29–1.55)

 < 0.0001

Non-frailty

Ref

 

Ref

 

Ref

 

Ref

 

Frailty

2.04(1.73–2.41)

 < 0.0001

2.20(1.85–2.61)

 < 0.0001

2.08(1.76–2.45)

 < 0.0001

1.86(1.55–2.24)

 < 0.0001

  1. Crude model: no covariates were adjusted
  2. Model 1: age (continuous), gender, and race were adjusted
  3. Model 2: age (continuous), gender, race, education, smoking status, and alcohol consumption were adjusted
  4. Model 3: age (continuous), gender, race, education, smoking status, alcohol consumption, Obesity, systolic blood pressure, anti-diabetic drugs, HDL cholesterol, albumin, fasting plasma glucose, eGFR, and CHF were adjusted