Prognostic value of the prognostic nutritional index for patients with acute myocardial infarction undergoing percutaneous coronary intervention with variable glucose metabolism statuses: a retrospective cohort study

Table 3 The HR (95% CI) of cardiovascular mortality according to PNI and different glucose metabolism states from the three models

Glucose regulation state	PNI	Events, n (%)	Model 1		Model 2		Model 3
Glucose regulation state	PNI	Events, n (%)	HR (95% CI)	P value	HR (95% CI)	P value	HR (95% CI)	P value
Total	High	207/5856 (3.5)	Ref.		Ref.		Ref.
	Median	297/5895 (5.0)	1.209 (1.009, 1.449)	0.04	1.027 (0.857, 1.231)	0.774	0.97 (0.808, 1.166)	0.748
	Low	716/5910 (12.1)	2.24 (1.897, 2.644)	< 0.001	1.619 (1.364, 1.921)	< 0.001	1.296 (1.085, 1.549)	0.004
NGR	High	88/2474 (3.6)	Ref.		Ref.		Ref.
	Median	109/2321 (4.7)	1.133 (0.848, 1.514)	0.399	0.95 (0.71, 1.27)	0.727	0.949 (0.708, 1.27)	0.724
	Low	213/2119 (10.1)	1.848 (1.418, 2.408)	< 0.001	1.318 (0.999, 1.74)	0.051	1.209 (0.906, 1.612)	0.197
pre-DM	High	28/1456 (1.9)	Ref.		Ref.		Ref.
	Median	67/1616 (4.1)	1.772 (1.141, 2.752)	0.011	1.39 (0.896, 2.157)	0.142	1.236 (0.79, 1.932)	0.354
	Low	176/1669 (10.6)	3.671 (2.44, 5.524)	< 0.001	2.185 (1.43, 3.339)	< 0.001	1.765 (1.147, 2.716)	0.01
DM	High	91/1925 (4.7)	Ref.		Ref.		Ref.
	Median	121/1957 (6.2)	1.772 (1.141, 2.752)	0.011	1.001 (0.759, 1.32)	0.996	0.932 (0.704, 1.235)	0.625
	Low	327/2124 (15.4)	3.671 (2.44, 5.524)	< 0.001	1.775 (1.382, 2.28)	< 0.001	1.316 (1.009, 1.717)	0.043

PNI prognostic nutritional index, DM diabetes mellitus, pre-DM pre-diabetes mellitus, NGR normal glucose regulation, Ref. reference, HR hazard ratio, CI confidence interval
High: PNI > 48.2; median: 42.7 < PNI ≤ 48.2; low: PNI ≤ 42.7
Model 1: unadjusted
Model 2: adjusted for model 1 + age + gender
Model 3: adjusted for model 2 + HT + CHF + CKD + AF + stroke + anemia

ISSN: 1758-5996