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Fig. 4 | Diabetology & Metabolic Syndrome

Fig. 4

From: Celastrol attenuates streptozotocin-induced diabetic cardiomyopathy in mice by inhibiting the ACE / Ang II / AGTR1 signaling pathway

Fig. 4

The effects of celastrol on diabetes-induced cardiac fibrosis. (A) Representative Masson staining images of the hearts treated by STZ for 16 weeks. Magnification, 200×. (B) Quantification of ELISA assay of TGF-β expression in hearts. (C, D) Quantification of RT-PCR assay of COL1 and COL3 mRAN level. Data are shown as mean ± SD. n = 6, *P < 0.05 vs. Control; # P < 0.05 vs. DCM + celastrol.

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