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Fig. 9 | Diabetology & Metabolic Syndrome

Fig. 9

From: Celastrol attenuates streptozotocin-induced diabetic cardiomyopathy in mice by inhibiting the ACE / Ang II / AGTR1 signaling pathway

Fig. 9

The effects of celastrol on ACE/AngII/AGTR1 signaling pathway in DCM. (A, B) The molecular docking simulation of the binding pattern of celastrol with ACE. (C-E) Representative Western blot images and relative quantification of ACE and AGTR1, n = 3. (F) Quantification of ELISA assay of AngII expression in hearts, n = 6. *P < 0.05 vs. Control; # P < 0.05 vs. DCM + celastrol.

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