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Fig. 6 | Diabetology & Metabolic Syndrome

Fig. 6

From: Celastrol attenuates streptozotocin-induced diabetic cardiomyopathy in mice by inhibiting the ACE / Ang II / AGTR1 signaling pathway

Fig. 6

The effects of celastrol on diabetes-induced apoptosis. (A, C) Representative TUNEL staining images and relative quantification of TUNEL-positive cell in the hearts treated by STZ for 16 weeks. Scale bar = 20 μm. (B, D-F) Representative Western blot images and relative quantification of Bax, Bcl-2 and cleaved-caspase 3 of the hearts treated by STZ for 16 weeks. Data are shown as mean ± SD. n = 6, *P < 0.05 vs. Control; # P < 0.05 vs. DCM + celastrol.

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